姓名：孙文献
性别：男
毕业院校：Ohio University
最高学位：博士
职称：教授
办公地址：长春市新城大街2888号吉林农业大学
办公电话：
电子邮箱：wxs@cau.edu.cn

个人简介：
学习经历：
1988.09–1992.07：南京农业大学农学专业，本科学生，获得农学学士学位
1992.09–1995.07：南京农业大学，硕士研究生，获得作物遗传育种学硕士学位
1999.01–2003.12：Ohio University，博士研究生，获得生物学博士学位
工作经历
1995.08-1998.12 南京农业大学农学系细胞遗传研究所，助教、讲师
2004.01-2008.10威斯康星大学植物病理系，博士后
2008.11- 中国农业大学植物保护学院，教授，博士生导师
2016.05- 入选科技部中青年科技创新领军人才
2017.05- 入选国家“****”领军人才
2018.05- 入选教育部“****奖励计划”特聘教授
2018.05- 吉林农业大学植物保护学院，教授，博士生导师
2018.12- 吉林农业大学植物保护学院，院长
研究方向：
植物PAMP诱导抗性的分子机理
水稻与其病原菌的分子互作
水稻病原菌的毒性与致病力的分子基础

科研项目：
1. 吉林省技术攻关项目（SF），基于水稻病害生态防控的农药面源污染治理技术，2019.01-2021.12，50万元，在研，主持
2. 国家自然科学基金面上项目（31770140），细菌性条斑病菌效应蛋白XopE35抑制水稻免疫的分子机理，2018.1-2021.12，60万元，在研，主持
3. 国家自然科学基金重点项目 (31630064)，稻曲病菌致病关键效应蛋白的鉴定及其毒性功能的分子机理， 2017.1-2021.12， 284万元，在研，主持
4. 国家自然科学基金面上项目 (31471728)，稻曲病菌中稻曲菌素与黑粉菌素合成基因的鉴定及功能分析，2015.1-2018.12， 100万元，在研，主持
5. 农业部公益性行业专项（20130315）作物细菌性病害防控技术研究与示范 ， 2013.1-2017.12, 63万元，已结题，参与
6. 国家自然科学基金面上项目 (31272007)，水稻中 XA21 同源蛋白对条斑菌分子模式Ax21 的识别研究，2013.1-2016.12， 75万元，已结题，主持
7. 国家科技支撑计划（2012BAD19B03）子课题，水稻抗病性研究及北方稻区技术集成示范， 2012.1-2016.12，92万元，已结题，子课题主持
8. 国家973计划项目（2011CB100700）植物免疫机制与作物抗病分子设计的重大基础理论，2011.1-2015.10，77 万元，已结题，参与

荣誉与奖项：
2016年，中国农业大学教学成果一等奖，第五完成人。
2015年，辽宁省科技进步三等奖，“耐盐高抗水稻新品种盐粳456选育及应用”，排名第六
2015年，中国农业大学优秀教师

近年代表性学术成果：
论文：
1. Anfei Fang, Han Gao, Nan Zhang, Xinhang Zheng, Shanshan Qiu, Yuejiao Li,Shuang Zhou,
Fuhao Cui and Wenxian Sun*. A novel effector gene SCRE2 contributes to full virulence of Ustilaginoidea virens to Rice., Frontiers in Microbiology(4.019), doi: 10.3389/fmicb.2019.00845
2. Yuejiao Li#, Ming Wang, Zhaohui Liu, Kang Zhang, Fuhao Cui, Wenxian Sun^* (2019)Towards understanding the biosynthetic pathway for ustilaginoidin mycotoxins in Ustilaginoidea virens. Environ. Microbiol. , DOI: 10.1111/1462-2920.14572
3. Jiyang Wang, Shanzhi Wang, Ke Hu, Jun Yang, Xiaoyun Xin, Wenqing Zhou, Jiangbo Fan, Fuhao Cui, Baohui Mou, Shiyong Zhang, Guo-Liang Wang, Wenxian Sun ^*(2018) The kinase OsCPK4 regulates a buffering mechanism that fine-tunes innate immunity. Plant Physiol ,176: 1835-1849.
4. Qianqian Shi^#, Zhenchuan Mao, Xi Zhang, Xiaoping Zhang, Yunsheng Wang, Jian Ling, Runmao Lin, Denghui Li, Xincong Kang, Wenxian Sun, Bingyan Xie^*(2018) A Meloidogyne incognita effector MiISE5 suppresses programmed cell death to promote parasitism in host plant. Sci. Rep., 8:7256
5. Feng He^#, Fan Zhang, Wenxian Sun, Yuese Ning^*, Guo-Liang Wang^*(2018) A Versatile Vector Toolkit for Functional Analysis of Rice Genes. Rice, 11:27
6. Feng He^#, Fan Zhang, Wenxian Sun, Yuese Ning^*, Guo-Liang Wang^*(2018) Correction to: A Versatile Vector Toolkit for Functional Analysis of Rice Genes. Rice, 11:49
7. Fuhao Cui^#, Wenxian Sun, Xiangpei Kong (2018) RLCKs Bridge Plant Immune Receptors and MAPK Cascades. Trends Plant Sci., 23:1039-1041
8. Jiyang Wang,Shanzhi Wang,Ke Hu,Jun Yang,Xiaoyun Xin,Wenqing Zhou,Jiangbo Fan,Fuhao Cui,Baohui Mou,Shiyong Zhang,Guo-Liang Wang,Wenxian Sun (2017) The kinase OsCPK4 regulates a buffering mechanism that fine-tunes innate immunity. Plant Physiol.2018, 176, 1835–1849 Published December 2017. DOI: https://doi.org/10.1104/pp.17.01024
9. Kang Zhang, Tengjiao Li, Yuejiao Li, Zhi-Gang Li, Tom Hsiang, Ziding Zhang and Wenxian Sun (2017) Pathogenicity genes in Ustilaginoidea virens revealed by a predicted protein-protein interaction network. J Proteome Res. 16(3):1193-1206. doi: 10.1021/acs.jproteome.6b00720.
10. Guo T, Wang XW, Shan K, Sun Wenxian, Guo LY. The Loricrin-Like Protein (LLP) ofPhytophthora infestansIs Required for Oospore Formation and Plant Infection. Front Plant Sci. 2017 Feb 9;8:142. doi: 10.3389/fpls.2017.00142.
11. Lijuan Liu, Yanping Wang, Fuhao Cui, Anfei Fang, Shanzhi Wang, Jiyang Wang, Chao Wei, Shuai Li and Wenxian Sun*. The type III effector AvrXccB in Xanthomonas campestris pv. campestris targets putative methyltransferases and suppresses innate immunity in Arabidopsis. (2017) Mol. Plant Pathol. 18（6）：768-782. 10.1111/mpp.12435.
12. AnfeiFang,YanqingHan,NanZhang,MinZhang,LijuanLiu,ShuaiLi,FenLu, and Wenxian Sun*. Identification and characterization of plant cell death–inducing secreted proteins from Ustilaginoidea virens. (2016) Mol Plant Microbe Interact 29(5): 405-416.
13. Chao Wei, Wendi Jiang,Mengran Zhao, Junjie Ling, Xin Zeng, Jun Deng, Dongli Jin,John Maxwell Dowand Wenxian Sun*. A systematic analysis of the role of GGDEF-EAL domain proteins in virulence and motility inXanthomonas oryzaepv.oryzicola. Sci Rep. (2016) 6: 23769.
14. Jun-Jie Yu, Mi-Na Yu, Ya-Feng Nie, Wen-Xian Sun, Xiao-Le Yin, Jie Zhao, Ya-Hui Wang, Hui Ding, Zhong-Qiang Qi, Yan Du, Li Huang, Yong-Feng Liu. Comparative transcriptome analysis of fruiting body and sporulating mycelia of Villosiclava virens reveals genes with putative functions in sexual reproduction. (2016) Current Genetics 62(3): 575~584
15. Yanqing Han, Kang Zhang, Jun Yang, Nan Zhang, Anfei Fang, Yong Zhang, Yongfeng Liu, Zhiyi Chen, Tom Hsiang Wenxian Sun*. Differential expression profiling of the early response to Ustilaginoidea virens between false smut resistant and susceptible rice varieties. BMC Genomics (2015) 16:955.
16. Jun-jie Yu, Wen-xian Sun, Mi-na Yu, Xiao-le Yin, Xiang-kun Meng, Jie Zhao, Lei Huang, Li Huang and Yong-feng Liu (2015) Characterization of mating-type loci in rice false smut fungus Villosiclava virens. FEMS Microbiology Letters, 362, 2015 fnv014
17. Shuai Li, Yanping Wang, Shanzhi Wang, Anfei Fang, Jiyang Wang, Lijuan Liu, Kang Zhang, Yuling Mao and Wenxian Sun* (2015) The Type III Effector AvrBs2 in Xanthomonas oryzae pv. oryzicola suppresses rice immunity and promotes disease development. Mol Plant Microbe Interact 28(8): 869-80
18. Shanzhi Wang, Zhe Sun, Huiqin Wang, Lijuan Liu, Fen Lu, Jun Yang, Min Zhang, Shiyong Zhang, Zejian Guo, Andrew F. Bent, Wenxian Sun^* (2015) Rice FLS2-mediated perception of bacterial flagellins is evaded by Xanthomonas oryzae pvs. oryzae and oryzicola. Molecular Plant, 8:1024-1037.
19. Fangjun Li, Cheng Cheng, Fuhao Cui, Marcos V.V. de Oliveira, Xiao Yu, Xiangzong Meng, Aline C. Intorne, Kevin Babilonia, Maoying Li, Bo Li, Sixue Chen, Xianfeng Ma, Shunyuan Xiao, Yi Zheng, Zhangjun Fei, Richard P. Metz, Charles D. Johnson, Hisashi Koiwa1, Wenxian Sun, Zhaohu Li, Gon?alo A. de Souza Filho, Libo Shan, Ping He (2014) Modulation of RNA Polymerase II Phosphorylation Downstream of Pathogen Perception Orchestrates Plant Immunity. Cell Host & Microbe 16(6): 748-758
20. Fen Lu, Huiqin Wang, Shanzhi Wang, Wendi Jiang, Changlin Shan, Bin Li, Jun Yang, Shiyong Zhang, Wenxian Sun* (2015) Enhancement of innate immune system in monocot rice by transferring the dicotyledonous elongation factor Tu receptor. Journal of Integrative Plant Biology, 57(7): 641-652
21. Jing Fan, Xiao-Yi Guo, Liang Li, Fu Huang, Wenxian Sun, Yan Li, Yan-Yan Huang, Yong-Ju Xu, Jun Shi, Yang Lei, Ai-Ping Zheng and Wen-Ming Wang (2015) Infection of Ustilaginoidea virens intercepts rice seed formation but activates grain-filling-related genes. Journal of Integrative Plant Biology, 57(6):577-590.
22. Yong Zhang, Kang Zhang, Anfei Fang, Yanqing Han, Jun Yang, Minfeng Xue, Jiandong Bao, Dongwei Hu, Bo Zhou, Xianyun Sun, Shaojie Li, Ming Wen, Nan Yao, Li-Jun Ma, Yongfeng Liu, Min Zhang, Fu Huang, Chaoxi Luo, Ligang Zhou, Jianqiang Li, Zhiyi Chen, Jiankun Miao, Shu Wang, Jinsheng Lai, Jin-Rong Xu, Tom Hsiang, * Youliang Peng, * Wenxian Sun (2014) Specific adaptation of Ustilaginoidea virens in occupying host florets revealed by comparative and functional genomics, Nature Communications 5:3849, DOI: 10.1038/ncomms4849；
23. Xianyun Sun, Shu Kang, Yongjie Zhang, Xinqiu Tan, Yufei Yu, Haiyong He, Xinyu Zhang, Yongfeng Liu, Shu Wang, Wenxian Sun, Lei Cai, Shaojie Li (2013) Genetic Diversity and Population Structure of Rice Pathogen Ustilaginoidea virens in China. PLoS ONE 8(9): e76879
24. Tijiang Shan, Weibo Sun, Xiaohan Wang, Xiaoxiang Fu, Wenxian Sun and Ligang Zhou (2013) Purification of Ustiloxins A and B from Rice False Smut Balls by Macroporous Resins. Molecules 18:8181-8199.
25. Fuhao Cui, Shujing Wu, Wenxian Sun, Gitta Coaker, Barbara Kunkel, Ping He, and Libo Shan. (2013) The Pseudomonas syringae Type III Effector AvrRpt2 promotes pathogen virulence via stimulating Arabidopsis auxin/indole acetic acid protein turnover. Plant Physiology 162: 1018-1029
26. Yuanbao Zhang, Chao Wei, Wendi Jiang, Lei Wang, Churui Li, Yunyue Wang, Maxwell Dow, Sun, Wenxian* (2013) The HD-GYP domain protein RpfG of Xanthomonas oryzae pv. oryzicola regulates synthesis of extracellular polysaccharides that contribute to biofilm formation and virulence on rice. PLoS ONE 8(3): e59428.
专利：
2016.01，一种从种传和土传媒介中定量检测稻曲病菌的方法,专利号：ZL 2014 1 0259131.中国农业大学，孙文献(#); 韩彦卿; 彭军; 张楠; 方安菲; 张亢
2015.05，一种球囊霉属真菌与芽孢杆菌的组合菌剂及其应用，专利号：CN 9.，青岛农业大学，刘润进; 谭树朋; 孙文献; 黄金光

著作：
1. Zhou, L., Lu, S., Shan, T., Wang, P., Sun, W., Chen, Z., and Wang, S. (2012). Chemistry and biology of mycotoxins from rice false smut pathogen. In: Mycotoxins: Properties, Applications and Hazards ISBN: 978-1-62100-609-1. Editors: Bryan Melborn and Jason C. Greene?2012 Nova Science Publishers, Inc. Chapter 4, 109-127.