姜秀娥 研究员
姜秀娥，中国科学院长春应用化学研究所研究员、博士生导师。2005年博士毕业于中科院长春应化所。2006年~2010年先后在德国Bielefeld大学、德国ULM大学及德国Karlsruhe技术研究所从事洪堡学者及博士后研究。2010年加入中科院长春应化所电分析化学国家重点实验室，组建独立科研团队。2013年获“优秀青年基金”资助。主要从事谱学电化学分析、纳米尺度细胞相互作用机制及效应的研究。在SCI期刊共发表论文89篇，以第一作者和通讯联系人在Proc. Natl. Acad. Sci. USA, J. Am. Chem. Soc. (3), Angew. Chem. Int. Ed. (4) , ACS Nano (2), Adv. Funct. Mater., Anal. Chem. (5)等SCI著名刊物发表文章72篇。授权发明专利4项。所发表的文章被SCI杂志他引3600余次。相关研究工作被Nat. Mater., Chem. Rev等论文大篇幅引用及正面评价，并受邀撰写学术专著2章，综述3篇。主持了包括中德国际合作及优秀青年科学基金（结题优秀）等在内的国家自然科学基金 5 项
教育和工作经历
2010.09-至今, 中科院长春应化所,电分析化学国家重点实验室,研究员
2010.01-2010.04, 德国Karlsruhe技术研究所, 博士后
2008.06-2009.12, 德国ULM大学, 博士后
2006.04-2008.05, 德国Bielefeld大学, 洪堡学者
2002.09-2005.12, 中科院长春应化所, 分析化学, 博士,
主要荣誉
2015年获得全国五一巾帼标兵称号
2013年获得国家自然科学基金优秀青年基金资助
2013年获得吉林省三八红旗手称号
研究方向
1. 谱学电化学分析
生物膜中蛋白和磷脂的种类及与外界环境作用过程中的结构变化决定了生物膜的功能。 发展新的分析方法对生物膜界面进行原位、实时分析， 以揭示相互作用过程中的结构变化， 对于探究生物学功能的本质至关重要。 针对这一关键科学问题，我们自主设计了电化学界面增强红外光谱光学装置，建立了基于电化学表面增强红外光谱的原位、实时、免标记分析方法 ，与可视化的荧光共聚焦显微镜结合，系统研究了仿生膜、细胞膜界面上的纳米材料和蛋白的相互作用，揭示了生物组分的结构变化及调控因素，并提出了生物学效应的新机制。
2. 纳米细胞相互作用的动态响应机制
细胞是生命的基本结构和功能单元。纳米尺度的物质(纳米材料或蛋白)与细胞作用可以诱发细胞内吞、调节胞内代谢、诱导或阻止细胞凋亡。发展新的分析方法揭示动态相互作用机制及调控因素是操控细胞活性的关键。 我们开展了一系列工作，围绕纳米细胞相互作用的动态响应机制进行了系统的研究，以揭示了纳米材料的动态结构变化与细胞响应的构效关系，实现细胞凋亡的促进或抑制，为肿瘤等重大疾病的治疗提供新的策略。
3. 多功能纳米材料的生物应用
近年来对癌细胞的生物学特征研究显示，实体肿瘤内部微环境显著区别于正常组织，肿瘤弱酸、乏氧、高谷胱甘肽水平等微环境特征不但可导致癌细胞对放疗、化疗等多种疗法产生耐受性，同时可促进癌细胞的分化、转移与免疫逃逸。因此，调控肿瘤微环境对于抑制癌细胞的分化和转移，提高治疗效果是非常重要的。针对这一关键科学问题，我们发展了多种基于多功能纳米材料的肿瘤微环境调控策略，有效改善肿瘤乏氧状态，干扰肿瘤微环境的氧化还原平衡，可在避免对正常组织的副作用的同时显著提高提高肿瘤对于多种治疗策略（如化疗、光动力治疗等）的疗效，实现对肿瘤等恶性细胞高选择性杀伤。
成果及论文
Highlights
Wenyao Zhen, Yang Liu, Wei Wang, Mengchao Zhang, Wenxue Hu, Xiaodan Jia, Chao Wang, and Xiue Jiang*. Specific “unlocking”nanozyme-based butterfly effect for breaking the evolutionary fitness of chaotic tumor. Angewandte Chemie-International Edition, 2020, 10.1002/anie.201916142.
Shanshan Li, Lie Wu, Xiaofei Zhang, and Xiue Jiang*. Water structure bonded to the phosphate groups at the electrified zwitterionic phospholipid membranes/aqueous interface. Angewandte Chemie-International Edition, 2020, 10.1002/anie.202000511.
Chao Wang, Fengjuan Cao, Yudi Ruan, Xiaodan Jia, Wenyao Zhen, and Xiue Jiang*. Specific generation of singlet oxygen through the russell mechanism in hypoxic tumors and GSH depletion by Cu-TCPP nanosheets for cancer therapy. Angewandte Chemie-International Edition, 2019, 58(29), 9846-9850.
Jing Bai, Xiaodan Jia, Wenyao Zhen, Wenlong Cheng* and Xiue Jiang*. A facile ion-doping strategy to regulate tumor microenvironments for enhanced multimodal tumor theranostics. Journal of the American Chemical Society, 2018, 140(1): 106−109.
Wenyao Zhen, Yang Liu, Lin Lin, Jing Bai, Xiaodan Jia, Huayu Tian*, and Xiue Jiang*. BSA-IrO2: catalase-like nanoparticles with high photothermal conversion efficiency and a high X-ray absorption coefficient for anti-inflammation and antitumor theranostics. Angewandte Chemie-International Edition, 2018, 57(32): 10309-10313
Lie Wu, Li Zeng, and Xiue Jiang*. Revealing the nature of interaction between graphene oxide and lipid membrane by surface-enhanced infrared absorption spectroscopy. Journal of the American Chemical Society, 2015, 137(32): 10052−10055.
Xiue Jiang, Martin Engelhard, Kenichi Ataka*, and Joachim Heberle. Molecular impact of the membrane potential on the regulatory mechanism of proton transfer in sensory rhodopsin II. Journal of the American Chemical Society, 2010, 132(31): 10808-10815.
Xiue Jiang#, Ekaterina Zaitseva#, Michael Schmidt, Friedrich Siebert, Martin Engelhard, Ramona Schlesinger, Kenichi Ataka, Reiner Vogel*, and Joachim Heberle*. Resolving voltage-dependent structural changes of a membrane photoreceptor by surface-enhanced IR difference spectroscopy. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 2008, 105(34): 12113-1211
2020
78. Wenyao Zhen, Yang Liu, Wei Wang, Mengchao Zhang, Wenxue Hu, Xiaodan Jia, Chao Wang, and Xiue Jiang*. Specific“unlocking”nanozyme-based butterfly effect for breaking the evolutionary fitness of chaotic tumor. Angewandte Chemie-International Edition, 2020, 10.1002/anie.201916142.
77. Shanshan Li, Lie Wu, Xiaofei Zhang, and Xiue Jiang*. Water structure bonded to the phosphate groups at the electrified zwitterionic phospholipid membranes/aqueous interface. Angewandte Chemie-International Edition, 2020, 10.1002/anie.202000511.
76. Wenyao Zhen, Wenxue Hu, Liang Dong, Shangjie An, and Xiue Jiang*. Nanomaterials for regulation of tumor microenvironment and theranostics. Nanoscale Advances, 2020, 10.1039/C9NA00816K.
75. Lie Wu, and Xiue Jiang*. Enhancing peroxidase activity of cytochrome c by modulating interfacial interaction forces with graphene oxide. Langmuir, 2020, 36(5), 1094−1102
2019
74. Xiaofei Zhang, Fengjuan Cao, Lie Wu and Xiue Jiang*. Understanding the synergic mechanism of weak interactions between graphene oxide and lipid membrane leading to extraction of lipids. Langmuir, 2019, 35(43), 14098-14107.
73. Fengjuan Cao, Lie Wu, Xiaofei Zhang, Shanshan Li, Chao Wang, Wenyao Zhen and Xiue jiang*. Dynamic surface properties of PEG-coated CuS nanoparticles alter their interaction with cells as revealed by surface-enhanced infrared spectroscopy. Nanoscale Advances, 2019, 1(11), 4268-4276.
72. Liang Dong, Chao Wang, Wenyao Zhen, Xiaodan Jia, Shangjie An, Zhiai Xu, Wen Zhang* and Xiue Jiang*. Biodegradable iron-coordinated hollow polydopamine nanospheres for dihydroartemisinin delivery and selectively enhanced therapy in tumor cells. Journal of Materials Chemsitry B, 2019, 7(40), 6172-6180.
71. Chao Wang, Xiaodan Jia, Wenyao Zhen, Mengchao Zhang* and Xiue Jiang*. Small-sized MOF-constructed multifunctional diagnosis and therapy platform for tumor. ACS Biomaterials Science & Engineering, 2019,5(9), 4435-4441.
70. Chao Wang, Fengjuan Cao, Yudi Ruan, Xiaodan Jia, Wenyao Zhen, and Xiue Jiang*.Specific generation of singlet oxygen through the russell mechanism in hypoxic tumors and GSH depletion by Cu-TCPP nanosheets for cancer therapy. Angewandte Chemie-International Edition, 2019, 58(29), 9846-9850.
69. Wenyao Zhen, Yang Liu, Xiaodan Jia, Lie Wu, Chao Wang, and Xiue Jiang*. Reductive surfactant-assisted one-step fabrication of a BiOI/BiOIO3 heterojunction biophotocatalyst for enhanced photodynamic theranostics overcoming tumor hypoxia. Nanoscale Horizons, 2019, 4(3), 720-726.
68. Wenyao Zhen, Shangjie An,Wei Wang, Yang Liu, Xiaodan Jia,Chao Wang, Mengchao Zhang, and Xiue Jiang*. Gram-scale fabrication of Bi@C nanoparticles through one-step hydrothermal method for dual-model imaging-guided NIR-II photothermal therapy. Nanoscale, 2019, 11(20), 9906–9911.
67. Yudi Ruan, Xiaodan Jia, Chao Wang, Wenyao Zhen, and Xiue Jiang*. Methylene blue loaded Cu−tryptone complex nanoparticles: a new glutathione-reduced enhanced photodynamic therapy nanoplatform. ACS Biomaterials Science & Engineering, 2019, 5(2): 1016-1022.
66. Wenyao Zhen, Wei Wang, Zhifang Ma, Jing Bai, Xiaodan Jia, Yudi Ruan, Chao Wang, Mengchao Zhang*，and Xiue Jiang*. Multienzyme-mimicking nanocomposite for tumor phototheranostics and normal cell protection. ChemNanoMat, 2019, 5(1): 101–109. （VIP文章）
65. Lie Wu, Jianlong Sun, and Xiue Jiang*. Surface-enhanced infrared absorption spectroscopy-surface sensitive in situ label-free spectroelectrochemistry. Journal of Electrochemistry, 2019, 25(2): 202-222.
2018
64. Jing Bai, Xiaodan Jia, Wenyao Zhen, Wenlong Cheng* and Xiue Jiang*. A facile ion-doping strategy to regulate tumor microenvironments for enhanced multimodal tumor theranostics. Journal of the American Chemical Society, 2018, 140(1): 106−109.
63. Wenyao Zhen, Yang Liu, Lin Lin, Jing Bai, Xiaodan Jia, Huayu Tian*, and Xiue Jiang*. BSA-IrO2: catalase-like nanoparticles with high photothermal conversion efficiency and a high X-ray absorption coefficient for anti-inflammation and antitumor theranostics. Angewandte Chemie-International Edition, 2018, 57(32): 10309-10313.
62. Lie Wu, and Xiue Jiang*. Proton transfer at the interaction interface of graphene oxide. Analytical Chemistry, 2018, 90 (17): 10223–10230.
61. Fengjuan Cao, Lie Wu, Yudi Ruan, Jing Bai, and Xiue Jiang*. In situ surface-enhanced infrared absorption spectroscopy of aqueous molecules with facile-prepared large-area reduced graphene oxide island film. Analytical Chemistry, 2018, 90(11), 6526−6531.
60. Yudi Ruan, Xiaodai Jia, Chao Wang, Wenyao Zhen, and Xiue Jiang*. Mn–Fe layered double hydroxide nanosheets: a new photothermal nanocarrier for O2-evolving phototherapy. Chemical Communications, 2018, 54(83): 11729-11732.
59. Jing Bai, Xiaodan Jia, Yudi Ruan, Chao Wang, and Xiue Jiang*. Photosensitizer-conjugated Bi2Te3 nanosheets as theranostic agent for synergistic photothermal and photodynamic therapy. Inorganic chemistry, 2018, 57 (16): 10180–10188.
58. Wenyao Zhen, Jing Bai, Xiaodan Jia, Lie Wu, and Xiue Jiang*. H2O2‑responsive MB–BSA–Fe(III) nanoparticles as oxygen generators for MRI‑guided photodynamic therapy. Journal of Analysis and Testing, 2018, 2(1):69–76.
2017
57. Zhifang Ma, Xiaodan Jia, Jing Bai, Yudi Ruan, Chao Wang, Jianming Li, Mengchao Zhang*, and Xiue Jiang*. MnO2 gatekeeper: an intelligent and O2-evolving shell for preventing premature release of high cargo payload core, overcoming tumor hypoxia, and acidic H2O2-sensitive MRI. Advanced Functional Materials, 2017, 27(4): 1604258. (IF=13.325)
56. Li Liu, Li Zeng, Lie Wu, and Xiue Jiang*. Revealing the effect of protein weak adsorption to nanoparticles on the interaction between the desorbed protein and its binding partner by surface-enhanced infrared spectroelectrochemistry. Analytical Chemistry, 2017, 89 (5): 2724–2730. (IF=6.042)
55. Li Zeng, Lie Wu, Li Liu, and Xiue Jiang*. The role of water distribution controlled by transmembrane potentials in the cytochrome c–cardiolipin interaction: revealing from surface-enhanced infrared absorption spectroscopy. Chemistry-A European Journal, 2017, 23(61): 15491-15497. (IF=5.160)
54. Xiaodan Jia, Jing Bai, Zhifang Ma, and Xiue Jiang*. BSA-exfoliated WSe2 nanosheets as a photoregulated carrier for synergistic photodynamic/photothermal therapy. Journal of Materials Chemistry B, 2017, 5(2): 269-278. (IF=4.776)
2016
53. Zhifang Ma, Mengchao Zhang, Xiaodan Jia, Jing Bai, Yudi Ruan, Chao Wang, Xuping Sun, and Xiue Jiang*. Fe(III)-doped two-dimensional C3N4 nanofusiform: a new O2-evolving and mitochondria-targeting photodynamic agent for MRI and enhanced antitumor therapy. Small, 2016, 12(39): 5477–5487.
52. Li Zeng, Lie Wu, Li Liu, and Xiue Jiang*. Analyzing structural properties of heterogeneous cardiolipin-bound cytochrome c and their regulation by surface-enhanced infrared absorption spectroscopy. Analytical Chemistry, 2016, 88(23): 11727−11733. (IF=6.350)
51. Jing Bai, Xiaodan Jia, Zhifang Ma, Xiue Jiang*, and Xuping Sun*. Polycatechol nanosheet: a superior nanocarrier for highly effective chemo-photothermal synergistic therapy in vivo. Nanoscale, 2016, 8(9): 5260-5267.
50. Yichen Wang, and Xiue Jiang*. Synthesis of cell-penetrated nitrogen-doped carbon dots by hydrothermal treatment of eggplant sepals. Science China-Chemistry, 2016, 59(7): 836-842.
49. Xiaofei Zhang, Li Zeng, Li Liu, Zhifang Ma, and Xiue Jiang*. Surface-enhanced infrared absorption spectroscopy and electrochemistry reveal the impact of nanoparticles on the function of protein immobilized on mimic biointerface. Electrochimica Acta, 2016, 211: 148–155.
48. Chao Wang, Jing Bai, Yuwei Liu, Xiaodan Jia, and Xiue Jiang*. Polydopamine coated selenide molybdenum: a new photothermal nanocarrier for highly effective chemo-photothermal synergistic therapy. ACS Biomaterials Science & Engineering, 2016, 2(11): 2011−2017.
47. Yudi Ruan, Lie Wu, and Xiue Jiang*. Self-assembly of nitrogen-doped carbon nanoparticles: a new ratiometric UV-vis optical sensor for the highly sensitive and selective detection of Hg2+ in aqueous solution. Analyst, 2016, 141(11): 3313-3318.
46. Zhifang Ma, Xiaolei Li, Xiaodan Jia, Jing Bai, and Xiue Jiang*. Folate-conjugated polylactic acid–silica hybrid nanoparticles as degradable carriers for targeted drug delivery, on-demand release and simultaneous self-clearance. ChemPlusChem, 2016, 81(7): 652–659.
45. Lie Wu, and Xiue Jiang*. Recent developments in methodology employed to study the interactions between nanomaterials and model lipid membranes. Analytical and Bioanalytical Chemistry, 2016, 408(11): 2743-2758.
44. Jing Bai, Chunhe Sun, and Xiue Jiang*. Carbon dots-decorated multiwalled carbon nanotubes nanocomposites as a high-performance electrochemical sensor for detection of H2O2 in living cells. Analytical and Bioanalytical Chemistry, 2016, 408(17): 4705–4714.
43. Lie Wu, and Xiue Jiang*. Research progress of interfacial interaction between graphene material and model biomembrane. Chinese Journal of Applied Chemistry, 2016, 33(12): 1343-1354.
2015
42. Lie Wu, Li Zeng, and Xiue Jiang*. Revealing the nature of interaction between graphene oxide and lipid membrane by surface-enhanced infrared absorption spectroscopy. Journal of the American Chemical Society, 2015, 137(32): 10052−10055.
41. Tiantian Wang, and Xiue Jiang*. Breaking of the phosphodiester bond: a key factor that induces hemolysis. ACS Applied Materials & Interfaces, 2015, 7 (1): 129–136.
40. Yuwei Liu#, Jing Bai#, Xiaodan Jia, Xiue Jiang*, and Zhuo Guo*. Fabrication of multifunctional SiO2@GN-Serum composites for chemo-photothermal synergistic therapy. ACS Applied Materials & Interfaces, 2015, 7(1): 112–121.
39. Zhifang Ma, Jing Bai, and Xiue Jiang*. Monitoring of the enzymatic degradation of protein corona and evaluating the accompanying cytotoxicity of nanoparticles. ACS Applied Materials & Interfaces, 2015, 7(32): 17614-17622.
38. Li Liu, Li Zeng, Lie Wu, and Xiue Jiang*. Label-free surface-enhanced infrared spectroelectrochemistry studies the interaction of cytochrome c with cardiolipin-containing membranes. Journal of Physical Chemistry C, 2015, 119 (8), 3990–3999.
37. Xuejuan Yang, Yihu Wang, Jing Bai, Xiaoying He*, and Xiue Jiang*. Large mesoporous carbons decorated with silver and gold nanoparticles by a self-assembly method: enhanced electrocatalytic activity for H2O2 electroreduction and sodium nitrite electrooxidation. RSC Advances, 2015, 5(4): 2956–2962 .
36. Tiantian Wang, Shoujun Zhu, and Xiue Jiang*. Toxicity mechanism of graphene oxide and nitrogen-doped graphene quantum dots in RBCs revealed by surface-enhanced infrared absorption spectroscopy. Toxicology Research, 2015, 4(4): 885-894.
35. Li Liu, Lie Wu, Li Zeng, and Xiue Jiang*. Label-free surface-enhanced infrared spectro-electro-chemical analysis of the Redox potential shift of cytochrome c complexed with a cardiolipin-containing lipid membrane of varied composition. Chinese Physics B, 2015, 24(12), 128201.
2014
34. Jing Bai, Yuwei Liu, and Xiue Jiang*. Multifunctional PEG-GO/CuS nanocomposites for near-infrared chemo-photothermal therapy. Biomaterials, 2014, 35(22): 5805-5813.
33. Zhifang Ma, Jing Bai, Yichen Wang, and Xiue Jiang*. Impact of shape and pore size of mesoporous silica nanoparticles on serum protein adsorption and RBCs hemolysis. ACS Applied Materials & Interfaces, 2014, 6(4): 2431-2438
32. Jing Bai, Tiantian Wang, Yichen Wang, and Xiue Jiang*. Effects of nanoparticle surface ligands on protein adsorption and subsequent cytotoxicity. Biomaterials Science, 2014, 2(4): 493-501.
31. Yichen Wang, and Xiue Jiang*. Hydrogen peroxide biosensor based on carbon supported ultrafine silver nanoparticles. Chinese Journal of Analytical Chemistry, 2014, 42(5): 689-694.
Before 2013
30. Yinhu Wang, Xuejuan Yang, Jing Bai, Xiue Jiang*, and Gungyin Fan. High sensitivity hydrogen peroxide and hydrazine sensor based on silver nanocubes with rich {100} facets as an enhanced electrochemical sensing platform. Biosensors & Bioelectronics, 2013, 43: 180-185.
29. Jing Bai, and Xiue Jiang*. A facile one-pot synthesis of copper sulfide-decorated reduced graphene oxide composites for enhanced detecting of H2O2 in biological environments. Analytical Chemistry, 2013, 85(17): 8095–8101.
28. Tiantian Wang, and Xiue Jiang*. Size-dependent stability of water-solubilized CdTe quantum dots and their uptake mechanism by live HeLa cells. ACS Applied Materials & Interfaces, 2013, 5(4): 1190–1196.
27. Yichen Wang, and Xiue Jiang*. Facile preparation of porous carbon nanosheets without template and their excellent electrocatalytic property. ACS Applied Materials & Interfaces, 2013, 5(22): 11597–11602.
26. Xuejuan Yang, Yinhu Wang, Yuwei Liu, and Xiue Jiang*. A sensitive hydrogen peroxide and glucose biosensor based on gold/silver core-shell nanorods. Electrochimica Acta, 2013, 108: 39-44.
25. Yichen Wang, Haibin Wu, and Xiue Jiang*. Facile-green synthesis of nitrogen-doped carbon-supported ultrafine silver catalyst with enhanced electrocatalytic property. Electrochimica Acta, 2013,108: 66-73.
24. Fengjuan Cao, Lixu Wang, Xiue Jiang*, and Liping Guo*. Investigation of the effects of surface chemistry on adsorption of albumin by surface-enhanced FTIR spectroscopy. RSC Advances, 2013, 3(38): 17214-17221.
23. Tiantian Wang, Jing Bai, Xiue Jiang*, and G. Ulrich Nienhaus. Cellular uptake of nanoparticles by membrane penetration: a study combining confocal microscopy with FTIR spectroelectrochemistry. ACS Nano, 2012, 6(2): 1251-1259.
22. Shourui Lin, Xiue Jiang*, Lixu Wang, Guihua Li, and Liping Guo. Adsorption orientation of horse heart cytochrome c on a bare gold electrode hampers its electron transfer. Journal of Physical Chemistry C, 2012, 116(1): 637-642.
21. Xuejuan Yang, Jing Bai, Yinhu Wang, Xiue Jiang*, and Xiaoying He*. Hydrogen peroxide and glucose biosensor based on silver nanowires synthesized by polyol process. Analyst, 2012, 137(18): 4362-4367.
20. Lixu Wang, and Xiue Jiang*. Bioanalytical applications of surface-enhanced infrared absorption spectroscopy. Chinese Journal of Analytical Chemistry, 2012, 40(7): 975-982.
19. Shourui Lin, Lixu Wang, Xiue Jiang*, and Liping Guo*. Studies on the molecular mechanism of electron transfer of cytochrome c modulated by gold nanoparticles in nano-sandwich architecture. Journal of Electrochemistry, 2012, 18(3): 264-269.
18. Xiue Jiang, Anna Musyanovych, Carlheinz Rocker, Katharina Landfester, Volker Mailander, and G. Ulrich Nienhaus*. Specific effects of surface carboxyl groups on anionic polystyrene particles in their interactions with mesenchymal stem cells. Nanoscale, 2011, 3(5): 2028-2035.
17. Xiue Jiang, Martin Engelhard, Kenichi Ataka*, and Joachim Heberle. Molecular impact of the membrane potential on the regulatory mechanism of proton transfer in sensory rhodopsin II. Journal of the American Chemical Society, 2010, 132(31): 10808-10815.
16. Xiue Jiang, Carlheinz Rocker, Margit Hafner, Stefan Brandholt, Rene M. Dorlich, and G. Ulrich Nienhaus*. Endo- and exocytosis of zwitterionic quantum dot nanoparticles by live HeLa cells. ACS Nano, 2010, 4(11): 6787-6797.
15. Xiue Jiang, Julia Dausend, Margit Hafner, Anna Musyanovych, Carlheinz Rocker, Katharina Landfester, Volker Mailander, and G. Ulrich Nienhaus*. Specific effects of surface amines on polystyrene nanoparticles in their interactions with mesenchymal stem cells. Biomacromolecules, 2010, 11(3): 748-753.
14. Xiue Jiang, Stefan Weise, Margit Hafner, Carlheinz Rocker, Feng Zhang, Wolfgang J. Parak, and G. Ulrich Nienhaus*. Quantitative analysis of the protein corona on FePt nanoparticles formed by transferrin binding. Journal of The Royal Society Interface, 2010, 7(S1): S5-S13.
13. Xiue Jiang#, Ekaterina Zaitseva#, Michael Schmidt, Friedrich Siebert, Martin Engelhard, Ramona Schlesinger, Kenichi Ataka, Reiner Vogel*, and Joachim Heberle*. Resolving voltage-dependent structural changes of a membrane photoreceptor by surface-enhanced IR difference spectroscopy. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 2008, 105(34): 12113-12117.
12. Xiue Jiang, Kenichi Ataka*, and Joachim Heberle. Influence of the molecular structure of carboxyl-terminated self-assembled monolayer on the electron transfer of cytochrome c adsorbed on an Au electrode: In situ observation by surface-enhanced infrared absorption spectroscopy. Journal of Physical Chemistry C, 2008, 112(3): 813-819.
11. Xiue Jiang, Anne Zuber, Joachim Heberle, and Kenichi Ataka*. In Situ monitoring of the orientated assembly of strep-tagged membrane proteins on the gold surface by surface enhanced infrared absorption spectroscopy. Physical Chemistry Chemical Physics, 2008, 10(42): 6381-6387.
10. Xiue Jiang, Yuling Wang, Xiaohu Qu, and Shaojun Dong*. Surface-enhanced resonance Raman spectroscopy and spectroscopy study of redox-induced conformational equilibrium of cytochrome c adsorbed on DNA-modified metal electrode. Biosensors & Bioelectronics, 2006, 22(1): 49-55.
9. Xiue Jiang, Lei Zhang, and Shaojun Dong*. Assemble of poly (aniline–co–o -aminobenzenesulfonic acid) three-dimensional tubal net-works onto ITO electrode and its application for the direct electrochemistry and electrocatalytic behavior of cytochrome c. Electrochemistry Communications, 2006, 8(7): 1137-1141.
8. Xiue Jiang, Li Shang, Yuling Wang, and Shaojun Dong*. Cytochrome c superstructure biocomposite nucleated by gold nanoparticle: Thermal stability and voltammetric behavior. Biomacromolecules, 2005, 6(6): 3030-3036.
7. Xiue Jiang, Junguang Jiang, Yongdong Jin, Erkang Wang, and Shaojun Dong*. Effect of colloidal gold size on the conformational changes of adsorbed cytochrome c: probing by circular dichroism, UV-visible, and infrared spectroscopy. Biomacromolecules, 2005, 6(1): 46-53.
6. Xiue Jiang, Lei Zhang, Junguang Jiang, Xiaohu Qu, Erkang Wang, andShaojun Dong*. A colloidal Au monolayer modulates the conformation and orientation of a protein at the electrode/solution interface. ChemPhysChem, 2005, 6(8): 1613-1621.
5. Xiue Jiang, Zheling Zhang, Hanying Bai, Xiaohu Qu, Junguang Jiang, Erkang Wang, and Shaojun Dong*. Effect of electrode surface microstructure on electron transfer induced conformation changes in cytochrome c monitored by in situ UV and CD spectroelectrochemistry. Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy, 2005, 61(5): 943-951.
4. Xiue Jiang, Li Shang, Zhenxin Wang, Shaojun Dong*. Spectrometric and voltammetric investigation of interaction of neutral red with calf thymus DNA: pH effect. Biophysical Chemistry, 2005, 118(1): 42-50.
3. Xiue Jiang, Zheling Zhang, Weimin Huang, Xiaoqiang Liu, Erkang Wang, and Shaojun Dong*. In-situ UV and CD spectroelectrochemistry investigation of the electrochemical reduction reaction inducing conformational transition of microperoxidase-11. Chemical Journal of Chinese Universities-Chinese, 2005, 26(2): 321-325.
2. Xiue Jiang, Xiaohu Qu, Lei Zhang, Zheling Zhang, Junguang Jiang, Erkang Wang, and Shaojun Dong*. pH-dependent conformational changes of ferricytochrome c induced by electrode surface microstructure. Biophysical Chemistry, 2004, 110(3): 203-211.
1. Xiue Jiang, Liping Guo*, and Xiguang Du. Electrochemistry and electrocatalysis of binuclear cobalt phthalocyaninehexasulfonate-surfactant film modified electrode. Talanta, 2003, 61(3): 247-256.
