曾琳琳
姓名： 曾琳琳

职称： 讲师
最高学位： 博士
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工作地点： 生命科学楼369室
研究方向： 主要从事研究神经系统退行性疾病阿尔茨海默氏症（Alzheimer disease，AD）及肌萎缩性脊髓侧索硬化症（Amyotrophic lateral sclerosis，ALS）的发病机制。
教育经历： 2007/09-2012/12 博士 研究生
吉林大学生命科学学院 Edmond H. Fischer实验室 微生物与生化药学专业
2002/09-2007/07 学士
吉林大学药学院 生物工程（医学）专业
工作经历： 2015/07-至今吉林大学生命科学学院 讲师
2013/01-2015/03 美国田纳西大学兽医学院生物医学与诊断学系 博士后
2010/05-2012/12 美国田纳西大学兽医学院生物医学与诊断学系
联合培养博士研究生

研究成果： 期刊论文
1.Linlin Zeng, Chen Hu, Fuqiang Zhang, Daniel C.Xu, Mei-Zhen Cui, Xuemin Xu. Cellular FLICE-like Inhibitory Protein (c-FLIP) and PS1-associated Protein (PSAP) Mediate Presenilin 1-induced γ-Secretase-dependent and -independent Apoptosis, Respectively. Journal of Biological Chemistry, 2015, 290(30):18269-80
2.Linlin Zeng, Ting Li, Derek C. Xu, Hennifer Liu, Guozhang Mao, MeipZhen Cui , Xueqi Fu, Xuemin Xu. Death Receptor 6 Induces Apoptosis Not through Type I or Type II Pathway, but via a Unique Mitochondria-dependent Pathway by Interacting with Bax Protein. Journal of Biological Chemistry, 2012, 287(34):29125-3
3.Chen Hu, Linlin Zeng, Mei-Zhen Cui, Xuemin Xu. Nicastrin is required for APP but not Notch processing, while Aph-1 is dispensable for processing of both APP and Notch. J Neurochem. 2015 Dec 30
4.Ting Li, Linlin Zeng, Wei Gao, Mei-zhen Cui, Xueqi Fu, Xuemin Xu. PSAP Induces a Unique Apaf-1 and Smac-dependent Mitochondrial Apoptotic Pathway Independent of Bcl-2 Family Proteins. Biochimica et Biophysica Acta (BBA), 2013 Mar, 1832(3):453-74
5.Fuqiang Zhang, Feng Hao, Dong An, Linlin Zeng, Yi Wang, Xuemin Xu, and Mei-Zhen Cui.The matricellular protein Cyr61 is a key mediator of platelet-derived growth factor-induced cell migration. Journal of Biological Chemistry, 2015, 290(13):8232-42

会议论文
1. Linlin Zeng, Fuqiang Zhang, Chen Hu, Ting Li, Mei-Zhen Cui, Xuemin Xu, Both PSAP and FLIP Mediate Presenilin 1-induced Apoptosis, Society for Neuroscience (SfN)’ 44th annual meeting, Washington, DC November 15, 2014
2. Linlin Zeng, Ting Li, Guozhang Mao, Mei-Zhen Cui, Xuemin Xu, Molecular mechanism of deathreceptor-6 (DR-6) -induced apoptosis. Society for Neuroscience (SfN)’ 41st annual meeting, Washington, DC, November 15, 2011