顾月清博士,中国药科大学生命科学与技术学院生物医学工程学教授，博士生导师。国际光学工程协会（SPIE）及美国光学学会（OSA）会员，中国光学学会生物医学光子学专业委员会理事，中国电子学会医学影像专业委员会理事，中国生物医学工程学会分子影像分会理事，江苏省计量测试学会理事，江苏省生物医学工程生物光子学会理事，江苏省“青蓝工程”中青年学术带头人，多种国际杂志的特约审稿人（J.ControlledRelease,OpticsExpress,BioconjugateChemistry，CancerInvestigation,J.Fluorescence,JournalofPharmaceuticalScience,PharmaceuticalResearch），国家自然科学基金、教育部、科技部、部分省市科技厅等基金通讯及会议评审专家。
顾月清教授1997年于南京航空航天大学测试计量技术及仪器专业获得博士学位，1999年至2004年先后在美国宾州大学（UniversityofPennsylvania）医学院及德州大学(UniversityofTexas)西南医学中心从事博士后研究工作，并于2003年被聘为德州大学阿灵顿分校生物医学工程系助理教授。期间作为课题负责人获得美国国防部博士后基金及新研究者基金的资助，集中于近红外技术对乳腺癌及前列腺癌等的早期诊断及监测治疗研究。
顾月清教授于2005年回国后建立生物医学工程实验室，近年来一直致力于分子成像技术在药物研发各领域的应用，研究方向集中在如下四个方面：1）各种肿瘤特异性标志物的靶向分子探针的研究，以实现肿瘤的早期分子诊断；2）各种高分子纳米药物载体的研究，以实现肿瘤的主动/被动靶向治疗；3）从基因水平设计特异性DNA序列探针及分子信标，以研究肿瘤的生长、发展、转移等相关信号通路的关键蛋白，以研究肿瘤生长机制；4）开发各种荧光探针及光学检测系统，实现大分子药物体内动力学过程的无损在位实时监测及动力学特性研究；
自2006年，顾月清教授先后主持5项国家自然科学基金项目、指导3项国家自然基金青年基金项目、主持3项国际合作研究基金项目，参加科技部重大专项及多项省部级基金，申请及获国家发明专利8项。自2007年至今，共发表学术论文55篇，其中在国际权威杂志发表了SCI收录论文近30篇，总累计影响因子超过100、19篇EI收录研究论文。

在研项目：
国家自然科学基金重大国际（地区）合作研究项目（81220108012）
题目：面向乳腺肿瘤高转移机制的量子点小动物活体标记新方法的基础研究
时间：2013.1~2017.12经费：280万
分工：项目主持人(顾月清)
国家自然科学基金面上项目(81171395)
题目：基于SPR的纳米荧光分子探针活细胞内肿瘤药敏基因的检测及其穿膜特性的研究
时间：2012.1~2015.12经费：61万
分工：项目主持人(顾月清)

国家自然科学基金面上项目(30970776)：
题目：基于近红外量子点的分子成像对恶性肿瘤的代谢特性及特异性标志物的双重诊断
时间：2010.1~2012.12经费：33万
分工：项目主持人(顾月清)
国家自然科学基金外国青年学者研究基金(31050110123)：
题目：Measurementofcancer-relatedproteaseactivityusingactivatablefluorescentmolecularprobesinvivo
时间：2010.7~2012.6，经费：40万
分工：项目主持人WalterJohnAkersfromUSA,中方合作者：顾月清

近几年发表的论文：
DaweiDeng,YuqiChen,JieCao,JunmeiTian,ZhiyuQian,SamuelAchilefu,YueqingGu*,High-QualityCuInS2/ZnSQuantumDotsforinvitroandinvivoBioimaging,ChemistryofMaterials,2012,24(15),3029–3037.(IF=7.268)
HaiyanChen,ShulanLi,XueyanRen,ShengnanLi,YueqingGu*.Folate-modifiedgoldnanoclustersasnear-infraredfluorescentprobesfortumorimagingandtherapy.Nanoscale,2012,DOI:10.1039/C2NR31616A.(IF=5.914)
Haiyanchen,bowenLi,XueyanRen,ShengnanLiYuxiangMa,SisiCui,YueqingGu*.Multifunctionalnear-infrared-emittingnano-conjugatesbasedongoldclustersfortumorimagingandtherapy.Biomaterials,2012,http://dx.doi.org/10.1016/j.biomaterials.2012.08.034.(IF=7.404)
JianZhang,DaweiDeng,HongyanZhu,YoungroByun,VictorC.Yang,YueqingGu*,“Folate-conjugatedthermo-responsivemicellesfortumortargeting,JournalofBiomedicalMaterialsResearch:PartA,2012inpress

MahoungaDM,ShanLingling,JieCao,DuChangli,WanSunan,GuYueqing*,“SynthesisofaNovelL:-Methyl-Methionine-ICG-Der-02FluorescentProbeforInVivoNearInfraredImagingofTumors”,MolImagingBiol.2012May3.[Epubaheadofprint].

JianpengXue,HaiyanChen,BingXue,ZhiyuQian,WalterJ.Akers,SamuelAchilefu,YueqingGu*,“VisualDetectionofSTAT5BGeneExpressioninLivingCellusingthehairpinDNAmodifiedgoldnanoparticlesbeacon”,BiosensorsandBioelectronics(IF=5.1),2012，inpress.

JingChen,HaiyanChen,SisiCui,BingXue,JunmeiTian,SamuelAchilefu,YueqingGu*,GlucosamineDerivativeModifiedNanostructuredLipidCarriersforTargetedTumorDelivery,J.MaterialChemistry.2012,22,5770-5783(IF=5.1)SCI-CD

SisiCuia,HaiyanChena,,HongyanZhua,JunmeiTiana,XuemeiChia,ZhiyuQianb,SamuelAchilefuc,YueqingGua*,AmphiphilicChitosanModifiedUpconversionNanoparticlesforinvivoPhotodynamicTherapyInducedbyNear-infraredLight,J.MaterialChemistry.2012,22,4861-4873(IF=5.1)SCI-CD

JieCao,ShunanWan,JunmeiTian,SiwenLi,DongyinZhang,DaweiDeng,ZhiyuQian,YueqingGu*.FastClearingRGD-BasedNearInfraredFluorescentProbesforinvivoTumorDiagnosis.ContrastMediaandMolecularImaging,2012,7(4):390-402（IF=4.1）SCIE

JingGuo,ChangliDu,LinglingShan,HongyanZhu,BingXue,ZhiyuQian,SamuelAchilefu,YueqingGu*.Comparisonofnearinfraredfluorescentdeoxyglucoseprobeswithdifferentdyesfortumordiagnosisinvivo.ContrastMediaandMolecularImaging,2012,7(3):289-301(IF=4.1)SCIE

HuiLi,ZhenzhenTu(co-author),LianxiaoAn,ZhiyuQian,SamuelAchilefu,YueqingGu*.InhibitoryeffectsofERβonproliferation,invasionandtumorformationofMCF-7breastcancercells-prognosticationfortheuseofERβ-selectivetherapy.Pharmaceuticalbiology,2012,50(7):839-49(IF=0.638)SCIE

BingXue,DaweiDeng,JieCao,FeiLiu,XinLi,WalterAkers,SamuelAchilefu,andYueqingGu.SynthesisofNACCappedNearInfrared-EmittingCdTeSAlloyedQuantumDotsandApplicationforinvivoEarlyTumorImaging.DaltonTransactions,2012,41(16):4935-47(IF=3.647)SCI-CD

JieCao,HongyanZhu(co-author),DaweiDeng,BingXue,LipingTang,DidelMahounga,ZhiyuQian,YueqingGu*.InvivoNIRimagingwithPbSquantumdotsentrappedinbiodegradablemicelles.JournalofBiomedicalMaterialsResearch:PartA,2012,100(4):958-68(IF=3.1)SCI-CD

DaweiDeng,JunfeiXia,JieCao,LingzhiQu,JunmeiTian,ZhiyuQian,YueqingGu,ZhongzeGu.Forminghighlyfluorescentnear-infraredemittingPbSquantumdotsinwaterusingglutathioneassurface-modifyingmolecule.JColloidInterfaceSci.2012,367(1):234-40(IF=3.1)SCI

LinglingShan,JianpengXue,ZhiyuQian,SamuelAchilefu,YueqingGu*.ImprovedTargetingofLigand-ModifiedAdenovirusasaNewNearInfraredFluorescenceTumorImagingProbe.BioconjugateChemistry,2011,22:567-581.(IF=5.1)SCI

LinglingShan,SisiCui,ChangliDu,ShunanWan,ZhiyuQian,SamuelAchilefu,YueqingGu*.Apaclitaxel-conjugatedadenovirusvectorfortargeteddrugdeliveryfortumortherapy.Biomaterials,2011,33(1):146-162.(IF=7.8)SCI

HongyanZhu,FeiLiu,JingGuo,JianpengXue,ZhiyuQian,YueqingGu*.Folate-modifiedchitosanmicelleswithenhancedtumortargetingevaluatedbynearinfraredimagingsystem.CarbohydratePolymers,2011,86(3):1118-1129(IF=3.7)SCI

HaiyanChen,SisiCui,ZhenzhenTu,JinziJi,JunZhang,YueqingGu*.CharacterizationofCdHgTe/CdsQDsforNearInfraredFluorescenceImagingofSpinalColumninaMouseModel.PhotochemistryandPhotobiology,2011,87:72-81.(IF=2.8)SCI

HaiyanChen,LiLi,SisiCui,DiderMahounga,JunZhang,YueqingGu*.FolateConjugatedCdHgTeQuantumDotswithHightargetingAffinityandSensitivityforInvivoEarlyTumorDiagnosis.JFluoresc,2011,21:793~801.(IF=2.6)SCI

Fang-qiuLi,Shi-xinZhang,Lian-xiaoAn,YueqingGu*,“Invivomoleculartargetingeffectsofanti-Sp17-ICG-Der-02onhepatocellularCarcinomaevaluatedbyanopticalimagingsystem”,JournalofExperimental&ClinicalCancerResearch,2011,30:25（IF1.27）SCIE

DaweiDeng,JieCao,JunfeiXia,ZhiyuQian,YueqingGu*,ZhongzeGu,*andWalterJohnAkers,“Two-phaseApproachtoHighQuality,Oil-soluble,Near-infrared-emittingPbSQuantumdotsbyUsingVariousWater-solubleAnionPrecursors”,Eur.J.Inorg.Chem.2011(IF=2.941)SCI

JieCao,ShunanWan,JunmeiTian,XuemeiChi,ChangliDu,DaweiDeng,WeiR.Chen,YueqingGu*.SynthesisofdimericcyclicRGDbasednear-infraredprobeforinvivotumordiagnosis.Proc.ofSPIE,2012,accepted.EI

SisiCui,HongyanZhu,HaiyanChen,JunmeiTian,WeiR.Chen,YueqingGu*.Surfacemodificationofupconversionnanoparticleswithamphiphilicchitosanforcancercellimaging.Proc.ofSPIE,2012,accepted.EI

SisiCui,HaiyanChen,YueqingGu*,“ComparisonofTwoStrategiesfortheSynthesisofUpconvertingNanoparticlesasBiologicallabels”,JournalofPhysics:ConferenceSeries277（2012）012006(EI)
XuemeiChi,JieCao,ShunanWan,ChangliDu,WeiR.Chen,YueqingGu*.SynthesisandcharacterizationofNIR-triggeredpolyelectrolytemultilayercapsules.Proc.ofSPIE,2012,accepted.EI

JunmeiTian,ZhenzhenTu,WeiR.Chen,YueqingGu*.ERβregulatesmiR-21expressionandinhibitsinvasionandmetastasisincancercells.Proc.ofSPIE,2012,accepted.EI

JianpengXue,LinglingShan,ZhenzhenTu,HongyanZhu,HaiyanChen,DaweiDeng,ZhiyuQian,YueqingGu*.SynthesisofGoldnanoparticlebasedbeaconformeasurementofSTAT5bproteinexpression.Proc.ofSPIE,2011,7910:791001-1.EI

HaiyanChen,SisiCui(co-author),HongyanZhu,ZhenzhenTu,LinglingShan,JianpengXue,DaweiDeng,JunZhang,YueqingGu*.InvivomonitoringofOrgan-SelectivedistributionofCdHgTe/SiO2.Proc.ofSPIE,2011,7910:79100S-1.EI

JianZhang,DaweiDeng,YueqingGu*,“TheTargetingBehaviorofFolate-NanohydrogelEvaluatedbyNearInfraredImagingSysteminTumor-BearingMouseModel”PharmaceuticalResearch,2010,27(1):46-55.(IF=3.277)SCI

JieCao,BingXue,HuiLi,DaweiDeng,YueqingGu*.Facilesynthesisofhigh-qualitywater-solubleN-acetyl-L-cysteine-cappedZn1-xCdxSe/ZnScore/shellquantumdotsemittingintheviolet–greenspectralrange.JournalofColloidandInterfaceScience,2010,348,369-376.(IF=3.019)SCI

HaiyanChen,SisiCui,JunZhang,YueqingGu*,“FolatedconjugatedCdHgTequantumDotswithhightargetingaffinityandsensitivityforinvivoearlytumordiagnosis.JournalofFluorescence,2010.Inpress.(IF=2.1)SCI

FeiLiu,DaweiDeng,XinyangChen,ZhiyuQian,SamuelAchilefu,YueqingGu*,“Folate-polyethyleneglycolconjugatednearinfraredfluorescenceprobewithhightargetingaffinityandsensitivityforinvivoearlytumordiagnosis”,MolecularImaging&Biology,2010,Inpress(IF=2.467)SCIE

DaweiDeng,FeiLiu,JieCao,XinyangChen,andYueqingGu*,“SynthesisandTumorTargetingResearchofTwoNear-InfraredFluorescenceProbes”,ChineseJournalofLasers,2010,InPress.(EI)

JieCao,DaweiDeng*,YueqingGu*,“UniformMesoporousDye-DopedSilicaNanoparticlesasaMultifunctionalDrugCarrierforinvivoearlytumordiagnosis”,Proc.SPIE,2010,InPress.(EI)

TingLi,NanxiWang,LijiaChen,DaweiDeng,YueqingGu*,“Useofwater-solublePbSquantumdotsasfluorescentprobeinsensingcopper(II)”,Proc.SPIE,2010,InPress.(EI)
HongyanZhu,DaweiDeng,HaiyanChen,ZhiyuQian,YueqingGu,“Thetargetedbehavioroffolate-decoratedN-succinyl-N’-octylchitosanevaluatedbyNIRsysteminmousemodel”,Proc.SPIE,2010,InPress.(EI)

JieCao,BingXue,HuiLi,DaweiDeng*,YueqingGu*,“Facilesynthesisofhigh-qualitywater-solubleN-acetyl-L-cysteine-cappedZn1-xCdxSe/ZnScore/shellquantumdotsemittingintheviolet–greenspectralrange”,J.ColloidInterfaceSci.,2010,348,369–376.(IF=3.1)SCI

JieCao,ShanLi,DaweiDengandYueqingGu*,“Preparationandcharacterizationofwater-solublenear-infraredemissionPbSquantumdots”,TransactionsofNanjingUniversityofAeronautics&Astronautics,2010,27(1),81–87.

YueqingGu,FeiLiu,ChunshengFang,ZhiyuQian,SamuelAchilefu,“Invivoinvestigationofpharmacokineticsofmodeldrug:comparisonofnearinfraredtechniquewithhighperformanceliquidchromatography”Invitedpaper,Proc.SPIE,2010,vol.7576.EI

DaweiDeng,XinyangChen,JianZhang,FeiLiu,Jiecao,andYueqingGu*,“AqueoussynthesisofPbSquantumdotsfornoninvasivenear-infraredfluorescenceimaginginamousemodel”,Proc.SPIE,2010,Vol.7576.EI

JieCao,HongyanZhua,DaweiDeng,BingXue,LipingTang,DidelMahounga,ZhiyuQian,YueqingGu*,FacileSynthesisofNear-InfraredPbSQuantumDotsforInVivoTracingofMicelles,submittedtophysicalchemistrychemicalphysics(IF=4.116)

Jianzhang,YueqingGu*,“Invivoanti-tumorefficacyofdocetaxel-loadedthermallyresponsivenanohydrogel”,Nanotechnology,Vol.20,pp325102-325109,2009.（IF=3.137）SCI

HuiminQian,YueqingGu*,MinWangandSamuelAchilefu,“OptimizationoftheNear-InfraredFluorescenceLabelingforInVivoMonitoringofaProteinDrugDistributioninAnimalModel”,J.Fluoresc.(2009)19:277–284.（IF=2.017）SCI

YueqingGu*,JianZhang,HaiyanChen,andZhiyuQian,“Dynamicpropertiesofdifferentkindsofnanoparticlesinmousemodelafterintravenousadministration”Proc.SPIE,(2009)7190,71900F.(EI)

XinyangChen,DaweiDeng,zhiyuQian,YueqingGu*,“Invivotumorimaginginmicewithnear-infrared-lowdensitylipoproteinconjugates”,Proc.SPIE,2009,Vol.7519,75190P.(EI)
DaweiDeng,WenhaoZhang,XinyangChen,FeiLiu,JianZhang,YueqingGu*,andJianmingHong,“FacileSynthesisofHigh-Quality,Water-Soluble,Near-Infrared-EmittingPbSQuantumDots”,Eur.J.Inorg.Chem.2009,3440–3446.（IF=2.941）SCI

DaweiDeng,PengLi,andYueqingGu*,“SynthesisandstructuralanalysisofangledTenanocrystals”Cryst.Res.Technol.2009,44,No.6,629–635.（IF=2.293）SCI

DaweiDeng,andYueqingGu*,“Spontaneoustransitionandconcomitantself-assemblyofCdTenanoparticlesintoCdSnanosheetsinducedbyL-cysteine”,Proc.ofSPIE,2009,Vol.7190.EI

JianZhang,LinXu,YueqingGu*,“ThetargetedbehaviorofthermallyresponsivenanohydrogelevaluatedbyNIRsysteminmousemodel”J.controlledrelease.131:34-40,2008..(IF=5.949)
SCI

HaiyanChen,YueqingGu*,YuzhuHu,Realtimeinvivonon-invasiveopticalimagingoftemperaturesensitiveco-polymericnanohydrogel,Nanotechnology,2008,19,18570.（IF=3.137）SCI

HuiminQianYueqingGu*,Minwang,SamuelAchilefu,“Optimizationofthenear-infraredfluorescencelabelingforinvivomonitoringofaproteindrugdistributioninanimalmodel”JFluorescence,2008(Epubaheadofprint)（IF=2.017）SCI

YueqingGu,ZhiyuQian,YunliSong,InVivoNearInfraredTechniquesforProteinDrugDevelopment,EncyclopaediaofHeathcareInformationSystem,Bookchapter,2008

HaiyanChen,YuanqingWang,JingXu,JianZhang,YuzhuHu,YueqingGu*,Non-invasiveNearInfraredFluorescenceImagingofCdHgTeQuantumDotsinMouseModel.JFluoresc.18(5):801-11,2008(IF=2.017)SCI

HaiyanChen,YueqingGu*,YuzhuHu,“Comparisonoftwopolymericcarrierformulationsforcontrolledreleaseofhydrophilicandhydrophobicdrugs”,JournalofMaterialsScience:MaterialsinMedicine,2008Feb;19(2):651-8.(IF=1.955)SCI

HaiyanChen,YueqingGu*,YuzhuHu,ZhiyuQian,“CharacterizationofpHandtemperaturesensitivehydrogennanoparticleforcontrolleddrugrelease,PDAJournalofPharmaceuticalScienceandTechnology,2007,Jul-Aug;61(4):303-13

HaoGao,YueqingGu*,QingnengPing*,“Theimplantable5-fluororacil-loadedpoly(L-lacticacid)fiberspreparedbywet-spinningfromsuspension”,JournalofControlledRelease,2007Apr;118(3):325-32.(IF=5.949)SCI

ChunshengFang,YueqingGu.Near-infraredfluorescencelabelingandinvivomonitoringofthedynamicsofinsulininmousemodel,The6thinternationalconferenceonphotonicsandimaginginbiologyandmedicine.2007