Faculty Staff
Professor Zhang, Chengfei

DDS, PhD (Peking U)





General Information
Title

Clinical Professor in Endodontics


Division

Restorative Dental Sciences


E-mail

zhangcf@hku.hk
>


Phone Number

2859 0525


Research profile

HKU Scholars Hub
>
Scopus
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ORCID
>
ResearchGate
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Research Theme

Craniofacial Regeneration



Areas of Research Expertise

Regenerative endodontics
Microbiological aspects of endodontics
Application of lasers in dentistry




Category
Publications Honours and Awards Editorships Knowledge Exchange Professional Societies Grants Invited Lectures and Keynote Speeches HKU Committee Appointments


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Publications
Article
CHOPRA H, HAN Y, Zhang C, Pow EHN. CD133+CD34+ cells can give rise to EPCs: A comparative rabbit and human study, Blood Cells, Molecules and Diseases 2021; 86: article no. 102487-article no. 102487 doi:10.1016/j.bcmd.2020.102487
Gailicia JC, Mungia R, Taverna MV, Mendoza MJ, Estrela C, Gaudin A, Zhang C, Vaughn BA, Khan AA. Response by Endodontists to the SARS-CoV-2 (COVID?19) Pandemic: An International Survey, Frontiers in Dental Medicine 2021; 1: article no. 617440-article no. 617440 doi:10.3389/fdmed.2020.617440
Baig MMFA, Zou T, Neelakantan P, Zhang C. Development and functionalization of DNA nanostructures for biomedical applications, Journal of the Chinese Chemical Society 2021; 68(2): 228-238 doi:10.1002/jccs.
Baig MMFA, Zhang C, Akhtar MF, Saleem A, Naveed N. Treatment of Wilms’ nephroblastoma cancer cells via EGFR targeting of dactinomycin loaded DNA-nanowires, Journal of Pharmaceutical Investigation 2021; 51: 233-242 doi:10.1007/s40005-020-00509-5
Liu J, Zou T, Yao Q, ZHANG Y, Zhao Y, Zhang C. Hypoxia-mimicking cobalt-doped multi-walled carbon nanotube nanocomposites enhance the angiogenic capacity of stem cells from apical papilla, Materials Science and Engineering: C 2021; 120: article no. 111797-article no. 111797 doi:10.1016/j.msec.2020.111797
Tian X, Lu Z, Ma C, Wu M, Zhang C, Yuan Y, Yuan X, Xie D, Liu C, Guo J. Antimicrobial hydroxyapatite and its composites for the repair of infected femoral condyle, Materials Science and Engineering: C 2021; 121: article no. 111807-article no. 111807 doi:10.1016/j.msec.2020.111807
Yeung AWK, Harper B, Zhang C, Neelakantan P, Bornstein MM. Do different cone beam computed tomography exposure protocols influence subjective image quality prior to and after root canal treatment?, Clinical Oral Investigations 2021; 25: 2119-2127 doi:10.1007/s00784-020-03524-w
Wong J, Zou T, Lee AHC, Zhang C. The Potential Translational Applications of Nanoparticles in Endodontics, International Journal of Nanomedicine 2021; 16: 2087-2106 doi:10.2147/IJN.S293518
Zhu Z, Ying Z, Zeng M, Zhang Q, Liao G, Liang Y, Li C, Zhang C, Wang X, Jiang W, Luan P, Sha O. Trichosanthin cooperates with Granzyme B to restrain tumor formation in tongue squamous cell carcinoma, BMC Complementary Medicine and Therapies 2021; 21: article no. 88-article no. 88 doi:10.1186/s12906-021-03266-6
Wu L, Jiang S, Ge H, Cai Z, Huang X, Zhang C. Effect of Optimized Irrigation With Photon‐Induced Photoacoustic Streaming on Smear Layer Removal, Dentin Microhardness, Attachment Morphology, and Survival of the Stem Cells of Apical Papilla, Lasers in Surgery and Medicine 2021; Epub 2021-03-25 doi:10.1002/lsm.23394
Wong J, Lee A, Zhang C. Diagnosis and Management of Apical Fenestrations Associated with Endodontic Diseases: A Literature Review, European Endodontic Journal 2021; 6(1): 25-33 doi:10.14744/eej.2020.51422
Li X, Wei L, Li J, Shao J, YI B, Zhang C, Liu H, Ma B, Ge S. Multifunctional SDF-1-loaded hydroxyapatite/polylactic acid membranes promote cell recruitment, immunomodulation, angiogenesis, and osteogenesis for biomimetic bone regeneration, Applied Materials Today 2021; 22: article no. 100942-article no. 100942 doi:10.1016/j.apmt.2021.100942
Zhang J, Zhao IS, Yu OY, Li QL, Mei ML, Zhang C, Chu CH. Layer-by-layer self‐assembly polyelectrolytes loaded with cyclic adenosine monophosphate enhances the osteo/odontogenic differentiation of stem cells from apical papilla, Journal of Biomedical Materials Research Part A 2021; 109(2): 207-218 doi:10.1002/jbm.a.37017
Qi Y, Zou T, Dissanayaka WL, Wong HM, Bertassoni LE, Zhang C. Fabrication of tapered fluidic microchannels conductive to angiogenetic sprouting within gelatin methacryloyl hydrogels, Journal of Endodontics 2021; 47, 52-61
Chen Q, Yuan C, Jiang S, Heng BC, Zou T, Shen Z, Wang P, Zhang C. Small molecules efficiently reprogram apical papilla stem cells into neuron?like cells, Experimental and Therapeutic Medicine 2021; 21(6): article no. 546-article no. 546 doi:10.3892/etm.2021.9978
ZHANG Y, LIU J, Zou T, Qi Y, YI B, Dissanayaka WL, Zhang C. DPSCs treated by TGF-β1 regulate angiogenic sprouting of three-dimensionally co-cultured HUVECs and DPSCs through VEGF-Ang-Tie2 signaling, Stem Cell Research & Therapy 2021; 12(1): article no. 281-article no. 281 doi:10.1186/s13287-021-02349-y
YI B, Ding T, Jiang S, Gong T, Chopra H, Sha O, Dissanayaka WL, Ge S, Zhang C. Conversion of stem cells from apical papilla into endothelial cells by small molecules and growth factors, Stem Cell Research & Therapy 2021; 12: article no. 266-article no. 266 doi:10.1186/s13287-021-02350-5
POON CH, Wang Y, Fung ML, Zhang C, Lim LW. Rodent models of amyloid-beta feature in Alzheimer’s disease: Development and potential treatment implications, Aging and Disease 2020; 11
Wong KY, ROY J, Fung ML, Heng BC, Zhang C, Lim LW. Relationships between mitochondrial dysfunction and neurotransmission failure in Alzheimer’s disease, Aging and Disease 2020; Epub 2020-10-01, v. 11 n. 5 doi:10.14336/AD.2019.1125
Wang W, Yuan C, Geng T, Liu Y, ZHU S, Zhang C, Liu Z, Wang P. Lipopolysaccharide inhibits osteogenic differentiation of periodontal ligament stem cells partially through toll-like receptor 4-mediated ephrinB2 downregulation, Clinical Oral Investigations 2020; Epub 2020-01-23 doi:10.1007/s00784-020-03211-w
Zhu S, Liu Z, Yuan C, Lin Y, Yang Y, Wang H, Zhang C, Wang P, Gu M. Bidirectional ephrinB2?EphB4 signaling regulates the osteogenic differentiation of canine periodontal ligament stem cells, International Journal of Molecular Medicine 2020; 45(3): 897-909 doi:10.3892/ijmm.2020.4473
HAN Y, GONG T, Zhang C, Dissanayaka WL. HIF-1α Stabilization Enhances Angio-/Vasculogenic Properties of SHED, Journal of Dental Research 2020; Epub 2020-04-16: ** doi:10.1177/2190
Ren C, McGrath C, Gu M, Jin L, Zhang C, Sum FHKMH, Wong KWF, Chau ACM, Yang Y. Low-level laser-aided orthodontic treatment of periodontally compromised patients: a randomised controlled trial, Lasers in Medical Science 2020; 35(3): 729-739 doi:10.1007/s10103-019-02923-0
Dissanayaka WL, HAN Y, ZHANG L, Zou T, Zhang C. Bcl-2 Overexpression and Hypoxia Synergistically Enhance Angiogenic Properties of Dental Pulp Stem Cells, International Journal of Molecular Sciences 2020; 21(17): article no. 6159-article no. 6159 doi:10.3390/ijms**
LIAO C, Zhang C, Jin L, Yang Y. IL‐17 alters the mesenchymal stem cell niche towards osteogenesis in cooperation with osteocytes, Journal of Cellular Physiology 2020; 235(5): 4466-4480 doi:10.1002/jcp.29323
Wong J, Lee AHC, Zhang C. Effect of COVID-19 on Dental Education and Endodontic Practice in Hong Kong, Frontiers in Dental Medicine 2020; 1: article no. 569225-article no. 569225 doi:10.3389/fdmed.2020.569225
LIU J, Wang X, Song M, Du J, Yu J, Zheng W, Zhang C, Wang Y. MiR-497-5p Regulates Osteo/Odontogenic Differentiation of Stem Cells From Apical Papilla via the Smad Signaling Pathway by Targeting Smurf2, Frontiers in Genetics 2020; 11: article no. 582366-article no. 582366 doi:10.3389/fgene.2020.582366
Baig MMFA, Zhang C, Akhtar MF, Saleem A, Mudassir J. The effective transfection of a low dose of negatively charged drug-loaded DNA-nanocarriers into cancer cells via scavenger receptors, Journal of Pharmaceutical Analysis 2020; doi:10.1016/j.jpha.2020.10.003
Jiang S, Zhang C, Zou T. Single-Atom Catalysts for Biotherapy Applications: A Systematic Review, Nanomaterials 2020; 10: article no. 2518-article no. 2518 doi:10.3390/nano**
ZHU L, Dissanayaka WL, Zhang C. Dental pulp stem cells overexpressing stromal-derived factor-1α and vascular endothelial growth factor in dental pulp regeneration, Clinical Oral Investigations 2019; 23: 2497-2509 doi:10.1007/s00784-018-2699-0
Wang S, Heng BCA, Qiu S, Deng J, Cheung GSP, Jin L, Zhao B, Zhang C. Lipoteichoic acid of Enterococcus faecalis inhibits osteoclastogenesis via transcription factor RBP-J, Innate Immunity 2019; 25: 13-21 doi:10.1177/**12646
Zhang J, Zhang C, Quan LL, Chu CH. Cyclic Adenosine Monophosphate Promotes Odonto/Osteogenic Differentiation of Stem Cells from the Apical Papilla via Suppression of Transforming Growth Factor Beta 1 Signaling, Journal of Endodontics 2019; 45(2): 150-155 doi:10.1016/j.joen.2018.10.008
Yang C, Liu X, Zhao K, Zhu Y, Hu B, Zhou Y, Wang M, Wu Y, Zhang C, Xu J, Ning Y, Zou D. miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration in critical size defects, Stem Cell Research & Therapy 2019; 10(65): 1-11 doi:10.1186/s13287-019-1168-2
Yuan C, Wang P, Zhu S, Liu Z, Wen W, Geng T, Dissanayaka WL, Jin L, Zhang C. Overexpression of ephrinB2 in stem cells from apical papilla accelerates angiogenesis, Oral Diseases 2019; 25(3): 848-859 doi:10.1111/odi.13042
Heng BCA, Jiang S, YI B, GONG T, Lim LW, Zhang C. Small molecules enhance neurogenic differentiation of dental-derived adult stem cells, Archives of Oral Biology 2019; 102: 26-38 doi:10.1016/j.archoralbio.2019.03.024
Huang S, Zheng B, Jin X, Yu Q, Zhang X, Sun X, Chen Y, Ren X, Wismeijer D, Ma J, Zhang C, Wu G, Pan Y. Blockade of Cyclophilin D Attenuates Oxidative Stress-Induced Cell Death in Human Dental Pulp Cells, Oxidative Medicine and Cellular Longevity 2019; 2019: **:1-**:15 doi:10.1155/2019/**
GONG T, Xu J, Heng B, Qiu S, YI B, Han Y, Lo ECM, Zhang C. EphrinB2/EphB4 Signaling Regulates DPSCs to Induce Sprouting Angiogenesis of Endothelial Cells, Journal of Dental Research 2019; 98(7): 803-812 doi:10.1177/3886
Zou T, Jiang S, Dissanayaka WL, Heng BC, Xu J, Gong T, Huang X, Zhang C. Sema4d/plexinb1 Promotes Endothelial Differentiation Of Dental Pulp Stem Cells Via Activation Of Akt And Erk1/2 Signaling., Journal of Cellular Biochemistry 2019; 120(8): 13614-13624 doi:10.1002/jcb.28635
Jing Y, GONG T, Duan CG, Wang H, Zhang CF, Neelakantan P. In vitro cytocompatibility and osteogenic potential of calcium silicate-based dental cements in a root canal-filling model, Journal of International Medical Research 2019; Epub 2019-12-01: ** doi:10.1177/4801
Li M, Zhang C, Yang Y. Effects of mechanical forces on osteogenesis and osteoclastogenesis in human periodontal ligament fibroblasts: A systematic review of in vitro studies, Bone & Joint Research 2019; 8(1): 19-31 doi:10.1302/2046-3758.81.BJR-2018-0060.R1
Neelakantan P, Feroz Khan KK, Ng PH, Chui YY, Zhang C, Cheung GSP. Does the Orifice-directed Dentin Conservation Access Design Debride Pulp Chamber and Mesial Root Canal Systems of Mandibular Molars Similar to a Traditional Access Design?, Journal of Endodontics 2018; 44: 274-279 doi:10.1016/j.joen.2017.10.010
Li X, Li X, Wang S, Leung CFK, Zhang C, Jin L. Infiltration and Profiles of Mesoporous Silica Nanoparticles in Dentinal Tubules, ACS Biomaterials Science & Engineering 2018; 4: 1428-1436 doi:10.1021/acsbiomaterials.7b00919
Xu J, Gong T, Wang YY, Zou T, Heng BCA, Yang Y, Zhang C. Inhibition of TGF-β Signaling in SHED Enhances Endothelial Differentiation, Journal of Dental Research 2018; 97(2): 218-225 doi:10.1177/3741
Heng BCA, GONG T, XU J, Lim LW, Zhang C. EphrinB2 signalling modulates the neural differentiation of human dental pulp stem cells, Biomedical Reports 2018; 9(2): 161-168 doi:10.3892/br.2018.1108
Chopra H, Liao C, Zhang C, Pow EHN. Lapine periodontal ligament stem cells for musculoskeletal research in preclinical animal trials, Journal of Translational Medicine 2018; 16(1): article no. 174-article no. 174 doi:10.1186/s12967-018-1551-2
Tsui KH, Li X, Tsoi KH, Leung SF, Lei T, Chan WY, Zhang C, Chen J, Cheung GSP, Fan Z. Low-cost, flexible, disinfectant-free and regular-array three-dimensional nanopyramid antibacterial films for clinical applications, Nanoscale 2018; 10: 10436-10442 doi:10.1039/C8NR01968A
Ni N, Cao S, Han L, Zhang L, Ye J, Zhang C. Cone-beam computed tomography analysis of root canal morphology in mandibular first molars in a Chinese population: a clinical study, Evidence-Based Endodontics 2018; 3(1): article no. 1, p. 1-article no. 1, p. 6 doi:10.1186/s41121-018-0015-8
CHOPRA H, Hung MK, Kwong DL, Zhang CF, Pow EHN. Insights into Endothelial Progenitor Cells: Origin, Classification, Potentials, and Prospects, Stem Cells International 2018; 2018: article no. **-article no. ** doi:10.1155/2018/**
Shetty H, Shetty S, Kakade A, Desai R, Zhang CF, Neelakantan P. Cone-beam computed tomographic and histological investigation of regenerative endodontic procedure in an immature mandibular second premolar with chronic apical abscess, Journal of Investigative and Clinical Dentistry 2018; 9(4): article no. e12352-article no. e12352 doi:10.1111/jicd.12352
REN C, McGrath CPJ, Jin L, Zhang C, Yang Y. The effectiveness of low-level laser therapy as an adjunct to non-surgical periodontal treatment: a meta-analysis, Journal of Periodontal Research 2017; 52(1): 8-20 doi:10.1111/jre.12361
Panduwawala Kankanamalage CPP, Zhan X, Dissanayaka WL, Samaranayake LP, Jin L, Zhang C. In vivo periodontal tissue regeneration by periodontal ligament stem cells and endothelial cells in three-dimensional cell sheet constructs, Journal of Periodontal Research 2017; 52: 408-418 doi:10.1111/jre.12405
Zhu S, Wang PL, Liao C, Yang Y, YUAN C, WANG S, Dissanayaka WL, Heng BCA, Zhang C. Transgenic expression of ephrinB2 in periodontal ligament stem cells (PDLSCs) modulates osteogenic differentiation via signaling crosstalk between ephrinB2 and EphB4 in PDLSCs and between PDLSCs and pre-osteoblasts within co-culture, Journal of Periodontal Research 2017; 52(3): 562-573 doi:10.1111/jre.12424
Heng BCA, Zhang C, Deng X, Xiao Y, Pisciotta A, Kidwai F, Mitsladis TA. Biomedical Applications of Dental and Oral-Derived Stem Cells, Stem Cells International 2017; 2017: **:1-2 doi:10.1155/2017/**
Heng BCA, GONG T, Wang S, Lim LW, Wu W, Zhang C. Decellularized Matrix Derived from Neural Differentiation of Embryonic Stem Cells Enhances the Neurogenic Potential of Dental Follicle Stem Cells, Journal of Endodontics 2017; 43(3): 409-416 doi:10.1016/j.joen.2016.10.033
ZOU T, Dissanayaka WL, Jiang S, Wang S, Heng BCA, Huang X, Zhang C. Semaphorin 4D Enhances Angiogenic Potential and Suppresses Osteo-/Odontogenic Differentiation of Human Dental Pulp Stem Cells, Journal of Endodontics 2017; 43: 297-305 doi:10.1016/j.joen.2016.10.019
XU J, Zhu S, Heng BCA, Dissanayaka WL, Zhang C. TGF-β1-induced differentiation of SHED into functional smooth muscle cells, Stem Cell Research & Therapy 2017; 8(10): 10:1-10 doi:10.1186/s13287-016-0459-0
Ye X, Zhang C. Effects of Hyperlipidemia and Cardiovascular Diseases on Proliferation, Differentiation and Homing of Mesenchymal Stem Cells, Current Stem Cell Research & Therapy 2017; 12(5): 377-387 doi:10.2174/**X12666**5
Seneviratne CJ, Suriyanarayanan T, Swarup S, Chia KHB, Nagarajan N, Zhang C. Transcriptomics Analysis Reveals Putative Genes Involved in Biofilm Formation and Biofilm-associated Drug Resistance of Enterococcus faecalis, Journal of Endodontics 2017; 43: 949-955 doi:10.1016/j.joen.2017.01.020
XU J, GONG T, Heng BCA, Zhang C. A systematic review: differentiation of stem cells into functional pericytes, The FASEB Journal 2017; 31: 1775-1786 doi:10.1096/fj.RRR
LI M, Zhang C, Jin L, Matsuo K, Yang Y. Porphyromonas gingivalis lipopolysaccharide regulates ephrin/Eph signalling in human periodontal ligament fibroblasts, Journal of Periodontal Research 2017; 52: 913-921 doi:10.1111/jre.12463
LIAO C, Cheng T, WANG S, Zhang C, Jin L, Yang Y. Shear stress inhibits IL-17A-mediated induction of osteoclastogenesis via osteocyte pathways, Bone 2017; 101: 10-20 doi:10.1016/j.bone.2017.04.003
Liao C, Zhang C, Yang Y. Pivotal roles of Interleukin-17 as the Epicenter of Bone Loss Diseases, Current Pharmaceutical Design 2017; 23(41): 6302-6309 doi:10.2174/**66**0
LI X, Luo W, Ng TC, Leung PC, Zhang C, Leung CFK, Jin L. Nanoparticle-encapsulated baicalein markedly modulates pro-inflammatory response in gingival epithelial cells, Nanoscale 2017; 9: 12897-12907 doi:10.1039/C7NR02546G
Wong AWY, Zhang S, Li SKY, Zhang C, Chu CH. Clinical studies on core-carrier obturation: A systematic review and meta-analysis, BMC Oral Health 2017; 17(1): article no. 167-article no. 167 doi:10.1186/s12903-017-0459-1
Xu WL, Jiang S, Chen C, Ye YU, Chen J, Heng BCA, Jiang Q, Wu B, Ding Z, Zhang C. Systemically Transplanted Bone Marrow–derived Cells Contribute to Dental Pulp Regeneration in a Chimeric?Mouse?Model, Journal of Endodontics 2016; 42(2): 263-268 doi:10.1016/j.joen.2015.10.007
Heng BCA, Lim LW, Wu W, Zhang C. An Overview of Protocols for the Neural Induction of Dental and Oral Stem Cells In Vitro., Tissue Engineering Part B 2016; 22(3): 220-250 doi:10.1089/ten.teb.2015.0488
GONG T, Heng BCA, Lo ECM, Zhang C. Current Advance and Future Prospects of Tissue Engineering Approach to Dentin/Pulp Regenerative Therapy, Stem Cells International 2016; 2016: article no. **-article no. ** doi:10.1155/2016/**
Heng BCA, Zhu S, XU J, YUAN C, GONG T, Zhang C. Effects of decellularized matrices derived from periodontal ligament stem cells and SHED on the adhesion, proliferation and osteogenic differentiation of human dental pulp stem cells in vitro, Tissue and Cell 2016; 48: 133-143 doi:10.1016/j.tice.2015.12.004
LI X, Wong CH, Ng TW, Zhang C, Leung KCF, Jin L. The spherical nanoparticle-encapsulated chlorhexidine enhances anti-biofilm efficiency through an effective releasing mode and close microbial interactions, International Journal of Nanomedicine 2016; 11: 2471-2471 doi:10.2147/IJN.S105681
Deng Z, Wang S, Heng BCA, YUAN C, Zhang C. Enterococcus faecalis promotes osteoclast differentiation within an osteoblast/osteoclast co-culture system, Biotechnology Letters 2016; 38: 1443 doi:10.1007/s10529-016-2142-z
Jiang S, Zhang C, Wu H. Partial pulpotomy of immature teeth with apical periodontitis using bioceramics and mineral trioxide aggregate: a report of three cases, The Chinese Journal of Dental Research 2016; 19(2): 115-120 doi:10.3290/j.cjdr.a36182
YUAN C, Wang P, Zhu S, ZOU T, Wang S, XU J, Heng BCA, Diogenes A, Zhang C. EphrinB2 Stabilizes Vascularlike Structures Generated by Endothelial Cells and Stem Cells from Apical Papilla, Journal of Endodontics 2016; 42(9): 1362-1370 doi:10.1016/j.joen.2016.05.012
REN C, McGrath CPJ, Jin L, Zhang C, Yang Y. Effect of diode low-level lasers on fibroblasts derived from human periodontal tissue: a systematic review of in vitro studies, Lasers in Medical Science 2016; 31(7): 1493-1510 doi:10.1007/s10103-016-2026-4
Wong AWY, Zhang S, Zhang C, Chu CH. Perceptions of single-visit and multiple-visit endodontic treatment: a survey of endodontic specialists and general dentists in Hong Kong, Journal of Investigative and Clinical Dentistry 2016; 7(3): 263-271 doi:10.1111/jicd.12154
She CML, Cheung GSP, Zhang C. Long-Term Follow-Up of a Revascularized Immature Necrotic Tooth Evaluated by CBCT, Case Reports in Dentistry 2016; 2016: article no. **-article no. ** doi:10.1155/2016/**
Heng Boon Chin, Ye Xin, Liu Yuan, Dissanayaka Waruna Lakmal, Cheung Gary Shun Pan, Zhang Chengfei. Effects of recombinant overexpression of Bcl2 on the proliferation, apoptosis, and osteogenic/odontogenic differentiation potential of dental pulp stem cells, Journal of Endodontics 2016; 42(4): 575-583 doi:10.1016/j.joen.2016.01.013
LI X, Pang KY, Ng TW, Leung PC, Zhang C, Leung KCF, Jin L. Cellular Interactions and Formation of an Epithelial “Nanocoating-Like Barrier” with Mesoporous Silica Nanoparticles, Nanomaterials 2016; 6: 192-192 doi:10.3390/nano**
Mei L, Ito L, Zhang C, Lo ECM, Chu CH. Effect of laser irradiation on the fluoride uptake of silver diamine fluoride treated dentine, Lasers in Medical Science 2015; doi:10.1007/s10103-014-1521-8
Dissanayaka WL, Hargreaves KM, Jin L, Samaranayake LP, Zhang C. The interplay of dental pulp stem cells and endothelial cells in an injectable peptide hydrogel on angiogenesis and pulp regeneration in vivo, Tissue Engineering Part A 2015; 21(3-4): 550-563 doi:10.1089/ten.tea.2014.0154
YUAN C, Wang P, Dissanayaka WL, Green DW, Tong EH, Jin L, Zhang C. Coculture of stem cells from apical papilla and human umbilical vein endothelial cell under hypoxia increases the formation of three-dimensional vessel-like structures in vitro, Tissue Engineering Part A: Tissue Engineering 2015; 21(5-6): 1163-1172 doi:10.1089/ten.tea.2014.0058
Li D, Jiang SM, Yin X, Chang JWW, Ke J, Zhang C. Efficacy of Needle, Ultrasonic, and Endoactivator Irrigation and Photon-Induced Photoacoustic Streaming in Removing Calcium Hydroxide from the Main Canal and Isthmus: An In Vitro Micro-Computed Tomography and Scanning Electron Microscopy Study, Photomedicine and Laser Surgery 2015; 33(6): 330-337 doi:10.1089/pho.2015.3903
Jiang S, Huang X, Zhang C, Cai Z, Zou T. Morphological and proteomic analyses of the biofilms generated by streptococcus mutans isolated from caries-active and caries-free adults, Journal of Dental Sciences 2015; 10(2): 206-215 doi:10.1016/j.jds.2014.09.001
Wong AWY, Zhu X, Zhang S, Li SKY, Zhang C, Chu CH. Treatment time for non-surgical endodontic therapy with or without a magnifying loupe, BMC Oral Health 2015; 15: article no. 40-article no. 40 doi:10.1186/s12903-015-0025-7
Wang S, Liu K, Seneviratne CJ, Li XC, Cheung GSP, Jin L, Chu CH, Zhang C. Lipoteichoic acid from an Enterococcus faecalis clinical strain promotes TNF-α expression through the NF-κB and p38 MAPK signaling pathways in differentiated THP-1 macrophages, Biomedical Reports 2015; 3(5): 697-702 doi:10.3892/br.2015.495
Wang Y, Zhu X, Zhang C. Pulp Revascularization on Permanent Teeth with Open Apices in a Middle-aged Patient, Journal of Endodontics 2015; 41: 1571-1575 doi:10.1016/j.joen.2015.04.022
Bhoj M, Zhang C, Green DW. A First Step in De Novo Synthesis of a Living Pulp Tissue?Replacement Using Dental Pulp MSCs and Tissue Growth Factors, Encapsulated within a Bioinspired Alginate?Hydrogel, Journal of Endodontics 2015; 41: 1100-1107 doi:10.1016/j.joen.2015.03.006
WANG S, Deng Z, Seneviratne CJ, Cheung GSP, Jin L, Zhao B, Zhang C. Enterococcus faecalis promotes osteoclastogenesis and semaphorin 4D expression, Innate Immunity 2015; 21: 726-735 doi:10.1177/**93162
Zhu J, Li X, Zhu F, Chen L, Zhang C, McGrath CPJ, He F, Xiao Y, Jin L. Multiple tooth loss is associated with vascular cognitive impairment in subjects with acute ischemic stroke, Journal of Periodontal Research 2015; 50: 683-688 doi:10.1111/jre.12251
Chan ELK, Zhang C, Cheung GSP. Cytotoxicity of a novel nano-silver particle endodontic irrigant, Clinical, Cosmetic and Investigational Dentistry 2015; 7: 65-74 doi:10.2147/CCIDE.S68874
Zhou X, Jiang S, Wang X, WANG S, Zhu X, Zhang C. Comparison of dentinal and apical crack formation caused by four different nickel-titanium rotary and reciprocating systems in large and small canals, Dental Materials Journal 2015; 34: 903-909 doi:10.4012/dmj.2015-197
Zhu Lifang, Dissanayaka Waruna Lakmal, Green David William, Zhang Chengfei. Stimulation of EphB2/ephrin-B1 signalling by tumour necrosis factor alpha in human dental pulp stem cells, Cell Proliferation 2015; 48(2): 231-238 doi:10.1111/cpr.12172
Dissanayaka Waruna Lakmal, Zhu Lifang, Hargreaves Kenneth M., Jin Lijian, Zhang Chengfei. In Vitro Analysis of Scaffold-free Prevascularized Microtissue Spheroids Containing Human Dental Pulp Cells and Endothelial Cells, Journal of Endodontics 2015; 41(5): 663-670 doi:10.1016/j.joen.2014.12.017
Wong AWY, Zhang S, Li SKY, Zhu X, Zhang C, Chu CH. Incidence of post-obturation pain after single-visit versus multiple-visit non-surgical endodontic treatments, BMC Oral Health 2015; 15(1): article no. 96-article no. 96 doi:10.1186/s12903-015-0082-y
Wong AWY, Tsang CSC, Zhang S, Li KY, Zhang C, Chu CH. Treatment outcomes of single-visit versus multiple-visit non-surgical endodontic therapy: A randomised clinical trial, BMC Oral Health 2015; 15: article no. 162-article no. 162 doi:10.1186/s12903-015-0148-x
Mei L, Ito L, Chu CH, Lo ECM, Zhang C. Prevention of dentine caries using silver diamine fluoride application followed by Er:YAG laser irradiation: an in vitro study, Lasers in Medical Science 2014; 29(6): 1785-1791 doi:10.1007/s10103-013-1329-y
Chamila Prageeth Pandula PK, Samaranayake LP, Jin L, Zhang C. Periodontal ligament stem cells: an update and perspectives, Journal of Investigative and Clinical Dentistry 2014; 5(2): 81-90 doi:10.1111/jicd.12089
Panduwawala KCPP, Samaranayake LP, Jin L, Zhang C. Human umbilical vein endothelial cells synergize osteo/odontogenic differentiation of periodontal ligament stem cells in 3D cell sheets, Journal of Periodontal Research 2014; doi:10.1111/jre.12107
Wong AWY, Zhang C, Chu CH. A systematic review of nonsurgical single-visit versus multiple-visit endodontic treatment, Clinical, Cosmetic and Investigational Dentistry 2014; 6: 45-56 doi:10.2147/CCIDE.S61487
Yan M, Wu J, Yu Y, Wang Y, Xie L, Zhang G, Yu J, Zhang C. Mineral trioxide aggregate promotes the odonto/osteogenic differentiation and dentinogenesis of stem cells from apical papilla via nuclear factor kappa B signaling pathway, Journal of Endodontics 2014; 40: 640-647 doi:10.1016/j.joen.2014.01.042
Zhang L, Liao C, Lu J, Zhang C, Yang Y. Effects of tension force on proliferation and differentiation of human periodontal ligament cells induced by lipopolysaccharides, Journal of Biosciences and Medicines 2014; 2: 13-19 doi:10.4236/jbm.2014.23003
Zhu X, Wang Y, LIU Y, Huang GT-J, Zhang C. Immunohistochemical and histochemical analysis of newly formed tissues in root canal space transplanted with dental pulp stem cells plus platelet-rich plasma, Journal of Endodontics 2014; 40(10): 1573-1578 doi:10.1016/j.joen.2014.05.010
Guo H, Gao C, Zhang C, Zheng S, Yue L. Morphology of bacterial flora in root canals associated with apical abscesses, Chinese Medical Journal 2014; 127(18): 3254-3258 doi:10.3760/cma.j.issn.0366-6999.**
Dissanayaka W. L., Zhu L., Hargreaves K. M., Jin L., Zhang C.. Scaffold-free prevascularized microtissue spheroids for pulp regeneration, Journal of Dental Research 2014; 93(12): 1296-1303 doi:10.1177/0040
Zhan X, Zhang C, Dissanayaka WL, Cheung GSP, Jin L, Yang Y, Yan F, Tong EHY. Storage media enhance osteoclastogenic potential of human periodontal ligament cells via RANKL-independent signaling, Dental Traumatology 2013; doi:10.1111/j.1600-9657.2012.01138.x
Du Y, Lee AHC, Zhang C. Mandibular first premolar with four canals, Journal of Investigative and Clinical Dentistry 2013; 4: 64-66 doi:10.1111/j.2041-1626.2012.00127.x
Li X, Zhu XF, Zhang C, Catho PP, Seneviratne CJ, SHEN SH. Endodontic bacteria from primary and persistent endodontic lesions in Chinese patients as identified by cloning and 16S ribosomal DNA gene sequencing, Chinese Medical Journal 2013; 126(4): 634-639 doi:10.3760/cma.j.issn.0366-6999.**
Li X, Tse HF, Yiu KH, Zhang C, Jin L. Periodontal therapy decreases serum levels of adipocyte fatty acid-binding protein in systemically healthy subjects: a pilot clinical trial, Journal of Periodontal Research 2013; 48: 308-314 doi:10.1111/jre.12009
Li X, Lan HY, Huang XR, Zhang C, Jin L. Expression profile of macrophage migration-inhibitory factor in human gingiva and reconstituted human gingival epithelia stimulated by Porphyromonas gingivalis lipopolysaccharide, Journal of Periodontal Research 2013; 48(4): 527-532 doi:10.1111/jre.12035
Seneviratne CJ, Yip WY, Chang JWW, Zhang C, Samaranayake LP. Effect Of Culture Media And Nutrients On Biofilm Growth Kinetics Of Laboratory And Clinical Strains Of Enterococcus Faecalis, Archives of Oral Biology 2013; doi:10.1016/j.archoralbio.2013.06.017
Zhu XF, Yin XZ, Chang JWW, Wang YU, Cheung GSP, Zhang C. Comparison Of The Antibacterial Effect And Smear Layer Removal Using Photon-initiated Photoacoustic Streaming Aided Irrigation Versus A Conventional Irrigation In Single-rooted Canals: An In Vitro Study, Photomedicine And Laser Surgery 2013; 31 doi:10.1089/pho.2013.3515
Zhu W., Zhu X., Huang G. T J, Cheung G. S P, Dissanayaka W. L., Zhang C.. Regeneration of dental pulp tissue in immature teeth with apical periodontitis using platelet-rich plasma and dental pulp cells, International Endodontic Journal 2013; 46(10): 962-970 doi:10.1111/iej.12087
Wang QQ, Zhang CF, Chu CH, Zhu XF. Prevalence of Enterococus faecalis in saliva and filled root canals of teeth associated with apical periodontitis, International Journal of Oral Science 2012; 4(1): 19-23 doi:10.1038/ijos.2012.17
Wang W, Zeng X, Zhang C, Yang Y. Malocclusions in Xia Dynasty in China, Chinese Medical Journal 2012; 125(1): 119-122 doi:10.3760/cma.j.issn.0366-6999.2012.01.022
Dissanayaka WL, Zhan X, Zhang C, Hargreaves KM, Jin L, Tong EHY. Coculture of dental pulp stem cells with endothelial cells enhances osteo-/odontogenic and angiogenic potential in vitro, Journal of Endodontics 2012; 38(4): 454-463 doi:10.1016/j.joen.2011.12.024
Bao XD, Yao N, Gao HJ, Zhang C, Yue L. Disinfection effects of MTAD on apical isthmus of the root canal system: a scanning electron microscopic evaluation, 北京大學學報(醫學版) 2012; 44(1): 34-38 doi:10.3969/j.issn.1671-167X.2012.01.007
Wang Z, Jiang T, Sauro S, Wang Y, Xing W, Liang S, Sa Y, Zhang C, Shen Y, Haapasalo M. Nerve-targeted desensitizing toothpastes occlude dentin tubules and induce mineral precipitation, American Journal of Dentistry 2012; 25(1): 26-30
Ma J, Al-Ashaw AJ, Shen Y, Yuan G, Yang Y, Zhang C, Haapasalo M. Efficacy of proTaper universal rotary retreatment system for gutta-percha removal from oval root canals: a micro-computed tomography study, Journal of Endodontics 2012; 38(11): 1516-1520 doi:10.1016/j.joen.2012.08.001
Zhu X, Zhang C, Huang GT-J, Cheung GSP, Dissanayaka WL, Zhu W. Transplantation of dental pulp stem ells and platelet-rich plasma for pulp regeneration, Journal of Endodontics 2012; 38(12): 1604-1609
Yao N, Zhang C, Chu CH. Effectiveness of photoactivated disinfection (PAD) to kill Enteroccus faecalis in planktonic solution and in an infected tooth model, Photomedicine and Laser Surgery 2012; 30(12): 699-704 doi:10.1089/pho.2011.3216
Zhu Xiaofei, Zhang Chengfei, Huang George T J, Cheung Gary S P, Dissanayaka Waruna Lakmal, Zhu Wenhao. Transplantation of dental pulp stem cells and platelet-rich plasma for pulp regeneration, Journal of Endodontics 2012; 38(12): 1604-1609 doi:10.1016/j.joen.2012.09.001
Wang Y, Dong L, Bi Q, Ge X, Zhang X, Wu D, Fu J, Zhang C, Wang C, Li S. Beyond antiangiogenesis: Intratumorally injected bevacizumab plays a cisplatin-sensitizing role in squamous cell carcinomas in mice, Chemotherapy 2011; 57(3): 244-252 doi:10.1159/
Zhang C, Chan AWK, Dissanayaka WL. Mineral trioxide aggregate repair of lateral root perforation using intentiional replantation and bone grafting, Hong Kong Dental Journal 2011; 8(1): 51-55
Fan R, Sun B, Zhang CF, Lü YL, Xuan W, Wang QQ, Yin XZ. Receptor activator of nuclear factor kappa B ligand and osteoprotegerin expression in chronic apical periodontitis: Possible association with inflammatory cells, Chinese Medical Journal 2011; 124(14): 2162-2166 doi:10.3760/cma.j.issn.0366-6999.2011.14.015
Dissanayaka WL, Zhu X, Zhang C, Jin L. Characterization of dental pulp stem cells isolated from canine premolars, The Journal of Endodontics 2011; 37(8): 1074-1080 doi:10.1016/j.joen.2011.04.004
Ma Z, Wang Y, Zhu X, Zhang C, Li S, Jin L, Shen Y, Haapasalo M. Role of polymorphonuclear neutrophils in the clearance of enterococcus faecalis derived from saliva and infected root canals, Journal of Endodontics 2011; 37(3): 346-352 doi:10.1016/j.joen.2010.11.033
Lin X, Wu W, Zhang C, Lo EC, Chu CH, Dissanayaka WL. Prevalence and distribution of developmental enamel defects in children with cerebral palsy in Beijing, China, International Journal of Paediatric Dentistry 2011; 21(1): 23-28 doi:10.1111/j.1365-263X.2010.01075.x
Zhang C. 牙体牙髓病临床问题解析Ⅷ，牙根尖三分之一的生物學特點及臨床意義, 中華口腔醫學雜誌 2011; 46(9): 567-570 doi:10.3760/cma.j.issn.1002-0098.2011.09.015
Zheng CY, Pan J, Wang L, Zhang CF. Effects of hydrogen peroxide-containing bleaching on cariogenic bacteria and plaque accumulation, The Chinese Journal of Dental Research 2011; 14(1): 47-52
Chu CH, Zhang CF, Jin LJ. Treating a maxillary midline diastema in adult patients: A general dentist's perspective, Journal of the American Dental Association 2011; 142(11): 1258-1264 doi:10.14219/jada.archive.2011.0110
Du Y, Soo I, Zhang CF. A case report of six canals in a maxillary first molar., The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) 2011; 14(2): 151-153
Wang Y, Cheung GSp, Xu X, Zhao S, Zhang C. The Effect of Cultured Autologous Periodontal Ligament Cells on the Healing of Delayed Autotransplanted Dog's Teeth, Journal of Endodontics 2010; 36(2): 264-267 doi:10.1016/j.joen.2009.09.014
Ma Z, Xu Z, Zhang C. 奎納克林對順鉑抑制口腔鱗癌細胞系SCC-VII體內外生長作用的影響, 山東醫藥 2010; 50(19): 45-46
Zhu X, Wang Q, Zhang C, Cheung GSP, Shen Y. Prevalence, phenotype, and genotype of enterococcus faecalis isolated from saliva and root canals in patients with persistent apical periodontitis, Journal of Endodontics 2010; 36(12): 1950-1955 doi:10.1016/j.joen.2010.08.053
Wang Y, Dong L, Bi Q, Li X, Wu D, Ge X, Zhang X, Fu J, Zhang C, Wang C, Li S. Investigation of the efficacy of a bevacizumab-cetuximabcisplatin regimen in treating head and neck squamous cell carcinoma in mice, Targeted Oncology 2010; 5(4): 237-243 doi:10.1007/s11523-010-0164-3
Zhang S, Wang QQ, Zhang C, Soo I. Identification of dominant pathogens in periapical lesions associated with persistent apical periodontitis, The Chinese Journal of Dental Research 2010; 13(2): 115-121
Zhao X, Wang S, Zhang C. Root resection by Er:YAG laser: A scanning electron microscope study, 華西口腔醫學雜誌 2010; 28(5): 526-528 doi:10.3969/j.issn.1000-1182.2010.05.018
Li Y, Zhang C, Wang X. Microbiological study of infected root canals: a review, 口腔醫學硏究 2010; 26(3): 437-439
Wang Q, Yao N, Zhao X, Zhang C. Antimicrobial effect of photo-activated disinfection therapy in vitro and in vivo studies, 國際口腔醫學雜誌 2010; 37(4): 392-395 doi:10.3969/j.issn.1673-5749.2010.04.005
Zhu W, Wang S, Zhang C. A clinical study on cavities' preparation of subgingival wedge-shape defects using Er: YAG laser, Journal of Modern Stomatology 2010; 24(1): 21-23 doi:10.3969/j.issn.1003-7632.2010.01.007
Yin X, Cheung GSP, Zhang C, Masuda YM, Kimura Y, Matsumoto K. Micro-computed Tomographic Comparison of Nickel-Titanium Rotary versus Traditional Instruments in C-Shaped Root Canal System, Journal of Endodontics 2010; 36(4): 708-712 doi:10.1016/j.joen.2010.01.003
Chi X, Zhang C, Cao C. Residual dentin thickness in upper anterior teeth after root canal preparation, Journal of Modern Stomatology 2009; 23(3): 239-241
Zhou X, Zhang C, Yin X, Ma Q. Comparative study of cutting efficiency of three instrumentation techniques in C-shaped canals, Journal of Practical Stomatology 2009; 25(1): 99-102
Huang J, Zhang C. One-root molars: case report, Journal of Oral Science Research 2009; 25(1): 89-89
Yan H, Ma C, Ren M, Yin X, Zhang C, Wei Y, Dong X. K3 NiTi file negotiation of resinfying root canal and evalulation of its damage, Journal of Nurses Training 2009; 24(20): 1899-1900
Ding RY, Cheung GSp, Chen J, Yin XZ, Wang QQ, Zhang CF. Pulp Revascularization of Immature Teeth With Apical Periodontitis: A Clinical Study, Journal of Endodontics 2009; 35(5): 745-749 doi:10.1016/j.joen.2009.02.009
Wang Qq, Zhang Cf, Yin Xz. Evaluation of the Bactericidal Effect of Er,Cr:YSGG, and Nd:YAG Lasers in Experimentally Infected Root Canals, Journal of Endodontics 2007; 33(7): 830-832 doi:10.1016/j.joen.2007.03.017
Chang J, Sonoyama W, Wang Z, Jin Q, Zhang C, Krebsbach PH, Giannobile W, Shi S, Wang CY. Noncanonical Wnt-4 signaling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK, Journal of Biological Chemistry 2007; 282(42): 30938-30948 doi:10.1074/jbc.M
Matsumoto K, Wang X, Zhang C, Kinoshita JI. Effect of a novel Er:YAG laser in caries removal and cavity preparation: A clinical observation, Photomedicine and Laser Surgery 2007; 25(1): 8-13 doi:10.1089/pho.2006.2020
Zhang C, Wang X, Kinoshita JI, Zhao B, Toko T, Kimura Y, Matsumoto K. Effects of KTP laser irradiation, diode laser, and LED on tooth bleaching: A comparative study, Photomedicine and Laser Surgery 2007; 25(2): 91-95 doi:10.1089/pho.2006.2025
He BZ, Yin XZ, Zhang CF. Clinical evaluation of the effect of angulation apical X-rays and the X-rays with file in diagnosing multiple canals in mandibular anterior teeth and premolars, Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2006; 41(3): 160-163
Wang X, Zhang C, Matsumoto K. In vivo study of the healing processes that occur in the jaws of rabbits following perforation by an Er,Cr:YSGG laser, Lasers in Medical Science 2005; 20(1): 21-27 doi:10.1007/s10103-005-0329-y
Zhang CF, Wang JD. Root canal obturation: techniques, problems and management, Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2004; 39(3): 254-257
Zhang CF, Wang JD. Endodontics: special problems and management, Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2004; 39(4): 329-332
Zhang CF, Wang JD. The conception of modern root canal therapy, Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2004; 39(1): 77-80
Zhang CF, Wang JD. Endodontic instrumentation: techniques, problems and management, Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2004; 39(2): 162-165
Zhang CF, Ding RY, Yin XZ, Zhao BH, Lin QG. Location and negotiation of second mesiobuccal canals in maxillary molars, Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology. 2003; 38(2): 86-88
Zhang C, Lin Q, Zhao B. The combined occluding effect of fluor protector and Nd:YAG laser irradiation on human dentinal tubules, Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2001; 36(2): 105-107
Wang X, Zhang C, Lin Q. Alteration of immunological properties of bacterial lipopolysaccharide by calcium hydroxide treatment, Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2001; 36(6): 417-420
Harashima T, Takeda FH, Zhang C, Kimura Y, Matsumoto K. Effect of argon laser irradiation on instrumented root canal walls, Endodontics and Dental Traumatology 1998; 14(1): 26-30
Zhang C, Kimura Y, Matsumoto K, Harashima T, Zhou H. Effects of pulsed Nd:YAG laser irradiation on root canal wall dentin with different laser initiators, Journal of Endodontics 1998; 24(5): 352-355
Zhang C, Kimura Y, Nakamura Y, Matsumoto K. Light and scanning electron microscopic observation of human dental occlusal enamel treated by pulsed Nd:YAG laser with fluoride, Lasers in the Life Sciences 1998; 8(1): 13-26
Zhang C, Matsumoto K, Kimura Y, Harashima T, Takeda FH, Zhou H. Effects of CO 2 laser in treatment of cervical dentinal hypersensitivity, Journal of Endodontics 1998; 24(9): 595-597 doi:10.1016/S0099-2399(98)80117-9
Hong L, Wu M, Zhang C. Using Nd-YAG laser to desensitize the hypersensitive dentine in preparing the abutment teeth for removable partial dentures prosthesis, Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 1997; 32(1): 28-30
Zhang C, Lin Q, Cao C. Experimental study on uptake of fluoride by dentin after pulsed Nd:YAG laser irradiation, Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 1996; 31(3): 140-142
Conference Paper
Dissanayaka WL, Zhang C. Scaffold-based and Scaffold-free Strategies in Dental Pulp Regeneration, Journal of Endodontics 2020; 46(9, suppl.): S81-S89 doi:10.1016/j.joen.2020.06.022
YI B, Dissanayaka WL, Zhang C. Growth Factors and Small-molecule Compounds in Derivation of Endothelial Lineages from Dental Stem Cells, Journal of Endodontics 2020; 46(9, suppl.): S63-S70 doi:10.1016/j.joen.2020.06.024
Chopra H, Han Y, Pan Y, Guan XY, Kwong DLW, Zhang C, Pow EHN. PDLCs and EPCs synergistically enhance osseointegration in irradiated rabbit bone, IADR/AADR/CADR 2019 General Session & Exhibition 2019; 98(Spec ISS A): no. O231-no. O231
Liao C, Hua Y, Zhang C, Jin L, Yang Y. IL-17 enhances osteogenic differentiation of MSCs in 3D-printed PCL scaffold, Journal of Dental Research (Spec Issue) 2019; 98(Spec Iss A): abstract no. 3595-abstract no. 3595
Jiang S, Heng BC, Zhang C. Small Molecules Enhance Neurogenic Differentiation Of Dental-derived Adult Stem Cells, IADR/AADR/CADR 2019 General Session & Exhibition 2019; 98(Spec Iss A): abstract ID 3256-abstract ID 3256
Zhang JJ, Zhang C, Chu CH. Enhanced Osteogenic Differentiation by cAMP-loaded Layer-by-layer Self-assembly on Gelatin-Based Hydroxyapatite, Journal of Dental Research (Spec Issue) 2019; 98(Spec ISS A): article no. 1553-article no. 1553
Zhang J, Zhang C, Chu CH. Upregulating Odonto/Osteogenic-differentiation of Dental Stem Cells by cAMP-loaded Layer-by-layer Self-assembly, General Session of the IADR cum IADR Pan European Regional Congress 2018;
Wang Y, Liu HN, Zhen Z, Yiu KH, Tse HF, Zhang C, Pelekos G, Jin L. Periodontal treatment increases circulating EPC counts in patients with T2DM, Journal of Dental Research (Spec Issue) 2018; 97(Spec Iss B): no. 1114-no. 1114
Liao C, Zhang C, Jin L, Yang Y. IL-17 alters MSC cell niche towards osteogenesis cooperated with osteocytes, Journal of Dental Research (Spec Issue) 2018; 97(Spec Iss B): abstract no. 2286-abstract no. 2286
Zhang C. Interaction Between Dental Pulp Stem Cells and Endothelial Cells During Postnatal Vascular Remodeling and Maturation, Annual Meeting & Exhibition of the AADR and Annual Meeting of the CADR 2018;
Zhang C, Dissanayaka WL. The role of vasculature engineering in dental pulp regeneration, Joint Scientific Symposium: Current and Future Challenges in Dentistry 2017;
Dissanayaka WL, Zhang C. Endothelial differentiation of dental stem cells in a three-dimensional microtissue culture system, ISSCR International Symposium: Translational Opportunities in Stem Cell Research, Basel 2017 2017; 98-98
Li X, Luo W, Ng TW, Leung PC, Zhang C, Leung KCF, Jin L. Mesoporous silica nanoparticle-encapsulated Scutellaria baicalensis as a promising immuno-inflammatory modulator for periodontal care, International Conference on Porphyromonas gingivalis and Related Species in Oral and Systemic Diseases 2017;
Liao C, Zhang C, Jin L, Yang Y. IL-17A and shear stress modulate osteoclastogenesis/osteogenesis in bone cells, IADR/AADR/CADR 2017 General Session & Exhibition 2017;
LI M, Zhang C, Yang Y. Effects of Lipopolysaccharide on Human Periodontal Ligament Fibroblasts under Mechanical Compression through EphB4-ephrinB2 Signalling, American Association of Orthodontists Annual Session, 2017 2017;
Zhang J, Zhang C, Chu CH. cAMP signaling up-regulates odonto/osteogenic differentiation of apical papilla-derived stem cells, International Association for Dental Research South East Asian Division Meeting (IADR-SEA) 2017; S0126-S0126
Zhang C, Xu J. Stem cells from human exfoliated deciduous teeth share similar functional properties with pericytes, IADR/AADR/CADR 2017 General Session & Exhibition 2017; abstract no. 2278-abstract no. 2278
Zhang C. Reasons of Root Canal Treatment Failure, China International Dental Exhibition and Scientific Conference 2017;
Dissanayaka WL, Zhang C. The Role of Vasculature Engineering in Dental Pulp Regeneration, Journal of Endodontics 2017; 43: S102-S106 doi:10.1016/j.joen.2017.09.003
Zhang C. Enhancement of Dental Pulp Regeneration by the Combination of DPSCs Transfected with VEGF and SDF-1Α, Annual Meeting of the International Society for Stem Cell Research, ISSCR 2017 2017; 500-501
Zhang C. Pulp regeneration and vital pulp therapy, and microscopic endodontic treatment, 29th Malaysian Endodontic Society Annual Scientific Meeting and Annual General Meeting 2017;
Zhang C. The role of pre-vascularization in pulp regeneration, 2017 IADR Chinese Division Annual Meeting, Annual Conference of Fujian Stomatological Association, and Geriatric Dentistry Professional Board of Chinese Stomatological Association Annual Meeting 2017;
Zhang C. Current status and advances on Modern Root Canal Therapy, Foshan Stomatological Hospital, Training Lecture 2017;
Zhang C. Focusing on Endodontic Microsurgery, The 22nd China International Dental Exhibition & Scientific Conferene 2017;
LIAO C, Zhang C, Jin L, Yang Y. Bidirectional regulation by Interleukin-17 in osteogenesis and osteoclastogenesis., HKU Faculty of Dentistry 2017 Annual Scientific Meeting 2017;
Liao C, Zhang C, Jin L, Yang Y. Role of Interleukin-17 in bone modelling, China International Orthodontic Conference and the 16th Annual Session of Chinese Orthodontic Society, 2017 2017;
Zhang C. Standardization construction in clinical teaching process of stomatology, Nanjing Medical University, Seminar 2017;
Zhang C. Several questions worthy to be discussed of root canal therapy, Microscopic root canal therapy and new progress of nickel-titanim instrument conference, Zhengzhou Stomatologic Hospital, Zhengzhou, China 2017;
Zhang C. Diagnosis and management of vertical root fractures, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou 2017;
Zhang C. Clinical applications of regenerative endodontics, Guanghua School of Stomatology, Sun Yat-sen University Training 2017;
Zhang C. The precise control of root canal preparation, Lecture on root canal therapy, Jinan Stomatological Hospital 2017;
Yang Y, Liao C, Jin L, Zhang C. IL-17 expression and its effect on osteoclastogenesis under mechanical loading, Journal of Dental Research 2016; 95(Spec. Iss. B)
Zhang C. Regenerative Endodontics and Vital Pulp Therapy, 31st IACDE & 24th IES National Conference 2016;
Zhang C. Dual impact of lipoteichoic acids from Enterococci faecalis on osteoclastogenesis, 16th Australasian BioCeramic Symposium (ABC), 2016 2016;
Zhang C. The role of scaffolding and prevascularization in pulp regeneration, IADR Pulp Biology Regeneration Group Symposium (IADR PBRG Symposium) 2016 2016;
Zhang C. Derivation of endothelial and vascular smooth muscle cells from SHED for pulp regeneration, IADR General Session, Seoul 2016;
Zhang C. Topic: Pulp regeneration and vital pulp therapy, 31st IACDE & 24th IES National Conference Kolkata 2016 2016;
Wang S, Deng Z, Seneviratne CJ, Cheung G, Jin L, Zhang C. Enterococcus faecalis promotes RANKL-dependent TRAP-positive osteoclastogenesis and semaphorin 4D expression, Journal of Dental Research Meeting Abstracts 2015; 94(Spec. Iss. A)
Zhang C, Wang S, Deng Z, Seneviratne CJ, Cheung G, Jin L. Enterococcus facaelis attenuates osteogenesis in MC3T3-E1 cells, Journal of Dental Research Meeting Abstracts 2015; 94(Spec. Iss. A)
Li M, Zhang C, Jin L, Matsuo K, Yang Y. Influence of lipopolysaccharide on EPHRIN/EPH expression in human periodontal ligament fibroblasts, Congress of the European Orthodontic Society, EOS 2015 2015;
Liao C, Zhang C, Jin L, Matsuo K, Yang Y. Expression of EPH-EPHRIN signalling in osteocytes under mechanical loading, Congress of the European Orthodontic Society, EOS 2015 2015;
Chu CH, Wong AWY, Zhang C. Post-operative pain of single versus multiple visit non-surgical endodontic therapy, Journal of Dental Research 2015; 94(Special Issue A)
Jiang S, Li D, Zhang C. Effectiveness of sonic, ultrasonic and laser irrigation on filling materials removal in premolar root canals, Journal of Dental Research 2015; 94(Spec Iss B (SEA Division))
Zhang C. Stem cell based regeneration and bone resorption, IADR/AADR/CADR General Session 2015 2015;
Dissanayaka WL, Hargreaves K, Jin L, Zhang C. Prevascularized Three-Dimensional DPSC Constructs in Dental Pulp Regeneration, Journal of Dental Research 2014; 93(Special issue B: abstract no. 174)
Panduwawala CP, Samaranayake LP, Jin L, Zhang C. Development of Novel 3D Stem Cell Sheet for Periodontal Regeneration, Journal of Dental Research 2014; 93(Special issue B: abstract no. 1067)
Zhang C. Three-Dimensional Microtissue Spheroids of Dental Pulp Stem Cells and Endothelial Cells in Vascularised Pulp Regeneration, Annual Meeting International Society for Stem Cell Research (ISSCR) 2014; 73, abstract no. W-2099-74, abstract no. W-2099
Yang Y, Zhang L, Liao C, Lu J, Zhang C. Effects of mechanical force on proliferation and differentiation of human periodontal ligament cells, 29th Joint Annual Conference of Biomedical Science 2014;
Li M, Zhang C, Yang Y. Effects of LPS on Ephrin/Eph signaling in PDL fibroblasts, IADR/SEAADE Scientific Meeting 2014 2014;
Wang S, Liu K, Seneviratne CJ, Cheung GSP, Jin L, Zhang C. Enterococcus faecalis LTA induces TNF-α through NF-κB and p38 pathways, Journal of Dental Research 2014; 93(Spec. Iss. C)
Keung CWY, Wong AWY, Zhang C, Chu CH. Perceptions of single-visit and multiple- visit endodontic treatment in Hong Kong., Journal of Dental Research 2014; 93(Special Issue C)
Zhang C. Latest developments in endodontics, Keynote speech, Peking University 2014;
Zhu J, Li X, Zhu F, Zhang C, McGrath CPJ, Jin L. Tooth Loss and Vascular Cognitive Impairment in Acute Stroke Patients, Journal of Dental Research 2013; 92(Special Issue A: abstract no. 88)
Dissanayaka WL, Zhang C, Hargreaves K, Jin L. Peptide Hydrogel Scaffold Promotes Angiogenesis And Osteo/Odontogenic Differentiation In-Vitro, Journal of Dental Research 2013; 92(Special Issue A: abstract no. 3605)
Panduwawala KCPP, Samaranayake LP, Jin L, Zhang C. Synergistic effects of PDL stem cells/HUVECs in 3D cell sheet, Journal of Dental Research 2013; 92(Special Issue A: abstract no. 3900)
Yang Y, Zhang L, Zhang C, Zhan X. LPS promoted mechanical-loaded PDL cells' proliferation through Wnt2 pathway, 89th EOS Congress 2013 2013;
Lu J, Yang Y, Zhang C. Effects of lipopolysaccharide on cell cycling of human PDL cells, Meeting of International Association for Dental Research - Asia Pacific Region 2013; abstract no. 645-abstract no. 645
Dissanayaka WL, Hargreaves KM, Jin L, Zhang C. Scaffold-free Three-dimensional Spheroids of DPSCs/ECs in Vascularised Pulp Regeneration, Journal of Dental Research 2013; 92(Special Issue B: abstract no. 358)
Panduwawala CP, Samaranayake LP, Jin L, Zhang C. HUVECs Synergize Osteo/Odontogenic Differentiation Of PDLSCs In 3D Cell Sheets, Journal of Dental Research 2013; 92(Special Issue B: abstract no. 42)
Zhang C. Clinical procedures and case selection for pulp regeneration, 104th Annual Convention & Scientific Meeting 2013;
Zhang C. Dental pulp regeneration, School and Hospital of Stomatology, Peking University 2013;
Wong AWY, Wang Q, Zhu X, Yin X, Zhang C, Chu CH, Lo ECM. Time used in endodontic treatment with or without magnifying loupes, IADR 90th General Session & Exhibition 2012;
Dissanayaka WL, Zhang C, Hargreaves KM, Jin LJ. Synergistic actions of DPSCs and ECs in vascularising bioengineered pulp, IADR 90th General Session & Exhibition 2012;
Dissanayaka WL, Zhang C, Panduwawala KCPP. Development of prevascularized dental pulp constructs by synergistic effects of human dental pulp stem/progenitor cells and endothelial cells, Annual Meeting of the International Society for Stem Cell Research, ISSCR 2012 2012; 1: 119-119
Dissanayaka WL, Zhang C, Jin L, Hargreaves KM. ECs Enhance DPSC Properties And Therapeutic Potential In Three-dimensional Model, Journal of Dental Research 2012; 91(Special Issue C: abstract no. 168954)
Ito L, Mei L, Zhang C, Lo ECM, Chu CH. Laser effects on dentine treated with silver diamine fluoride, Journal of Dental Research 2012; 91(Special Issue C: abstract no. 168999)
Zhang L, Yang Y, Zhang C, Zhan X. LPS induces PDL cells’ proliferation with participation of Wnt2, International Dental Journal 2012; 62(suppl. 1): 79-79 doi:10.1111/j.1875-595X.2012.00136.x
Yang Y, Zhang L, Zhang C, Zhan X. Wnt2 participates in PDL cells’ proliferation under mechanical loading, International Dental Journal 2012; 62(suppl. 1): 29-29 doi:10.1111/j.1875-595X.2012.00134.x
Green DW, Zhang C, Cheung LK, Li G. Readying adult stem cells towards the clinic: incubation within cellular assemblies and sugar substrates, 2nd CUHK International Symposium on Stem Cell Biology and Regenerative Medicine 2012;
Yao N, Zhang C. A laboratory investigation of photo-activated disinfection (PAD) to enterococcus faecalis, IADR/AADR/CADR General Session and Exhibition 2011;
Zhang C, Wang H, Wang Y. PMNs' role on clearance of E. faecalis from oral cavity, IADR General Session 2011;
Dissanayaka WL, Zhang C, Jin L. Synergistic effects of endothelial and dental pulp stem cells in-vitro, IADR/SEAADE Annual Scientific Meeting, 2011 2011;
Zhang C. Endodontic problems: prevention and amnagement, China International Dental Exhibition and Scientific Conference 2011;
Wang Q, Zhang S, Wang Y, Zhang C. The dominant bacteria species in periapical endodontic lesions of persistent apical periodontits, 2009 Conjoint Scientific Sessions: Faculty of Dentistry, the University of Hong Kong and Peking University School of Stomatology 2009;
Zhu X, Wang Q, Yin X, Zhang C. Prevalence, phenotype and genotype of Enterococcus faecalis isolated in oral-rinse and root-canal samples from patients with periapical lesions after root-canal-treatment, 2009 Conjoint Scientific Sessions: Faculty of Dentistry, the University of Hong Kong and Peking University School of Stomatology 2009;
Zhu X, Wang Q, Yin X, Zhang C. Preliminary study on Enterococcus faecalis isolated from saliva and root canals, PAPF/APR 2009 2009;
Book Chapter
Dissanayaka WL, Zhang C. Dental Pulp Stem Cells and Hydrogel in Pulp Regeneration . Dental Stem Cells: Regenerative Potential. Cham: Humana Press; 2016:: 133-145.
Dissanayaka WL, Zhang C. Dental Pulp Stem Cells and Hydrogel in Pulp Regeneration . Dental Stem Cells: Regenerative Potential, Stem Cell Biology and Regenerative Medicine. Cham, Switzerland: Springer; 2016:133-145.

Honours and Awards
2019. Jiang S, Zhang C, Lo ECM, Li XC, Li X. Innovation Oral Care Award: 2019 IADR/AADR.
2017. LIAO C, Zhang C, Jin L, Yang Y. Nomination of IADR Bernard G. Sarnat Award in Craniofacial Biology, IADR/APR General Session & Exhibition. IL-17A and shear stress modulate osteoclastogenesis/osteogenesis in bone cells.: The 95th General Session of the International Association for Dental Research, Mar 22- 25, 2017, San Francisco, USA..
2016. Dissanayaka WL, ZHU L, Hargreaves KM, Jin L, Zhang C. 2016 IADR/AADR William J. Gies Award for Biomaterials and Bioengineering Research: IADR/AADR.
2016. Dissanayaka WL, ZHU L, Hargreaves KM, Jin L, Zhang C. Journal of Endodontics award for the Best Paper in Basic Science: Biology2016: American Association of Endodontists.
2016. Bhoj M, Zhang C, Green DW. 2016 Journal of Endodontics Awards (honorable mentions) articles published in JOE during the 2015 calendar year.
2016. Zhang C. The interplay of dental pulp stem cells and endothelial cells in an injectable peptide hydrogel on angiogenesis and pulp regeneration in vivo: The award of the 2016 Research Output Prize.
2015. Dissanayaka WL, Zhang C, Jin L. Research Output Award - Faculty of Dentistry 2016.
2012. Dissanayaka WL, Zhang C, Hargreaves K.M., Jin L. 2012 International Association for Dental Research (IADR)/Colgate Research in Prevention Travel Award, Igua?u, Brazil (Co- supervisor for Mr. W.L. Dissanayaka, a PhD student): IADR.

Editorships
2013: Member of JADA Editorial Board. JADA Editorial Board, Guangzhou, China, February 27.

Knowledge Exchange
01 October 2018: Dissanayaka Waruna Lakmal, Tsoi Kit Hon, Zhang Chengfei. Empowering secondary school teachers in Hong Kong with the knowledge of tooth-derived stem cells and its potential applications.
01 September 2018: Dissanayaka Waruna Lakmal, Zhang Chengfei, Tsoi Kit Hon. 2018/19 KE Impact Project Funding: KE-IP-2018/19-27: Empowering secondary school teachers in Hong Kong with the knowledge of tooth-derived stem cells and its potential applications ($70,000).
21 October 2013: Cheung Gary Shun Pan, Chang Jeffrey Wen Wei, Zhang Chengfei. Endodontic Attachment Week.

Professional Societies
07/2012: member. American Endodontic Association.
07/2012: member. International Assoiciation of Dental Research.
07/2012: member. Hong Kong dental Association.
03/2012: member. International Society of Stem Cell Research.
01/2011: member. Hong Kong Dental Association.
01/2011: member. Hong Kong Endodontic Society.
01/2011: member. International Dental Association.
01/2011: member. American Endodontic Association.
01/2010-12/2010: member. Hong Kong Endodontic Society.
01/2010-12/2010: member. International Association for Dental Research.
01/2009-12/2010: member. American Endodontic Association.
01/2009-: member. Chinese Stomatological association.

Grants
Project Title: Locally generated oxygen combined with blocking Sug1/CIITA signaling synergistically enhance allogeneic DPSCs survival and pulp tissue regeneration
Grant Type: General Research Fund (GRF)
Funding Year: 2021
Amount: HKD**
Principal Investigator: Professor Zhang, Chengfei
Co-investigator(s): Dr Dissanayaka Waruna Lakmal, Dr Jiang Shan, Dr Yuan Changyong, Dr Zou Ting
Project Title: Deciphering the optimal settings and biological functions of small molecule activators of HIF-1α stabilization in dental stem cells
Grant Type: General Research Fund (GRF)
Funding Year: 2021
Amount: HKD**
Principal Investigator: Dr Dissanayaka, Waruna Lakmal
Co-investigator(s): Dr Koohi-Moghadam Mohamad, Professor Zhang Chengfei
Project Title: Novel angiogenic and electrically conductive niche synergizing with electrical stimulation accelerates angiogenesis and neurogenesis in pulp regeneration
Grant Type: General Research Fund (GRF)
Funding Year: 2020
Amount: HKD996285
Principal Investigator: Professor Zhang, Chengfei
Co-investigator(s): Professor Zhao Yi, Dr Jiang Shan, Dr Dissanayaka Waruna Lakmal, Dr Lim Lee Wei
Project Title: The Hif-1α-SEMA4D-Plexin-B1 signaling axis regulates dental stem cells in the stabilization of vascular structures
Grant Type: General Research Fund (GRF)
Funding Year: 2019
Amount: HKD**
Principal Investigator: Dr Dissanayaka, Waruna Lakmal
Co-investigator(s): Professor Zhang Chengfei
Project Title: Bio-fabricated tissue constructs with angiogenic, neurogenic and odontogenic niches for enhancing dental pulp regeneration
Grant Type: General Research Fund (GRF)
Funding Year: 2019
Amount: HKD**
Principal Investigator: Professor Zhang, Chengfei
Co-investigator(s): Dr Bertassoni Luiz Eduardo, Dr Lim Lee Wei, Dr Dissanayaka Waruna Lakmal, Dr Jiang Shan
Project Title: Spheroids of HIF-1α-stabilized SHED as vascularization units for the treatment of peripheral tissue ischemia
Grant Type: Health and Medical Research Fund - Full Grant
Funding Year: 2019
Amount: HKD**
Principal Investigator: Dr Dissanayaka, Waruna Lakmal
Co-investigator(s): Professor Zhang Chengfei
Project Title: Small molecules-based conversion of SCAP into endothelial cells
Grant Type: National Natural Science Foundation of China (NSFC) - General Program
Funding Year: 2019
Amount: HKD690080
Principal Investigator: Professor Zhang, Chengfei
Co-investigator(s): Dr Dissanayaka Waruna Lakmal
Project Title: A novel cAMP-loaded layer-by-layer assembly to promote bone regeneration using apical papilla derived stem cells
Grant Type: Health and Medical Research Fund - Full Grant
Funding Year: 2018
Amount: HKD914520
Principal Investigator: Professor Chu, Chun Hung
Co-investigator(s): Dr Li Quanli, Dr Zhang Jing, Professor Zhang Chengfei
Project Title: Engineered neural tissue constructs using dental-derived neural stem cells to promote peripheral nerve regeneration
Grant Type: Health and Medical Research Fund - Full Grant
Funding Year: 2018
Amount: HKD**
Principal Investigator: Professor Zhang, Chengfei
Co-investigator(s): Professor Chan Ying Shing, Dr Lim Lee Wei, Dr Dissanayaka Waruna Lakmal
Project Title: Engineered tissue constructs with inbuilt perfusable microchannel networks for dental pulp regeneration
Grant Type: General Research Fund (GRF)
Funding Year: 2017
Amount: HKD**
Principal Investigator: Professor Zhang, Chengfei
Co-investigator(s): Dr Heng Boon Chin Alexis, Professor Jin Lijian, Dr Dissanayaka Waruna Lakmal, Dr Bertassoni Luiz Eduardo
Project Title: Enhancing post-implantation dental stem cell survival and angiogenesis via in vitro stabilization of HIF-1α signaling
Grant Type: General Research Fund (GRF)
Funding Year: 2017
Amount: HKD894200
Principal Investigator: Dr Dissanayaka, Waruna Lakmal
Co-investigator(s): Professor Zhang Chengfei
Project Title: Small molecule-based reprogramming of Gingival Mesenchymal Stem Cells into the neural lineage for therapeutic applications
Grant Type: Health and Medical Research Fund - Full Grant
Funding Year: 2017
Amount: HKD**
Principal Investigator: Professor Zhang, Chengfei
Co-investigator(s): Dr Heng Boon Chin Alexis, Dr Lim Lee Wei
Project Title: EphrinB2 enhances angiogenesis and anastomosis of bioengineered prevascularized dental pulp construct
Grant Type: General Research Fund (GRF)
Funding Year: 2014
Amount: HKD591200
Principal Investigator: Dr Zhang, Chengfei
Co-investigator(s): Dr Green David William, Professor Cheung Gary Shun Pan, Professor Jin Lijian
Project Title: EphrinB2 and VEGF cooperatively regulate dental pulp stem cell functions and blood vessel formation
Grant Type: National Natural Science Foundation of China (NSFC) - General Program
Funding Year: 2014
Amount: HKD916880
Principal Investigator: Dr Zhang, Chengfei
Co-investigator(s): Professor Cheung Gary Shun Pan, Professor Jin Lijian
Project Title: Does inflammation affect periodontal cell communication through Eph-ephrin under mechanical loading?
Grant Type: General Research Fund (GRF)
Funding Year: 2013
Amount: HKD606223
Principal Investigator: Dr Yang, Yanqi
Co-investigator(s): Professor Matsuo Koichi, Professor Zhang Chengfei, Professor Jin Lijian
Project Title: A randomized controlled trial of a laser-aided orthodontic treatment for patients with periodontitis
Grant Type: Health and Medical Research Fund - Full Grant
Funding Year: 2013
Amount: HKD865444
Principal Investigator: Dr Yang, Yanqi
Co-investigator(s): Professor Zhang Chengfei, Dr Chau Cheuk Man, Professor McGrath Colman, Professor Jin Lijian
Project Title: Engineering human dental pulp tissues using prevascularized microtissue spheroids constructed by dental pulp stem cells and gene-modified endothelial cells
Grant Type: General Research Fund (GRF)
Funding Year: 2012
Amount: HKD**
Principal Investigator: Dr Zhang, Chengfei
Co-investigator(s): Dr Seneviratne Chaminda Jayampath, Professor Jin Lijian, Professor Cheung Gary Shun Pan, Professor Hargreaves Kenneth M.
Project Title: Lipoteichoic acid (LTA) of pathogenic Enterococcus faecalis modulates the functional characteristics of osteoblasts and osteoclasts
Grant Type: Health and Medical Research Fund - Full Grant
Funding Year: 2012
Amount: HKD765000
Principal Investigator: Dr Zhang, Chengfei
Co-investigator(s): Professor Li Xuechen, Dr Watt Rory Munro, Professor Jin Lijian, Dr Seneviratne Chaminda Jayampath
Project Title: Bcl-2 and cMyc gene-transfected dental pulp stem cells outcompete bone marrow-derived cells in dental pulp regeneration
Grant Type: National Natural Science Foundation of China (NSFC) - General Program
Funding Year: 2012
Amount: HKD879200
Principal Investigator: Dr Zhang, Chengfei
Co-investigator(s): Dr. Dissanayaka Waruna Lakmal, Dr Chang Jeffrey Wen Wei, Professor Cheung Gary Shun Pan
Project Title: Synergistic effects of endothelial progenitor cells and apical papilla stem cells on dental pulp regeneration
Grant Type: General Research Fund (GRF)
Funding Year: 2010
Amount: HKD493000
Principal Investigator: Dr Zhang, Chengfei
Co-investigator(s): Professor Cheung Gary Shun Pan, Professor Jin Lijian, Professor Wang Cun-Yu

Invited Lectures and Keynote Speeches
01 May 2018: The precise control of root canal preparation and obturation, Xi'an & Shenyang China, 20 & 22 May 2018. .
01 May 2018: New theory and technology of modern root canal therapy, Xiamen, China, 5-6 May 2018. .
01 April 2018: The precise control of root canal preparation, Qingdao, China, 1 April 2018. A lecture on root canal therapy.
01 April 2018: The precise control of root canal preparation, Hangzhou, China, 7 April 2018. A lecture on root canal therapy.
01 March 2018: New theory and technology of modern root canal therapy, Shenzhen, China, 10-11 March 2018. .
01 December 2017: The role of pre-vascularization in pulp regeneration, 7 - 9 December. 2017 IADR Chinese Division Annual Meeting, Annual Conference of Fujian Stomatological Association, and Geriatric Dentistry Professional Board of Chinese Stomatological Association Annual Meeting.
01 November 2017: The precise control of root canal preparation, Nanning, China, 18 November 2017. A lecture on root canal therapy.
01 November 2017: Pulp regeneration and vital pulp therapy, and microscopic endodontic treatment . 29th Malaysian Endodontic Society Annual Scientific Conference and Annual General Meeting, Kuala Lumpur, Malaysia, 25 - 26 November, 2017.
01 November 2017: The precise control of root canal preparation, Jinan, China, 4 November 2017. A lecture on root canal therapy.
01 October 2017: The precise control of root canal preparation, Chengdu, China, 28 October 2017. A lecture on root canal therapy.
01 September 2017: Diagnosis and management of vertical root fractures, 12 September 2017. Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China.
01 September 2017: Clinical applications of regenerative endodontics, 14 September 2017, Faculty of Dentistry, The Univeristy of Hong Kong, Hong Kong. .
01 September 2017: Role of Interleukin-17 in bone modelling. Invited speech. 2017 China International Orthodontic Conference and the 16th Annual Meeting of Chinese Orthodontic Society, Sept 17-21, 2017, Shanghai, China.
01 August 2017: The precise control of root canal preparation, Shenzhen & Guangzhou, China, 21-22 August 2017. A lecture on root canal therapy.
01 August 2017: Several questions worthy to be discussed of root canal therapy, 6 August 2017. Microscopic root canal therapy and new progress of nickel-titanim instrument conference, Zhengzhou Stomatologic Hospital, Zhengzhou, China.
01 July 2017: Multidisciplinary cross-cutting oral aesthetics, 15-16 July 2017 Shenzhen Longgang E.N.T. Hospital, Shenzhen, China. Endodontic Continuing Training Course.
01 July 2017: Standardization construction in clinical teaching process of stomatology, 28-29 July 2017. Nanjing Medical University, Nanjing, China.
01 June 2017: Focusing on Endodontic Microsurgery - Leica Microsystems Summit. The 22nd China International Dental Exhibition & Scientific Conferene, Beijing, China, 10 June.
01 May 2017: The Clinical Techniques in Endodontics. Jinan Stomatological Hospital, 5-6 May.
01 April 2017: 3D Micro root canal therapy. Stomatological Hospital of Nantong, China, 8-9 April.
01 April 2017: Current status and advances on Modern Root Canal Therapy. Foshan Stomatological Hospital, Guangdong, China, 15 April.
01 January 2017: The Joint Scientific Symposium between the Dental Hospital Center for Global Oral Health at the Osaka University and Faculty of Dentistry HKU. January 12, 2017. Topic: The role of vasculature engineering in dental pulp regeneration.. .
01 January 2017: The role of vasculature engineering in dental pulp regeneration. Joint Scientific Symposium Current and Future Challenges in Dentistry, January 12, 2017.
01 December 2016: Endodontic Therapy. Ai Kang Jian Dental Hospital, Shengzhen, China, December.
01 December 2016: Dual impact of lipoteichoic acids from Enterococci faecalis on osteoclastogenesis. 16th Australasian BioCeramic Symposium, Queensland University of Technology, Brisbane, Australia, 6 December 2016.
01 November 2016: Theory and Practice of Problem-based Learning . Admissions and Academic Liaison Section, The Registry, The University of Hong Kong, 23 November.
01 November 2016: Regenerative Endodontics and Vital Pulp Therapy in Kolkata, India between 11-13 November 2016 . 31st IACDE & 24th IES National Conference.
01 October 2016: Microscope Root Canal Therapy. Nanjing Medical University, Nanjing, China, October.
01 September 2016: From Crack to Fracture in the Endodontic Continuing Training Course. Beijing University, Beijing, China, September.
01 July 2016: Endodontic Microsurgery Therapy. Tianjin Oral Medicine Dental Association, Tianjin, China, July.
01 June 2016: Topic: Derivation of endothelial and vascular smooth muscle cells from SHED for pulp regeneration.. 2016 94th General Session & Exhibition of the IADR in conjunction with the 3rd Meeting of the IADR Asia Pacific Region and the 35th Annual Meeting of the IADR Korean Division in Seoul, Republic of Korea. Symposium on “Clinical Translational Research on Dental Pulp Regeneration”..
01 June 2016: Topic: The role of scaffolding and prevascularization in pulp regeneration.. International Association for Dental Research (IADR) Pulp Biology Regeneration Group (PBRG) Symposium 2016, 26th-28th June 2016, Nagoya, Japan.
01 March 2016: Modern technique of root canal therapy, 11 March, 2016, Shenyang, China. .
01 January 2015: A 4 hours lecture in Putonghua on pulp regeneration, Beijing, China 23 January. .
01 December 2014: A keynote speech on pulp regeneration, West China School of Dentistry, Sichuan University, China, 4-6 December. .
01 December 2014: A keynote speech on pulp regeneration, Guangxi Stomatological Association, Guangxi, China,10-12 December. .
01 October 2014: Prevention and dealing with pain after endodontic treatment, 17 October. .
01 September 2014: A Keynote speech on Advances in Endodontics, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China, 23 September. .
16 July 2014: Problem-based Learning (PBL) at the HKU Faculty of Dentistry. Training program for a group of teachers from China Pharmaceutical University, 16 July.
10 June 2014: Keynote speech on latest developments in endodontics. Peking University, Beijing, China, 10-12 June.
30 May 2014: A keynote speech in endodontics. Endodontics Forum, 30 May.
29 November 2013: A keynote speech on: Advances in endodontics. Zhengzhou University, China, 29 November .
09 June 2013: Keynote speech on Dental pulp regeneration. School and Hospital of Stomatology, Peking University, China, June.
11 April 2013: Clinical procedures and case selection for pulp regeneration. 104th Annual Convention & Scientific Sessions, Philippine Dental Association, The Philippines, April.
12 December 2012: The new theory and technology of modern root canal therapy. Beijing Stomotological Hospital, Capital Medical University, China, Dec.
12 November 2012: International symposium. 50th Anniversary celebration of Dental School, School & Hospital of Stomatology, Wuhan University, China, November.
21 September 2012: Regenerative Endodontics: Where are we?. Continuing Education, Stomatological Department of Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China, September.
01 August 2012: Regenerative Endodontics: Biology and Clinical Application, Society of Endodontists Singapore, Singapore. .
01 June 2012: Endodontic Problems Management, Chinese International Dental Exhibition and Scientific Conference, Beijing China. .
01 July 2011: Regenerative Endodontics: clinical application. HuaXi Stomatological School, University of West China.
01 June 2011: Endodontic problems: prevention and amnagement. China International Dental Exhibition and Scientific Conference.
01 December 2010: Management of lower incisors and premolars with two canals in one root. The 1st Global Congress of Chinese Dentists.
01 June 2010: Management of two canals in one root. Capital Medical University School of Stomatology June.
01 April 2010: Regenerative Endodontics. Peking University School of Stomatology May.
01 February 2010: Clinical management of problems in Endodontic treatment. Hong Kong Dental Association Feb..
01 October 2009: Clinical management of clinical failure cases. Fujian Stomatological Association Nov. .

HKU Committee Appointments
01 July 2015-30 June 2017: Academic Awards, Board of. An Associate Dean (Undergraduate Education/Teaching and Learning), appointed on rotational basis for two years at a time, from Faculty Cluster B (Arts, Business & Economics, Education and Social Sciences)
01 February 2011-31 January 2013: Discontinuation, Committee on. 1 member from each Faculty (Dentistry) from a panel of three in order of precedence for a period of 2 years, renewable up to a maximum of 4 consecutive years
01 June 2009-31 May 2013: Faculty of Dentistry, Board of the. The teachers who are members of the Faculty and who are full-time employees of the University