Faculty Staff
Dr Choi, Siu Wai

BSc (Salford); PgDip (Sheffield); PhD (Ulster)





General Information
Title

Research Assistant Professor in Oral and Maxillofacial Surgery


Division

Oral and Maxillofacial Surgery


E-mail

htswchoi@hku.hk
>


Research profile

HKU Scholars Hub
>
Researcher ID
>
ORCID
>


Research Theme

Oral Cancer




Category
Publications Knowledge Exchange Grants


Advanced Sorting
Publications
Article
Agarwal S, Choi SW, Fletcher SN, Klein A, Gill R, Anderson L, Al‐Azzawi O, Arenas E, Bill KM, Burns H, Chawla A, Elder R, Fogg K, Gambino G, Garcia C, Giminez M, Hayes T, Hodek A, Mellor A, Mikhail C, Morrice D, O'Connor C, Place D, Riley E, Sandys S, Shaban I, Shaw M, Shepherd S, Singh H, Kadayam Sreenivasan R, Subramanian R, Walker C, Woodward D. The incidence and effect of resternotomy following cardiac surgery on morbidity and mortality: a 1‐year national audit on behalf of the Association of Cardiothoracic Anaesthesia and Critical Care, Anaesthesia 2021; 76(1): 19-26 doi:10.1111/anae.15070
Wang W, ADEOYE J, Thomson P, Choi SW. Statistical profiling of oral cancer and the prediction of outcome, Journal of Oral Pathology & Medicine 2021; 50(1): 39-46 doi:10.1111/jop.13110
Ramalingam G, Choi SW, Agarwal S, Kunst G, Gill R, Fletcher SN, Klein AA, The Association of Cardiothoracic Anaesthesia and Critical Care. Complications related to peri‐operative transoesophageal echocardiography – a one‐year prospective national audit by the Association of Cardiothoracic Anaesthesia and Critical Care, Anaesthesia 2020; 75(1): 21-26 doi:10.1111/anae.14734
Endlich Y, Beckmann LA, Choi SW, Culwick MD. A prospective six-month audit of airway incidents during anaesthesia in twelve tertiary level hospitals across Australia and New Zealand, Anaesthesia and Intensive Care 2020; 48(5): 389-398 doi:10.1177/**X**
Chu CS, Lee NP, ADEOYE J, Thomson P, Choi SW. Machine Learning and Treatment Outcome Prediction for Oral Cancer, Journal of Oral Pathology & Medicine 2020; Epub 2020-08-02 doi:10.1111/jop.13089
ADEOYE J, Thomson P, Choi SW. Prognostic significance of multi‐positive invasive histopathology in oral cancer, Journal of Oral Pathology & Medicine 2020; Epub 2020-08-02 doi:10.1111/jop.13086
ADEOYE J, Chu CS, Choi SW, Thomson P. Oral Cancer Awareness and Individuals’ Inclination to Its Screening and Risk Prediction in Hong Kong, Journal of Cancer Education 2020; Epub 2020-07-23 doi:10.1007/s13187-020-01834-x
Adeoye J, Choi SW, Thomson P. Bayesian Disease Mapping and the ‘High‐Risk’ Oral Cancer Population in Hong Kong, Journal of Oral Pathology & Medicine 2020; 49(9): 907-913 doi:10.1111/jop.13045
Choi S-W, Thomson P. Multiple oral cancer development—Clinico‐pathological features in the Hong Kong population, Journal of Oral Pathology & Medicine 2020; 49(2): 145-149 doi:10.1111/jop.12962
Leifer S., Choi S. W., Asanati K., Yentis S. M.. Upper limb disorders in anaesthetists – a survey of Association of Anaesthetists members, Anaesthesia 2019; 74(3): 285-291 doi:10.1111/anae.14446
Choi SW, Leung FKL, Lau TW, Wong GTC. Impact of postoperative haemoglobin on length of stay post fractured hip repair in patients with standardised perioperative management, Hip International 2019; 29(2): 172-176 doi:10.1177/73428
Choi SW, Thomson P. Increasing Incidence of Oral Cancer in Hong Kong – Who, Where…and Why?, Journal of Oral Pathology & Medicine 2019; 48(6): 483-490 doi:10.1111/jop.12868
Cheung V., Yuen V. M., Wong G. T.C., Choi S. W.. The effect of sleep deprivation and disruption on DNA damage and health of doctors, Anaesthesia 2019; 74(4): 434-440 doi:10.1111/anae.14533
Charlesworth M., Choi S. W.. Non-inferiority studies: is ‘better’ the enemy of ‘good enough’?, Anaesthesia 2018; 73(9): 1162-1164 doi:10.1111/anae.14401
Irwin M. G., Choi S. W.. If there is a 50-50 chance that something is correct, then nine times out of ten it will be… Bayesian network meta-analyses in Anaesthesia, Anaesthesia 2018; 73(8): 927-931 doi:10.1111/anae.14301
Choi SW, Wong GTC. Doctor, why are you driving a wedge between us? Calculating sample size in multiple testing and the need for Geisser-Greenhouse correction, Anaesthesia 2018; 73(12): 1564-1566 doi:10.1111/anae.14477
Wong SCS, Choi SW, Cheung CW. A comparison of chronic pain with and without neuropathic characteristics in a Hong Kong Chinese population: an analysis of pain related outcomes and patient help seeking behaviour, PLoS ONE 2018; 13(10): article no. e**-article no. e** doi:10.1371/journal.pone.**
Choi SW, Wong GTC. Quality improvement studies - pitfalls of the before and after study design, Anaesthesia 2018; 73(11): 1432-1435 doi:10.1111/anae.14451
Choi SW, Ho CK. Antioxidant properties of drugs used in Type 2 diabetes management: could they contribute to, confound or conceal effects of antioxidant therapy?, Redox Report 2018; 23(1): 1-24 doi:10.1080/**.2017.**
Choi SW. Safety of hydroxyethyl starch 130/0.4 in paediatric cardiac patients - statistical note, Anaesthesia 2018; 73(5): 652-652 doi:10.1111/anae.14293
Wong SSC, Choi SW, Lee Y, Irwin MG, Cheung CW. The analgesic effects of intraoperative total intravenous anesthesia (TIVA) with propofol versus sevoflurane after colorectal surgery, Medicine 2018; 97(31): article no. e11615-article no. e11615 doi:10.1097/MD.1615
Choi SW, Wong GTC. The art and science of statistical predictions: does a picture need a thousand words?, Anaesthesia 2018; 73(6): 784-787 doi:10.1111/anae.14282
Choi SW, Wong GTC. Assumptions and associations under pressure, Anaesthesia 2018; 73(7): 901-903 doi:10.1111/anae.14325
Thomson P, Su R, Choi SW. Oral cancer in Hong Kong: identifying and managing the ‘high-risk’ population, Faculty Dental Journal 2018; 9(3): 116-121 doi:10.1308/rcsfdj.2018.116
Wong GTC, Choi SW, Tran DH, Kulkarni H, Irwin M. An international survey evaluating factors influencing the use of total intravenous anaesthesia, Anaesthesia and Intensive Care 2018; 46(3): 332-338 doi:10.1177/**X
Choi SW, Wong GTC. Before and after studies and historical controls. Is the proof in the pudding?, Anaesthesia 2018; 73(5): 642-644 doi:10.1111/anae.14249
Choi SW, Charlesworth M, Wong GTC. A good pilot to navigate troubled waters, Anaesthesia 2018; 73(4): 512-514 doi:10.1111/anae.14223
Mu JJ, Jiang T, Deng LP, Choi SW, Irwin MG, Yuen VMY. A comparison of two techniques for induction of anaesthesia with target-controlled infusion of propofol, Anaesthesia 2018; 73(12): 1507-1514 doi:10.1111/anae.14355
Choi SW, Wong GTC. Big data, big problems: causation, confounders and cohorts, Anaesthesia 2018; 73(3): 384-387 doi:10.1111/anae.14214
Choi SW, Lam DMH. Missing in action - where have all the data gone!?, Anaesthesia 2017; 72(9): 1146-1148 doi:10.1111/anae.14001
Ho Cyrus K., Choi Siu Wai, Fung Matthew S., Benzie Iris F.F.. Tea polyphenols: Absorption, bioavailability and potential toxicity, CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources 2017; 12: article no. 002-article no. 002 doi:10.1079/PAVSNNR
Wong GTC, Ang WC, Wong TCL, Choi SW. Surgical Outcome Risk Tool (SORT) validation in hepatectomy, Anaesthesia 2017; 72(10): 1287-1289 doi:10.1111/anae.14051
Choi SW, Lam DM, Wong SCS, Shiu HC, Wang XMA, Cheung CW. Effects of Single Nucleotide Polymorphisms on Surgical and Postsurgical Opioid Requirements: A Systematic Review and Meta-analysis, The Clinical Journal of Pain 2017; 33(12): 1117-1130 doi:10.1097/AJP.0498
Scott HB, Choi SW, Wong GTC, Irwin MG. The effect of remifentanil on propofol requirements to achieve loss of response to command vs. loss of response to pain, Anaesthesia 2017; 72(4): 479-487 doi:10.1111/anae.13781
Yuen VM, Li BL, Cheuk DK, Leung MKM, Hui TWC, Wong IC, Lam WW, Choi SW, Irwin MG. A randomised controlled trial of oral chloral hydrate vs. intranasal dexmedetomidine before computerised tomography in children, Anaesthesia 2017; 72(10): 1191-1195 doi:10.1111/anae.13981
Yuen V., Chen C., Liu L., Wang C. Y., Choi S. W.. Ultrasound examination of gastric contents: are qualitative and quantitative assessments complementary? A reply, Anaesthesia 2017; 72(10): 1281-1282 doi:10.1111/anae.14055
Choi S. W., Lam D. M.H.. Classifying variables, Anaesthesia 2017; 72(1): 122-123 doi:10.1111/anae.13753
Choi S. W., Lam D. M.H.. Credible control groups and blinding, Anaesthesia 2017; 72(3): 402-404 doi:10.1111/anae.13811
Choi S. W., Lam D. M.H.. Comparing two methods–agreeing to disagree?, Anaesthesia 2017; 72(5): 651-653 doi:10.1111/anae.13874
Chen C., Liu L., Wang C. Y., Choi S. W., Yuen V. M.. A pilot study of ultrasound evaluation of gastric emptying in patients with end-stage renal failure: a comparison with healthy controls, Anaesthesia 2017; 72(6): 714-718 doi:10.1111/anae.13869
Choi SW, Lam DMH. Size matters, Anaesthesia 2017; 72(10): 1273-1276 doi:10.1111/anae.14030
Choi SW, Lam DMH. Comparing times in clinical studies with a finite ending, Anaesthesia 2017; 72(12): 1554-1556 doi:10.1111/anae.14122
Choi SW, Lam DMH. How to describe your data - the devil is in the distribution, Anaesthesia 2017; 72(11): 1412-1414 doi:10.1111/anae.14081
Monteiro RS, Pillai A, Choi SW, Bogod D, Yentis SM. Flow characteristics of Luer and non-Luer spinal needles, Anaesthesia 2017; 72(6): 749-754 doi:10.1111/anae.13851
Smith AF, Choi SW. Major trauma and the need for massive transfusion, Anaesthesia 2017; 72(11): 1299-1301 doi:10.1111/anae.14031
Choi SW, Lam DMH. Regression: How much data do I really need?, Anaesthesia 2017; 72(8): 1029-1030 doi:10.1111/anae.13937
Pillai A, Monteiro RS, Choi SW, Yentis SM, Bogod D. Strength of commonly used spinal needles: the ability to deform and resist deformation, Anaesthesia 2017; 72(9): 1125-1133 doi:10.1111/anae.13959
Choi SW, Lam DMH. Inter-rater agreement - Agreeing to disagree, again!, Anaesthesia 2017; 72(6): 778-780 doi:10.1111/anae.13898
Brindani N, Mena P, Calani L, Benzie I, Choi SW, Brighenti F, Zanardi F, Curti C, Del Rio D. Synthetic and analytical strategies for the quantification of phenyl-γ-valerolactone conjugated metabolites in human urine, Molecular Nutrition & Food Research 2017; 61(9): article no. **-article no. ** doi:10.1002/mnfr.
Choi SW, Lam DMH. Heterogeneity in meta-analyses. Comparing apples and oranges?, Anaesthesia 2017; 72(4): 532-534 doi:10.1111/anae.13832
Choi S. W., Tran D. H.D.. Calculating sample size. Alpha, Beta, Mu and Sigma - It's all Greek, Anaesthesia 2016; 71(4): 462-464 doi:10.1111/anae.13369
Choi SW, Cheung CW. The case of the misleading composite - one outcome is better than two, Anaesthesia 2016; 71(9): 1101-1103 doi:10.1111/anae.13590
Choi S. W., Lam David M.H.. Please please me, Hong Kong Medical Journal 2016; 22(1): 85-86 doi:10.12809/hkmj154738
Choi S. W., Lam D. M.H.. Funnels for publication bias - Have we lost the plot?, Anaesthesia 2016; 71(3): 338-341 doi:10.1111/anae.13355
Choi S. W., Tran D. H.D.. Heart attacks prevent chocolate. Or, the differences between correlation and causation, Anaesthesia 2016; 71(5): 586-589 doi:10.1111/anae.13402
Choi S. W.. Odds, risks, and other numbers needed to complicate things, Anaesthesia 2016; 71(10): 1234-1236 doi:10.1111/anae.13630
Choi S. W., Lam D. M.H.. A little less conversation, Anaesthesia 2016; 71(12): 1482-1487 doi:10.1111/anae.13703
Choi S. W.. Life is lognormal! What to do when your data does not follow a normal distribution, Anaesthesia 2016; 71(11): 1363-1366 doi:10.1111/anae.13666
Choi S. W., Lam D. M.H.. Trials and tribulations of a meta-analyst, Anaesthesia 2016; 71(2): 228-231 doi:10.1111/anae.13334
Choi S. W., Lam D. M.H.. An alarm for a false alarm, Anaesthesia 2016; 71(1): 106-108 doi:10.1111/anae.13300
Cheung CW, Choi SW, Wong SCS, Lee Y, Irwin MG. Changes in Prevalence, Outcomes, and Help-seeking Behavior of Chronic Pain in an Aging Population Over the Last Decade, Pain Practice 2016; 17(5): 643-654 doi:10.1111/papr.12496
Choi SW, Cheung CW. Don't judge a book by its cover, don't judge a study by its abstract. Common statistical errors seen in medical papers, Anaesthesia 2016; 71(7): 843-845 doi:10.1111/anae.13506
Qiu Q, Choi SW, Wong SSC, Irwin MG, Cheung CW. Effects of intra-operative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Anaesthesia 2016; 71(10): 1222-1233 doi:10.1111/anae.13578
Choi SW, Lam DM, Irwin MG. Ghost in the machine, Hong Kong Medical Journal 2016; 22(3): 292-293 doi:10.12809/hkmj154695
Choi SW, Wong GTC. It's just a standard deviation!, Anaesthesia 2016; 71(8): 969-971 doi:10.1111/anae.13565
Chan ACS, Qiu Q, Choi SW, Wong SSC, Chan ACY, Irwin MG, Cheung CW. Effects of Intra-Operative Total Intravenous Anaesthesia with Propofol versus Inhalational Anaesthesia with Sevoflurane on Post-Operative Pain in Liver Surgery: A Retrospective Case-Control Study, PLoS ONE 2016; 11(2): article no. e**-article no. e** doi:10.1371/journal.pone.**
Choi SW, Wong GTC. If at first you don't succeed, try and try again? The dangers of multiple comparisons, Anaesthesia 2016; 71(6): 718-720 doi:10.1111/anae.13468
Lam DMH, Choi SW, Wong SSC, Irwin MG, Cheung CW. Efficacy of Pregabalin in Acute Postoperative Pain Under Different Surgical Categories: A Meta-Analysis, Medicine 2015; 94(46): article no. e1944-article no. e1944 doi:10.1097/MD.1944
Liman S, Cheung CW, Wong KL, Tai W, Qiu Q, Ng KF, Choi SW, Irwin M. Preventive Treatment with Ketamine attenuates the ischaemia-reperfusion response in a chronic postischaemia pain model, Oxidative Medicine and Cellular Longevity 2015; 2015: article no. 380403-article no. 380403 doi:10.1155/2015/380403
Au AH, Choi SW, Cheung CW, Leung MYY. The Efficacy and Clinical Safety of Various Analgesic Combinations for Post-Operative Pain after Third Molar Surgery: A Systematic Review and Meta-Analysis, PLoS ONE 2015; 10(6): article no. e**-article no. e** doi:10.1371/journal.pone.**
Choi Siu Wai, Yeung Vincent T.F., Collins Andrew R., Benzie Iris F.F.. Redox-linked effects of green tea on DNA damage and repair, and influence of microsatellite polymorphism in HMOX-1: Results of a human intervention trial, Mutagenesis 2015; 30(1): 129-137 doi:10.1093/mutage/geu022
Choi S. W., Lam David M H, Irwin Michael G.. The dark side of the moon, Hong Kong Medical Journal 2015; 21(5): 476-477 doi:10.12809/hkmj154631
Ho Cyrus K., Choi Siu Wai, Siu Parco M., Benzie Iris F F. Effects of single dose and regular intake of green tea (Camellia sinensis) on DNA damage, DNA repair, and heme oxygenase-1 expression in a randomized controlled human supplementation study, Molecular Nutrition and Food Research 2014; 58(6): 1379-1383 doi:10.1002/mnfr.
Cheung CW, Qiu Q, Choi SW, Moore BJ, Goucke R, Irwin M. Chronic opioid therapy for chronic non-cancer pain: a review and comparison of treatment guidelines, Pain Physician 2014; 17(5): 401-414
Cheung CW, Qiu Q, Ying ACL, Choi SW, Law WL, Irwin MG. The effects of intra-operative dexmedetomidine on postoperative pain, side-effects and recovery in colorectal surgery, Anaesthesia 2014; 69(11): 1214-1221 doi:10.1111/anae.12759
Ho Cyrus K., Choi Siu-Wai, Siu Parco M., Benzie Iris F.. Genoprotection and genotoxicity of green tea (Camellia sinensis): Are they two sides of the same redox coin?, Redox Report 2013; 18(4): 150-154 doi:10.1179/Y.
Fung Shing Tack, Ho Cyrus K., Choi Siu Wai, Chung Wai Yuen, Benzie Iris F.F.. Comparison of catechin profiles in human plasma and urine after single dosing and regular intake of green tea (Camellia sinensis), British Journal of Nutrition 2013; 109(12): 2199-2207 doi:10.1017/S00071**
Choi Siu Wai, Fai Yeung Vincent Tok, Benzie Iris F.F.. Heme oxygenase microsatellite polymorphism, oxidative stress, glycemic control, and complication development in type 2 diabetes patients, Free Radical Biology and Medicine 2012; 53(1): 60-63 doi:10.1016/j.freeradbiomed.2012.04.017
Ho Cyrus K., Choi Siu Wai, Siu Parco M., Benzie Iris F.F.. Cryopreservation and storage effects on cell numbers and DNA damage in human lymphocytes, Biopreservation and Biobanking 2011; 9(4): 343-347 doi:10.1089/bio.2011.0024
Lam Carly S.Y., Benzie Iris F.F., Choi Siu Wai, Chan Lily Y.L., Yeung Vincent T.F., Woo George C.. Relationships among diabetic retinopathy, antioxidants, and glycemic control, Optometry and Vision Science 2011; 88(2): 251-256 doi:10.1097/OPX.0b013ea
Wachtel-Galor Sissi, Wong Wan Chi, Choi Siu Wai, Benzie Iris F.F.. Antioxidant power and DNA repair effects of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (W.Curt.:Fr.) P. Karst. (Aphyllophoromycetideae), in human acute post-ingestion study, International Journal of Medicinal Mushrooms 2010; 12(4): 359-366 doi:10.1615/IntJMedMushr.v12.i4.30
Choi Siu Wai, Benzie Iris F.F., Ma Shuk Woon, Strain J. J., Hannigan Bernadette M.. Acute hyperglycemia and oxidative stress: Direct cause and effect?, Free Radical Biology and Medicine 2008; 44(7): 1217-1231 doi:10.1016/j.freeradbiomed.2007.12.005
Wachtel-Galor Sissi, Choi Siu Wai, Benzie Iris F.F.. Effect of Ganoderma lucidum on human DNA is dose dependent and mediated by hydrogen peroxide, Redox Report 2005; 10(3): 145-149 doi:10.1179/X57355
Szeto Y. T., Benzie I. F.F., Collins A. R., Choi S. W., Cheng C. Y., Yow C. M.N., Tse M. M.Y.. A buccal cell model comet assay: Development and evaluation for human biomonitoring and nutritional studies, Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 2005; 578(1-2): 371-381 doi:10.1016/j.mrfmmm.2005.06.014
Choi S. W., Benzie Iris, Lam C. S.Y., Chat S. W.S., Lam J., Yiu C. H., Kwan J. J., Tang Y. H., Yeung G. S.P., Yeung V. T.F., Woo G. C., Hannigan B. M., Strain J. J.. Inter-relationships between DNA damage, ascorbic acid and glycaemic control in Type 2 diabetes mellitus, Diabetic Medicine 2005; 22(10): 1347-1353 doi:10.1111/j.1464-5491.2005.01647.x
Choi S. W., Benzie I. F.F., Collins A. R., Hannigan B. M., Strain J. J.. Vitamins C and E: Acute interactive effects on biomarkers of antioxidant defence and oxidative stress, Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 2004; 551(1-2): 109-117 doi:10.1016/j.mrfmmm.2004.03.006
Conference Paper
Choi SW, Thomson PJ. Profiling the oral cancer population in Hong Kong, IADR/AADR/CADR 2019 General Session & Exhibition 2019;
Wong SCS, Choi SW, Cheung CW. Intraoperative Total Intravenous Anaesthesia is associated with reduced postoperative opioid consumption after colorectal surgery, 17th World Congress on Pain (2018) 2018;
Book Chapter
Choi SW, Ho CKC. Antioxidant properties of drugs used in type 2 diabetes management . Diabetes: Oxidative Stress and Dietary Antioxidants (2nd ed.). London: Academic Press / Elsevier; 2020:139-148.
Benzie Iris F.F., Choi Siu Wai. Antioxidants in food: Content, measurement, significance, action, cautions, caveats, and research needs . Advances in Food and Nutrition Research. 2014:: 1-53.

Knowledge Exchange
19 March 2019: Thomson Peter James, Choi Siu Wai. Press Conference on Oral Cancer Prevalence .
16 February 2019: Thomson Peter James, Choi Siu Wai, Curtin Justin Paul, Irwin Michael Garnet, Wong Gordon Tin Chun. Cancer & Chronic Disease Care: Adjunctive Tools for Diagnosis and Prevention.

Grants
Project Title: Investigation and enumeration of circulating tumour cells during different stages of oral cavity cancer
Grant Type: Health and Medical Research Fund - Full Grant
Funding Year: 2019
Amount: HKD**
Principal Investigator: Dr Choi, Siu Wai
Co-investigator(s): Dr Curtin Justin Paul, Professor Lam Alfred King-yin, Professor Thomson Peter James