Guang ZHU
朱广
PhD in Chemical Physics and Biophysics
The University of Maryland, 1992

Professor
Division of Life Science
Department of Chemical and Biological Engineering



(852) 2358 8705
gzhu@ust.hk
Room 5528
Personal Web

---

Google Scholar
7CGcNJ0AAAAJ

ORCID
0000-0003-3802-3446

Scopus ID
7402633181




Research Interest Publications Projects Teaching Assignment RPG Supervision Space used




Research Interest

---

Structural biology
Deoxyribonucleic acid (DNA) replication
Cancer
Chemical biology
Cellular and molecular mechanisms



Publications

---

All Years 123 2022 0 2021 4 2020 2 2019 5 2018 4 2017 3 2016 105

---

Expand All Collapse All


2021 4

Crystal structure of parallel G-quadruplex formed by the two-repeat ALS-and FTD-related GGGGCC sequence
Nucleic Acids Research, v. 49, (10), June 2021, p. 5881-5890
Geng, Yanyan; Liu, Changdong; Cai, Qixu; Luo, Zhipu; Miao, Haitao; Shi, Xiao; Xu, Naining; Fung, Chun Po; Choy, To To; Yan, Bing; Li, Ning; Qian, Peiyuan; Zhou, Bo; Zhu, Guang Article
Isotopically Dimethyl Labeling-Based Quantitative Proteomic Analysis Of Phosphoproteomes Of Soybean Cultivars
Biomolecules, v. 11, (8), August 2021, article number 1218
Moradi, Atieh; Dai, Shuaijian; Wong,Oi Ying; Zhu, Guang; Yu, Fengchao; Lam, Hon-Ming; Wang, Zhiyong; Burlingame, Alma L.; Lin, Chengtao; Afsharifar, Alireza; Yu, Weichuan; Wang, Tingliang; Li, Ning Article
Quantitative evaluation and comparison of two prodrug-activating suicide gene therapies on oral squamous cell carcinoma
American Journal of Cancer Research, v. 11, (4), 15 April 2021, p. 1672-1682
Xu, Naining; Tian, Honglei; Fung, Chun Po; Lin, Yuntao; Zhu, Guang; Shen, Yuehong; Yang, Hongyu Article
Simultaneous Real-Time Three-Dimensional Localization And FRET Measurement Of Two Distinct Particles
Nano Letters, v. 21, (18), 7 September 2021, p. 7479-7485
Chen, Xingxiang; Liu, Teng; Qin, Xianan; Nguyen, Quang Quan; Lee, Chanwoo; Lee, Sang Kwon; Ren, Yaguang; Chu, Jun; Zhu, Guang; Yoon, Tae-Young; Park, Chan Young; Park, Hyo Keun Article

2020 2

An Essential and Cell-Cycle-Dependent ORC Dimerization Cycle Regulates Eukaryotic Chromosomal DNA Replication
Cell Reports, v. 30, (10), March 2020, article number E6, p. 3323-3338
Amin, Aftab; Wu, Rentian; Cheung, Man Hei; Scott, John F.; Wang, Ziyi; Zhou, Zijing; Liu, Changdong; Zhu, Guang; Wong, Chris Kong Chu; Yu, Zhiling; Liang, Chun Article
Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA
Nucleic Acids Research, v. 48, (19), November 2020, p. 11146-11161
Xu, Naining; You, Yingying; Liu, Changdong; Balasov, Maxim; Lun, Lee Tung; Geng, Yanyan; Fung, Chun Po; Miao, Haitao; Tian, Honglei; Choy, To To; Shi, Xiao; Fan, Zhuming; Zhou, Bo; Akhmetova, Katarina; Din, Rahman Ud; Yang, Hongyu; Hao, Quan; Qian, Peiyuan; Chesnokov, Igor; Zhu, Guang Article

2019 5

A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K⁺ solution
Chemical Science, v. 10, (1), January 2019, p. 218-226
Liu, Changdong; Zhou, Bo; Geng, Yanyan; Tam, Dick Yan; Feng, Rui; Miao, Haitao; Xu, Naining; Shi, Xiao; You, Yingying; Hong, Yuning; Tang, Benzhong; Lo, Pik Kwan; Kuryavyi, Vitaly; Zhu, Guang Article
G-quadruplex structures formed by human telomeric DNA and C9orf72 hexanucleotide repeats
Biophysical Reviews, v. 11, (3), June 2019, p. 389-393
Liu, Changdong; Geng, Yanyan; Miao, Haitao; Shi, Xiao; You, Yingying; Xu, Naining; Zhou, Bo; Zhu, Guang Article
The Biophysical Society of Hong Kong (BPHK): past, present, and future
Biophysical Reviews, v. 11, (3), June 2019, p. 259-261
Zhu, Guang Article
The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA
Nucleic Acids Research, v. 47, (10), June 2019, p. 5395-5404
Geng, Yanyan; Liu, Changdong; Zhou, Bo; Cai, Qixu; Miao, Haitao; Shi, Xiao; Xu, Naining; You, Yingying; Fung, Chun Po; Din, Rahman Ud; Zhu, Guang Article
A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K⁺ solution
International Conference on Cell Science & Molecular Biology 2019, Paris, France, 8-10 July 2019
Zhu, Guang Conference paper

2018 4

Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites
Communications Chemistry, v. 1, (1), December 2018, article number 62
Beteck, Richard M.; Seldon, Ronnett; Coertzen, Dina; Van der watt, Mari?tte E.; Reader, Janette; Mackenzie, Jared S.; Lamprecht, Dirk A.; Abraham, Matthew; Eribez, Korina; Müller, Joachim; Feng, Rui; Zhu, Guang; De grano, Ruel Valerio Robles; Williams, Ian Duncan; Smit, Frans J.; Steyn, Adrie J. C.; Winzeler, Elizabeth A.; Hemphill, Andrew; Birkholtz, Lyn-Marie; Warner, Digby F.; N’da, David D.; Haynes, Richard K. Article
Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence
Scientific Reports, v. 8, (1), February 2018, article number 2366, p. 2366-2366
Zhou, Bo; Geng, Yanyan; Liu, Changdong; Miao, Haitao; Ren, Yaguang; Xu, Naining; Shi, Xiao; You, Yingying; Lee, Tung Lun; Zhu, Guang Article
Responsive Upconversion Nanoprobe for Monitoring and Inhibition of EBV-Associated Cancers via Targeting EBNA1
Nanoscale, v. 10, (33), 7 September 2018, p. 15632-15640
Zha, Shuai; Fung, Yan Ho; Chau, Ho-Fai; Ma, Ping’an; Lin, Jun; Wang, Jin; Chan, Lai Sheung; Zhu, Guang; Lung, Hong Lok; Wong, Ka-Leung Article
G-quadruplex Structures Formed by Human Telomeric DNA and C9orf72 Hexanucleotide Repeats
The 10th Asian Biophysics Association Symposium (ABA 2018) in conjunction with the Australian Society for Biophysics (ASB) Meeting, Melbourne, Australia, 2-6 December 2018
Zhu, Guang Conference paper

2017 3

Mechanistic study of human DNA replication proteins that regulate cell proliferation and differentiation
2nd International Cancer Study & Therapy Conference, Baltimore, USA, 20-22 February 2017
Zhu, Guang Conference paper
Structure-functional Study of G-rich Oligonucleotides
2nd International Conference on Nucleic Acids, Molecular Biology & Molecular Medicine, Philadelphia, Pennsylvania, USA, 31 August - 1 September 2017
Zhu, Guang Conference paper
Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD
Society of Chinese Bioscientists in America the 16th International Symposium (2017 SCBA) 全球华人生物学家大会暨 第十六届美洲华人生物科学学会学术研讨会, Hangzhou, China, 29 Jun - 3 Jul 2017
Zhou, Bo; Liu, Changdong; Geng, Yanyan; Zhu, Guang Conference paper

2016 3

Mechanistic Study of Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Mediated Latent DNA replication in Human Cells
2nd World Congress on Cancer and Prevention Methods, Furama RiverFront, Singapore, 7-9 November 2016
Zhu, Guang Conference paper
Mechanistic Study of Epstein-Barr Virus Nuclear Antigen 1(EBNA1) Mediated DNA Replication in Human Cells
BIT's 14th Annual Congress of International Drug Discovery Science and Technology-South Korea 2016 (IDDST-South Korea 2016), Gyeonggi, South Korea, 16-18 June 2016
Zhu, Guang Conference paper
与ALS/FTD相关联的C9orf72六核苷酸重复扩增所形成G-四链体DNA的拓扑结构
第十九届全国波谱学学术会 The 19th Chinese National Magnetic Resonance Conference, Lan Zhou, China, 17-20 August 2016
周波; 刘长东; 耿艳艳; 朱广 Conference paper

2015 7

Development of stapled helical peptides to perturb the Cdt1-Mcm6 interaction
Journal of Peptide Science, v. 21, (7), July 2015, p. 593-598
Lee, Jonghan Peter; Liu, Changdong; Li, Tianlu; Zhu, Guang; Li, Xuechen Article
Quadruplex Nucleic Acid Structure Determination by Solution NMR
Chinese Journal of Magnetic Resonance=波谱学杂志, v. 32, (2), June 2015, p. 150-162
Liu, Changdong; Zhu, Guang Article
Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD
Scientific Reports, v. 5, November 2015, article number 16673
Zhou, Bo; Liu, Changdong; Geng, Yanyan; Zhu, Guang Article
Mechanistic Study of Human DNA Replication Initiation and Relating Diseases
BIT's 6th Annual World Gene Convention - 2015, Qingdao, China, 13-15 November 2015
Zhu, Guang Conference paper
Mechanistic study of human proteins that regulate cell proliferation and differentiation
World congress on Cancer and Prevention Methods, Dubai, UAE, 27-29 August 2015
Zhu, Guang Conference paper
Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation
9th Asian Biophysics Association Symposium, Hangzhou, China, 9-12 May 2015
Zhu, Guang Conference paper
Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad
The 22nd Symposium on Chemistry Postgraduate Research in Hong Kong, Hong Kong Baptist University, Hong Kong, 18 April 2015
Sun, Yueru; Yin, Shuhui; Feng, Yitao; Li, Jie; Zhou, Jiahai; Liu, Changdong; Zhu, Guang; Guo, Zhihong Conference paper

2014 4

Molecular basis of the general base catalysis of an α/β- hydrolase catalytic triad
Journal of Biological Chemistry, v. 289, (22), May 2014, p. 15867-15879
Sun, Yueru; Yin, Shuhui; Feng, Yitao; Li, Jie; Zhou, Jiahai; Liu, Changdong; Zhu, Guang; Guo, Zhihong Article
Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation
The 4th World Congress on Cancer Science & Therapy, Chicago, USA, 20-22 October 2014
Zhu, Guang Conference paper
Molecular Basis of the General Base Catalysis of an α/β-Hydrolase Catalytic Triad
The 2nd South China Structural Biology Symposium, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, 5-7 December 2014
Sun, Yueru; Yin, Shuhui; Feng, Yitao; Li, Jie; Zhou, Jiahai; Liu, Changdong; Zhu, Guang; Guo, Zhihong Conference paper
Structure-functional study of human pre-replication complex
Chinese NMR society, Hanzhou, China, 14-16 October 2014
Zhu, Guang Conference paper

2013 4

Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation
The 12th Conference of the Asian Crystallographic Association, The Hong Kong University of Science and Technology, Hong Kong, 7-10 December 2013
Zhu, Guang Conference paper
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
The 8th symposium of Asian Biophysics Association, Jeju Island, Korea, 26 - 29 May 2013
Zhu, Guang Conference paper
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
BIT's Biopharmaceutical Summit-2013, Frankfurt, Germany, 7 - 8 August 2013
Zhou, Bo; Liu, Changdong; Geng, Yanyan; Zhu, Guang Conference paper
The Chair-type Structure of the Intramolecular Human Telomeric G-quadruplex
BCEIA 2013 - The 15th Beijing Conference and Exhibition on Instrumental Analysis, Beijing, China, 23-26 October 2013
Liu, Changdong; Zhou, Bo; Feng, Rui; Zhu, Guang Conference paper

2012 8

Dynamic Nuclear Polarization: New Methodology and Applications
Topics in Current Chemistry, v. 326, 2012, p. 215-242
Sze, Kong Hung; Wu, Qinglin; Tse, Ho Sum; Zhu, Guang Article
NMR of Proteins and Small Biomolecules Preface
Topics in Current Chemistry, v. 326, 2012, p. IX-X
Zhu, Guang Article
Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode
Journal of biological chemistry, v. 287, (31), July 2012, p. 26104-26114
Chen, Lihong; Liu, Changdong; Ko, Frankie Chi Fat; Xu, Naining; Ng, Irene Oi-Lin; Yam, Judy Wai Ping; Zhu, Guang Article
Structural basis for homeodomain recognition by the cell-cycle regulator Geminin
Proceedings of the National Academy of Sciences of the United States of America, v. 109, (23), June 2012, p. 8931-8936
Zhou, Bo; Liu, Changdong; Xu, Zhiwen; Zhu, Guang Article
Structural insights into the Cdt1-mediated MCM2-7 chromatin loading
Nucleic Acids Research, v. 40, (7), April 2012, p. 3208-3217
Liu, Changdong; Wu, Rentian; Zhou, Bo; Wang, Jiafeng; Wei, Zhun; Tye, Bik Kwoon; Liang, Chun; Zhu, Guang Article
Crowding effect on calmodulin bakcbone dynamics
The 20th Symposium on Chemistry Postgraduate Research in Hong Kong, The Chinese University of Hong Kong, 27 April 2013
Feng, Yitao; Liu, Changdong; Wu, Qinglin; Zhu, Guang; Guo, Zhihong Conference paper
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
Joint Scientific Meeting of Hong Kong Society of neurosciences and the Biophysical Society of Hong Kong, Hong Kong, June 2012
Zhu, Guang Conference paper
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
BIT's 3rd Annual World Congress of Biomarkers - 2012, GuangZhou, China, 2- 4 Dec 2012
Zhu, Guang Conference paper

2011 6

¹H, ¹⁵N and ¹³C chemical shift assignments of the SH2 domain of human tensin2 (TENC1)
Biomolecular NMR Assignments, v. 5, (2), October 2011, p. 211-214
Chen, Lihong; Liu, Changdong; Rui, Feng; Zhu, Guang Article
1H, 15N chemical shift assignments of the imino groups in the base pairs of Escherichia coli tRNALeu (CAG)
Biomolecular NMR assignments, v. 5, (1), April 2011, p. 71-74
Hao, Zhan-Xi; Feng, Rui; Wang, En-Duo; Zhu, Guang Article
NMR of Proteins or Small Biomolecules, Advance Topics in Chemistry
NMR of Proteins or Small Biomolecules, Advance Topics in Chemistry / v. 326, 2011, Nov
Zhu, Guang Book
Recent development in DMP(chapter 8), Advance Topics in Chemistry
Recent development in DMP(chapter 8), Advance Topics in Chemistry, / Nov.30
Sze, Konghong; Wu, Qinglin; Zhu, Guang Book chapter
Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6
7th Asian Biophysics Association (ABA) Symposium & Annual Meeting of the Indian Biophysical Society (IBS), New Delhi, India, 30 January - 2 February 2011
Wei, Zhun; Liu, Changdong; Xu, Naining; Zhou, Bo; Zhu, Guang Conference paper
Characterization and Structure Determination of the Cdt1 Binding Domain of Human Minichromosome Maintenance (Mcm) 6
Protein & Peptide Conference, March 23-25, 2011 in Beijing, China
Zhu, Guang Conference paper

2010 7

¹H, ¹⁵N and ¹³C chemical shift assignments of the Cdt1 binding domain of human Mcm6
Biomolecular NMR Assignments, v. 4, (2), October 2010, p. 231-233
Liu, Changdong; Wei, Zhun; Zhu, Guang Article
Characterization and structure determination of the cdt1 binding domain of human minichromosome maintenance (Mcm) 6
Journal of Biological Chemistry, v. 285, (17), April 2010, p. 12469-12473
Wei, Zhun; Liu, Changdong; Wu, Xing; Xu, Naining; Zhou, Bo; Liang, Chun; Zhu, Guang Article
Solution structure of the dimerization domain of ribosomal protein P2 provides insights for the structural organization of eukaryotic stalk
Nucleic acids research, v. 38, (15), 2010, AUG, p. 5206-5216
Lee, Ka-Ming; Yu, Conny Wing-Heng; Chan, Denise So-Bik; Chiu, Teddy Yu-Hin; Zhu, Guang; Sze, Kong-Hung; Shaw, Pang-Chui; Wong, Kam-Bo Article
Studying base pair open-close kinetics of tRNA^Leu by TROSY-based proton exchange NMR spectroscopy
FEBS Letters, v. 584, (21), November 2010, p. 4449-4452
Hao, Zhan Xi; Tan, Min; Liu, Changdong; Feng, Rui; Wang, En Duo; Zhu, Guang Article
The interacting domains of hCdt1 and hMcm6 involved in the chromatin loading of the MCM complex in human cells
Cell Cycle, v. 9, (24), 2010, p. 4848-4857
Zhang, Jing; Yu, Lan; Wu, Xing; Zou, Lan; Sou, K.K.L.; Wei, Zhun; Cheng, Xue; Zhu, Guang; Liang, Chun Article
Characterization and structural determination of the Cdt1 binding domain of human Mcm6
Joint Scientific meeting of Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, University of Hong Kong, Jun 7-9, 2010
Wei, Zhun; Liu, Changdong; Xu, Naining; Zhou, Bo; Zhu, Guang Conference paper
Solution structure of the Cdt1 binding domain of human Mcm6
The 16th National Magnetic Resonance Conference of the CPS, Hainan, China, Nov 24-27, 2010
Liu, Changdong; Wei, Zhun; Xu, Naining; Zhou, Bo; Zhu, Guang Conference paper

2009 2

The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome
Nucleic acids research, v. 37, (2), 2009, FEB, p. 602-610
Too, Priscilla Hiu-Mei; Ma, Meiji Kit-Wan; Mak, Amanda Nga-Sze; Wong, Yuen-Ting; Tung, Christine Kit-Ching; Zhu, Guang; Au, Shannon Wing-Ngor; Wong, Kam-Bo; Shaw, Pang-Chui Article
Identification of the functional domains involved in the interaction between human Cdt1 and Mcm6
The Cold Spring Harbor Lab “Eukaryotic DNA Replication & Genome Maintenance” Meeting, Cold Spring Harbor Lab, N.Y., USA, 9/2009
Zhang, Jingjing; Wu, Xing; Yu, Lan; Wei, Zhun; Zou, Lan; Zhu, Guang; Liang, Chun Conference paper

2008 3

MH1 domain of SMAD4 binds N-terminal residues of the homeodomain of Hoxc9
Biochimica et Biophysica Acta - Proteins and Proteomics, v. 1784, (5), 2008, MAY, p. 747-752
Zhou, Bo; Chen, Lihong; Wu, Xing; Wang, Jing; Yin, Yinliang; Zhu, Guang Article
SET8 plays a role in controlling G(1)/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail
Cell cycle, v. 7, (10), 2008, MAY 15, p. 1423-1432
Yin, Yinliang; Yu, Vivian C.; Zhu, Guang; Chang, Donald C. Article
TROSY-based NMR experiments for NMR studies of large biomolecules
Progress in nuclear magnetic resonance spectroscopy, v. 52, (1), 2008, JAN 30, p. 49-68
Zhu, Guang; Yao, Xuejun Article

2007 1

Interaction between trichosanthin, a ribosome inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses
Nucleic acids research, v. 35, (5), 2007, p. 1660-1672
Chan, Denise S.B.; Chu, Lai-On; Lee, Ka-Ming; Too, Priscilla H.M.; Ma, Kit-Wan; Sze, Kong-Hung; Zhu, Guang; Shaw, Pang-Chui; Wong, Kam-Bo Article

2005 2

Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation
Molecular and cellular biology, v. 25, (9), 2005, MAY, p. 3575-3582
Ma, Kewei; Chan, Jonathan K.L.; Zhu, Guang; Wu, Zhenguo Article
SET8 recognizes the sequence RHRK²⁰VLRDN within the N terminus of histone H4 and mono-methylates lysine 20
Journal of Biological Chemistry, v. 280, (3)4, August 2005, p. 30025-30031
Yin, Yinliang; Liu, Changdong; Tsai, Sau Na; Zhou, Bo; Ngai, Sai Ming; Zhu, Guang Article

2004 8

(3,2)D GFT-NMR experiments for fast data collection from proteins
Journal of biomolecular NMR, v. 29, (4), 2004, AUG, p. 467-476
Xia, YL; Zhu, G.; Veeraraghavan, S.; Gao, XL Article
Elucidation of the solution conformations of loloatin C by NMR Spectroscopy and molecular simulation
European journal of organic chemistry, v.2004, (1), JAN, 2004, p. 31-37
Chen, Heru; Haynes, Richard K.; Scherkenbeck, Jürgen; Sze, Kong H.; Zhu, Guang Article
Escherichia coli tRNA₄^Arg(UCU) induces a constrained conformation of the crucial Ω-loop of arginyl-tRNA synthetase
Biochemical and biophysical research communications, v. 313, (1), 2004, JAN 2, p. 129-134
Yao, Yong-Neng; Zhang, Qing-Shuo; Yan, Xian-Zhong; Zhu, Guang; Wang, En-Duo Article
Protein flexibility and intrinsic disorder
Protein science, v. 13, (1), 2004, JAN, p. 71-80
Radivojac, P.; Obradovic, Z.; Smith, DK; Zhu, G.; Vucetic, S.; Brown, CJ; Lawson, JD; Dunker, AK Article
TROSY-based correlation and NOE spectroscopy for NMR structural studies of large proteins.
Methods in molecular biology (Clifton, N.J.), v. 278, 2004, p. 57-78
Zhu, G.; Xia, Y.; Lin, D.; Gao, X. Article
TROSY-based NMR experiments for the study of macromolecular dynamics and hydrogen bonding.
Methods in molecular biology (Clifton, N.J.), v. 278, 2004, p. 161-184
Zhu, G.; Xia, Y.; Lin, D.; Gao, X. Article
TROSY based correlation and NOE spectroscopy for NMR structural studies of large proteins
Biological NMR and its application / chapter 5, 57-78
Zhu, G.; Xia, Y.; Lin, D.; Gao, X. Book chapter
TROSY-Based NMR Experiments for the Study of Macromolecular Dynamics and Hydrogen Bonding
Protein NMR Techniques / Edited by A. Kristina Downing. Totowa, N.J.: Humana Press, c2004, p.161-184
Zhu, Guang; Xia, Youlin; Lin, Donghai; Gao, Xiaolian Book chapter

2003 5

Functional characterization of an amino-terminal region of HDAC4 that possesses MEF2 binding and transcriptional repressive activity
Journal of biological chemistry, v. 278, (26), 2003, JUN, p. 23515-23521
Chan, Jonathan K.L.; Sun, Luguo; Yang, Xiangjiao; Zhu, Guang; Wu, Zhenguo Article
Improved amino acid flexibility parameters
Protein science, v. 12, (5), 2003, MAY, p. 1060-1072
Smith, DK; Radivojac, P.; Obradovic, Z.; Dunker, AK; Zhu, G. Article
Interaction between calcium-free calmodulin and IQ motif of neurogranin studied by nuclear magnetic resonance spectroscopy
Analytical biochemistry, v. 315, (2), 2003, APR 15, p. 175-182
Cui, YF; Wen, J.; Sze, KH; Man, D.; Lin, DH; Liu, ML; Zhu, G. Article
Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex
Journal of Biological Chemistry, v. 278, (26), June 2003, p. 23285-23294
Man, David; He, Wei; Sze, Kong Hung; Gong, Ke; Smith, David K.; Zhu, Guang; Ip, Nancy Yuk-Yu Article
Substrate-induced conformational changes in Escherichia coli arginyl-tRNA synthetase observed by F-19 NMR spectroscopy
FEBS letters, v. 547, (1-3), 2003, JUL 17, p. 197-200
Yao, YN; Zhang, QS; Yan, XZ; Zhu, G.; Wang, ED Article

2002 9

Clean SEA-HSQC: A method to map solvent exposed amides in large non-deuterated proteins with gradient-enhanced HSQC
Journal of biomolecular NMR, v. 23, (4), 2002, AUG, p. 317-322
Lin, DH; Sze, KH; Cui, YF; Zhu, G. Article
Investigation of the structural stability of the human acidic fibroblast growth factor by hydrogen-deuterium exchange
Biochemistry, v. 41, (51), 2002, DEC 24, p. 15350-15359
Chi, YH; Kumar, TKS; Kathir, KM; Lin, Donghai; Zhu, Guang; Chiu, IM; Yu, C. Article
Letter to the Editor: Complete ¹H, ¹⁵N and ¹³C assignments of the carboxyl terminal domain of the ciliary neurotrophic factor receptor (CNTFR)
Journal of Biomolecular NMR, v. 22, (1), January 2002, p. 95-96
Man, David; Xia, Youlin; Sze, Konghung; Smith, David Keith; He, Wei; Ip, Nancy Yuk-Yu; Zhu, Guang Article
Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro
FEBS Letters, v. 514, (2-3), March 2002, p. 214-218
He, Wei; Gong, Ke; Zhu, Guang; Smith, David Keith; Ip, Nancy Yuk-Yu Article
NMR Analysis of Bovine tRNA(Trp) - Conformation Dependence of Mg2+ Binding
Journal of Biological Chemistry, v. 277, (23), 2002, p. 20694-20701
Gong, Qingguo; Guo, Qing; Tong, Ka Lok; Zhu, Guang; Wong, Jeffrey Tsz Fei; Xue, Hong Article
Protein dynamics measurements by 3D HNCO based NMR experiments
Spectroscopy-an INTERNATIONAL journal, v. 16, (1), 2002, p. 1-13
Xia, YL; Sze, KH; Li, N.; Shaw, PC; Zhu, G. Article
Recognition by Tryptophanyl-tRNA Synthetases of Discriminator Bbase on tRNA(TrP) from Three Biological Domains
Journal of Biological Chemistry, v. 277, (16), 2002, p. 14343-14349
Guo, Qing; Gong, Qingguo; Tong, Ka Lok; Vestergaard, Bente; Costa, Annie B.; Desgres, Jean A.; Wong, Mansim; Grosjean, Henri J.; Zhu, Guang; Wong, Jeffrey Tsz Fei; Xue, Hong Article
Multidimensional NMR data processing
Chapter 17, Signal processing for magnetic resonance imaging and spectroscopy. Edited by Hong Yan, , Marcel Dekker, Inc, New York / pp. 509-543
Zhu, G. Book chapter
NMR analysis of bovine tRNATrp: conformational dependence of Mg2+ binding sites
The 19th tRNA Workshop, Shanghai, P.R. China
Gong, Qingguo; Guo, Qing; Zhu, Guang; Wong, Tze-Fei Jeffrey; Xue, Hong Conference paper

2001 3

3D H-aro-NOESY-CH3NH and C-aro-NOESY-CH3NH experiments for double labeled proteins
Journal of biomolecular NMR, v. 19, (4), 2001, APR, p. 355-360
Xia, YL; Man, D.; Zhu, G. Article
The dual effects of ethylene on the negative gravicurvature of arabidopsis inflorescence, an intriguing action model for the plant hormone ethylene
Chinese Science Bulletin, v. 46, (4), 2001, FEB, p. 279-283
Lu, BW; Pei, LK; Chan, WK; Zhang, H.; Zhu, G.; Li, JY; Li, N. Article
Multidimensional NMR Spectroscopic Signal Processing
Signal Processing for Magnetic Resonance Imaging and Spectroscopy (ed. Hong Yan), Marcel Dekker, Inc., New York, Basel / 509-543
Zhu, Guang; Hua, Yingbo Book chapter

2000 7

A J-multiplied HMQC (MJ-HMQC) experiment for measuring ³J_HNHα coupling constants
Journal of Magnetic Resonance, v. 146, (1), September 2000, p. 228-231
Xia, Youlin; Kong, Xiangming; Ip, Nancy Yuk-yu; Zhu, Guang Article
Cernuosides A and B, two sucrase inhibitors from Pulsatilla cernua
Journal of natural products, v. 63, (2), 2000, FEB, p. 276-278
Zhang, QW; Ye, WC; Yan, XZ; Zhu, G.; Che, CT; Zhao, SX Article
Determination of internucleotide (h)J(HN) couplings by the modified 2D J(NN)-correlated [N-15, H-1] TROSY
Journal of magnetic resonance, v. 147, (2), 2000, DEC, p. 357-360
Yan, XZ; Kong, XM; Xia, YL; Sze, KH; Zhu, G. Article
NMR studies of Bacillus subtilis tRNA(Trp) hyperexpressed in Escherichia coli - Assignment of imino proton signals and determination of thermal stability
Journal of Biological Chemistry, v. 275, (10), 2000, p. 6712-6716
Yan, Xianzhong; Xue, Hong; Liu, Hongzhi; Hang, Jun; Wong, Jeffrey Tsz Fei; Zhu, Guang Article
Protein dynamics measurements by TROSY-based NMR experiments
Journal of magnetic resonance, v. 143, (2), 2000, APR, p. 423-426
Zhu, G.; Xia, YL; Nicholson, LK; Sze, KH Article
Sensitivity enhancement of HCACO by using an HMQC magnetization transfer scheme
Journal of magnetic resonance, v. 143, (2), 2000, APR, p. 407-410
Xia, YL; Kong, XM; Smith, DK; Liu, Y.; Man, D.; Zhu, G. Article
Transverse relaxation optimized 3D and 4D N-15/N-15 separated NOESY experiments of N-15 labeled proteins
Journal of biomolecular NMR, v. 18, (3), 2000, NOV, p. 261-268
Xia, YL; Sze, KH; Zhu, G. Article

1999 4

2D and 3D TROSY-enhanced NOESY of N-15 labeled proteins
Journal of biomolecular NMR, v. 14, (4), 1999, AUG, p. 377-381
Zhu, G.; Xia, YL; Sze, KH; Yan, XZ Article
Gradient and sensitivity enhanced multiple-quantum coherence in heteronuclear multidimensional NMR experiments
Journal of biomolecular NMR, v. 14, (2), 1999, JUN, p. 133-140
Kong, XM; Sze, KH; Zhu, G. Article
Gradient and sensitivity enhancement of 2D TROSY with water flip-back, 3D NOESY-TROSY and TOCSY-TROSY experiments
Journal of biomolecular NMR, v. 13, (1), 1999, JAN, p. 77-81
Zhu, G.; Kong, XM; Sze, KH Article
Phase sensitive 3D J-resolved HMBC experiment for spectral assignment and measurement of long-range heteronuclear coupling constants
Tetrahedron letters, v. 40, (30), 1999, JUL 23, p. 5587-5591
Sze, KH; Yan, XZ; Kong, XM; Che, CT; Zhu, G. Article

1998 4

Gradient- and sensitivity-enhanced heteronuclear multiple-quantum correlation spectroscopy
Journal of magnetic resonance, v. 135, (1), 1998, NOV, p. 232-235
Zhu, G.; Kong, XM; Sze, KH Article
Sensitivity enhancement in transverse relaxation optimized NMR spectroscopy
ANGEWANDTE chemie-international EDITION, v. 37, (20), 1998, p. 2859-2861
Zhu, GA; Kong, XM; Yan, XZ; Sze, KH Article
Spectral parameter estimation by an iterative quadratic maximum likelihood method
Journal of magnetic resonance, v. 135, (1), 1998, NOV, p. 37-43
Zhu, G.; Choy, WY; Sanctuary, BC Article
Suppression of diagonal peaks with singular value decomposition
Journal of magnetic resonance, v. 132, (1), 1998, MAY, p. 176-178
Zhu, G.; Choy, WY; Song, GQ; Sanctuary, BC Article

1997 3

Post-acquisition solvent suppression by singular-value decomposition
Journal of magnetic resonance, v. 124, (1), 1997, JAN, p. 286-289
Zhu, G.; Smith, D.; Hua, YB Article
Quantitative NMR signal analysis by an iterative quadratic maximum likelihood method
Chemical Physics Letters, v. 264, (3-4), 1997, JAN 10, p. 424-428
Zhu, G.; Hua, YB Article
Using neural network predicted secondary structure information in automatic protein NMR assignment
Journal of chemical information and computer sciences, v. 37, (6), 1997, NOV-DEC, p. 1086-1094
Choy, WY; Sanctuary, BC; Zhu, G. Article

1996 1

Application of a three-dimensional maximum-entropy method to processing sections of three-dimensional NMR spectra
Journal OF MAGNETIC RESONANCE Series B, v. 113, (3), 1996, DEC, p. 248-251
Zhu, G. Article

1995 1

NMRPIPE - A MULTIDIMENSIONAL SPECTRAL PROCESSING SYSTEM BASED ON UNIX PIPES
Journal of biomolecular NMR, v. 6, (3), 1995, NOV, p. 277-293
DELAGLIO, F.; GRZESIEK, S.; VUISTER, GW; ZHU, G.; PFEIFER, J.; BAX, A. Article

1994 4

Analysis of Sugar Puckers and Glycosidic Torsion Angles in a DNA G-Tetrad Structure by Heteronuclear Three-Bond J Couplings
J. Am. Chem Soc, v. 116, 1994, p. 8370-8371
Zhu, Guang; Live, David; Bax, Ad Article
Measurement of homo- and heteronuclear J couplings from quantitative J correlation
Methods in Enzymology, v. 239, 1994, p. 79-105
Bax, Ad; Vuister, Geerten W.; Grzesiek, Stephan; Delaglio, Frank; Wang, Andy C.; Tschudin, Rolf; Zhu, Guang Article
Measurement of two- and three-bond 1H-13C J couplings from quantitative heteronuclear J correlation for molecules with overlapping 1H resonances, Using T1 Noise Reduction
J. Magn. Reson Series A, v. 110, 1994, p. 257-261
Zhu, Guang; Renwick, Alistair; Bax, Ad Article
Stable Isotope Applications in Biomolecular Structure and Mechanisms
Stable Isotope Applications in Biomolecular Structure and Mechanisms, Edited by J. Trewhella, T.A. Cross and C. J. Unkefer, Los Alamos, New Mexico, 1994, 345 pages
Zhu, Guang; Live, David; Bax, Ad Article

1993 2

Discrete Fourier Transformation of NMR Signals. The Relationship between Sampling Delay Time and Spectral Baseline
J. Magn.Reson. Series A, v. 105, 1993, p. 219-222
Zhu, Guang; Torchia, Denis; Bax, Ad Article
Quantitative Measurement of Long-range 1H-13C J Couplings from Proton Detected HMBC Spectra.
J. Magn. Reson. Series A, v. 104, 1993, p. 353-357
Zhu, Guang; Bax, Ad Article

1992 2

Improved Linear Prediction of Truncated Damped Sinusoids Using modified Backward-Forward Linear Prediction
J.Magn.Reson, v. 100, 1992, p. 202-207
Zhu, Guang; Bax, Ad Article
Solution Structure of a Calmodulin-Target Peptide Complex by Multidimensional NMR
Science, v. 256, 1992, p. 632-638
Ikura, M.; Clore, G.M.; Gronenborn, A.M.; Zhu, Guang; Klee, C.B.; Bax, Ad Article

1991 3

Four-Dimensional Heteronuclear Triple Resonance NMR of Isotopically Enriched Proteins for Sequential assignment of Backbone atoms.
J. Magn. Reson, v. 91, 1991, p. 422-428
Kay, Lewis E.; Ikura, Mitsuhiko; Zhu, Guang; Bax, Ad Article
Removal of F1 Baseline Distortion and Optimization of Folding in Multi-Dimensional NMR Spectra
J. Magn. Reson, v. 91, 1991, p. 174-178
Bax, Ad; Ikura, Mitsuhiko; Kay, Lewis E.; Zhu, Guang Article
Two-dimensional Linear Prediction for Signals Truncated in Both Dimensions
J. Magn. Reson, v. 98, 1991, p. 192-199
Zhu, Guang; Bax, Ad Article

1990 1

Improved Linear Prediction for Truncated Signals of Known Phase.
J. Magn. Reson, v. 90, 1990, p. 405-410
Zhu, Guang; Bax, Ad Article

1988 1

Distribution of Energy in Polymers Due to Incident Electrons and Protons
Radiation Effec. and Defec. in Solids, v. 105, 1988, p. 303
Rustgi, M.L.; Pandey, L.N.; Wilson, J.W.; Long, S.A.T.; Zhu, Guang Article


Expand All Collapse All


Article 4

Crystal structure of parallel G-quadruplex formed by the two-repeat ALS-and FTD-related GGGGCC sequence
Nucleic Acids Research, v. 49, (10), June 2021, p. 5881-5890
Geng, Yanyan; Liu, Changdong; Cai, Qixu; Luo, Zhipu; Miao, Haitao; Shi, Xiao; Xu, Naining; Fung, Chun Po; Choy, To To; Yan, Bing; Li, Ning; Qian, Peiyuan; Zhou, Bo; Zhu, Guang
Isotopically Dimethyl Labeling-Based Quantitative Proteomic Analysis Of Phosphoproteomes Of Soybean Cultivars
Biomolecules, v. 11, (8), August 2021, article number 1218
Moradi, Atieh; Dai, Shuaijian; Wong,Oi Ying; Zhu, Guang; Yu, Fengchao; Lam, Hon-Ming; Wang, Zhiyong; Burlingame, Alma L.; Lin, Chengtao; Afsharifar, Alireza; Yu, Weichuan; Wang, Tingliang; Li, Ning
Quantitative evaluation and comparison of two prodrug-activating suicide gene therapies on oral squamous cell carcinoma
American Journal of Cancer Research, v. 11, (4), 15 April 2021, p. 1672-1682
Xu, Naining; Tian, Honglei; Fung, Chun Po; Lin, Yuntao; Zhu, Guang; Shen, Yuehong; Yang, Hongyu
Simultaneous Real-Time Three-Dimensional Localization And FRET Measurement Of Two Distinct Particles
Nano Letters, v. 21, (18), 7 September 2021, p. 7479-7485
Chen, Xingxiang; Liu, Teng; Qin, Xianan; Nguyen, Quang Quan; Lee, Chanwoo; Lee, Sang Kwon; Ren, Yaguang; Chu, Jun; Zhu, Guang; Yoon, Tae-Young; Park, Chan Young; Park, Hyo Keun


Expand All Collapse All


Article 2

An Essential and Cell-Cycle-Dependent ORC Dimerization Cycle Regulates Eukaryotic Chromosomal DNA Replication
Cell Reports, v. 30, (10), March 2020, article number E6, p. 3323-3338
Amin, Aftab; Wu, Rentian; Cheung, Man Hei; Scott, John F.; Wang, Ziyi; Zhou, Zijing; Liu, Changdong; Zhu, Guang; Wong, Chris Kong Chu; Yu, Zhiling; Liang, Chun
Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA
Nucleic Acids Research, v. 48, (19), November 2020, p. 11146-11161
Xu, Naining; You, Yingying; Liu, Changdong; Balasov, Maxim; Lun, Lee Tung; Geng, Yanyan; Fung, Chun Po; Miao, Haitao; Tian, Honglei; Choy, To To; Shi, Xiao; Fan, Zhuming; Zhou, Bo; Akhmetova, Katarina; Din, Rahman Ud; Yang, Hongyu; Hao, Quan; Qian, Peiyuan; Chesnokov, Igor; Zhu, Guang


Expand All Collapse All


Article 4

A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K⁺ solution
Chemical Science, v. 10, (1), January 2019, p. 218-226
Liu, Changdong; Zhou, Bo; Geng, Yanyan; Tam, Dick Yan; Feng, Rui; Miao, Haitao; Xu, Naining; Shi, Xiao; You, Yingying; Hong, Yuning; Tang, Benzhong; Lo, Pik Kwan; Kuryavyi, Vitaly; Zhu, Guang
G-quadruplex structures formed by human telomeric DNA and C9orf72 hexanucleotide repeats
Biophysical Reviews, v. 11, (3), June 2019, p. 389-393
Liu, Changdong; Geng, Yanyan; Miao, Haitao; Shi, Xiao; You, Yingying; Xu, Naining; Zhou, Bo; Zhu, Guang
The Biophysical Society of Hong Kong (BPHK): past, present, and future
Biophysical Reviews, v. 11, (3), June 2019, p. 259-261
Zhu, Guang
The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA
Nucleic Acids Research, v. 47, (10), June 2019, p. 5395-5404
Geng, Yanyan; Liu, Changdong; Zhou, Bo; Cai, Qixu; Miao, Haitao; Shi, Xiao; Xu, Naining; You, Yingying; Fung, Chun Po; Din, Rahman Ud; Zhu, Guang

Conference paper 1

A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K⁺ solution
International Conference on Cell Science & Molecular Biology 2019, Paris, France, 8-10 July 2019
Zhu, Guang


Expand All Collapse All


Article 3

Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites
Communications Chemistry, v. 1, (1), December 2018, article number 62
Beteck, Richard M.; Seldon, Ronnett; Coertzen, Dina; Van der watt, Mari?tte E.; Reader, Janette; Mackenzie, Jared S.; Lamprecht, Dirk A.; Abraham, Matthew; Eribez, Korina; Müller, Joachim; Feng, Rui; Zhu, Guang; De grano, Ruel Valerio Robles; Williams, Ian Duncan; Smit, Frans J.; Steyn, Adrie J. C.; Winzeler, Elizabeth A.; Hemphill, Andrew; Birkholtz, Lyn-Marie; Warner, Digby F.; N’da, David D.; Haynes, Richard K.
Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence
Scientific Reports, v. 8, (1), February 2018, article number 2366, p. 2366-2366
Zhou, Bo; Geng, Yanyan; Liu, Changdong; Miao, Haitao; Ren, Yaguang; Xu, Naining; Shi, Xiao; You, Yingying; Lee, Tung Lun; Zhu, Guang
Responsive Upconversion Nanoprobe for Monitoring and Inhibition of EBV-Associated Cancers via Targeting EBNA1
Nanoscale, v. 10, (33), 7 September 2018, p. 15632-15640
Zha, Shuai; Fung, Yan Ho; Chau, Ho-Fai; Ma, Ping’an; Lin, Jun; Wang, Jin; Chan, Lai Sheung; Zhu, Guang; Lung, Hong Lok; Wong, Ka-Leung

Conference paper 1

G-quadruplex Structures Formed by Human Telomeric DNA and C9orf72 Hexanucleotide Repeats
The 10th Asian Biophysics Association Symposium (ABA 2018) in conjunction with the Australian Society for Biophysics (ASB) Meeting, Melbourne, Australia, 2-6 December 2018
Zhu, Guang


Expand All Collapse All


Conference paper 3

Mechanistic study of human DNA replication proteins that regulate cell proliferation and differentiation
2nd International Cancer Study & Therapy Conference, Baltimore, USA, 20-22 February 2017
Zhu, Guang
Structure-functional Study of G-rich Oligonucleotides
2nd International Conference on Nucleic Acids, Molecular Biology & Molecular Medicine, Philadelphia, Pennsylvania, USA, 31 August - 1 September 2017
Zhu, Guang
Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD
Society of Chinese Bioscientists in America the 16th International Symposium (2017 SCBA) 全球华人生物学家大会暨 第十六届美洲华人生物科学学会学术研讨会, Hangzhou, China, 29 Jun - 3 Jul 2017
Zhou, Bo; Liu, Changdong; Geng, Yanyan; Zhu, Guang


Expand All Collapse All


Conference paper 3

Mechanistic Study of Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Mediated Latent DNA replication in Human Cells
2nd World Congress on Cancer and Prevention Methods, Furama RiverFront, Singapore, 7-9 November 2016
Zhu, Guang
Mechanistic Study of Epstein-Barr Virus Nuclear Antigen 1(EBNA1) Mediated DNA Replication in Human Cells
BIT's 14th Annual Congress of International Drug Discovery Science and Technology-South Korea 2016 (IDDST-South Korea 2016), Gyeonggi, South Korea, 16-18 June 2016
Zhu, Guang
与ALS/FTD相关联的C9orf72六核苷酸重复扩增所形成G-四链体DNA的拓扑结构
第十九届全国波谱学学术会 The 19th Chinese National Magnetic Resonance Conference, Lan Zhou, China, 17-20 August 2016
周波; 刘长东; 耿艳艳; 朱广


Expand All Collapse All


Article 3

Development of stapled helical peptides to perturb the Cdt1-Mcm6 interaction
Journal of Peptide Science, v. 21, (7), July 2015, p. 593-598
Lee, Jonghan Peter; Liu, Changdong; Li, Tianlu; Zhu, Guang; Li, Xuechen
Quadruplex Nucleic Acid Structure Determination by Solution NMR
Chinese Journal of Magnetic Resonance=波谱学杂志, v. 32, (2), June 2015, p. 150-162
Liu, Changdong; Zhu, Guang
Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD
Scientific Reports, v. 5, November 2015, article number 16673
Zhou, Bo; Liu, Changdong; Geng, Yanyan; Zhu, Guang

Conference paper 4

Mechanistic Study of Human DNA Replication Initiation and Relating Diseases
BIT's 6th Annual World Gene Convention - 2015, Qingdao, China, 13-15 November 2015
Zhu, Guang
Mechanistic study of human proteins that regulate cell proliferation and differentiation
World congress on Cancer and Prevention Methods, Dubai, UAE, 27-29 August 2015
Zhu, Guang
Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation
9th Asian Biophysics Association Symposium, Hangzhou, China, 9-12 May 2015
Zhu, Guang
Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad
The 22nd Symposium on Chemistry Postgraduate Research in Hong Kong, Hong Kong Baptist University, Hong Kong, 18 April 2015
Sun, Yueru; Yin, Shuhui; Feng, Yitao; Li, Jie; Zhou, Jiahai; Liu, Changdong; Zhu, Guang; Guo, Zhihong


Expand All Collapse All


Article 1

Molecular basis of the general base catalysis of an α/β- hydrolase catalytic triad
Journal of Biological Chemistry, v. 289, (22), May 2014, p. 15867-15879
Sun, Yueru; Yin, Shuhui; Feng, Yitao; Li, Jie; Zhou, Jiahai; Liu, Changdong; Zhu, Guang; Guo, Zhihong

Conference paper 3

Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation
The 4th World Congress on Cancer Science & Therapy, Chicago, USA, 20-22 October 2014
Zhu, Guang
Molecular Basis of the General Base Catalysis of an α/β-Hydrolase Catalytic Triad
The 2nd South China Structural Biology Symposium, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, 5-7 December 2014
Sun, Yueru; Yin, Shuhui; Feng, Yitao; Li, Jie; Zhou, Jiahai; Liu, Changdong; Zhu, Guang; Guo, Zhihong
Structure-functional study of human pre-replication complex
Chinese NMR society, Hanzhou, China, 14-16 October 2014
Zhu, Guang


Expand All Collapse All


Conference paper 4

Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation
The 12th Conference of the Asian Crystallographic Association, The Hong Kong University of Science and Technology, Hong Kong, 7-10 December 2013
Zhu, Guang
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
The 8th symposium of Asian Biophysics Association, Jeju Island, Korea, 26 - 29 May 2013
Zhu, Guang
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
BIT's Biopharmaceutical Summit-2013, Frankfurt, Germany, 7 - 8 August 2013
Zhou, Bo; Liu, Changdong; Geng, Yanyan; Zhu, Guang
The Chair-type Structure of the Intramolecular Human Telomeric G-quadruplex
BCEIA 2013 - The 15th Beijing Conference and Exhibition on Instrumental Analysis, Beijing, China, 23-26 October 2013
Liu, Changdong; Zhou, Bo; Feng, Rui; Zhu, Guang


Expand All Collapse All


Article 5

Dynamic Nuclear Polarization: New Methodology and Applications
Topics in Current Chemistry, v. 326, 2012, p. 215-242
Sze, Kong Hung; Wu, Qinglin; Tse, Ho Sum; Zhu, Guang
NMR of Proteins and Small Biomolecules Preface
Topics in Current Chemistry, v. 326, 2012, p. IX-X
Zhu, Guang
Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode
Journal of biological chemistry, v. 287, (31), July 2012, p. 26104-26114
Chen, Lihong; Liu, Changdong; Ko, Frankie Chi Fat; Xu, Naining; Ng, Irene Oi-Lin; Yam, Judy Wai Ping; Zhu, Guang
Structural basis for homeodomain recognition by the cell-cycle regulator Geminin
Proceedings of the National Academy of Sciences of the United States of America, v. 109, (23), June 2012, p. 8931-8936
Zhou, Bo; Liu, Changdong; Xu, Zhiwen; Zhu, Guang
Structural insights into the Cdt1-mediated MCM2-7 chromatin loading
Nucleic Acids Research, v. 40, (7), April 2012, p. 3208-3217
Liu, Changdong; Wu, Rentian; Zhou, Bo; Wang, Jiafeng; Wei, Zhun; Tye, Bik Kwoon; Liang, Chun; Zhu, Guang

Conference paper 3

Crowding effect on calmodulin bakcbone dynamics
The 20th Symposium on Chemistry Postgraduate Research in Hong Kong, The Chinese University of Hong Kong, 27 April 2013
Feng, Yitao; Liu, Changdong; Wu, Qinglin; Zhu, Guang; Guo, Zhihong
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
Joint Scientific Meeting of Hong Kong Society of neurosciences and the Biophysical Society of Hong Kong, Hong Kong, June 2012
Zhu, Guang
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
BIT's 3rd Annual World Congress of Biomarkers - 2012, GuangZhou, China, 2- 4 Dec 2012
Zhu, Guang


Expand All Collapse All


Article 2

¹H, ¹⁵N and ¹³C chemical shift assignments of the SH2 domain of human tensin2 (TENC1)
Biomolecular NMR Assignments, v. 5, (2), October 2011, p. 211-214
Chen, Lihong; Liu, Changdong; Rui, Feng; Zhu, Guang
1H, 15N chemical shift assignments of the imino groups in the base pairs of Escherichia coli tRNALeu (CAG)
Biomolecular NMR assignments, v. 5, (1), April 2011, p. 71-74
Hao, Zhan-Xi; Feng, Rui; Wang, En-Duo; Zhu, Guang

Book 1

NMR of Proteins or Small Biomolecules, Advance Topics in Chemistry
NMR of Proteins or Small Biomolecules, Advance Topics in Chemistry / v. 326, 2011, Nov
Zhu, Guang

Book chapter 1

Recent development in DMP(chapter 8), Advance Topics in Chemistry
Recent development in DMP(chapter 8), Advance Topics in Chemistry, / Nov.30
Sze, Konghong; Wu, Qinglin; Zhu, Guang

Conference paper 2

Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6
7th Asian Biophysics Association (ABA) Symposium & Annual Meeting of the Indian Biophysical Society (IBS), New Delhi, India, 30 January - 2 February 2011
Wei, Zhun; Liu, Changdong; Xu, Naining; Zhou, Bo; Zhu, Guang
Characterization and Structure Determination of the Cdt1 Binding Domain of Human Minichromosome Maintenance (Mcm) 6
Protein & Peptide Conference, March 23-25, 2011 in Beijing, China
Zhu, Guang


Expand All Collapse All


Article 5

¹H, ¹⁵N and ¹³C chemical shift assignments of the Cdt1 binding domain of human Mcm6
Biomolecular NMR Assignments, v. 4, (2), October 2010, p. 231-233
Liu, Changdong; Wei, Zhun; Zhu, Guang
Characterization and structure determination of the cdt1 binding domain of human minichromosome maintenance (Mcm) 6
Journal of Biological Chemistry, v. 285, (17), April 2010, p. 12469-12473
Wei, Zhun; Liu, Changdong; Wu, Xing; Xu, Naining; Zhou, Bo; Liang, Chun; Zhu, Guang
Solution structure of the dimerization domain of ribosomal protein P2 provides insights for the structural organization of eukaryotic stalk
Nucleic acids research, v. 38, (15), 2010, AUG, p. 5206-5216
Lee, Ka-Ming; Yu, Conny Wing-Heng; Chan, Denise So-Bik; Chiu, Teddy Yu-Hin; Zhu, Guang; Sze, Kong-Hung; Shaw, Pang-Chui; Wong, Kam-Bo
Studying base pair open-close kinetics of tRNA^Leu by TROSY-based proton exchange NMR spectroscopy
FEBS Letters, v. 584, (21), November 2010, p. 4449-4452
Hao, Zhan Xi; Tan, Min; Liu, Changdong; Feng, Rui; Wang, En Duo; Zhu, Guang
The interacting domains of hCdt1 and hMcm6 involved in the chromatin loading of the MCM complex in human cells
Cell Cycle, v. 9, (24), 2010, p. 4848-4857
Zhang, Jing; Yu, Lan; Wu, Xing; Zou, Lan; Sou, K.K.L.; Wei, Zhun; Cheng, Xue; Zhu, Guang; Liang, Chun

Conference paper 2

Characterization and structural determination of the Cdt1 binding domain of human Mcm6
Joint Scientific meeting of Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, University of Hong Kong, Jun 7-9, 2010
Wei, Zhun; Liu, Changdong; Xu, Naining; Zhou, Bo; Zhu, Guang
Solution structure of the Cdt1 binding domain of human Mcm6
The 16th National Magnetic Resonance Conference of the CPS, Hainan, China, Nov 24-27, 2010
Liu, Changdong; Wei, Zhun; Xu, Naining; Zhou, Bo; Zhu, Guang


Expand All Collapse All


Article 1

The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome
Nucleic acids research, v. 37, (2), 2009, FEB, p. 602-610
Too, Priscilla Hiu-Mei; Ma, Meiji Kit-Wan; Mak, Amanda Nga-Sze; Wong, Yuen-Ting; Tung, Christine Kit-Ching; Zhu, Guang; Au, Shannon Wing-Ngor; Wong, Kam-Bo; Shaw, Pang-Chui

Conference paper 1

Identification of the functional domains involved in the interaction between human Cdt1 and Mcm6
The Cold Spring Harbor Lab “Eukaryotic DNA Replication & Genome Maintenance” Meeting, Cold Spring Harbor Lab, N.Y., USA, 9/2009
Zhang, Jingjing; Wu, Xing; Yu, Lan; Wei, Zhun; Zou, Lan; Zhu, Guang; Liang, Chun


Expand All Collapse All


Article 3

MH1 domain of SMAD4 binds N-terminal residues of the homeodomain of Hoxc9
Biochimica et Biophysica Acta - Proteins and Proteomics, v. 1784, (5), 2008, MAY, p. 747-752
Zhou, Bo; Chen, Lihong; Wu, Xing; Wang, Jing; Yin, Yinliang; Zhu, Guang
SET8 plays a role in controlling G(1)/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail
Cell cycle, v. 7, (10), 2008, MAY 15, p. 1423-1432
Yin, Yinliang; Yu, Vivian C.; Zhu, Guang; Chang, Donald C.
TROSY-based NMR experiments for NMR studies of large biomolecules
Progress in nuclear magnetic resonance spectroscopy, v. 52, (1), 2008, JAN 30, p. 49-68
Zhu, Guang; Yao, Xuejun


Expand All Collapse All


Article 1

Interaction between trichosanthin, a ribosome inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses
Nucleic acids research, v. 35, (5), 2007, p. 1660-1672
Chan, Denise S.B.; Chu, Lai-On; Lee, Ka-Ming; Too, Priscilla H.M.; Ma, Kit-Wan; Sze, Kong-Hung; Zhu, Guang; Shaw, Pang-Chui; Wong, Kam-Bo


Expand All Collapse All


Article 2

Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation
Molecular and cellular biology, v. 25, (9), 2005, MAY, p. 3575-3582
Ma, Kewei; Chan, Jonathan K.L.; Zhu, Guang; Wu, Zhenguo
SET8 recognizes the sequence RHRK²⁰VLRDN within the N terminus of histone H4 and mono-methylates lysine 20
Journal of Biological Chemistry, v. 280, (3)4, August 2005, p. 30025-30031
Yin, Yinliang; Liu, Changdong; Tsai, Sau Na; Zhou, Bo; Ngai, Sai Ming; Zhu, Guang


Expand All Collapse All


Article 6

(3,2)D GFT-NMR experiments for fast data collection from proteins
Journal of biomolecular NMR, v. 29, (4), 2004, AUG, p. 467-476
Xia, YL; Zhu, G.; Veeraraghavan, S.; Gao, XL
Elucidation of the solution conformations of loloatin C by NMR Spectroscopy and molecular simulation
European journal of organic chemistry, v.2004, (1), JAN, 2004, p. 31-37
Chen, Heru; Haynes, Richard K.; Scherkenbeck, Jürgen; Sze, Kong H.; Zhu, Guang
Escherichia coli tRNA₄^Arg(UCU) induces a constrained conformation of the crucial Ω-loop of arginyl-tRNA synthetase
Biochemical and biophysical research communications, v. 313, (1), 2004, JAN 2, p. 129-134
Yao, Yong-Neng; Zhang, Qing-Shuo; Yan, Xian-Zhong; Zhu, Guang; Wang, En-Duo
Protein flexibility and intrinsic disorder
Protein science, v. 13, (1), 2004, JAN, p. 71-80
Radivojac, P.; Obradovic, Z.; Smith, DK; Zhu, G.; Vucetic, S.; Brown, CJ; Lawson, JD; Dunker, AK
TROSY-based correlation and NOE spectroscopy for NMR structural studies of large proteins.
Methods in molecular biology (Clifton, N.J.), v. 278, 2004, p. 57-78
Zhu, G.; Xia, Y.; Lin, D.; Gao, X.
TROSY-based NMR experiments for the study of macromolecular dynamics and hydrogen bonding.
Methods in molecular biology (Clifton, N.J.), v. 278, 2004, p. 161-184
Zhu, G.; Xia, Y.; Lin, D.; Gao, X.

Book chapter 2

TROSY based correlation and NOE spectroscopy for NMR structural studies of large proteins
Biological NMR and its application / chapter 5, 57-78
Zhu, G.; Xia, Y.; Lin, D.; Gao, X.
TROSY-Based NMR Experiments for the Study of Macromolecular Dynamics and Hydrogen Bonding
Protein NMR Techniques / Edited by A. Kristina Downing. Totowa, N.J.: Humana Press, c2004, p.161-184
Zhu, Guang; Xia, Youlin; Lin, Donghai; Gao, Xiaolian


Expand All Collapse All


Article 5

Functional characterization of an amino-terminal region of HDAC4 that possesses MEF2 binding and transcriptional repressive activity
Journal of biological chemistry, v. 278, (26), 2003, JUN, p. 23515-23521
Chan, Jonathan K.L.; Sun, Luguo; Yang, Xiangjiao; Zhu, Guang; Wu, Zhenguo
Improved amino acid flexibility parameters
Protein science, v. 12, (5), 2003, MAY, p. 1060-1072
Smith, DK; Radivojac, P.; Obradovic, Z.; Dunker, AK; Zhu, G.
Interaction between calcium-free calmodulin and IQ motif of neurogranin studied by nuclear magnetic resonance spectroscopy
Analytical biochemistry, v. 315, (2), 2003, APR 15, p. 175-182
Cui, YF; Wen, J.; Sze, KH; Man, D.; Lin, DH; Liu, ML; Zhu, G.
Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex
Journal of Biological Chemistry, v. 278, (26), June 2003, p. 23285-23294
Man, David; He, Wei; Sze, Kong Hung; Gong, Ke; Smith, David K.; Zhu, Guang; Ip, Nancy Yuk-Yu
Substrate-induced conformational changes in Escherichia coli arginyl-tRNA synthetase observed by F-19 NMR spectroscopy
FEBS letters, v. 547, (1-3), 2003, JUL 17, p. 197-200
Yao, YN; Zhang, QS; Yan, XZ; Zhu, G.; Wang, ED


Expand All Collapse All


Article 7

Clean SEA-HSQC: A method to map solvent exposed amides in large non-deuterated proteins with gradient-enhanced HSQC
Journal of biomolecular NMR, v. 23, (4), 2002, AUG, p. 317-322
Lin, DH; Sze, KH; Cui, YF; Zhu, G.
Investigation of the structural stability of the human acidic fibroblast growth factor by hydrogen-deuterium exchange
Biochemistry, v. 41, (51), 2002, DEC 24, p. 15350-15359
Chi, YH; Kumar, TKS; Kathir, KM; Lin, Donghai; Zhu, Guang; Chiu, IM; Yu, C.
Letter to the Editor: Complete ¹H, ¹⁵N and ¹³C assignments of the carboxyl terminal domain of the ciliary neurotrophic factor receptor (CNTFR)
Journal of Biomolecular NMR, v. 22, (1), January 2002, p. 95-96
Man, David; Xia, Youlin; Sze, Konghung; Smith, David Keith; He, Wei; Ip, Nancy Yuk-Yu; Zhu, Guang
Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro
FEBS Letters, v. 514, (2-3), March 2002, p. 214-218
He, Wei; Gong, Ke; Zhu, Guang; Smith, David Keith; Ip, Nancy Yuk-Yu
NMR Analysis of Bovine tRNA(Trp) - Conformation Dependence of Mg2+ Binding
Journal of Biological Chemistry, v. 277, (23), 2002, p. 20694-20701
Gong, Qingguo; Guo, Qing; Tong, Ka Lok; Zhu, Guang; Wong, Jeffrey Tsz Fei; Xue, Hong
Protein dynamics measurements by 3D HNCO based NMR experiments
Spectroscopy-an INTERNATIONAL journal, v. 16, (1), 2002, p. 1-13
Xia, YL; Sze, KH; Li, N.; Shaw, PC; Zhu, G.
Recognition by Tryptophanyl-tRNA Synthetases of Discriminator Bbase on tRNA(TrP) from Three Biological Domains
Journal of Biological Chemistry, v. 277, (16), 2002, p. 14343-14349
Guo, Qing; Gong, Qingguo; Tong, Ka Lok; Vestergaard, Bente; Costa, Annie B.; Desgres, Jean A.; Wong, Mansim; Grosjean, Henri J.; Zhu, Guang; Wong, Jeffrey Tsz Fei; Xue, Hong

Book chapter 1

Multidimensional NMR data processing
Chapter 17, Signal processing for magnetic resonance imaging and spectroscopy. Edited by Hong Yan, , Marcel Dekker, Inc, New York / pp. 509-543
Zhu, G.

Conference paper 1

NMR analysis of bovine tRNATrp: conformational dependence of Mg2+ binding sites
The 19th tRNA Workshop, Shanghai, P.R. China
Gong, Qingguo; Guo, Qing; Zhu, Guang; Wong, Tze-Fei Jeffrey; Xue, Hong


Expand All Collapse All


Article 2

3D H-aro-NOESY-CH3NH and C-aro-NOESY-CH3NH experiments for double labeled proteins
Journal of biomolecular NMR, v. 19, (4), 2001, APR, p. 355-360
Xia, YL; Man, D.; Zhu, G.
The dual effects of ethylene on the negative gravicurvature of arabidopsis inflorescence, an intriguing action model for the plant hormone ethylene
Chinese Science Bulletin, v. 46, (4), 2001, FEB, p. 279-283
Lu, BW; Pei, LK; Chan, WK; Zhang, H.; Zhu, G.; Li, JY; Li, N.

Book chapter 1

Multidimensional NMR Spectroscopic Signal Processing
Signal Processing for Magnetic Resonance Imaging and Spectroscopy (ed. Hong Yan), Marcel Dekker, Inc., New York, Basel / 509-543
Zhu, Guang; Hua, Yingbo


Expand All Collapse All


Article 7

A J-multiplied HMQC (MJ-HMQC) experiment for measuring ³J_HNHα coupling constants
Journal of Magnetic Resonance, v. 146, (1), September 2000, p. 228-231
Xia, Youlin; Kong, Xiangming; Ip, Nancy Yuk-yu; Zhu, Guang
Cernuosides A and B, two sucrase inhibitors from Pulsatilla cernua
Journal of natural products, v. 63, (2), 2000, FEB, p. 276-278
Zhang, QW; Ye, WC; Yan, XZ; Zhu, G.; Che, CT; Zhao, SX
Determination of internucleotide (h)J(HN) couplings by the modified 2D J(NN)-correlated [N-15, H-1] TROSY
Journal of magnetic resonance, v. 147, (2), 2000, DEC, p. 357-360
Yan, XZ; Kong, XM; Xia, YL; Sze, KH; Zhu, G.
NMR studies of Bacillus subtilis tRNA(Trp) hyperexpressed in Escherichia coli - Assignment of imino proton signals and determination of thermal stability
Journal of Biological Chemistry, v. 275, (10), 2000, p. 6712-6716
Yan, Xianzhong; Xue, Hong; Liu, Hongzhi; Hang, Jun; Wong, Jeffrey Tsz Fei; Zhu, Guang
Protein dynamics measurements by TROSY-based NMR experiments
Journal of magnetic resonance, v. 143, (2), 2000, APR, p. 423-426
Zhu, G.; Xia, YL; Nicholson, LK; Sze, KH
Sensitivity enhancement of HCACO by using an HMQC magnetization transfer scheme
Journal of magnetic resonance, v. 143, (2), 2000, APR, p. 407-410
Xia, YL; Kong, XM; Smith, DK; Liu, Y.; Man, D.; Zhu, G.
Transverse relaxation optimized 3D and 4D N-15/N-15 separated NOESY experiments of N-15 labeled proteins
Journal of biomolecular NMR, v. 18, (3), 2000, NOV, p. 261-268
Xia, YL; Sze, KH; Zhu, G.


Expand All Collapse All


Article 4

2D and 3D TROSY-enhanced NOESY of N-15 labeled proteins
Journal of biomolecular NMR, v. 14, (4), 1999, AUG, p. 377-381
Zhu, G.; Xia, YL; Sze, KH; Yan, XZ
Gradient and sensitivity enhanced multiple-quantum coherence in heteronuclear multidimensional NMR experiments
Journal of biomolecular NMR, v. 14, (2), 1999, JUN, p. 133-140
Kong, XM; Sze, KH; Zhu, G.
Gradient and sensitivity enhancement of 2D TROSY with water flip-back, 3D NOESY-TROSY and TOCSY-TROSY experiments
Journal of biomolecular NMR, v. 13, (1), 1999, JAN, p. 77-81
Zhu, G.; Kong, XM; Sze, KH
Phase sensitive 3D J-resolved HMBC experiment for spectral assignment and measurement of long-range heteronuclear coupling constants
Tetrahedron letters, v. 40, (30), 1999, JUL 23, p. 5587-5591
Sze, KH; Yan, XZ; Kong, XM; Che, CT; Zhu, G.


Expand All Collapse All


Article 4

Gradient- and sensitivity-enhanced heteronuclear multiple-quantum correlation spectroscopy
Journal of magnetic resonance, v. 135, (1), 1998, NOV, p. 232-235
Zhu, G.; Kong, XM; Sze, KH
Sensitivity enhancement in transverse relaxation optimized NMR spectroscopy
ANGEWANDTE chemie-international EDITION, v. 37, (20), 1998, p. 2859-2861
Zhu, GA; Kong, XM; Yan, XZ; Sze, KH
Spectral parameter estimation by an iterative quadratic maximum likelihood method
Journal of magnetic resonance, v. 135, (1), 1998, NOV, p. 37-43
Zhu, G.; Choy, WY; Sanctuary, BC
Suppression of diagonal peaks with singular value decomposition
Journal of magnetic resonance, v. 132, (1), 1998, MAY, p. 176-178
Zhu, G.; Choy, WY; Song, GQ; Sanctuary, BC


Expand All Collapse All


Article 3

Post-acquisition solvent suppression by singular-value decomposition
Journal of magnetic resonance, v. 124, (1), 1997, JAN, p. 286-289
Zhu, G.; Smith, D.; Hua, YB
Quantitative NMR signal analysis by an iterative quadratic maximum likelihood method
Chemical Physics Letters, v. 264, (3-4), 1997, JAN 10, p. 424-428
Zhu, G.; Hua, YB
Using neural network predicted secondary structure information in automatic protein NMR assignment
Journal of chemical information and computer sciences, v. 37, (6), 1997, NOV-DEC, p. 1086-1094
Choy, WY; Sanctuary, BC; Zhu, G.


Expand All Collapse All


Article 1

Application of a three-dimensional maximum-entropy method to processing sections of three-dimensional NMR spectra
Journal OF MAGNETIC RESONANCE Series B, v. 113, (3), 1996, DEC, p. 248-251
Zhu, G.


Expand All Collapse All


Article 1

NMRPIPE - A MULTIDIMENSIONAL SPECTRAL PROCESSING SYSTEM BASED ON UNIX PIPES
Journal of biomolecular NMR, v. 6, (3), 1995, NOV, p. 277-293
DELAGLIO, F.; GRZESIEK, S.; VUISTER, GW; ZHU, G.; PFEIFER, J.; BAX, A.


Expand All Collapse All


Article 4

Analysis of Sugar Puckers and Glycosidic Torsion Angles in a DNA G-Tetrad Structure by Heteronuclear Three-Bond J Couplings
J. Am. Chem Soc, v. 116, 1994, p. 8370-8371
Zhu, Guang; Live, David; Bax, Ad
Measurement of homo- and heteronuclear J couplings from quantitative J correlation
Methods in Enzymology, v. 239, 1994, p. 79-105
Bax, Ad; Vuister, Geerten W.; Grzesiek, Stephan; Delaglio, Frank; Wang, Andy C.; Tschudin, Rolf; Zhu, Guang
Measurement of two- and three-bond 1H-13C J couplings from quantitative heteronuclear J correlation for molecules with overlapping 1H resonances, Using T1 Noise Reduction
J. Magn. Reson Series A, v. 110, 1994, p. 257-261
Zhu, Guang; Renwick, Alistair; Bax, Ad
Stable Isotope Applications in Biomolecular Structure and Mechanisms
Stable Isotope Applications in Biomolecular Structure and Mechanisms, Edited by J. Trewhella, T.A. Cross and C. J. Unkefer, Los Alamos, New Mexico, 1994, 345 pages
Zhu, Guang; Live, David; Bax, Ad


Expand All Collapse All


Article 2

Discrete Fourier Transformation of NMR Signals. The Relationship between Sampling Delay Time and Spectral Baseline
J. Magn.Reson. Series A, v. 105, 1993, p. 219-222
Zhu, Guang; Torchia, Denis; Bax, Ad
Quantitative Measurement of Long-range 1H-13C J Couplings from Proton Detected HMBC Spectra.
J. Magn. Reson. Series A, v. 104, 1993, p. 353-357
Zhu, Guang; Bax, Ad


Expand All Collapse All


Article 2

Improved Linear Prediction of Truncated Damped Sinusoids Using modified Backward-Forward Linear Prediction
J.Magn.Reson, v. 100, 1992, p. 202-207
Zhu, Guang; Bax, Ad
Solution Structure of a Calmodulin-Target Peptide Complex by Multidimensional NMR
Science, v. 256, 1992, p. 632-638
Ikura, M.; Clore, G.M.; Gronenborn, A.M.; Zhu, Guang; Klee, C.B.; Bax, Ad


Expand All Collapse All


Article 3

Four-Dimensional Heteronuclear Triple Resonance NMR of Isotopically Enriched Proteins for Sequential assignment of Backbone atoms.
J. Magn. Reson, v. 91, 1991, p. 422-428
Kay, Lewis E.; Ikura, Mitsuhiko; Zhu, Guang; Bax, Ad
Removal of F1 Baseline Distortion and Optimization of Folding in Multi-Dimensional NMR Spectra
J. Magn. Reson, v. 91, 1991, p. 174-178
Bax, Ad; Ikura, Mitsuhiko; Kay, Lewis E.; Zhu, Guang
Two-dimensional Linear Prediction for Signals Truncated in Both Dimensions
J. Magn. Reson, v. 98, 1991, p. 192-199
Zhu, Guang; Bax, Ad


Expand All Collapse All


Article 1

Improved Linear Prediction for Truncated Signals of Known Phase.
J. Magn. Reson, v. 90, 1990, p. 405-410
Zhu, Guang; Bax, Ad


Expand All Collapse All


Article 1

Distribution of Energy in Polymers Due to Incident Electrons and Protons
Radiation Effec. and Defec. in Solids, v. 105, 1988, p. 303
Rustgi, M.L.; Pandey, L.N.; Wilson, J.W.; Long, S.A.T.; Zhu, Guang


Expand All Collapse All


2016 3

Mechanistic Study of Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Mediated Latent DNA replication in Human Cells
2nd World Congress on Cancer and Prevention Methods, Furama RiverFront, Singapore, 7-9 November 2016
Zhu, Guang Conference paper
Mechanistic Study of Epstein-Barr Virus Nuclear Antigen 1(EBNA1) Mediated DNA Replication in Human Cells
BIT's 14th Annual Congress of International Drug Discovery Science and Technology-South Korea 2016 (IDDST-South Korea 2016), Gyeonggi, South Korea, 16-18 June 2016
Zhu, Guang Conference paper
与ALS/FTD相关联的C9orf72六核苷酸重复扩增所形成G-四链体DNA的拓扑结构
第十九届全国波谱学学术会 The 19th Chinese National Magnetic Resonance Conference, Lan Zhou, China, 17-20 August 2016
周波; 刘长东; 耿艳艳; 朱广 Conference paper

2015 7

Development of stapled helical peptides to perturb the Cdt1-Mcm6 interaction
Journal of Peptide Science, v. 21, (7), July 2015, p. 593-598
Lee, Jonghan Peter; Liu, Changdong; Li, Tianlu; Zhu, Guang; Li, Xuechen Article
Quadruplex Nucleic Acid Structure Determination by Solution NMR
Chinese Journal of Magnetic Resonance=波谱学杂志, v. 32, (2), June 2015, p. 150-162
Liu, Changdong; Zhu, Guang Article
Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD
Scientific Reports, v. 5, November 2015, article number 16673
Zhou, Bo; Liu, Changdong; Geng, Yanyan; Zhu, Guang Article
Mechanistic Study of Human DNA Replication Initiation and Relating Diseases
BIT's 6th Annual World Gene Convention - 2015, Qingdao, China, 13-15 November 2015
Zhu, Guang Conference paper
Mechanistic study of human proteins that regulate cell proliferation and differentiation
World congress on Cancer and Prevention Methods, Dubai, UAE, 27-29 August 2015
Zhu, Guang Conference paper
Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation
9th Asian Biophysics Association Symposium, Hangzhou, China, 9-12 May 2015
Zhu, Guang Conference paper
Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad
The 22nd Symposium on Chemistry Postgraduate Research in Hong Kong, Hong Kong Baptist University, Hong Kong, 18 April 2015
Sun, Yueru; Yin, Shuhui; Feng, Yitao; Li, Jie; Zhou, Jiahai; Liu, Changdong; Zhu, Guang; Guo, Zhihong Conference paper

2014 4

Molecular basis of the general base catalysis of an α/β- hydrolase catalytic triad
Journal of Biological Chemistry, v. 289, (22), May 2014, p. 15867-15879
Sun, Yueru; Yin, Shuhui; Feng, Yitao; Li, Jie; Zhou, Jiahai; Liu, Changdong; Zhu, Guang; Guo, Zhihong Article
Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation
The 4th World Congress on Cancer Science & Therapy, Chicago, USA, 20-22 October 2014
Zhu, Guang Conference paper
Molecular Basis of the General Base Catalysis of an α/β-Hydrolase Catalytic Triad
The 2nd South China Structural Biology Symposium, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, 5-7 December 2014
Sun, Yueru; Yin, Shuhui; Feng, Yitao; Li, Jie; Zhou, Jiahai; Liu, Changdong; Zhu, Guang; Guo, Zhihong Conference paper
Structure-functional study of human pre-replication complex
Chinese NMR society, Hanzhou, China, 14-16 October 2014
Zhu, Guang Conference paper

2013 4

Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation
The 12th Conference of the Asian Crystallographic Association, The Hong Kong University of Science and Technology, Hong Kong, 7-10 December 2013
Zhu, Guang Conference paper
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
The 8th symposium of Asian Biophysics Association, Jeju Island, Korea, 26 - 29 May 2013
Zhu, Guang Conference paper
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
BIT's Biopharmaceutical Summit-2013, Frankfurt, Germany, 7 - 8 August 2013
Zhou, Bo; Liu, Changdong; Geng, Yanyan; Zhu, Guang Conference paper
The Chair-type Structure of the Intramolecular Human Telomeric G-quadruplex
BCEIA 2013 - The 15th Beijing Conference and Exhibition on Instrumental Analysis, Beijing, China, 23-26 October 2013
Liu, Changdong; Zhou, Bo; Feng, Rui; Zhu, Guang Conference paper

2012 8

Dynamic Nuclear Polarization: New Methodology and Applications
Topics in Current Chemistry, v. 326, 2012, p. 215-242
Sze, Kong Hung; Wu, Qinglin; Tse, Ho Sum; Zhu, Guang Article
NMR of Proteins and Small Biomolecules Preface
Topics in Current Chemistry, v. 326, 2012, p. IX-X
Zhu, Guang Article
Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode
Journal of biological chemistry, v. 287, (31), July 2012, p. 26104-26114
Chen, Lihong; Liu, Changdong; Ko, Frankie Chi Fat; Xu, Naining; Ng, Irene Oi-Lin; Yam, Judy Wai Ping; Zhu, Guang Article
Structural basis for homeodomain recognition by the cell-cycle regulator Geminin
Proceedings of the National Academy of Sciences of the United States of America, v. 109, (23), June 2012, p. 8931-8936
Zhou, Bo; Liu, Changdong; Xu, Zhiwen; Zhu, Guang Article
Structural insights into the Cdt1-mediated MCM2-7 chromatin loading
Nucleic Acids Research, v. 40, (7), April 2012, p. 3208-3217
Liu, Changdong; Wu, Rentian; Zhou, Bo; Wang, Jiafeng; Wei, Zhun; Tye, Bik Kwoon; Liang, Chun; Zhu, Guang Article
Crowding effect on calmodulin bakcbone dynamics
The 20th Symposium on Chemistry Postgraduate Research in Hong Kong, The Chinese University of Hong Kong, 27 April 2013
Feng, Yitao; Liu, Changdong; Wu, Qinglin; Zhu, Guang; Guo, Zhihong Conference paper
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
Joint Scientific Meeting of Hong Kong Society of neurosciences and the Biophysical Society of Hong Kong, Hong Kong, June 2012
Zhu, Guang Conference paper
Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation
BIT's 3rd Annual World Congress of Biomarkers - 2012, GuangZhou, China, 2- 4 Dec 2012
Zhu, Guang Conference paper

2011 6

¹H, ¹⁵N and ¹³C chemical shift assignments of the SH2 domain of human tensin2 (TENC1)
Biomolecular NMR Assignments, v. 5, (2), October 2011, p. 211-214
Chen, Lihong; Liu, Changdong; Rui, Feng; Zhu, Guang Article
1H, 15N chemical shift assignments of the imino groups in the base pairs of Escherichia coli tRNALeu (CAG)
Biomolecular NMR assignments, v. 5, (1), April 2011, p. 71-74
Hao, Zhan-Xi; Feng, Rui; Wang, En-Duo; Zhu, Guang Article
NMR of Proteins or Small Biomolecules, Advance Topics in Chemistry
NMR of Proteins or Small Biomolecules, Advance Topics in Chemistry / v. 326, 2011, Nov
Zhu, Guang Book
Recent development in DMP(chapter 8), Advance Topics in Chemistry
Recent development in DMP(chapter 8), Advance Topics in Chemistry, / Nov.30
Sze, Konghong; Wu, Qinglin; Zhu, Guang Book chapter
Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6
7th Asian Biophysics Association (ABA) Symposium & Annual Meeting of the Indian Biophysical Society (IBS), New Delhi, India, 30 January - 2 February 2011
Wei, Zhun; Liu, Changdong; Xu, Naining; Zhou, Bo; Zhu, Guang Conference paper
Characterization and Structure Determination of the Cdt1 Binding Domain of Human Minichromosome Maintenance (Mcm) 6
Protein & Peptide Conference, March 23-25, 2011 in Beijing, China
Zhu, Guang Conference paper

2010 7

¹H, ¹⁵N and ¹³C chemical shift assignments of the Cdt1 binding domain of human Mcm6
Biomolecular NMR Assignments, v. 4, (2), October 2010, p. 231-233
Liu, Changdong; Wei, Zhun; Zhu, Guang Article
Characterization and structure determination of the cdt1 binding domain of human minichromosome maintenance (Mcm) 6
Journal of Biological Chemistry, v. 285, (17), April 2010, p. 12469-12473
Wei, Zhun; Liu, Changdong; Wu, Xing; Xu, Naining; Zhou, Bo; Liang, Chun; Zhu, Guang Article
Solution structure of the dimerization domain of ribosomal protein P2 provides insights for the structural organization of eukaryotic stalk
Nucleic acids research, v. 38, (15), 2010, AUG, p. 5206-5216
Lee, Ka-Ming; Yu, Conny Wing-Heng; Chan, Denise So-Bik; Chiu, Teddy Yu-Hin; Zhu, Guang; Sze, Kong-Hung; Shaw, Pang-Chui; Wong, Kam-Bo Article
Studying base pair open-close kinetics of tRNA^Leu by TROSY-based proton exchange NMR spectroscopy
FEBS Letters, v. 584, (21), November 2010, p. 4449-4452
Hao, Zhan Xi; Tan, Min; Liu, Changdong; Feng, Rui; Wang, En Duo; Zhu, Guang Article
The interacting domains of hCdt1 and hMcm6 involved in the chromatin loading of the MCM complex in human cells
Cell Cycle, v. 9, (24), 2010, p. 4848-4857
Zhang, Jing; Yu, Lan; Wu, Xing; Zou, Lan; Sou, K.K.L.; Wei, Zhun; Cheng, Xue; Zhu, Guang; Liang, Chun Article
Characterization and structural determination of the Cdt1 binding domain of human Mcm6
Joint Scientific meeting of Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, University of Hong Kong, Jun 7-9, 2010
Wei, Zhun; Liu, Changdong; Xu, Naining; Zhou, Bo; Zhu, Guang Conference paper
Solution structure of the Cdt1 binding domain of human Mcm6
The 16th National Magnetic Resonance Conference of the CPS, Hainan, China, Nov 24-27, 2010
Liu, Changdong; Wei, Zhun; Xu, Naining; Zhou, Bo; Zhu, Guang Conference paper

2009 2

The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome
Nucleic acids research, v. 37, (2), 2009, FEB, p. 602-610
Too, Priscilla Hiu-Mei; Ma, Meiji Kit-Wan; Mak, Amanda Nga-Sze; Wong, Yuen-Ting; Tung, Christine Kit-Ching; Zhu, Guang; Au, Shannon Wing-Ngor; Wong, Kam-Bo; Shaw, Pang-Chui Article
Identification of the functional domains involved in the interaction between human Cdt1 and Mcm6
The Cold Spring Harbor Lab “Eukaryotic DNA Replication & Genome Maintenance” Meeting, Cold Spring Harbor Lab, N.Y., USA, 9/2009
Zhang, Jingjing; Wu, Xing; Yu, Lan; Wei, Zhun; Zou, Lan; Zhu, Guang; Liang, Chun Conference paper

2008 3

MH1 domain of SMAD4 binds N-terminal residues of the homeodomain of Hoxc9
Biochimica et Biophysica Acta - Proteins and Proteomics, v. 1784, (5), 2008, MAY, p. 747-752
Zhou, Bo; Chen, Lihong; Wu, Xing; Wang, Jing; Yin, Yinliang; Zhu, Guang Article
SET8 plays a role in controlling G(1)/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail
Cell cycle, v. 7, (10), 2008, MAY 15, p. 1423-1432
Yin, Yinliang; Yu, Vivian C.; Zhu, Guang; Chang, Donald C. Article
TROSY-based NMR experiments for NMR studies of large biomolecules
Progress in nuclear magnetic resonance spectroscopy, v. 52, (1), 2008, JAN 30, p. 49-68
Zhu, Guang; Yao, Xuejun Article

2007 1

Interaction between trichosanthin, a ribosome inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses
Nucleic acids research, v. 35, (5), 2007, p. 1660-1672
Chan, Denise S.B.; Chu, Lai-On; Lee, Ka-Ming; Too, Priscilla H.M.; Ma, Kit-Wan; Sze, Kong-Hung; Zhu, Guang; Shaw, Pang-Chui; Wong, Kam-Bo Article

2005 2

Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation
Molecular and cellular biology, v. 25, (9), 2005, MAY, p. 3575-3582
Ma, Kewei; Chan, Jonathan K.L.; Zhu, Guang; Wu, Zhenguo Article
SET8 recognizes the sequence RHRK²⁰VLRDN within the N terminus of histone H4 and mono-methylates lysine 20
Journal of Biological Chemistry, v. 280, (3)4, August 2005, p. 30025-30031
Yin, Yinliang; Liu, Changdong; Tsai, Sau Na; Zhou, Bo; Ngai, Sai Ming; Zhu, Guang Article

2004 8

(3,2)D GFT-NMR experiments for fast data collection from proteins
Journal of biomolecular NMR, v. 29, (4), 2004, AUG, p. 467-476
Xia, YL; Zhu, G.; Veeraraghavan, S.; Gao, XL Article
Elucidation of the solution conformations of loloatin C by NMR Spectroscopy and molecular simulation
European journal of organic chemistry, v.2004, (1), JAN, 2004, p. 31-37
Chen, Heru; Haynes, Richard K.; Scherkenbeck, Jürgen; Sze, Kong H.; Zhu, Guang Article
Escherichia coli tRNA₄^Arg(UCU) induces a constrained conformation of the crucial Ω-loop of arginyl-tRNA synthetase
Biochemical and biophysical research communications, v. 313, (1), 2004, JAN 2, p. 129-134
Yao, Yong-Neng; Zhang, Qing-Shuo; Yan, Xian-Zhong; Zhu, Guang; Wang, En-Duo Article
Protein flexibility and intrinsic disorder
Protein science, v. 13, (1), 2004, JAN, p. 71-80
Radivojac, P.; Obradovic, Z.; Smith, DK; Zhu, G.; Vucetic, S.; Brown, CJ; Lawson, JD; Dunker, AK Article
TROSY-based correlation and NOE spectroscopy for NMR structural studies of large proteins.
Methods in molecular biology (Clifton, N.J.), v. 278, 2004, p. 57-78
Zhu, G.; Xia, Y.; Lin, D.; Gao, X. Article
TROSY-based NMR experiments for the study of macromolecular dynamics and hydrogen bonding.
Methods in molecular biology (Clifton, N.J.), v. 278, 2004, p. 161-184
Zhu, G.; Xia, Y.; Lin, D.; Gao, X. Article
TROSY based correlation and NOE spectroscopy for NMR structural studies of large proteins
Biological NMR and its application / chapter 5, 57-78
Zhu, G.; Xia, Y.; Lin, D.; Gao, X. Book chapter
TROSY-Based NMR Experiments for the Study of Macromolecular Dynamics and Hydrogen Bonding
Protein NMR Techniques / Edited by A. Kristina Downing. Totowa, N.J.: Humana Press, c2004, p.161-184
Zhu, Guang; Xia, Youlin; Lin, Donghai; Gao, Xiaolian Book chapter

2003 5

Functional characterization of an amino-terminal region of HDAC4 that possesses MEF2 binding and transcriptional repressive activity
Journal of biological chemistry, v. 278, (26), 2003, JUN, p. 23515-23521
Chan, Jonathan K.L.; Sun, Luguo; Yang, Xiangjiao; Zhu, Guang; Wu, Zhenguo Article
Improved amino acid flexibility parameters
Protein science, v. 12, (5), 2003, MAY, p. 1060-1072
Smith, DK; Radivojac, P.; Obradovic, Z.; Dunker, AK; Zhu, G. Article
Interaction between calcium-free calmodulin and IQ motif of neurogranin studied by nuclear magnetic resonance spectroscopy
Analytical biochemistry, v. 315, (2), 2003, APR 15, p. 175-182
Cui, YF; Wen, J.; Sze, KH; Man, D.; Lin, DH; Liu, ML; Zhu, G. Article
Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex
Journal of Biological Chemistry, v. 278, (26), June 2003, p. 23285-23294
Man, David; He, Wei; Sze, Kong Hung; Gong, Ke; Smith, David K.; Zhu, Guang; Ip, Nancy Yuk-Yu Article
Substrate-induced conformational changes in Escherichia coli arginyl-tRNA synthetase observed by F-19 NMR spectroscopy
FEBS letters, v. 547, (1-3), 2003, JUL 17, p. 197-200
Yao, YN; Zhang, QS; Yan, XZ; Zhu, G.; Wang, ED Article

2002 9

Clean SEA-HSQC: A method to map solvent exposed amides in large non-deuterated proteins with gradient-enhanced HSQC
Journal of biomolecular NMR, v. 23, (4), 2002, AUG, p. 317-322
Lin, DH; Sze, KH; Cui, YF; Zhu, G. Article
Investigation of the structural stability of the human acidic fibroblast growth factor by hydrogen-deuterium exchange
Biochemistry, v. 41, (51), 2002, DEC 24, p. 15350-15359
Chi, YH; Kumar, TKS; Kathir, KM; Lin, Donghai; Zhu, Guang; Chiu, IM; Yu, C. Article
Letter to the Editor: Complete ¹H, ¹⁵N and ¹³C assignments of the carboxyl terminal domain of the ciliary neurotrophic factor receptor (CNTFR)
Journal of Biomolecular NMR, v. 22, (1), January 2002, p. 95-96
Man, David; Xia, Youlin; Sze, Konghung; Smith, David Keith; He, Wei; Ip, Nancy Yuk-Yu; Zhu, Guang Article
Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro
FEBS Letters, v. 514, (2-3), March 2002, p. 214-218
He, Wei; Gong, Ke; Zhu, Guang; Smith, David Keith; Ip, Nancy Yuk-Yu Article
NMR Analysis of Bovine tRNA(Trp) - Conformation Dependence of Mg2+ Binding
Journal of Biological Chemistry, v. 277, (23), 2002, p. 20694-20701
Gong, Qingguo; Guo, Qing; Tong, Ka Lok; Zhu, Guang; Wong, Jeffrey Tsz Fei; Xue, Hong Article
Protein dynamics measurements by 3D HNCO based NMR experiments
Spectroscopy-an INTERNATIONAL journal, v. 16, (1), 2002, p. 1-13
Xia, YL; Sze, KH; Li, N.; Shaw, PC; Zhu, G. Article
Recognition by Tryptophanyl-tRNA Synthetases of Discriminator Bbase on tRNA(TrP) from Three Biological Domains
Journal of Biological Chemistry, v. 277, (16), 2002, p. 14343-14349
Guo, Qing; Gong, Qingguo; Tong, Ka Lok; Vestergaard, Bente; Costa, Annie B.; Desgres, Jean A.; Wong, Mansim; Grosjean, Henri J.; Zhu, Guang; Wong, Jeffrey Tsz Fei; Xue, Hong Article
Multidimensional NMR data processing
Chapter 17, Signal processing for magnetic resonance imaging and spectroscopy. Edited by Hong Yan, , Marcel Dekker, Inc, New York / pp. 509-543
Zhu, G. Book chapter
NMR analysis of bovine tRNATrp: conformational dependence of Mg2+ binding sites
The 19th tRNA Workshop, Shanghai, P.R. China
Gong, Qingguo; Guo, Qing; Zhu, Guang; Wong, Tze-Fei Jeffrey; Xue, Hong Conference paper

2001 3

3D H-aro-NOESY-CH3NH and C-aro-NOESY-CH3NH experiments for double labeled proteins
Journal of biomolecular NMR, v. 19, (4), 2001, APR, p. 355-360
Xia, YL; Man, D.; Zhu, G. Article
The dual effects of ethylene on the negative gravicurvature of arabidopsis inflorescence, an intriguing action model for the plant hormone ethylene
Chinese Science Bulletin, v. 46, (4), 2001, FEB, p. 279-283
Lu, BW; Pei, LK; Chan, WK; Zhang, H.; Zhu, G.; Li, JY; Li, N. Article
Multidimensional NMR Spectroscopic Signal Processing
Signal Processing for Magnetic Resonance Imaging and Spectroscopy (ed. Hong Yan), Marcel Dekker, Inc., New York, Basel / 509-543
Zhu, Guang; Hua, Yingbo Book chapter

2000 7

A J-multiplied HMQC (MJ-HMQC) experiment for measuring ³J_HNHα coupling constants
Journal of Magnetic Resonance, v. 146, (1), September 2000, p. 228-231
Xia, Youlin; Kong, Xiangming; Ip, Nancy Yuk-yu; Zhu, Guang Article
Cernuosides A and B, two sucrase inhibitors from Pulsatilla cernua
Journal of natural products, v. 63, (2), 2000, FEB, p. 276-278
Zhang, QW; Ye, WC; Yan, XZ; Zhu, G.; Che, CT; Zhao, SX Article
Determination of internucleotide (h)J(HN) couplings by the modified 2D J(NN)-correlated [N-15, H-1] TROSY
Journal of magnetic resonance, v. 147, (2), 2000, DEC, p. 357-360
Yan, XZ; Kong, XM; Xia, YL; Sze, KH; Zhu, G. Article
NMR studies of Bacillus subtilis tRNA(Trp) hyperexpressed in Escherichia coli - Assignment of imino proton signals and determination of thermal stability
Journal of Biological Chemistry, v. 275, (10), 2000, p. 6712-6716
Yan, Xianzhong; Xue, Hong; Liu, Hongzhi; Hang, Jun; Wong, Jeffrey Tsz Fei; Zhu, Guang Article
Protein dynamics measurements by TROSY-based NMR experiments
Journal of magnetic resonance, v. 143, (2), 2000, APR, p. 423-426
Zhu, G.; Xia, YL; Nicholson, LK; Sze, KH Article
Sensitivity enhancement of HCACO by using an HMQC magnetization transfer scheme
Journal of magnetic resonance, v. 143, (2), 2000, APR, p. 407-410
Xia, YL; Kong, XM; Smith, DK; Liu, Y.; Man, D.; Zhu, G. Article
Transverse relaxation optimized 3D and 4D N-15/N-15 separated NOESY experiments of N-15 labeled proteins
Journal of biomolecular NMR, v. 18, (3), 2000, NOV, p. 261-268
Xia, YL; Sze, KH; Zhu, G. Article

1999 4

2D and 3D TROSY-enhanced NOESY of N-15 labeled proteins
Journal of biomolecular NMR, v. 14, (4), 1999, AUG, p. 377-381
Zhu, G.; Xia, YL; Sze, KH; Yan, XZ Article
Gradient and sensitivity enhanced multiple-quantum coherence in heteronuclear multidimensional NMR experiments
Journal of biomolecular NMR, v. 14, (2), 1999, JUN, p. 133-140
Kong, XM; Sze, KH; Zhu, G. Article
Gradient and sensitivity enhancement of 2D TROSY with water flip-back, 3D NOESY-TROSY and TOCSY-TROSY experiments
Journal of biomolecular NMR, v. 13, (1), 1999, JAN, p. 77-81
Zhu, G.; Kong, XM; Sze, KH Article
Phase sensitive 3D J-resolved HMBC experiment for spectral assignment and measurement of long-range heteronuclear coupling constants
Tetrahedron letters, v. 40, (30), 1999, JUL 23, p. 5587-5591
Sze, KH; Yan, XZ; Kong, XM; Che, CT; Zhu, G. Article

1998 4

Gradient- and sensitivity-enhanced heteronuclear multiple-quantum correlation spectroscopy
Journal of magnetic resonance, v. 135, (1), 1998, NOV, p. 232-235
Zhu, G.; Kong, XM; Sze, KH Article
Sensitivity enhancement in transverse relaxation optimized NMR spectroscopy
ANGEWANDTE chemie-international EDITION, v. 37, (20), 1998, p. 2859-2861
Zhu, GA; Kong, XM; Yan, XZ; Sze, KH Article
Spectral parameter estimation by an iterative quadratic maximum likelihood method
Journal of magnetic resonance, v. 135, (1), 1998, NOV, p. 37-43
Zhu, G.; Choy, WY; Sanctuary, BC Article
Suppression of diagonal peaks with singular value decomposition
Journal of magnetic resonance, v. 132, (1), 1998, MAY, p. 176-178
Zhu, G.; Choy, WY; Song, GQ; Sanctuary, BC Article

1997 3

Post-acquisition solvent suppression by singular-value decomposition
Journal of magnetic resonance, v. 124, (1), 1997, JAN, p. 286-289
Zhu, G.; Smith, D.; Hua, YB Article
Quantitative NMR signal analysis by an iterative quadratic maximum likelihood method
Chemical Physics Letters, v. 264, (3-4), 1997, JAN 10, p. 424-428
Zhu, G.; Hua, YB Article
Using neural network predicted secondary structure information in automatic protein NMR assignment
Journal of chemical information and computer sciences, v. 37, (6), 1997, NOV-DEC, p. 1086-1094
Choy, WY; Sanctuary, BC; Zhu, G. Article

1996 1

Application of a three-dimensional maximum-entropy method to processing sections of three-dimensional NMR spectra
Journal OF MAGNETIC RESONANCE Series B, v. 113, (3), 1996, DEC, p. 248-251
Zhu, G. Article

1995 1

NMRPIPE - A MULTIDIMENSIONAL SPECTRAL PROCESSING SYSTEM BASED ON UNIX PIPES
Journal of biomolecular NMR, v. 6, (3), 1995, NOV, p. 277-293
DELAGLIO, F.; GRZESIEK, S.; VUISTER, GW; ZHU, G.; PFEIFER, J.; BAX, A. Article

1994 4

Analysis of Sugar Puckers and Glycosidic Torsion Angles in a DNA G-Tetrad Structure by Heteronuclear Three-Bond J Couplings
J. Am. Chem Soc, v. 116, 1994, p. 8370-8371
Zhu, Guang; Live, David; Bax, Ad Article
Measurement of homo- and heteronuclear J couplings from quantitative J correlation
Methods in Enzymology, v. 239, 1994, p. 79-105
Bax, Ad; Vuister, Geerten W.; Grzesiek, Stephan; Delaglio, Frank; Wang, Andy C.; Tschudin, Rolf; Zhu, Guang Article
Measurement of two- and three-bond 1H-13C J couplings from quantitative heteronuclear J correlation for molecules with overlapping 1H resonances, Using T1 Noise Reduction
J. Magn. Reson Series A, v. 110, 1994, p. 257-261
Zhu, Guang; Renwick, Alistair; Bax, Ad Article
Stable Isotope Applications in Biomolecular Structure and Mechanisms
Stable Isotope Applications in Biomolecular Structure and Mechanisms, Edited by J. Trewhella, T.A. Cross and C. J. Unkefer, Los Alamos, New Mexico, 1994, 345 pages
Zhu, Guang; Live, David; Bax, Ad Article

1993 2

Discrete Fourier Transformation of NMR Signals. The Relationship between Sampling Delay Time and Spectral Baseline
J. Magn.Reson. Series A, v. 105, 1993, p. 219-222
Zhu, Guang; Torchia, Denis; Bax, Ad Article
Quantitative Measurement of Long-range 1H-13C J Couplings from Proton Detected HMBC Spectra.
J. Magn. Reson. Series A, v. 104, 1993, p. 353-357
Zhu, Guang; Bax, Ad Article

1992 2

Improved Linear Prediction of Truncated Damped Sinusoids Using modified Backward-Forward Linear Prediction
J.Magn.Reson, v. 100, 1992, p. 202-207
Zhu, Guang; Bax, Ad Article
Solution Structure of a Calmodulin-Target Peptide Complex by Multidimensional NMR
Science, v. 256, 1992, p. 632-638
Ikura, M.; Clore, G.M.; Gronenborn, A.M.; Zhu, Guang; Klee, C.B.; Bax, Ad Article

1991 3

Four-Dimensional Heteronuclear Triple Resonance NMR of Isotopically Enriched Proteins for Sequential assignment of Backbone atoms.
J. Magn. Reson, v. 91, 1991, p. 422-428
Kay, Lewis E.; Ikura, Mitsuhiko; Zhu, Guang; Bax, Ad Article
Removal of F1 Baseline Distortion and Optimization of Folding in Multi-Dimensional NMR Spectra
J. Magn. Reson, v. 91, 1991, p. 174-178
Bax, Ad; Ikura, Mitsuhiko; Kay, Lewis E.; Zhu, Guang Article
Two-dimensional Linear Prediction for Signals Truncated in Both Dimensions
J. Magn. Reson, v. 98, 1991, p. 192-199
Zhu, Guang; Bax, Ad Article

1990 1

Improved Linear Prediction for Truncated Signals of Known Phase.
J. Magn. Reson, v. 90, 1990, p. 405-410
Zhu, Guang; Bax, Ad Article

1988 1

Distribution of Energy in Polymers Due to Incident Electrons and Protons
Radiation Effec. and Defec. in Solids, v. 105, 1988, p. 303
Rustgi, M.L.; Pandey, L.N.; Wilson, J.W.; Long, S.A.T.; Zhu, Guang Article


No Publications






Teaching Assignment

---

2021-22 Winter 0 2021-22 Fall 1 2020-21 Summer 0 2020-21 Spring 6 2020-21 Winter 0 2020-21 Fall 3

---

LIFS6113E Current Topics in Biochemistry and Biophysics


BIBU4850 Biotechnology and Business Project Research
BIPH4010 Principles of Quantitative Instrumentation
LIFS4960 Biological Science Capstone Project
LIFS4961 Biochemistry and Cell Biology Capstone Project
LIFS4963 Biotechnology Capstone Project
SCIE1120 Chemistry and Life


BIBU4850 Biotechnology and Business Project Research
BIPH3010 Advanced Biological Physics
LIFS6113D Current Topics in Biochemistry and Biophysics


No Teaching Assignments


No Teaching Assignments


No Teaching Assignments






Research Postgraduate (RPG) Supervision From January 2019 to December 2022 (As of 30 January 2022)

---

All Supervisions Current RPGs Graduated RPGs

---

Current RPGs

---

Doctor of Philosophy YAN, Bing
Life Science( 2020 - )

FUNG, Chun Po
Life Science( 2018 - )

CHEN, Si
Life Science( 2017 - )

---

Master of Philosophy HUANG, Zeguo
Life Science( 2021 - )

SIU, Kwong Tai
Life Science( 2021 - )

SUEN, Ching Monica
Life Science( 2020 - )

---

Graduated RPGs

---

Doctor of Philosophy DIN, Rahman Ud
Life Science( Completed in 2021 )

SHI, Xiao
Life Science( Completed in 2021 )

MIAO, Haitao
Life Science( Completed in 2020 )

ULLAH, Ata
Life Science( Completed in 2020 )

YOU, Yingying
Life Science( Completed in 2019 )

---

Master of Philosophy CHOY, To To
Life Science( Completed in 2021 )









ProjectsFrom January 2020 to December 2022

---

All Projects 12 Leading Projects 7 Participating Projects 5

---

Center for Genomic Studies on Plant-Environment Interaction for Sustainable Agriculture and Food Security


植物与环境互作基因组研究中心：可持续农业与粮食安全 Participating


RGC - Areas of Excellence Scheme


Project Team (HKUST)
ZHU Guang


2021 -




Structural determination of G4C2 G-quadruplexes and their complexes with small molecule inhibitors


G4C2 G-四链体及其与小分子抑制剂的复合物的结构测定 Leading


RGC - General Research Fund


Project Team (HKUST)
ZHU Guang (Lead)


2021 -




Structural Determination of Human DNA Helicase Mcm2-7 by NMR and cryo-EM


DNA解旋酶Mcm2-7的NMR和cryo-EM结构解析 Leading


RGC - General Research Fund


Project Team (HKUST)
ZHU Guang (Lead)


2021 -




Phase Separation of Human Origin-Recognition Complex (ORC) Subunit 6-Mediated DNA Replication and its Role in Meier-Gorlin Syndrome


人源识别复合物（ORC）亚基6介导的DNA复制的相分离及其在Meier-Gorlin综合徵中的作用 Leading


RGC - General Research Fund


Project Team (HKUST)
ZHU Guang (Lead)


2020 -




Mechanistic study of G-quadruplex-mediated recognition of DNA replication origins in vertebrates


脊椎动物的四介导DNA 复制起源识别的机理研究 Leading


France / Hong Kong Joint Research Scheme


Project Team (HKUST)
ZHU Guang (Lead)


2020 - 2021




Preclinical study of the national category A new drug, the fourth-generation targeted therapy drug FMD001, for non-small cell lung cancer


国家一类新药第四代非小细胞肺癌靶向治疗药物FMD001的临床前研究 Participating


Shenzhen Science and Technology Innovation Committee


Project Team (HKUST)
ZHU Guang


2019 - 2021




Mechanistic study of ORC1 and TRF2 in EBNA1-mediated Epstein-Barr virus latent DNA replication


人类起始识别复合物1（ORC1）和端粒重复因子2（TRF2）在EB抗原1（EBNA1）介导的EB疱疹病毒潜伏期DNA复制中的机理研究 Leading


RGC - General Research Fund


Project Team (HKUST)
ZHU Guang (Lead)


2018 - 2021




Research on the Reconfigurable Visible Laser Light Communication SoC integrating Transceiver and Receiver Modules towards High Speed Data Communication among Buildings


面向楼宇间高速数据传输网络的可重构可见激光通信收发芯片的研究与设计 Participating


Shenzhen Science and Technology Innovation Committee


Project Team (HKUST)
YUE Chik Patrick (Lead)
ZHU Guang


2018 - 2020




Shenzhen Key Laboratory of Edible and Medicinal Resources


深圳市可食用及药用资源研究重点实验室 Participating


Shenzhen Science and Technology Innovation Committee


Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
LI Ning
ZHU Guang


2018 - 2020




Structure-function studies of pre replication complex in DNA replication of human and NPC cells


人类正常细胞和鼻咽癌细胞的DNA复制中前复制复合体的结构与功能研究 Leading


National Natural Science Foundation of China


Project Team (HKUST)
ZHU Guang (Lead)
LIU Changdong


2017 - 2020




Structure-function studies of DNA replication protein complexes Geminin/Cdt1 and Geminin/MCM


DNA复制蛋白复合物Geminin/Cdt1和Geminin/MCM的结构与功能研究 Leading


RGC - General Research Fund


Project Team (HKUST)
ZHU Guang (Lead)


2016 - 2020




State Key Laboratory of Molecular Neuroscience (The Hong Kong University of Science and Technology)


分子神经科学国家重点实验室（香港科技大学） Participating


Innovation and Technology Fund


Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHOW King Lau
CHUNG Kenny K
DAI Wei Min
GUO Zhihong
HUANG Pingbo
LIANG Chun
MILLER Andrew Leitch
POON Randy Yat Choi
QI Robert Zhong
TSIM Karl Wah Keung
WEN Zilong
WONG Joseph Tin Yum
WONG Yung Hou
WU Zhenguo
ZHU Guang


2011 -