李子义，理学博士，吉林大学第一医院转化医学研究院教授、博士生导师、人类疾病动物模型国家地方联合工程实验室副主任、国家重点研发专项首席科学家、教育部“创新团队”带头人；中国动物学会生殖生物学分会常务理事，吉林省动物学会副理事长，吉林省干细胞学会秘书长，国际干细胞研究学会（ISSCR）会员。长期从事干细胞、胚胎发育及人类疾病动物模型构建等相关研究。先后主持和承担国家重点研发项目、国家转基因生物新品种培育重大专项、国家“973”计划课题、国家自然科学基金项目等多个国家级项目。在 J Clin Invest、Dev Biol、Sci Rep 等期刊发表SCI收录论文50余篇。
近五年代表性论文：
[1] Sheng Zhang, Xin Ma, Zhongwei Wang, Peng Zhang, Ziyi Li*. Production of transgenic cattle expressing lysine-rich polypeptide in milk by somatic cell nuclear transfer. Transgenic Res, 2019, 28: 317-325
[2] Yanhui Zhai, Wei Li, Zhiren Zhang, Yunqing Cao, Zhengzhu Wang, Sheng Zhang, Ziyi Li*. Epigenetic states of donor cells significantly affect the development of somatic cell nuclear transfer (SCNT) embryos in pigs. Mol Reprod Dev, 2018, 85(1): 26-37
[3] Sheng Zhang, Xin Chen, Fang Wang, Xinglan An, BoTang, Xueming Zhang, Liguang Sun*, Ziyi Li*. Aberrant DNA methylation reprogramming in bovine SCNT preimplantation embryos. Sci Rep, 2016, 26; 6:30345.
[4] Hou X, Liu J, Zhang Z, Zhai Y, Wang Y, Wang Z, Tang B, Zhang X, Sun L, Li Z*. Effects of cytochalasin B on DNA methylation and histone modification in parthenogenetically activated porcine embryos. Reproduction, 2016, 152(5):519-27.
[5] Xinglan An, Kuiying Ma, Zhiren Zhang, Tianchuang Zhao, Xueming Zhang, Bo Tang, and Ziyi Li*. miR-17, miR-21, and miR-143 Enhance Adipogenic Differentiation from Porcine Bone Marrow-Derived Mesenchymal Stem Cells. DNA and Cell Biology, 2016, 35(8): 410-416