Professor LEUNG Tak YeungCurrent Position:
Professor & Department Chairman
Team head of Fetal Medicine Team
Office Phone:
(852) 3505 2806
Email:
tyleung@cuhk.edu.hk
Qualifications:
MBChB (CUHK), MD (CUHK), FHKAM(O&G), FHKCOG, FRCOG
Other Positions:
Junior Vice President of HKCOG, Honorary Treasurer of OGSHK
Professor Tak Yeung LEUNG is the Chairman of the Department of Obstetrics and Gynaecology of The Chinese University of Hong Kong, as well as the Director of the Maternal Fetal Medicine of the same unit. His special interest is in prenatal screening, diagnosis and therapy of fetal abnormalities, twin pregnancy, preterm delivery, fetal growth restriction, shoulder dystocia and external cephalic version. He participated in the research and clinical application of maternal circulating cell-free fetal DNA for non-invasive prenatal diagnosis. In addition, he and his unit have successfully launched in Hong Kong the first trimester Down screening, array comparative genomic hybirdisation for prenatal diagnosis, maternal carrier screening for Fragile X disease, and newborn expanded metabolic screening, fetoscopic laser therapy for twin-twin transfusion, and radiofrequency for fetal reduction.
Professor Leung has published more than 280 papers in international peer reviewed journals. His current H-index is 38. He is also invited into the editorial board of international journals such as British Journal of Obstetricis and Gynaecology, American Journal of Perinatology, Pediatric Research (Fetus & Pregnancy Section), and Journal of Maternal Fetal & Neonatal Medicine.
Professor Leung is the Senior Vice President of Hong Kong College of Obstetricians and Gynaecologists, and previously was the Vice President and Honorary Treasurer of Obstetrical and Gynaecolgical Society of Hong Kong. Besides, Prof Leung has strong international and Asian-Pacific connection with appointments in several international professional bodies including: FIGO’s Preterm Working Group, Expert Panel for the revision of the FIGO intrapartum fetal monitoring guidelines, Chairman of the Prenatal Maternal Screening Special Interest Group of International Society for Prenatal Diagnosis, Foundation Board member of Global Obstetric Network (GONet), Foundation Secretary of The Chinese Fetal Medicine Foundation. He also collaborates with Baylor College of Medicine in running Master and Certificate genetic courses in Asia
Research Interest:
prenatal genetic screening, diagnosis and therapy of fetal abnormalities, twin pregnancy, preterm delivery, fetal growth restriction, and external cephalic version
Summary of research output:
Total number of publications: 280
Total citation: 4338
H-index: 38
Selected Publications
1 Chromosomal abnormalities and neurological outcomes in fetal cerebral ventriculomegaly: a retrospective cohort analysis
Lok WY, Kong CW, Hui SYA, Shi MM, Choy KW, To WK, Leung TY
Hong Kong Med J. 2021 Dec;27(6):428-436
2 Effectiveness of a childbirth massage programme for labour pain relief in nulliparous pregnant women at term: a randomised controlled trial Lai CY, Wong MKW, Tong WH, Chu SY, Lau KY, Tan AML, Hui LL, Lao TTH, Leung TY
Hong Kong Med J. 2021 Dec;27(6):405-412
3 Single-molecule sequencing reveals a large population of long cell-free DNA molecules in maternal plasma
Yu SCY, Jiang P, Peng W, Cheng SH, Cheung YTT, Tse OYO, Shang H, Poon LC, Leung TY, Chan KCA, Chiu RWK, Lo YMD
Proc Natl Acad Sci U S A. 2021 Dec 14;118(50):e2114937118
4 Bronchopulmonary sequestration treated successfully with prenatal radiofrequency ablation of feeding artery
Tse WT, Poon LC, Wah YM, Hui ASY, Ting YH, Leung TY
Ultrasound Obstet Gynecol. 2021 Aug;58(2):325-327
5 R4 RGS proteins suppress engraftment of human hematopoietic stem/progenitor cells by modulating SDF-1/CXCR4 signaling
Chan KYY, Zhang C, Wong YTS, Zhang XB, Wang CC, Ng WH, Fok SP, Tang PMK, Kang W, Feng B, Poon ENY, Lee KY, Lee CK, Chen C, Leung TY, Ng MHL, To KF, Wang H, Lam HS, Ng PC, Yuen PMP, Li K, Leung AWK, Li CK, Leung KT
Blood Adv. 2021 Nov 9;5(21):4380-4392
6 Umbilical cord prolapse: revisiting its definition and management
Wong L, Kwan AHW, Lau SL, Sin WTA, Leung TY
Am J Obstet Gynecol. 2021 Oct;225(4):357-366
7 Trio-Based Low-Pass Genome Sequencing Reveals Characteristics and Significance of Rare Copy Number Variants in Prenatal Diagnosis
Chau MHK, Qian J, Chen Z, Li Y, Zheng Y, Tse WT, Kwok YK, Leung TY, Dong Z, Choy KW
Front Genet. 2021 Sep 20;12:742325
8 First Trimester Screening for Preeclampsia: An Asian Perspective
Moungmaithong S, Wang XQ, Tai AST, Feng QL, Sahota D, Leung TY, Poon LC
Maternal-Fetal Medicine. 2021 Apr; 3(2):116-12
9 Molecular mechanism and pathways of normal human parturition in different gestational tissues: a systematic review of transcriptome studies
Ding W, Chim SSC, Wang CC, Lau CSL, Leung TY
Front Oncol. 2021 Sep 10;12:730030
10 Outcome of radiofrequency ablation for selective fetal reduction before vs at or after 16 gestational weeks in complicated monochorionic pregnancy
Ting YH, Poon LCY, Tse WT, Chung MY, Wah YM, Hui ASY, Law KM, Chaemsaithong P, Leung TY
Ultrasound Obstet Gynecol. 2021 Aug;58(2):214-220
11 Impact of replacing or adding placental growth factor on Down syndrome screening: A prospective cohort study
Sin AWT, Poon LC, Chaemsaithong P, Wah IYM, Hui ASY, Ting YH, Law KM, Leung TY, Sahota DS
Prenat Diagn. 2021 Aug;41(9):1111-1117
12 Expanded carrier screening using next-generation sequencing of 123 Hong Kong Chinese families: a pilot study
Chan OYM, Leung TY, Cao Y, Shi MM, Kwan AHW, Chung JPW, Choy KW, Chong SC
Hong Kong Med J. 2021 Jun;27(1):177-183
13 Bronchopulmonary sequestration successfully treated with prenatal radiofrequency ablation of the feeding artery
Tse WT, Poon LC, Wah YM, Hui ASY, Ting YH, Leung TY
Ultrasound Obstet Gynecol. 2021 Aug;58(2):325-327
14 The Use of Somatex Shunt for Fetal Pleural Effusion: A Cohort of 8 Procedures
Chung MY, Leung WC, Tse WT, Ting YH, Law KM, Hui ASY, Wah YM, Lam HS, Poon LCY, Leung TY
Fetal Diagn Ther. 2021;48(6):440-447
15 Low-pass genome sequencing-based detection of absence of heterozygosity: validation in clinical cytogenetics
Dong Z, Chau MHK, Zhang Y, Yang Z, Shi M, Wah YM, Kwok YK, Leung TY, Morton C, Choy KW
Genet Med. 2021 Jul;23(7):1225-1233
16 Single-cell RNA sequencing identifies molecular targets associated with poor in vitro maturation performance of oocytes collected from ovarian stimulation
Lee AWT, Ng JKW, Liao J, Luk AC, Suen AHC, Chan TTH, Cheung MY, Chu HT, Tang NLS, Zhao MP, Lian Q, Chan WY, Chan DYL, Leung TY, Chow KL, Wang W, Wang LH, Chen NCH, Yang WJ, Huang JY, Li TC, Lee TL
Hum Reprod. 2021 Jun 18;36(7):1907-1921
17 Characteristics of Fetal Extrachromosomal Circular DNA in Maternal Plasma: Methylation Status and Clearance
Sin STK, Ji L, Deng J, Jiang P, Cheng SH, Heung MMS, Lau CSL, Leung TY, Chan KCA, Chiu RWK, Lo YMD
Clin Chem. 2021 Apr 29;67(5):788-796
18 Clinical Implementation of Expanded Carrier Screening in Pregnant Women at Early Gestational Weeks: A Chinese Cohort Study
Shi M, Liauw AL, Tong S, Zheng Y, Leung TY, Chong SC, Cao Y, Lau TK, Choy KW, Chung JPW
Genes (Basel). 2021 Mar 29;12(4):496
19 Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology
Gai W, Zhou Z, Agbor-Enoh S, Fan X, Lian S, Jiang P, Cheng SH, Wong J, Chan SL, Jang MK, Yang Y, Liang RH, Chan WK, Ma ES, Leung TY, Chiu RW, Valantine H, Chan KA, Lo YD
Elife. 2021 Mar 23;10:e64356
20 Genome-wide detection of cytosine methylation by single molecule real-time sequencing
Tse OYO, Jiang P, Cheng SH, Peng W, Shang H, Wong J, Chan SL, Poon LCY, Leung TY, Chan KCA, Chiu RWK, Lo YMD
Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2019768118
21 Performance of Cell-Free DNA Screening for Fetal Common Aneuploidies and Sex Chromosomal Abnormalities: A Prospective Study from a Less Developed Autonomous Region in Mainland China
Lai Y, Zhu X, He S, Dong Z, Tang Y, Xu F, Chen Y, Meng L, Tao Y, Yi S, Su J, Huang H, Luo J, Leung TY, Wei H
Genes 2021 Mar;12(4):12040478
22 Clinical utility of expanded non-invasive prenatal screening and chromosomal microarray analysis in high-risk pregnancy
Zhu X, Chen M, Wang H, Guo Y, Chau MHK, Yan H, Cao Y, Kwok YKY, Chen J, Hui ASY, Zhang R, Meng Z, Zhu Y, Leung TY, Xiong L, Kong X, Choy KW
Ultrasound Obstet Gynecol. 2021 Mar;57(3):459-465
23 Deciphering the complexity of simple chromosomal insertions by genome sequencing
Dong Z, Chau MHK, Zhang Y, Dai P, Zhu X, Leung TY, Kong X, Kwok YK, Stankiewicz P, Cheung SW, Choy KW
Hum Genet. 2021 Feb;140(2):361-380
24 The role of chromosomal microarray analysis among fetuses with normal karyotype and single system anomaly or nonspecific sonographic findings
Hui ASY, Chau MHK, Chan YM, Cao Y, Kwan AHW, Zhu X, Kwok YKY, Chen Z, Lao TTH, Choy KW, Leung TY
Acta Obstet Gynecol Scand. 2021 Feb;100(2):235-243
25 Noninvasive prenatal sequencing for multiple Mendelian monogenic disorders among fetuses with skeletal dysplasia or increased nuchal translucency
Yan H, Zhu X, Chen J, Cao Y, Kwok YKY, Chen Z, Leung TY, Chen M, Choy KW
Prenat Diagn. 2020 Oct;40(11):1459-1465
26 Clinical Significance of Non-Invasive Prenatal Screening for Trisomy 7: Cohort Study and Literature Review?
Zhu X, Lam DYM, Chau MHK, Xue S, Dai P, Zhao G, Cao Y, Cheung SWH, Kwok YKY, Choy KW, Kong X, Leung TY?
Genes (Basel). 2020 Dec 24;12(1):E11
27 Bradycardia-to-delivery interval and fetal outcomes in umbilical cord prolapse
Wong L,?Tse WT,?Lai CY,?Hui ASY,?Chaemsaithong P, Sahota DS,?Poon?LC,?Leung TY
Acta Obstet Gynecol Scand. 2021 Jan;100(1):170-177
28 Whole-transcriptome analysis of maternal blood for identification of RNA markers for predicting spontaneous preterm birth among preterm labour women: abridged secondary publication
Chim SSC, Chan TF, Leung TY?
Hong Kong Med J. 2020 Dec;26 Suppl 6(6):20-23
29 Feasibility, Reliability and Agreement of Transperineal Ultrasound Measurement: Result from a Longitudinal Cohort Study
Kwan AHW, Chaemsaithong P, Tse WT, Appiah K, Chong KC, Leung TY, Poon LC
Fetal Diagn Ther 2020 Oct;47(10):721–730
30 Low-pass genome sequencing: a validated method in clinical cytogenetics???
Chau MHK, Wang H, Lai Y, Zhang Y, Xu F, Tang Y, Wang Y, Chen Z, Leung TY, Chung JPW, Kwok YK, Chong SC, Choy KW, Zhu Y, Xiong L, Wei W, Dong Z?????????????
Hum Genet. 2020 Nov;139(11):1403-1415
31 Monochorionic twins with selective fetal growth restriction: insight from placental whole transcriptome analysis
LI W, Chung CYL, Wang CC, Chan TF, Leung MBW, Chan OK, Wu L, APPIAH K, Chaemsaithong P, Cheng YKY, Poon LCY, Leung TY
Am J Obstet Gynecol. 2020 Nov;223(5):749.e1-749.e16
32 Shear-wave sonoelastographic assessment of cervix in pregnancy
Duan H, Chaemsaithong P, Ju X, Ho SYS, Sun Q, Tai Y, Leung TY, Poon LC
Acta Obstet Gynecol Scand. 2020 Nov;99(11):1458-1468???
33 Detection and characterization of jagged ends of double-stranded DNA in plasma
Jiang P, Xie T, Ding SC, Zhou Z, Cheng SH, Chan RWY, Lee WS, Peng W, Wong J, Wong VWS, Chan HL, Chan SL, Poon LC, Leung TY, Chan AKC, Chiu RWK, Lo DYM
Genome Res. 2020 Aug;30(8):1144-1153???????????????????????????????
34 First-trimester pre-eclampsia biomarker profiles in Asian population: a multicenter cohort study
Chaemsaithong P, Sahota D, Pooh RK, Zheng M, Ma R, Chaiyasit N, Koide K, Shaw SW, Seshadri S, Choolani M, Panchalee T, Yapan P, Sim WS, Sekizawa A, Hu Y, Shiozaki A, Saito S, Leung TY, Poon LC??
Ultrasound Obstet Gynecol. 2020 Aug;56(2):206-214
35 ISUOG Interim Guidance on coronavirus disease 2019 (COVID-19) during pregnancy and puerperium: information for healthcare professionals - an update (INTERIM GUIDANCE)
Poon LC, Yang H, Dumont S, Lee JCS, Copel JA, Danneels L, Wright A, Costa FD, Leung TY, Zhang Y, Chen D, Prefumo F
Ultrasound Obstet Gynecol. 2020 Jun;55(6):848-862
36 The utility of genome-wide cell-free DNA screening in the prenatal diagnosis of Pallister-Killian syndrome
Chau MHK, Lam YKD, Zhu X, Kwok YKY, Ting YH, Chan WP, Shi M, Cheung WH, Lau TK, Ville Y, Leung TY, Choy KW
Prenat Diagn. 2020 Jul;40(8):1005-1012
37 Perioperative prophylactic internal iliac artery balloon occlusion in the prevention of postpartum hemorrhage in placenta previa: a randomized controlled trial
Yu SCH, Cheng YKY, Tse WT, Sahota DS, Chung MY, Wong SSM, Chan OK, Leung TY
Am J Obstet Gynecol. 2020 Jul;223(1):117.e1-117.e13
38 ISUOG Interim Guidance on 2019 novel coronavirus infection during pregnancy and puerperium: information for healthcare professionals
Poon LC, Yang H, Lee JCS, Copel JA, Leung TY, Zhang Y, Chen D, Prefumo F
Ultrasound Obstet Gynecol. 2020 May;55(5):700-708
39 Plasma DNA end motif profiling as a fragmentomic marker in cancer, pregnancy and Transplantation
Jiang P, Sun K, Peng W, Cheng SH, Ni M, Yeung PC, Heung MMS, Xie T, Shang H, Zhou Z, Chan RWY, Wong J, Wong VWS, Poon LC, Leung TY, Lam WKJ, Chan JYK, Chan HLY, Chan KCA, Chiu RWK, Lo YMD
Cancer Discov. 2020 May;10(5):664-673
40 Placental microRNA dataset of monochorionic twin pregnancies with and without selective fetal growth restriction
Meng M, Cheng YKK, Wu L, Chaemsaithong P, Leung MBW, Chim SSC, Sahota DS, Li W, Poon LCY, Wang CC, Leung TY
Data in Breif Volume 30, June 2020, 105403
41 Low-pass genome sequencing versus chromosomal microarray analysis: implementation in prenatal diagnosis
Wang H, Dong Z, Zhang R, Chau MHK, Yang Z, Tsang K, Wong HK, Gui B, Meng Z, Xiao K, Zhu X, Wang Y, Chen S, Leung TY, Cheung SW, Kwok YK, Morton CC, Zhu Y, Choy KW
Genet Med, 2020 Mar;22(3):500-510
42 Identification and characterization of extrachromosomal circular DNA in maternal plasma
Sin STK, Jiang P, Deng J, Ji L, Cheng SH, Dutta A, Leung TY, Chan KCA, Chiu RWK, Lo YMD
Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1658-1665
43 Whole genome miRNA profiling revealed miR-199a as potential placental pathogenesis of selective fetal growth restriction in monochorionic twin pregnancies
Meng M, Cheng YKK, Wu L, Chaemsaithong P, Leung MBW, Chim SSC, Sahota DS, Li W, Poon LC, Wang CC, Leung TY
Placenta Volume 92, March 2020, Pages 44-53
44 The predictive value of cervical shear wave elastography in the outcome of labor induction
Lu J, Cheng YKY, Ho SYS, Sahota DS, Hui LL, Poon LC, Leung TY
Acta Obstet Gynecol Scand. 2020 Jan;99(1):59-68
45 Characteristics and mode of inheritance of pathogenic copy number variants in prenatal diagnosis
Chau MHK, Cao Y, Kwok YKY, Chan S, Chan YM, Wang H, Yang Z, Wong HK, Leung TY, Choy KW
American Journal of Obstetrics and Gynecology 2019;221(5):493e1-e11.
46 Genome Sequencing Explores Complexity of Chromosomal Abnormalities in Recurrent Miscarriage
Dong Z, Yan J, Xu F, Yuan J, Jiang H, Wang H, Chen H, Zhang L, Ye L, Xu J, Shi Y, Yang Z, Cao Y, Chen L, Li Q, Zhao X, Li J, Chen A, Zhang W, Wong HG, Qin Y, Zhao H, Chen Y, Li P, Ma T, Wang WJ, Kwok YK, Jiang Y, Pursley AN, Chung JPW, Hong Yan, Kristiansen K, Yang H, Pi?a-Aguilar RE, Leung TY, Cheung SW, Morton CC, Choy KW, Chen ZJ
Am J Hum Genet. 2019 Dec 5;105(6):1102-1111
47 Prenatal diagnosis of pathogenic genomic imbalance in fetuses with increased nuchal translucency but normal karyotyping using chromosomal microarray
Leung TY, Au Yeung KC, Leung WC, Leung KY, Lo TK, To WWK, Lau WL, Chan LW, Sahota DS, Choy RKW
Hong Kong Med J. 2019 Aug;25 Suppl 5(4):30-32
48 Hypoechoic Liver in Fetuses with Trisomy 21 (CASE REPORT)
Omar PM, Lim WT, Ting YH, Lao TT, Law KM, Cheung AHK, Ng JKM, Leung TY
J Matern Fetal Neonatal Med. 2019 Oct;32(19):3315-3317
49 Prenatal visualization of paraumbilical veins in fetus with intra-abdominal umbilical vein stricture and intrauterine growth restriction
Chan YM, Law KM, Poon LC, Leung TY
Ultrasound Obstet Gynecol. 2019 Nov;54(5):697-698
50 Topologic analysis of plasma mitochondrial DNA reveals the coexistence of both linear and circular molecules.
Ma ML, Zhang H, Jiang P, Sin STK, Lam WKJ, Cheng SH, Lee WS, Gai W, Tse OYO, Peng W, Wong J, Raghupathy R, Wong RSM, Sahota DS, Leung TY, Chan KCA, Chiu RWK, Lo YMD.
Clin? Chem 2019 Sep;65(9):1161-1170
51 Inter-manufacturer comparison of automated immunoassays for the measurement of soluble FMS-like tyrosine kinase-1 and placental growth factor
Cheng YKY, Poon LC, Shennan A, Leung TY, Sahota DS
Pregnancy Hypertens. 2019 Jul;17:165-171
52 Prenatal Diagnosis of Fetuses with Increased Nuchal Translucency by Genome Sequencing Analysis
Choy KW, Wang H, Shi M, Chen J, Yang Z, Zhang R, Yan H, Wang Y, Chen S, Chau MHK, Cao Y, Chan OYM, Kwok YK, Zhu Y, Chen M, Leung TY, Dong Z
Front Genet. 2019 Aug; volume 10:761 (14 pages)
53 Transvaginal three-dimensional assessment of Sylvian fissures at 18-30 weeks’ gestation
Poon LC, Sahota DS, Chaemsaithong P, Nakamura T, Machida M, Naruse K, Wah IYM, Leung TY, Pooh RK
Ultrasound Obstet Gynecol. 2019 Aug;54(2):190-198
54 Parental consanguinity in Hong Kong
Siong KH, Yeung SKCA, Leung TY
Hong Kong Med J. 2019 Jun;25(3):192-200
55 Hypoechoic Liver in Fetuses with Trisomy 21
Omar PM, Lim WT, Ting YH, Lao TT, Law KM, Cheung AHK, Ng JKM, Leung TY
J Matern Fetal Neonatal Med. 2019 Oct;32(19):3315-3317
56 Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin
Sun K, Jiang P, Cheng SH, Cheng THT, Wong J, Wong VWS, Ng SSM, Ma BBY, Leung TY, Chan SL, Mok TSK, Lai PBS, Chan HLY, Sun H, Chan KCA, Chiu RWK, Lo YMD
Genome Res. 2019 Mar;29(3):418-427
57 Prevalence of chromosomal abnormalities and 22q11.2 deletion in conotruncal and non-conotruncal antenatally diagnosed congenital heart diseases in a Chinese population
Kong CW, Cheng YKY, To WW, Leung TY
Hong Kong Med J. 2019 Feb;25(1):6-12
58 Screening and prevention of pre-eclampsia: a review
Chaemsaithong P , Appiah EK , Sahota DS , Leung TY, Poon LC
Hong Kong J Gynaecol Obstet Midwifery 2019;19(1):56-72
59 Factors that affect ultrasound-determined labor progress in women undergoing induction of labor
Chaemsaithong P, Kwan AHW, Tse WT, Lim WT, Chan WWY, Chong KC, Leung TY, Poon LC
Am J Obstet Gynecol. 2019 Jun;220(6):592.e1-592.e15
60 Enrichment of fetal and maternal long cell-free DNA fragments from maternal plasma following DNA repair
Vong JSL, Jiang P, Cheng SH, Lee WS, Tsang JCH, Leung TY, Chan KCA, Chiu RWK, Lo YMD
Prenat Diagn. 2019 Jan;39(2):88-99
61 Comparative analysis of single-cell parallel sequencing approaches in oocyte application
Qian Y, Liao J, Suen AHC, Lee AWT, Chung HS, Tang NLS, Chow KL, Cao Q, Yip YL, Leung TY, Chan WY, Chan DYL, Li TC, Lee TL
Int J Biochem Cell Biol. 2019 Feb;107:1-5
62 Pre-induction transperineal ultrasound assessment for the prediction of labor outcome
Chan WWY, Chaemsaithong P, Lim WT, Tse AWT, Kwan AHW, Leung TY, Sahota D, Poon LC
Fetal Diagn Ther. 2019 Apr;45(4):256-267
63 Body mass index at 11–13 weeks’ gestation and pregnancy complications in a Southern Chinese population: a retrospective cohort study
Chaemsaithong P, Leung TY, Sahota D, Cheng YKY, Leung WC, Lo TK, Poon LCY
J Matern Fetal Neonatal Med. 2019 Jun;32(12):2056-2068
64 Objective assessment of the fetal facial profile at second and third trimester of pregnancy
Lu J, Sahota DS, Poon LC, Ting YH, Cheng YKY, Wang Y, Leung TY
Prenat Diagn. 2019 Jan;39(2):107-115
65 Maternal height and risk of hypertensive disorders in pregnancy
Lao TT, Hui ASY, Sahota DS, Leung TY
J Matern Fetal Neonatal Med. 2019 May;32(9):1420-1425
66 Transverse technique: complementary approach to measurement of first-trimester uterine artery Doppler
Drouin O, Johnson J, Metcalfe A, Huber J, Schwarzenberger J,? Winters E, Stavness L, Chaemsaithong P, Tse AWT, Lu J, Lim WT, Leung TY, Bujold E, Sahota D, Poon LC
Ultrasound Obstet Gynecol. 2018 Nov;52(5):639-647
67 Prediction of labor outcome using serial transperineal ultrasound in the first stage of labor
Chor CM, Poon LC, Leung TY
J Matern Fetal Neonatal Med. 2019 Jan;32(1):31-37
68 Pitfalls in assessing chorioamnionicity: novel observations and literature review
Lu J, Cheng YKY, Ting YH, Law KM, Leung TY
Am J Obstet Gynecol. 2018 Sep;219(3):242-254
69 Molecular and clinical characterization of citrin de?ciency in a cohort of Chinese patients in Hong Kong
Chong SC, Lo P, Chow CW, Yuen L, Chu WCW, Leung TY, Hui J, Scaglia F
Mol Genet Metab Rep. 2018 Sep 1;17:3-8
70 Identification of balanced chromosomal rearrangements previously unknown among participants in the 1000 Genomes Project: implications for interpretation of structural variation in genomes and the future of clinical cytogenetics
Dong Z, Wang H, Chen H, Jiang H, Yuan J, Yang Z, Wang WJ, Xu F, Guo X, Cao Y, Zhu Z, Geng C, Cheung CWC, Kwok YKY, Yang H, Leung TY, Morton CC, Cheung SW, Choy KW
Genet Med. 2018 Jul;20(7):697-707
71 Soluble fms-like tyrosine kinase-1 and placental growth factor in Chinese pregnant women during second and third trimesters
Cheng YKY, Law LW, Leung TY , Chan OK , Sahota DS
Hong Kong Med J. 2018 Jun;24 Suppl 3(3):45-47
72 Target-enriched massively parallel sequencing for genetic diagnosis of hereditary hearing loss in patients with normal array CGH result
Choy KW, Cao Y, Lam STS, Lo FM, Morton CC, Leung TY
Hong Kong Med J. 2018 Jun;24 Suppl 3(3):11-14
73 Uterine artery pulsatility index in the first trimester: assessment of intersonographer and intersampling site measurement differences
Chaemsaithong P, Ting YH, Cheng KYY, Poon CYL, Leung TY, Sahota DS
J Matern Fetal Neonatal Med. 2018 Sep;31(17):2276-2283
74 Prospective assessment of INTERGROWTH-21st and World Health Organization estimated fetal weight reference curves
Cheng YKY, Lu J, Leung TY, Chan YM, Sahota DS
Ultrasound Obstet Gynecol. 2018 Jun;51(6):792-798
75 Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing
Sun K, Jiang P, Wong AIC, Cheng YKY, Cheng SH, Zhang H, Chan KCA, Leung TY, Chiu RWK, Lo YMD
Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5106-E5114
76 Soluble fms-like tyrosine kinase-1, placental growth factor and their ratio as a predictor for pre-eclampsia in East Asians
Cheng YKY, Law LW, Leung TY, Chan OK, Sahota DS
Pregnancy Hypertens. 2018 Jan;11:61-65
77 Noninvasive reconstruction of placental methylome from maternal plasma DNA: Potential for prenatal testing and monitoring
Sun K, Lun FMF, Leung TY, Chiu RWK, Lo YMD, Sun H
Prenat Diagn. 2018 Feb;38(3):196-203
78 First trimester screening for pre-eclampsia in Chinese pregnancies: case–control study
Cheng YKY, Leung TY, Law LW, Ting YH, Law KM, Sahota DS
BJOG. 2018 Mar;125(4):442-449
79 Women’s preference for non-invasive prenatal DNA testing versus chromosomal microarray after screening for Down syndrome: a prospective study
Cheng YKY, Leung WC, Leung TY, Choy KW, Chiu RWK, Lo TK, Kwok KY, Sahota DS
BJOG. 2018 Mar;125(4):451-459
80 Uses of FloSeal? in obstetric hemorrhage: Case series and literature review
Chung JP, Leung TY
Taiwan J Obstet Gynecol. 2017 Dec;56(6):827-830
81 Establishing Prenatal Surgery for Myelomeningocele in Asia: The Singapore Consensus
Wataganara T, Seshadri S, Leung TY, Matter C, Ngerncham M, Triyasunant N, Mali PV, Biswas A, Nawapun K, Phithakwatchara N, Flake AW, Johnson MP, Biswas A, Choolani M.
Fetal Diagn Ther. 2017 Apr;41(3):161-178
82 Single-Stranded DNA Library Preparation Preferentially Enriches Short Maternal DNA in Maternal Plasma
Vong JSL, Tsang JCH, Jiang P, Lee WS, Leung TY, Chan KCA, Chiu RWK, Lo YMD
Clin Chem. 2017 May;63(5):1031-1037
83 Preface: Issue 39
Leung TY
Best Pract Res Clin Obstet Gynaecol. 2017 Feb;39:1-2
84 First Report of a Novel Deletion Due to εγδβ-Thalassemia in a Chinese Family
Hui ASY, Au PKC, Ting YH, Kan ASY, Cheng YKY, Leung AWK, Chan KYK, Li CK, Tang MHY, Leung TY
Hemoglobin. 2017 Sep;41(3):175-179
85 Expanded newborn metabolic screening programme in Hong Kong: a three-year journey
Chong SC, Law LK, Hui J, Lai CY, Leung TY, Yuen YP
Hong Kong Med J. 2017 Oct;23(5):489-96
86 Triplet pregnancy with fetal reduction: experience in Hong Kong
Tse WT, Law LW, Sahota DS, Leung TY, Cheng YK
Hong Kong Med J. 2017 Aug;23(4):326-32
87 Ultrasound-Guided Percutaneous Embolisation of Placental Chorioangioma Using Cyanoacrylate
Cheng YK, Yu SC, So PL, Leung TY
Fetal Diagn Ther. Feb 2017;41(1):76-79
88 Antenatal diagnosis and management of foetal intestinal volvulus
Yip KW, Cheng YKY, Leung TY
Med J Malaysia. 2017 Apr;72(2):126-127
89 Prenatal Diagnosis of a Retroesophageal Left Brachiocephalic Vein: Two Case Reports
Cheng YKY, Law KM, Chak PK, To KF, Chan YM, Leung TY
J Ultrasound Med. 2017 May;36(5):1065-1069
90 Systematic Selection of Reference Genes for the Normalization of Circulating RNA Transcripts in Pregnant Women Based on RNA-Seq Data
Chim SSC, Wong KKW, Chung CYL, Lam SKW, Kwok JSL, Lai CY, Cheng YKY, Hui ASY, Meng M, Chan OK, Tsui SKW, Lee KY, Chan TF, Leung TY
Int J Mol Sci. 2017 Aug 4;18(8): E1709.
91 Maternal rubella immunity status and pre-eclampsia
Lao TT, Sahota DS, Law LW, Leung TY
Am J Reprod Immunol. 2017 Jul;78(1):e12677
92 Procedure-Related Fetal Loss following Chorionic Villus Sampling after First-Trimester Aneuploidy Screening
Wah YM, Leung TY, Cheng YKY, Sahota DS
Fetal Diagn Ther. Apr 2017;41(3):184-190
93 Identification of fragile X pre-mutation carriers in the Chinese obstetric population using a robust FMR1 polymerase chain reaction assay: implications for screening and prenatal diagnosis
Cheng Y KY , Lin CSW, Kwok YKY, Chan YM , Lau TK , Leung TY , Choy KW
Hong Kong Med J. 2017 Apr;23(2):110-6
94 The pattern of cervical smear abnormalities in marginalised women in Hong Kong
Ting YH, Tse HY, Lam WC, Chan KS, Leung TY
Hong Kong Med J. 2017 Feb;23(1):28-34
95 Combined Count- and Size-Based Analysis of Maternal Plasma DNA for Noninvasive Prenatal Detection of Fetal Subchromosomal Aberrations Facilitates Elucidation of the Fetal and/or Maternal Origin of the Aberrations
Yu SC, Jiang P, Allen Chan KC, Faas BH, Choy KW, Leung WC, Leung TY, Dennis Lo YM, Chiu RW
Clin Chem. 2017 Feb;63(2):495-502
96 Gestational Age Assessment by Methylation and Size Profiling of Maternal Plasma DNA: A Feasibility Study
Jiang P, Tong YK, Sun K, Cheng SH, Leung TY, Allen Chan KC, Chiu RW, Ming Dennis Lo Y
Clin Chem. 2017 Feb;63(2):606-608
97 Universal Haplotype-Based Noninvasive Prenatal Testing for Single Gene Diseases
Hui WW, Jiang P, Tong YK, Lee WS, Cheng YK, New MI, Kadir RA, Chan KC, Leung TY, Lo YM, Chiu RW
Clin Chem Feb 2017 ;63(2):513-524
98 Second Generation Noninvasive Fetal Genome Analysis Reveals De Novo Mutations, Single-Base Parental Inheritance, and Preferred DNA Ends
Chan KC, Jiang P, Sun K, Cheng YK, Tong YK, Cheng SH, Wong AI, Hudecova I, Leung TY, Chiu RW, Lo YM
Proc Natl Acad Sci U S A Dec 2016;113(50):E8159-E8168
99 Cell-Free Dna In Maternal Plasma And Serum: A Comparison Of Quantity, Quality And Tissue Origin Using Genomic And Epigenomic Approaches
Wong FC, Sun K, Jiang P, Cheng YK, Chan KC, Leung TY, Chiu RW, Lo YM
Clin Biochem 2016 Dec;49(18):1379-1386
100 Predictive factors for the success of McRoberts' manoeuvre and suprapubic pressure in relieving shoulder dystocia: a cross-sectional study
Lok ZLZ, Cheng YKY, Leung TY
BMC Pregnancy Childbirth. 2016 Oct 29;16(1):334
101 Prenatal detection of 10q22q23 duplications: dilemmas in phenotype prediction
Kong GWS, Cao Y, Huang J, Cheng KY, Pursley AN, Rosenfeld JA, Edwards J G, Chan YM, Cheung SW, Leung TY, Choy KW
Prenat Diagn. 2016 Dec;36(13):1211-1216
102 Debates on Fetal Fraction Measurement and DNA-based Noninvasive Prenatal Screening: Time for Standardisation.
Wataganara T, Bui TH, Choy KW, Leung TY
BJOG Sep 2016;123(S3): 31 – 35
103 Impact of Replacing Chinese Ethnicity-specific Fetal Biometry Charts with the INTERGROWTH-21St Standard.
Cheng YKY, Leung TY, Lao TTH, Chan OYM, Sahota DS
BJOG Sep 2016;123(S3): 48 – 56
104 Pseudoamniotic Band Syndrome after In Utero Intervention for Twin-to-Twin Transfusion Syndrome: Case Reports and Literature Review.
Ting YH, Lao TTH, Law KM, Cheng YKY, Lau TK, Leung TY
Fetal Diagn Ther Jul 2016;40(1): 67 – 72
105 Validation of a Robust PCR-Based Assay for Quantifying Fragile X CGG Repeats.
Kwok YKY, Wong CKM, Lo FM, Kong GWS, Moore JK, Wu S, Lam STS, Schermer M, Leung TY, Choy KW
Clin Chim Acta Mar 2016;456(2016): 137 – 143
106 Accurate Description of DNA-based Noninvasive Prenatal Screening.
Cheung SW, Petal A,?Leung TY
N Engl J Med 2015;372(17): 1675 - 1677
107 Evaluation of an In-house Real-time Polymerase Chain Reaction Method to Identify Group B Streptococcus Colonization in Pregnancy.
Yeung SW, Cheung PT, Chau SL, Ip M, Lao TTH,?Leung TY, Tam WH
J Obstet Gynaecol Res 2015;41(9): 1357 - 1362
108 Noninvasive Prenatal Testing by Nanopore Sequencing of Maternal Plasma DNA: Feasibility Assessment.
Cheng SH, Jiang PY, Sun K, Cheng YKY, Chan AKC,?Leung TY, Chiu RWK, Lo DYM
Clin Chem 2015;61(10): 1305 - 1306
109 Plasma DNA Tissue Mapping by Genome-Wide Methylation Sequencing for Noninvasive Prenatal, Cancer, and Transplantation Assessments.
Sun K, Jiang PY, Chan AKC, Wong J, Cheng YKY, Liang RHS, Chan WK, Ma ESK, Chan SL, Cheng SH, Chan RWY, Tong YK, Ng SSM, Wong RSM, Hui DSC, Leung TN,?Leung TY, Lai PBS, Chiu RWK, Lo DYM
Proc Natl Acad Sci USA 2015;112(40): e5503 - e5512
110 Prevalence of Recurrent Pathogenic Microdeletions and Microduplications in Over 9500 Pregnancies.
Grati F, Gomes DM, Ferreira JCPB, Dupont C, Alesi V, Gouas L, Horelli-Kuitunen N, Choy KW, Garcia-Herrero S, Gonzalez de la Vega A, Piotrowski K, Genesio R, Queipo G, Malvestiti B, Herve B, Benzacken B, Novelli A, Vago P, Piippo K,?Leung TY, Maggi F, Quibel T, Tabet AC, Simoni G, Vialard F
Prenatal Diag 2015;35(8): 801 - 809
111 Randomized Trial of Anaesthetic Interventions in External Cephalic Version for Breech Presentation.
Khaw KS, Lee SWY, Ngan Kee WD, Law LW, Lau TK, Ng F,?Leung TY
Br J Anaesth 2015;114(6): 944 - 950
112 Rubella Seronegativity in Antenatal Screening - Is It Influenced by the Introduction of Universal Childhood Rubella Immunization?
Lao TTH, Sahota DS, Law LW,?Leung TY
Vaccine 2015;33(38): 4776 - 4781
113 Seasonality of Fetal Trisomy 21 - Have Ambient Air Pollutants Played A Role?
Chung MK, Lao TTH, Ting YH, Wong TW,?Leung TY
J Matern Fetal Neonatal Med 2015;28(5): 552 - 557
114 Women s Uptake of Non-Invasive DNA Testing Following a High-risk Screening Test for Trisomy 21 within a Publicly Funded Healthcare System Findings from a Retrospective Review.
Chan OYM, Leung WC, Chan WP,?Leung TY, Cheng YKY, Sahota DS
Prenatal Diag 2015;35(4): 342 - 347
115 A Study of the Immune Properties of Human Umbilical Cord Lining Epithelial Cells.
Cai YJ, Huang L,?Leung TY, Burd A
Cytotherapy 2014;16(5): 631 - 639
116 Advanced Maternal Age and Postpartum Hemorrhage - Risk Factor or Red Herring?
Lao TTH, Sahota DS, Cheng YKY, Law LW,?Leung TY
J Matern Fetal Neonatal Med 2014;27(3): 243 - 246
117 Age-specific Prevalence of Hepatitis B Virus Infection in Young Pregnant Women, Hong Kong Special Administrative Region of China.
Lao TTH, Sahota DS, Law LW, Cheng YKY,?Leung TY
Bull World Health Organ 2014;92(11): 782 - 789
118 BACs-on-beads A New Robust and Rapid Detection Method For Prenatal Diagnosis.
Choy KW, Chen Y, Sun XF, Kwok YKY,?Leung TY
Expert Rev Mol Diagn 2014;14(3): 273 - 280
119 Comparison of the Effect of Penicillins versus Erythromycin in Preventing Neonatal Group B Streptococcus Infection in Active Carriers Following Preterm Prelabor Rupture of Membranes.
Yeung SW, Sahota DS,?Leung TY
Taiwan J Obstet Gynecol 2014;53(2): 210 - 214
120 Diagnostic Accuracy of the Bacs-on-Beads ? Assay Versus Karyotyping for Prenatal Detection of Chromosomal Abnormalities: A Retrospective Consecutive Case Series.
Choy KW, Kwok YKY, Cheng YKY, Wong CKM, Wong HK, Leung KO , Suen AKW, Adler K, Wang CC, Lau TK, Schermer M, Lao TTH,?Leung TY
BJOG 2014;121(10): 1245 - 1252
121 Expression Profile of Cord Blood Neutrophils and Dysregulation of HSPA1A and OLR1 upon Challenge by Bacterial Peptidoglycan.
Fong ON, Chan KYY, Leung KT, Lam HS, Cheung HM,?Leung TY, Li KKH, Ng PC
J Leukoc Biol 2014;95(1): 169 - 178
122 Intra- and Inter-observer Reproducibility of Ultrasound Measurements of Pelvic Inlet Diameter in Pregnant Women.
Wah IYM, Chan OYM, Sahota DS, Hui ASY, Lau TK,?Leung TY
Open Journal of Obstetrics and Gynecology 2014;2014(4): 653 - 658
123 Is High Fetal Nuchal Translucency Associated with Submicroscopic Chromosomal Abnormalities on Array CGH?
Huang J, Poon LC, Akolekar R, Choy KW,?Leung TY, Nicolaides KH
Ultrasound Obst Gyn 2014;43(6): 620 - 624
124 Maternal ABO and Rhesus Blood Group Phenotypes And Hepatitis B Surface Antigen Carriage.
Lao TTH, Sahota DS, Chung MK, Cheung TKW, Cheng YKY,?Leung TY
J Viral Hepatitis 2014;21(11): 818 - 823
125 Maternal Plasma Fetal DNA Fractions in Pregnancies with Low and High Risks for Fetal Chromosomal Aneuploidies.
Hudecova I, Sahota DS, Heung MS, Jin YJ, Lee WS,?Leung TY, Lo DYM, Chiu RWK
PLos ONE 2014;9(2): e88484
126 Maternal Plasma RNA Sequencing for Genome-wide Transcriptomic Profiling and Identification of Pregnancy-associated Transcripts .
Tsui NBY, Jiang PY, Wong YF,?Leung TY, Chan AKC, Chiu RWK, Sun H, Lo DYM
Clin Chem 2014;60(7): 954 - 962
127 Nonremoval of an Abnormally Invasive Placenta at Cesarean Section with Postoperative Uterine Artery Embolization.
Chung MY, Cheng YKY, Yu SCH, Sahota DS,?Leung TY
Acta Obstet Gyn Scan 2014;92(11): 1250 - 1255
128 Patient's Choice between a Non-invasive Prenatal Test and Invasive Prenatal Diagnosis Based on Test Accuracy.
Chan OYM,?Leung TY, Chan OK, Cheng YKY, Sahota DS
Fetal Diagn Ther 2014;35(3): 193 - 198
129 Pelvic Floor Biometry during a First Singleton Pregnancy and the Relationship with Symptoms of Pelvic Floor Disorders: a Prospective Observational Study.
Chan SSC, Cheung RYK, Yiu AKW, Lee LLL,?Leung TY, Chung TKH
BJOG 2014;121(1): 121 - 129
130 Performance of Chromosomal Microarray for Patients with Intellectual Disabilities/Developmental Delay, Autism, and Multiple Congenital Anomalies in a Chinese Cohort.
Chong WS, Lo FM, Lam STS, Wang CC, Luk HM,?Leung TY, Choy KW
Mol Cytogenet 2014;7(34): 1 - 6
131 Prenatal Diagnosis of Maternally Inherited X-linked Opitz G/BBB Syndrome by Chromosomal Microarray in a Fetus with Complex Congenital Heart Disease.
Cheng YKY, Huang J, Law KM, Chan OYM,?Leung TY, Choy KW
Clin Chim Acta 2014;436C(2014): 140 - 142
132 Recurrent Structural Malformations Identified among Mowat?VWilson Syndrome Fetuses.
Zhou Y, Huang J, Cheng YKY,?Leung TY, Pooh RK, Lo FM, Choy KW
Prenatal Diag 2014;34(3): 296 - 298
133 Size-based Molecular Diagnostics Using Plasma DNA for Noninvasive Prenatal Testing.
Yu JCY, Chan AKC, Zheng YWL, Jiang PY, Liao GJW, Sun H, Akolekar R,?Leung TY, Go ATJI, van Vugt JMG, Minekawa R, Oudejans CBM, Nicolaides KH, Chiu RWK, Lo DYM
Proc Natl Acad Sci USA 2014;111(23): 8583 - 8588
134 Transcervical Intralesional Vasopressin Injection Compared with Placebo in Hysteroscopic Myomectomy.
Wong ASW, Cheung ECW, Yeung SW, Fan HL,?Leung TY, Sahota DS
Obstet Gynecol 2014;124(5): 897 - 903
135 Trends in Preterm Birth in Singleton Deliveries in a Hong Kong Population.
Hui ASY, Lao TTH,?Leung TY, Schaaf JM, Sahota DS
Int J Gynecol Obstet 2014;7292(14): 248 - 253
136 Can Live xPlane Imaging of the In-plane View of Interventricular Septum be Used to Detect Fetal Conotruncal Anomalies?
Xiong Y, Liu T, Gan HJ, Wu Y, Xu JF, Ting YH,?Leung TY, Lau TK
J Matern Fetal Neonatal Med 2013;26(4): 373 - 377
137 Cerclage Pessary for Preventing Preterm Birth in Women with a Singleton Pregnancy and a Short Cervix at 20 to 24 Weeks: A Randomized control_led Trial.
Hui ASY, Chor MCM, Lau TK, Lao TTH,?Leung TY
AM J Perinatol 2013;30(4): 283 - 288
138 Detection of the Fetal Conotruncal Anomalies Using Real-time Three-dimensional Echocardiography with Live Xplane Imaging of the Fetal Ductal Arch View.
Xiong Y, Liu T, Gan HJ, Wu Y, Xu JF, Ting YH,?Leung TY, Lau TK
Prenatal Diag 2013;33(5): 462 - 466
139 Environmental Factors in the First Trimester and Risk of Oral-Facial Clefts in the Offspring.
Chung MK, Lao TTH, Ting YH,?Leung TY, Lau TK, Wong TW
Reprod Sci 2013;20(7): 797 - 803
140 Feasibility and Safety Study of a New Device (Odon Device) for Assisted Vaginal Deliveries: Study Protocol.
The WHO Odon Device Research Group,?Leung TY
Reprod Health 2013;10(33): 1 - 8
141 First-trimester Cystic Hygroma: Relationship of Nuchal Translucency Thickness and Outcomes.
Huang J,?Leung TY, Choy KW
Obstet Gynecol 2013;121(1): 192 - 193
142 IL-15 and Macrophage Secretory Factors Facilitate Immune Activation of Neonatal Natural Killer Cells by Lipoteichoic Acid.
Cheng SF, Ho JWY, Chan KYY,?Leung TY, Lam HS, Fong ON, Li KKH, Ng PC
Cytokine 2013;61(2): 499 - 505
143 Impact of Neonatal Hepatitis B Vaccination Programme on Age-specific Prevalence of Hepatitis B Infection in Teenage Mothers in Hong Kong.
Lao TTH, Sahota DS, Suen SSH, Chan PKS,?Leung TY
Epidemiol Infect 2013;141(10): 2131 - 2139
144 Maternal Hepatitis B Surface Antigen Status and Incidence of Pre-eclampsia.
Lao TTH, Sahota DS, Cheng YKY, Law LW,?Leung TY
J Viral Hepatitis 2013;20(5): 343 - 349
145 Measuring the Angle of the Subpubic Arch Using Three-dimensional Transperineal Ultrasound Scan: Intraoperator Repeatability and Interoperator Reproducibility.
Choi PS, Chan SSC, Sahota DS,?Leung TY
AM J Perinatol 2013;30(3): 191 - 195
146 Motivations for Undertaking DNA Sequencing-based Non-invasive Prenatal Testing for Fetal Aneuploidy: A Qualitative Study with Early Adopter Patients in Hong Kong.
Yi H, Hallowell N, Griffiths S,?Leung TY
PLos ONE 2013;8(11): e81794
147 Noninvasive Prenatal Molecular Karyotyping from Maternal Plasma.
Yu JCY, Jiang PY, Choy KW, Chan AKC, Won HS, Leung WC, Lau ET, Tang MHY,?Leung TY, Lo DYM, Chiu RWK
PLos ONE 2013;8(4): e60968
148 Noninvasive Twin Zygosity Assessment and Aneuploidy Detection by Maternal Plasma DNA Sequencing.
Leung TY, Qu JZZ, Liao GJW, Jiang PY, Cheng YKY, Chan AKC, Chiu RWK, Lo DYM
Prenatal Diag 2013;33(7): 675 - 681
149 Nonremoval of an Abnormally Invasive Placenta at Cesarean Section with Postoperative Uterine Artery Embolization.
Chung MY, Cheng YKY, Yu SCH, Sahota DS,?Leung TY
Acta Obstet Gyn Scan 2013;92(11): 1250 - 1255
150 Prospective Assessment of the Hong Kong Hospital Authority Universal Down Syndrome Screening Programme.
Sahota DS, Leung WC, Chan WP, To WWK, Lau ET,?Leung TY
Hong Kong Med J 2013;19(2): 101 - 108
151 Radiofrequency Ablation for Selective Reduction in Complicated Monochorionic Multiple Pregnancies.
Lu J, Ting YH, Law KM, Lau TK,?Leung TY
Fetal Diagn Ther 2013;34(4): 211 - 216
152 Relationship between Age and Prevalence of Hepatitis B Infection in First-year University Students in Hong Kong.
Suen SSH, Lao TTH, Chan OK, Lau TK,?Leung TY, Chan PKS
Infection 2013;41(2): 529 - 535
153 Single Fetal Cells for Non-Invasive Prenatal Genetic Diagnosis: Old Myths New Prospective.
Chan WK, Kwok YKY, Choy KW,?Leung TY, Wang CC
Medical Journal of Obstetrics and Gynecology 2013;1(1): 1004
154 Spontaneous Carotid Cavernous Fistula Complicating Pregnancy.
Yeung SW, Suen SSH, Yu SCH, Lao TTH,?Leung TY, Lau TK
Hong Kong Med J 2013;19(3): 258 - 261
155 The Detection of Mosaicism by Prenatal BoBs TM.
Cheng YKY, Wong CKM, Wong HK, Leung Kwok On, Kwok YKY, Suen AKW, Wang CC,?Leung TY, Choy KW
Prenatal Diag 2013;33(1): 42 - 49
156 The Influence of Image Setting on Intracranial Translucency Measurement by Manual and Semi-automated System.
Zhen L, Yang X, Ting YH, Chen M,?Leung TY
Prenatal Diag 2013;33(9): 889 - 893
157 Timing of Caesarean Section According to Urgency.
Leung TY, Lao TTH
Best Pract Res Clin Obstet Gynaecol 2013;27(2): 251 - 267
158 Transcervical Intralesional Vasopressin Injection in Hysteroscopic Myomectomy-Description of a New Technique.
Wong ASW, Cheung ECW, Leung VKT, Yeung SW,?Leung TY, Fung TY
J Laparoendose Adv Surg Tech 2013;23(3): 258 - 262
159 Use of Birth Weight Threshold for Macrosomia to Identify Fetuses at Risk of Shoulder Dystocia among Chinese Populations.
Cheng YKY, Lao TTH, Sahota DS, Leung VKT,?Leung TY
Int J Gynecol Obstet 2013;120(3): 249 - 253
160 胎儿镜下激光凝固胎盘吻合血管术治疗双胎输血综合征33例临床分析.
Liu XX, Lau TK, Wang HF, Wong SM,?Leung TY
Chin J Obstet Gynecol 2012;47(8): 587 - 591
161 A Fetus with a Huge Neck Mass and a Large Abdominal Circumference - A Rare Case of Sialoblastoma and Hepatoblastoma.
Cheng YKY, Chu WCW, Law LW, Ting YH,?Leung TY
Prenatal Diag 2012;32(9): 915 - 917
162 A Novel Way of Visualizing the Ductal and Aortic Arches by Real-time Three-dimensional Ultrasound with Live xPlane Imaging.
Xiong Y, Chen M, Chan LW, Ting YH, Fung TY,?Leung TY, Lau TK
Ultrasound Obst Gyn 2012;39(3): 316 - 321
163 Arabin Cerclage Pessary in the Management of Cervical Insufficiency.
Ting YH, Lao TTH, Law LW, Hui ASY, Chor MCM, Lau TK,?Leung TY
J Matern Fetal Neonatal Med 2012;25(12): 2693 - 2695
164 Awareness and Knowledge of Hepatitis B Infection and Prevention and the Use of Hepatitis B Vaccination in the Hong Kong Adult Chinese Population.?
Chung JPW, Suen SSH, Chan OK, Lao TTH,?Leung TY
Chin Med J 2012;125(3): 422 - 427
165 Breastfeeding Initiation: Is this Influenced by Maternal Hepatitis B Infection?
Leung VKT, Lao TTH, Suen SSH, Chan OK, Sahota DS, Lau TK,?Leung TY
J Matern Fetal Neonatal Med 2012;25(11): 2390 - 2394
166 Can We Use the Frontomaxillary Facial Angle in the First Trimester to Predict Facial Cleft?
Pan M, Chen M, Sahota DS, Lao TTH, Lau TK,?Leung TY
Prenatal Diag 2012;32(5): 491 - 493
167 Cervical Pessary in Pregnant Women with a Short Cervix.
Hui ASY, Lao TTH, Ting YH,?Leung TY
Lancet 2012;380(9845): 887
168 Comparison of Real-time Three-Dimensional Echocardiography and Spatiotemporal Image Correlation in Assessment of Fetal Interventricular Septum.
Xiong Y, Liu T, Wu Y, Xu JF, Ting YH,?Leung TY, Lau TK
J Matern Fetal Neonatal Med 2012;25(11): 2333 - 2338
169 Deficient Knowledge on Hepatitis B Infection in Pregnant Women and Prevalence of Hepatitis B Surface Antigen Carriage in an Endemic Area: A Review.
Chan OK, Lao TTH, Suen SSH,?Leung TY
Hepat Res Treat 2012;2012: 317451
170 Effect of Image Settings on Nuchal Translucency Thickness Measurement by a Semi-automated System.
Chen PW, Chen M,?Leung TY, Lau TK
Ultrasound Obst Gyn 2012;39(2): 169 - 174
171 External Cephalic Version Does Not Increase the Risk of Intra-uterine Death: a 17-year Experience and Literature Review.
Leung VKT, Suen SSH, Sahota DS, Lau TK,?Leung TY
J Matern Fetal Neonatal Med 2012;25(9): 1774 - 1778
172 FetalQuant: Deducing Fractional Fetal DNA Concentration from Massively Parallel Sequencing of DNA in Maternal Plasma.
Jiang PY, Chan AKC, Liao GJW, Zheng YWL,?Leung TY, Chiu RWK, Lo DYM, Sun H
Bioinformatics 2012;28(22): 2883 - 2890
173 First Trimester Serum Markers Stability during Sample Transportation from the Obstetrical Site to the Screening Laboratory.
Sahota DS, Pooh RK, Choy KW,?Leung TY, Lau TK
J Matern Fetal Neonatal Med 2012;25(7): 966 - 969
174 Haemodynamic Effects from Aortocaval Compression at Different Angles of Lateral Tilt in Non-labouring Term Pregnant Women.
Lee SWY, Khaw KS, Ngan Kee WD,?Leung TY, Critchley LAH
Brit J Anaesth 2012;109(6): 950 - 956
175 Has Improved Health Care Provision Impacted on the Obstetric Outcome in Teenage Women?
Lao TTH, Suen SSH, Sahota DS, Law LW,?Leung TY
J Matern Fetal Neonatal Med 2012;25(8): 1358 - 1362
176 High Resolution Size Analysis of Fetal DNA in the Urine of Pregnant Women by Paired-end Massively Parallel Sequencing.
Tsui NBY, Jiang PY, Chow KCK, Su XX,?Leung TY, Sun H, Chan AKC, Chiu RWK, Lo DYM
PLos ONE 2012;7(10): e48319
177 Intrapleural Injection of OK-432 as the Primary In-utero Treatment for Fetal Chylothorax.
Leung VKT, Suen SSH, Ting YH, Law LW, Lau TK,?Leung TY
Hong Kong Med J 2012;18(2): 156 - 159
178 Maternal HBsAg Status and Infant Size - a Faustian Bargain?
Lao TTH, Sahota DS, Suen SSH, Law LW,?Leung TY
J Viral Hepatitis 2012;19(7): 519 - 524
179 Noninvasive Prenatal Diagnosis of Fetal Trisomy 21 by Allelic Ratio Analysis Using Targeted Massively Parallel Sequencing of Maternal Plasma DNA.
Liao GJW, Chan AKC, Jiang PY, Sun H,?Leung TY, Chiu RWK, Lo DYM
PLos ONE 2012;7(5): e38154
180 Normal Range of Intractranial Translucency (IT) Assessed by Three-dimensional Ultrasound at 11+0 to 13+6 Weeks in a Chinese Population.
Chen M, Chen H, Yang X, Wang HF,?Leung TY, Sahota DS, Lao TTH, Lau TK
J Matern Fetal Neonatal Med 2012;25(5): 489 - 492
181 Outcome of Monochorionic Twin Pregnancies with Abnormal Umbilical Artery Doppler between 16 and 20 Weeks of Gestation.
Pan M, Chen M,?Leung TY, Sahota DS, Ting YH, Lau TK
J Matern Fetal Neonatal Med 2012;25(3): 277 - 280
182 Prenatal Detection of Aneuploidy and Imbalanced Chromosomal Arrangements by Massively Parallel Sequencing.
Dan S, Chen F, Choy KW, Jiang FM, Lin JR, Xuan ZL, Wang W, Chen SP, Li XC, Jiang H,?Leung TY, Lau TK, Su Y, Zhang WY, Zhang XQ
PLos ONE 2012;7(2): e27835
183 Prevalence of Levator Ani Muscle Injury in Chinese Women after First Delivery.
Chan SSC, Cheung RYK, Yiu AKW, Lee LLL, Pang WL, Choy KW,?Leung TY, Chung TKH
Ultrasound Obst Gyn 2012;39(6): 704 - 709
184 Quality Assurance of Nuchal Translucency for Prenatal Fetal Down Syndrome Screening.
Sahota DS, Leung WC, To WWK, Chan WP, Lau TK,?Leung TY
J Matern Fetal Neonatal Med 2012;25(7): 1039 - 1043
185 Scan the Fetal Heart by Real-time Three-dimensional Echocardiography with Live xPlane Imaging.
Xiong Y, Chen M, Chan LW, Ting YH, Fung TY,?Leung TY, Lau TK
J Matern Fetal Neonatal Med 2012;25(4): 324 - 328
186 Successful Treatment of Severe Fetal Chylothorax Resistant to Repeated Pleuroamniotic Shunting by OK-432 Pleurodesis.
Lo TK, Lau WL, Lam YY, Tang MHY,?Leung TY, Leung WC
Fetal Diagn Ther 2012;31(4): 260 - 263
187 Systematic Identification of Spontaneous Preterm Birth-Associated RNA Transcripts in Maternal Plasma.
Chim SSC, Lee WS, Ting YH, Chan OK, Lee SWY,?Leung TY
PLos ONE 2012;7(4): e34328
188 Technical Concerns about Immunoprecipitation of Methylated Fetal DNA for Noninvasive Trisomy 21 Diagnosis.
Tong YK, Chiu RWK, Chan AKC,?Leung TY, Lo DYM
Nat Med 2012;18(9): 1327 - 1328
189 Thalassaemia in Pregnancy.
Leung TY, Lao TTH
Best Pract Res Clin Obstet Gynaecol 2012;26(1): 37 - 51
190 The Force Applied to Successfully Turn a Foetus during Reattempts of External Cephalic Version is Substantially Reduced When Performed under Spinal Analgesia.
Suen SSH, Khaw KS, Law LW, Sahota DS, Lee SWY, Lau TK,?Leung TY
J Matern Fetal Neonatal Med 2012;25(6): 719 - 722
191 2010 Report from the ISPD Special Interest Groups.
Odibo AO, Faas BHW, Oepkes D,?Leung TY, Lee SM
Prenatal Diag 2011;31: 246 - 248
192 Assessment of Sonographer Nuchal Translucency Measurement Performance - Central Tendency and Dispersion.
Sahota DS, Chen M,?Leung TY, Chan LW, Fung TY, Ting YH, Lau TK
J Matern Fetal Neonatal Med 2011;24(6): 812 - 816
193 Comparison of Perinatal Outcomes of Shoulder Dystocia Alleviated by Different Type and Sequence of Manoeuvres: a Retrospective Review.
Leung TY, Stuart O, Suen SSH, Sahota DS, Lau TK, Lao TTH
BJOG 2011;118(8): 985 - 990
194 Correlation between Maternal Hepatitis B Surface Antigen Carrier Status with Social, Medical and Family Factors in an Endemic Area: Have We Overlooked Something?
Chan OK, Lao TTH, Suen SSH, Lau TK,?Leung TY
Infection 2011;39(5): 419 - 426
195 Do Prior Contraceptive Methods Impact Maternal Carriage in Patients with Hepatitis B?
Lao TTH, Chan OK, Suen SSH,?Leung TY
Hepat Mon 2011;11(10): 829 - 834
196 Frontomaxillary Facial Angle at 11+0 to 13+6 Weeks in Chinese Population.
Chen M, Wang HF,?Leung TY, Sahota DS, Borenstein M, Nicolaides KH, Lao TTH, Lau TK
J Matern Fetal Neonatal Med 2011;24(3): 498 - 501
197 Head-To-Body Delivery Interval And Risk of Fetal Acidosis and Hypoxic Ischaemic Encephalopathy in Shoulder Dystocia: A Retrospective Review.
Leung TY, Stuart O, Sahota DS, Suen SSH, Lau TK, Lao TTH
BJOG 2011;118(4): 474 - 479
198 Identification of Submicroscopic Chromosomal Aberrations in Fetuses with increased Nuchal Translucency and Apparently Normal Karyotype.
Leung TY, Vogel I, Lau TK, Chong WS, Hyett JA, Petersen OB, Choy KW
Ultrasound Obst Gyn 2011;38(3): 314 - 319
199 Influx of Mainland Expectant Mothers: a Blessing or a Curse?
Leung TY, Lao TTH
HKJGOM 2011;11(1): 9 - 10
200 Isolated Absent or Hypoplastic Nasal Bone in the Second Trimester Fetus: is Amniocentesis Necessary?
Ting YH, Lao TTH, Lau TK, Chung MK,?Leung TY
J Matern Fetal Neonatal Med 2011;24(4): 555 - 558
201 Knowledge on Hepatitis B Infection among Pregnant Women in a High Endemicity Area.
Chan OK, Lao TTH, Suen SSH, Lau TK,?Leung TY
Patient Educ and Couns 2011;85(3): 516 - 520
202 Maternal Understanding of Commercial Cord Blood Storage for Their Offspring - A Survey among Pregnant Women in Hong Kong.
Suen SSH, Lao TTH, Chan OK, Kou TKO, Chan CS, Kim JH, Lau TK,?Leung TY
Acta Obstet Gyn Scan 2011;90(9): 1005 - 1009
203 Non-Invasive Prenatal Assessment of Trisomy 21 by Multiplexed Maternal Plasma DNA Sequencing : Large Scale Validity Study.
Chiu RWK, Akolekar R, Zheng YWL,?Leung TY, Sun H, Chan AKC, Lun FMF, Go ATJI, Lau ET, To WWK, Leung WC, Tang RYK, Au Yeung KC, Lam H, Kung YY, Zhang XQ, Van Vugt JMG, Minekawa R, Tang MHY, Wang J, Oudejans CBM, Lau TK, Nicolaides KH, Lo DYM
Brit Med J 2011;342: c7401
204 Noninvasive Prenatal Diagnosis of Fetal Trisomy 18 and Trisomy 13 by Maternal Plasma DNA Sequencing.?
Chen EZ, Chiu RWK, Sun H, Akolekar R, Chan AKC,?Leung TY, Jiang PY, Zheng YWL, Lun FMF, Chan LYS, Jin YJ, Go ATJI, Lau ET, To WWK, Leung WC, Tang RYK, Au Yeung KC, Lam H, Kung YY, Wang J, Van Vugt JMG, Minekawa R, Tang MHY, Wang J, Oudejans CBM, Lau TK, Nicolaides KH, Lo DYM
PLos ONE 2011;6(7): e21791
205 Noninvasive Prenatal Diagnosis of Hemophilia by Microfluidics Digital PCR Analysis of Maternal Plasma DNA.
Tsui NBY, Kadir RA, Chan AKC, Chi C, Mellars G, Tuddenham EG,?Leung TY, Lau TK, Chiu RWK, Lo DYM
Blood 2011;117(13): 3684 - 3691
206 Placental Site in The Second Trimester of Pregnancy and Its Association with Subsequent Obstetric Outcome.
Fung TY, Sahota DS, Lau TK,?Leung TY, Chan LW, Chung TKH
Prenatal Diag 2011;31(6): 548 - 554
207 Prenatal Diagnosis of Morbidly Adherent Placenta.
Lau TK,?Leung TY
Int J Obstet Anesth 2011;20(2): 107 - 109
208 Seroprevalence of Varicella Zoster Virus among Pregnant Women in Hong Kong: Comparison with Self-reported History.?
Fung LWY, Lao TTH, Suen SSH, Chan OK, Lau TK, Ngai LK, Chan PKS,?Leung TY
Vaccine 2011;29(46): 8186 - 8188
209 Serum Placental Growth Factor and Fms-like Tyrosine Kinase 1 during First Trimester in Chinese Women with Pre-eclampsia - A Case-control_ Study.
Law LW, Sahota DS, Chan LW, Chen M, Lau TK,?Leung TY
J Matern Fetal Neonatal Med 2011;24(6): 808 - 811
210 Stem Cell-Like Properties of Human Umbilical Cord Lining Epithelial Cells and the Potential for Epidermal Reconstitution.
Huang L, Wong YP, Gu H, Cai YJ, Ho Y, Wang CC,?Leung TY, Burd A
Cytotherapy 2011;13(2): 145 - 155
211 The Impact of Fetal Gender on Preterm Birth in a Southern Chinese Population.
Lao TTH, Sahota DS, Suen SSH, Law LW,?Leung TY
J Matern Fetal Neonatal Med 2011;24(12): 1440 - 1443
212 The Use of Three-Dimensional Ultrasound Does Not Improve Training in Fetal Biometric Measurements.
Chan LW, Ting YH, Lao TTH, Chau MMC, Fung TY,?Leung TY, Sahota DS, Lau TK
J Matern Fetal Neonatal Med 2011;24(9): 1173 - 1175
213 Use of Three-Dimensional (3D) Sonography to Assess the True Midsagittal Plane of Fetal Spine.
Yang XH, Chen M,?Leung TY, Wong SM, Lau TK
J Matern Fetal Neonatal Med 2011;24(2): 297 - 300
214 唐氏综合征的产前筛查模式和临床应用.
Lau TK,?Leung TY, Chen M, Liao C
Chin J Obstet Gynecol 2010;45(6)
215 唐氏综合症的产前诊断.
Lau TK,?Leung TY, Chen M, Liao C
Chin J Obstet Gynecol 2010;45(10): 732 - 734
216 Assessment of the Fetal Interventricular Septum Using Real-Time Three-Dimensional Echocardiography with Live 3D Imaging.
Xiong Y, Wah IYM, Chen M, Fung TY,?Leung TY, Lau TK
Ultrasound Obst Gyn 2010;35(6): 754 - 755
217 Chronic Hepatitis B Virus Infection and Rubella Susceptibility in Pregnant Women.
Lao TTH, Sahota DS, Suen SSH, Lau TK,?Leung TY
J Viral Hepatitis 2010;17(10): 737 - 741
218 Classification of Pathogenic or Benign Status of CNVs Detected by microarray Analysis.?
Leung TY, Pooh RK, Wang CC, Lau TK, Choy KW
Expert Rev Mol Diagn 2010;10(6): 717 - 721
219 Comparison of First-Trimester Contingent Screening Strategies for Down Syndrome.
Sahota DS,?Leung TY, Chan LW, Law LW, Fung TY, Chen M, Lau TK
Ultrasound Obst Gyn 2010;35(3): 286 - 291
220 Comparison of Likehood Ratios of First-Trimester Nuchal Translucency Measurements: Multiples of Median, Delta or Mixture.
Sahota DS,?Leung TY, Chen M, Chan LW, Fung TY, Lau TK
Ultrasound Obst Gyn 2010;36(1): 15 - 19
221 Effect of Long-Term Storage on Placental Growth Factor and FMS-Like Tyrosine Kinase 1 Measurements in Samples from Pregnant Women.
Law LW, Sahota DS, Chan LW, Chen M, Lau TK,?Leung TY
J Matern Fetal Neonatal Med 2010;23(12): 1475 - 1480
222 Epigenetic-Genetic Chromosome Dosage Approach for Fetal Trisomy 21 Detection Using an Autosomal Genetic Reference Marker.
Tong YK, Chiu RWK, Akolekar R,?Leung TY, Lau TK, Nicolaides KH, Lo DYM
PLos ONE 2010;5(12): e15244
223 Fetoscopic Laser Photocoagulation in the Management of Twin-Twin Transfusion Syndrome: Local Experience from Hong Kong.?
Yang X,?Leung TY, Ngan Kee WD, Chen M, Chan LW, Lau TK
Hong Kong Med J 2010;16(4): 275 - 281
224 Hepatitis B Infection and Outcomes of In Vitro Fertilization and Embryo Transfer Treatment.
Lam PM, Suen SSH, Lao TTH, Cheung LP,?Leung TY, Haines CJ
Fertil Steril 2010;93(2): 480 - 485
225 Implications of the Relationship Between Maternal Age and Parity with Hepatitis B Carrier Status in a High Endemicity Area.
Suen SSH, Lao TTH, Sahota DS, Lau TK,?Leung TY
J Viral Hepatitis 2010;17(5): 372 - 378
226 Learning Curve in Measurement of Fetal Frontomaxillary Facial Angle at 11-13 Weeks of Gestation.
Yang X, Chen M, Wang HF,?Leung TY, Borenstein M, Nicolaides KH, Sahota DS, Lau TK
Ultrasound Obst Gyn 2010;35(5): 530 - 534
227 Massive Subchorionic Thrombohematoma: a Series of 10 Cases.?
Fung TY, To KF, Sahota DS, Chan LW,?Leung TY, Lau TK
Acta Obstet Gyn Scan 2010;89(10): 1357 - 1361
228 Maternal Plasma DNA Sequencing Reveals the Genome-Wide Genetic and Mutational Profile of the Fetus.
Lo DYM, Chan AKC, Sun H, Chen EZ, Jiang PY, Lun FMF, Zheng YWL,?Leung TY, Lau TK, Cantor CR, Chiu RWK
Sci Transl Med 2010;2(61): 61ra91
229 Nausea and Vomiting in Health-Related Quality of Life among Chinese Pregnant Women.
Chan OK, Sahota DS,?Leung TY, Chan LW, Fung TY, Lau TK
Aust NZ J Obstet Gyn 2010;50(6): 512 - 518
230 Outcome of Induction of Labour Using Maternal Characteristics, Ultrasound Assessment and Biochemical State of the Cervix.?
Cheung ECW,?Leung TY, Sahota DS, Chan OK, Chan LW, Fung TY, Lau TK
J Matern Fetal Neonatal Med 2010;23(12): 1406 - 1412
231 Randomised Trial of Assigned Mode of Delivery after a Previous Cesarean Section-Impact on Maternal Psychological Dynamics.
Law LW, Pang MW, Chung TKH, Lao TTH, Lee DTS,?Leung TY, Sahota DS, Lau TK
J Matern Fetal Neonatal Med 2010;23(10): 1106 - 1113
232 Real-Time Three-Dimensional Ultrasound with Live xPlane Imaging Assists First-Trimester Acquisition of a True Midsagittal Section.?
Xiong Y, Wah IYM, Chan LW,?Leung TY, Fung TY, Lau TK
Ultrasound Obst Gyn 2010;36(2): 136 - 140
233 Second-Trimester Detection of Mowat-Wilson Syndrome Using Comparative Genomic Hybridization Microarray Testing.
Choy KW, To KF, Chan AWH, Lau TK,?Leung TY
Obstet Gynecol 2010;115(2): 462 - 465
234 Systematic Identification of Placental Epigenetic Signatures for the Noninvasive Prenatal Detection of Edwards Syndrome.
Tsui DWY, Lam DYM, Lee CWS,?Leung TY, Lau TK, Lau ET, Tang MHY, Akolekar R, Nicolaides KH, Chiu RWK, Lo DYM, Chim SSC
PLos ONE 2010;5(11): e15069
235 Tyrosinase Gene (TYR) Mutations in Chinese Patients with Oculocutaneous Albinism Type 1.
Liu J, Choy KW, Chan LWL,?Leung TY, Tam POS, Chiang WY, Lam DSC, Pang CCP, Lai TYY
Clin Exp Ophthalmol 2010;38(1): 37 - 42
236 Universal Rubella Vaccination Programme and Maternal Rubella Immune Status: A Tale of Two Systems.
Lao TTH, Suen SSH,?Leung TY, Sahota DS, Lau TK
Vaccine 2010;28(10): 2227 - 2230
237 Use of Hemostatic Gel in Postpartum Hemorrhage Due to Placenta Previa.
Law LW, Chor MCM,?Leung TY
Obstet Gynecol 2010;116(12): 528 - 530
238 A strategy for identifying circulating placental RNA markers for fetal growth assessment.
Pang WWI, Tsui MHY, Sahota DS,?Leung TY, Lau TK, Lo DYM, Chiu Rossa WK
Prenatal Diag 2009;29(5): 495 - 504
239 A survey of prenatal first-trimester aneuploidy screening among Hong Kong specialist obstetricians.
Chan OYM, Sahota DS, Chan OK,?Leung TY, Lau TK
Hong Kong Med J 2009;15(6): 447 - 451
240 Chinese women's preferences for prenatal diagnostic procedure and their willingness to trade between procedures.
Chan OYM, Sahota DS,?Leung TY, Choy KW, Chan OK, Lau TK
Prenatal Diag 2009;29(13): 1270 - 1276
241 De novo 16p13.11 microdeletion identified by high-resolution array CGH in a fetus with increased nuchal translucency.
Law LW, Lau TK, Fung TY,?Leung TY, Wang CC, Choy KW
BJOG 2009;116(2): 339 - 343
242 Determinants of hepatitis B vaccine uptake among pregnant Chinese women in Hong Kong.
Chan OK, Suen SSH, Lao TTH, Leung VKT, Yeung SW,?Leung TY
Int J Gynecol Obstet 2009;106(3): 232 - 235
243 Determination of Individual Preference: Why, How and Alternatives.
Sahota DS,?Leung TY, Lau TK
Fetal and Maternal Medicine Review 2009;20(4): 301 - 317
244 Development of extraction protocols to improve the yield for fetal RNA in maternal plasma.
Heung MS, Tsui NBY,?Leung TY, Lau TK, Lo DYM, Chiu Rossa WK
Prenatal Diag 2009;29(3): 277 - 279
245 Fetal crown-rump length and estimation of gestational age in an ethnic Chinese population.
Sahota DS,?Leung TY, Leung TN, Chan OK, Lau TK
Ultrasound Obst Gyn 2009;33(2): 157 - 160
246 First Trimester Combined Screening for Trisomy 21 in Hong Kong: Outcome of the First 10000 Cases.
Leung TY, Chan LW, Law LW, Sahota DS, Fung TY, Leung TN, Lau TK
J Matern Fetal Neonatal Med 2009;22(4): 300 - 304
247 First trimester measurements of nasal bone length using three-dimensional ultrasound.
Chen M, Wang HF,?Leung TY, Fung TY, Chan LW, Sahota DS, Lao TTH, Lau TK
Prenatal Diag 2009;29(8): 766 - 770
248 First-trimester fetal nasal bone length in an ethnic Chinese population.
Sahota DS,?Leung TY, Chan LW, Law LW, Fung TY, Chan OK, Lau TK
Ultrasound Obst Gyn 2009;34(1): 33 - 37
249 Gastroschisis Associated with an Intra-abdominal Umbilical Vein Varix: A Report of 2 Cases.
Fung TY, Chan LW,?Leung TY, Lau TK
Fetal Diagn Ther 2009;25(4): 404 - 406
250 Is the policy of restrictive episiotomy generalisable? A prospective observational study.
Lai CY, Cheung HW, Lao TTH, Lau TK,?Leung TY
J Matern Fetal Neonatal Med 2009;22(12): 1116 - 1121
251 Medians and correction factors for biochemical and ultrasound markers in Chinese women undergoing first-trimester screening for trisomy 21.
Sahota DS,?Leung TY, Fung TY, Chan LW, Law LW, Lau TK
Ultrasound Obst Gyn 2009;33(4): 387 - 393
252 Miscarriage after invasive prenatal diagnostic procedures: how much risk our pregnant women are willing to take?
Chan OYM, Sahota DS, Chan OK,?Leung TY, Lau TK
Prenatal Diag 2009;29(9): 870 - 874
253 Non-invasive Prenatal Detection of Fetal Trisomy 18 by RNA-SNP Allelic Ratio Analysis Using Maternal Plasma SERPINB2 mRNA: a Feasibility Study.
Tsui NBY, Wong CK,?Leung TY, Lau TK, Chiu RWK, Lo DYM
Prenatal Diag 2009;29(11): 1031 - 1037
254 Non-invasive Prenatal Diagnosis: From Dream to Reality.
Lau TK,?Leung TY
JPOG 2009;35(3): 125 - 131
255 Placenta-derived fetal specific mRNA is more readily detectable in maternal plasma than in whole blood.
Heung MS, Jin SN, Tsui NBY, Ding CM,?Leung TY, Lau TK, Chiu Rossa WK, Lo DYM
PLos ONE 2009;4(6): e5858
256 Prenatal findings and delineation of de novo concurrent partial trisomy 7q(7q31.2 --> qter) and partial monosomy 6q(6q26 --> qter) by high-resolution array CGH.
Choy KW, Chan LW, Tang MHY, Ng LKI,?Leung TY, Lau TK
J Matern Fetal Neonatal Med 2009;22(11): 1014 - 1020
257 Real-time three-dimensional echocardiography using a matrix probe with live xPlane imaging of the interventricular septum.
Xiong Y, Wah IYM, Chen M,?Leung TY, Lau TK
Ultrasound Obst Gyn 2009;34(5): 534 - 537
258 Role of monoamine oxidases in the exaggerated 5-hydroxytryptamine-induced tension development of human isolated preeclamptic umbilical artery.
Seto SW, Lam HY, Lau WS, Au ALS, Lam TY, Chim SSC, Ngai SSM, Chan SW,?Leung TY, Yeung JHK, Kong SK, Leung GPH, Lee SMY, Kwan YW
Eur J Pharmacol 2009;605(1-3): 129 - 137
259 Severe Chronic Morbidity following Childbirth.
Leung TY, Chung TKH
Best Pract Res Clin Obstet Gynaecol 2009;23(3): 401 - 423
260 Sociodemographic factors and pregnancy events associated with women who declined vaginal birth after cesarean section.
Pang MW, Law LW,?Leung TY, Lai BPY, Lau TK
Eur J Obstet Gyn R B 2009;143(1): 24 - 28
261 Study on the applicability of frontomaxillary facial angle in the first-trimester trisomy 21 fetuses in Chinese population.
Chen M, Yang X,?Leung TY, Sahota DS, Fung TY, Chan LW, Lao TTH, Lau TK
Prenatal Diag 2009;29(12): 1141 - 1144
262 Ultrasound screening for fetal structural abnormalities performed by trained midwives in the second trimester in a low-risk population-an appraisal.
Chen M,?Leung TY, Sahota DS, Fung TY, Chan LW, Law LW, Chau MMC, Lao TTH, Lau TK
Acta Obstet Gyn Scan 2009;88(6): 713 - 719
263 Urgent Cesarean Delivery for Fetal Bradycardia.
Leung TY, Chung JPW, Rogers MS, Sahota DS, Lao TTH, Chung TKH
Obstet Gynecol 2009;114(5): 1023 - 1028
264 Volumetric (3D) imaging reduces inter- and intraobserver variation of fetal biometry measurements.
Chan LW, Fung TY,?Leung TY, Sahota DS, Lau TK
Ultrasound Obst Gyn 2009;33(4): 447 - 452
265 Which Ultrasound or Biochemical Markers are Independent Predictors of Small-for-Gestational Age?
Law LW,?Leung TY, Sahota DS, Chan LW, Fung TY, Lau TK
Ultrasound Obst Gyn 2009;34(3): 283 - 287
266 Customized birth weight: coefficients and validation of models in a UK population.
Sahota DS, Kagan KO, Lau TK,?Leung TY, Nicolaides KH
Ultrasound Obst Gyn 2008;32(7): 884 - 889
267 Expectation and Knowledge of Pregnant Women Undergoing First and Second Trimester Ultrasound Examination in a Chinese Population.
Chan LW, Chan OK, Chau MMC, Sahota DS,?Leung TY, Fung TY, Lau TK
Prenatal Diag 2008;28(8): 739 - 744
268 Fetal Biometry in Ethnic Chinese: Biparietal Diameter, Head Circumference, Abdominal Circumference and Femur Length.
Leung TN, Pang MW, Sahota DS,?Leung TY, Poon CF, Wong SM, Lau TK
Ultrasound Obst Gyn 2008;31(3): 321 - 327
269 Fetal nasal bone status in Chinese women undergoing first-trimester screening for trisomy 21.
Leung TY, Sahota DS, Chan LW, Law LW, Fung TY, Lau TK
Am J Obstet Gynecol 2008;199(5): 521.e1 - 521.e5
270 How true is a 'true' midsagittal section?
Wah IYM, Chan LW,?Leung TY, Fung TY, Lau TK
Ultrasound Obst Gyn 2008;32(7): 855 - 859
271 Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma.
Chiu Rossa WK, Chan AKC, Gao Y, Lau VYM, Zheng W,?Leung TY, Foo CHF, Xie B, Tsui NBY, Lun FMF, Zee BCY, Lau TK, Cantor CR, Lo DYM
Proc Natl Acad Sci USA 2008;105(51): 20458 - 20463
272 Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma.
Lun FMF, Tsui NBY, Chan AKC,?Leung TY, Lau TK, Charoenkwan P, Chow KCK, Lo WYW, Wanapirak C, Sanguansermsri T, Cantor CR, Chiu Rossa WK, Lo DYM
Proc Natl Acad Sci USA 2008;105(50): 19920 - 19925
273 Prediction of birth weight by fetal crown-rump length and maternal serum levels of pregnancy-associated plasma protein-A in the first trimester.
Leung TY, Sahota DS, Chan LW, Law LW, Fung TY, Leung TN, Lau TK
Ultrasound Obst Gyn 2008;31(1): 10 - 14
274 Repeat Antenatal Corticosteroids: Should it be Prescribed and if so when and how?
Leung TY, Sahota DS
Fetal and Maternal Medicine Review 2008;19(2): 165 - 180
275 Side-Effect and Vital Sign Profile of Nifedipine as a Tocolytic for Preterm Labour.
Chan LW, Sahota DS, Yeung SY,?Leung TY, Fung TY, Lau TK, Leung TN
Hong Kong Med J 2008;14(4): 267 - 272
276 The Application of Microarray Based Comparative Genomic Hybridization in Prenatal Diagnosis.
Choy KW, Tsang PT,?Leung TY, Wang CC, Lau TK
Fetal and Maternal Medicine Review 2008;19(2): 119 - 133
277 Trends in Maternal Obesity and Associated Risks of Adverse Pregnancy Outcomes in a Population of Chinese Women.
Leung TY, Leung TN, Sahota DS, Chan OK, Chan LW, Fung TY, Lau TK
BJOG 2008;115(12): 1529 - 1537
278 Umbilical cord ulceration causing foetal haemorrhage and stillbirth.
Chan SSC, Lau APK, To KF,?Leung TY, Lau TK, Leung TN
Hong Kong Med J 2008;14(2): 148 - 151
279 A longitudinal observational study of preference for elective caesarean section among nulliparous Hong Kong Chinese women.
Pang MW, Lee DTS, Leung AKL,?Leung TY, Lau TK, Leung TN
BJOG 2007;114(5): 623 - 629
280 Determinants of preference for elective caesarean section in Hong Kong Chinese pregnant women.
Pang MW, Leung TN,?Leung TY, Lai CY, Lau TK, Chung TKH
Hong Kong Med J 2007;13(2): 100 - 105
281 Digital PCR for the molecular detection of fetal chromosomal aneuploidy.
Lo DYM, Lun FMF, Chan AKC, Tsui NBY, Chong KC, Lau TK,?Leung TY, Zee BCY, Cantor CR, Chiu Rossa WK
Proc Natl Acad Sci USA 2007;104(32): 13116 - 13121
282 Fetal parvovirus B19 infection in a twin pregnancy with 1 twin presenting with hydrops fetalis and the other asymptomatic: a case report.
Leung TN,?Leung TY, Chan PKS, Fung TY, Lau TK
J Reprod Med 2007;52(5): 419 - 421
283 First-trimester combined screening for trisomy 21 in a predominantly Chinese population.
Leung TY, Chan LW, Leung TN, Fung TY, Sahota DS, Spencer K, Lau TK
Ultrasound Obst Gyn 2007;29(1): 14 - 17
284 Foetal intracranial teratoma: choosing the best time and mode of delivery.
Chan LW,?Leung TY, Leung TN, Fung TY, Lau TK
Hong Kong Med J 2007;13(4): 323 - 326
285 Quantitative aberrations of hypermethylated RASSF1A gene sequences in maternal plasma in pre-eclampsia.
Tsui DWY, Chan AKC, Chim SSC, Chan LW,?Leung TY, Lau TK, Lo DYM, Chiu Rossa WK
Prenatal Diag 2007;27(13): 1212 - 1218
286 Dextrocardia in pregnancy: 20 years experience.
Fung TY, Chan LW, Leung TN,?Leung TY, Lau TK
J Reprod Med 2006;51(7): 573 - 577
287 First-trimester maternal serum level of pregnancy-associated plasma protein-A is an independent predictor of fetal maxillary bone length.
Leung TY, Chan LW, Leung TN, Fung TY, Sahota DS, Lau TK
Ultrasound Obst Gyn 2006;27(1): 9 - 12
288 First-trimester maternal serum levels of placental hormones are independent predictors of second-trimester fetal growth parameters.
Leung TY, Chan LW, Leung TN, Fung TY, Sahota DS, Lau TK
Ultrasound Obst Gyn 2006;27(2): 156 - 161
289 Prediction of intrapartum Cesarean delivery for non-reassuring fetal status after a successful external cephalic version by a low pre-version pulsatility index of the fetal middle cerebral artery.
Leung TY, Fok AWY, Chan LW, Law LW, Lau TK
Ultrasound Obst Gyn 2006;27(4): 416 - 419
290 Risk factors for procedure-related fetal losses after mid-trimester genetic amniocentesis.
Kong CW, Leung TN,?Leung TY, Chan LW, Sahota DS, Fung TY, Lau TK
Prenatal Diag 2006;26(10): 925 - 930
291 The utility assessment of Chinese pregnant women towards the birth of a baby with Down syndrome compared to a procedure-related miscarriage.
Chan YM, Leung TN,?Leung TY, Fung TY, Chan LW, Lau TK
Prenatal Diag 2006;26(9): 819 - 824
292 Variation of force applied during external cephalic version with different patients' characteristic and outcome of version.
Leung TY, Sahota DS, Chan LW, Fok AWY, Law LW, Lau TK
Acta Obstet Gyn Scan 2006;85(2): 182 - 187
293 Cervical length at 18 - 22 weeks of gestation for prediction of spontaneous preterm delivery in Hong Kong Chinese women.
Leung TN, Pang MW,?Leung TY, Poon CF, Wong SM, Lau TK
Ultrasound Obst Gyn 2005;26(7): 713 - 717
294 Effect of prostaglandin E2 for cervical priming on fetal hemodynamics.
Fok AWY,?Leung TY, Tsui MHY, Leung TN, Lau TK
J Reprod Med 2005;50(9): 697 - 700
295 Expectation and knowledge of women undergoing first-trimester combined screening for Down syndrome in a Chinese population.
Chan LW, Chau MMC,?Leung TY, Fung TY, Leung TN, Lau TK
Prenatal Diag 2005;25(13): 1248 - 1252
296 Fetal hemodynamic changes after amniotomy.
Fok AWY,?Leung TY, Tsui MHY, Leung TN, Lau TK
Acta Obstet Gyn Scan 2005;84(2): 166 - 169
297 Fetal intra-abdominal umbilical vein varix: what is the clinical significance?
Fung TY, Leung TN,?Leung TY, Lau TK
Ultrasound Obst Gyn 2005;25(2): 149 - 154
298 Higher median levels of free beta-hCG and PAPP-A in the first trimester of pregnancy in a Chinese ethnic group. Implication for first trimester combined screening for Down's syndrome in the Chinese population.
Leung TY, Spencer K, Leung TN, Fung TY, Lau TK
Fetal Diagn Ther 2005;21(1): 140 - 143
299 Maternal experience of pain during external cephalic version at term.
Fok AWY, Chan LW,?Leung TY, Lau TK
Acta Obstet Gyn Scan 2005;84(8): 748 - 751
300 Outcome of 1355 consecutive transabdominal chorionic villus samplings in 1351 patients.
Lau TK,?Leung TY, Fung TY, Chan LW, Sahota DS, Leung TN
Chin Med J 2005;118(20): 1675 - 1681
301 Prediction of Outcome of External Cephalic Version for Breech Presentation at Term.
Leung TY, Lau TK
Fetal and Maternal Medicine Review 2005;16(3): 245 - 262
302 Prenatal embolisation of a large chorioangioma using enbucrilate.
Lau TK, Yu SCH,?Leung TY, To KF, Fung TY, Leung TN
BJOG 2005;112(7): 1002 - 1004
303 Attitudes towards termination of pregnancy among Hong Kong Chinese women attending prenatal diagnosis counselling clinic.
Leung TN, Chau MMC, Chang JJHT,?Leung TY, Fung TY, Lau TK
Prenatal Diag 2004;24(7): 546 - 551
304 Cord blood acid-base status at delivery after successful external cephalic version.
Chan Louis YS,?Leung TY, Fok AWY, Chan LW, Lau TK
Acta Obstet Gyn Scan 2004;83(5): 436 - 439
305 Deterioration in cord blood gas status during the second stage of labour is more rapid in the second twin than in the first twin.
Leung TY, Lok IH, Tam WH, Leung TN, Lau TK
BJOG 2004;111(6): 546 - 549
306 External cephalic version induced fetal cerebral and umbilical blood flow changes are related to the amount of pressure exerted.
Leung TY, Sahota DS, Fok AWY, Chan LW, Lau TK
BJOG 2004;111(5): 430 - 435
307 Prediction of successful vaginal delivery in women undergoing external cephalic version at term for breech presentation.
Chan Louis YS,?Leung TY, Fok AWY, Chan LW, Lau TK
Eur J Obstet Gyn R B 2004;116(1): 39 - 42
308 Treatment of twin-twin transfusion syndrome by fetoscopic laser photocoagulation.
Lau TK,?Leung TY, Fung TY, Leung TN
Chin Med J 2004;117(9): 1431 - 1434
309 Fetus with Hydropic Change Secondary to Fetal Supraventricular Tachycardia.
Yam MC,?Leung TY, Lau TK, Sung RYT
HK J Paediatr 2003;8(2): 130 - 132
310 Prenatal Treatment of Chorioangioma by Microcoil Embolisation.
Lau TK,?Leung TY, Yu SCH, To KF, Leung TN
BJOG 2003;110(1): 70 - 73
311 Quantification of contact surface pressure exerted during external cephalic version.
Leung TY, Sahota DS, Fok AWY, Chan LW, Lau TK
Acta Obstet Gyn Scan 2003;82(11): 1017 - 1022
312 Effect of twin-to-twin delivery interval on umbilical cord blood gas in the second twins.
Leung TY, Tam WH, Leung TN, Lok IH, Lau TK
BJOG 2002;109(1): 63 - 67
313 High incidence of obstetric interventions after successful external cephalic version.
Chan Louis YS,?Leung TY, Fok AWY, Chan LW, Lau TK
BJOG 2002;109(6): 627 - 631
314 A 2-year Audit of a Midwife-based Obstetric Ultrasound Service.
Poon CF, Wong SM, Ng SC, Chau MMC,?Leung TY, Leung TN, Lau TK
HKJGOM 2001;2(2): 73 - 79
315 Fetal scalp cysts: challenge in diagnosis and counseling.
Lau TK, Leung TN,?Leung TY, Pang MW, Tam WH
J Ultras Med 2001;20(2): 175 - 177
316 Prenatal Diagnosis of Intra-abdominal Mature Testicular Teratoma.
Siu NSS, Leung TN,?Leung TY, Ng SW, Yeung CK, Lau TK
J Ultras Med 2001;20(11): 1257 - 1260
317 Rare major maternal complications after second trimester amniocentesis: sequelae of avoiding a transplacental approach.
Lau TK, Leung TN,?Leung TY, Pang MW, Tam WH
Aust NZ J Obstet Gyn 2001;41(4): 472 - 473
318 Risk and Prediction of Preterm Delivery in Pregnancies Complicated by Antepartum Hemorrhage of Unknown Origin before 34 Weeks.
Leung TY, Chan LW, Tam WH, Leung TN, Lau TK
Gynecol Obstet Inves 2001;52(4): 227 - 231
319 The Development of a Midwife-based Obstetric Ultrasound Service in a Teaching Hospital.
Lau TK, Poon CF, Wong SM, Chau MMC,?Leung TY, Leung TN
HKJGOM 2001;2(2): 68 - 72
320 Whole blood mercury concentrations in sub-fertile men in Hong Kong.
Leung TY, Choy CMY, Yim SF, Lam CWK, Haines CJ
Aust NZ J Obstet Gyn 2001;41(1): 75 - 77
321 A survey of pregnant women's attitude towards breech delivery and external cephalic version.
Leung TY, Lau TK, Lo KWK, Rogers MS
Aust NZ J Obstet Gyn 2000;40(3): 253 - 259
322 Cell-free deoxyribonucleic acid in matrnal circulation as a marker of fetal-maternal heorrhage in patients undergoing external cephalic version near term.
Lau TK, Lo KWK, Chan LYS,?Leung TY, Lo DYM
Am J Obstet Gynecol 2000;183(3): 712 - 716
323 Effect of external cephalic version at term on fetal circulation.
Lau TK,?Leung TY, Lo KWK, Fok AWY, Rogers MS
Am J Obstet Gynecol 2000;182(5): 1239 - 1242
324 In Utero Treatment of Hydrops Fetalis due to Parvovirus B19 Infection: a Case Report.
Ng PS,?Leung TY, Leung TN, Lau TK
HKJGOM 2000;1(1): 67 - 70
325 Outcome of 555 Consecutive Transabdominal Chorionic Villus Samplings in a Teaching Hospital.
Lau TK, Chau MCM,?Leung TY, Pang MW, Fung TY, Leung TN
HKJGOM 2000;1(1): 21 - 27
326 Outcome of labour after successful external cephalic version at term complicated by isolated transient fetal bradycardia.
Lau TK, Lo KWK,?Leung TY, Fok AWY, Rogers MS
BJOG 2000;107(3): 401 - 405
327 Small bowel herniation through subumbilical port site following laparoscopic surgery at the time of reversal of anesthesia
Leung TY, Yuen PM
Gynecol Obstet Inves 2000;49(3): 209 - 210
328 Which Screening Test is the Best for Gestational Impaired glucose Tolerance and Gestational Diabetes Mellitus?
Tam WH, Rogers MS, Yip SK, Lau TK,?Leung TY
Diabetes Care 2000;23(9): 1432
329 Ectopic pregnancy diagnosed by laparoscopic ultrasound scan.
Leung TY, Ng PS, Fung TY
Ultrasound Obst Gyn 1999;13(4): 281 - 282
330 Hematuria and clot retention after Burch colposuspension and Cystofix Suprapubic Catheterization: Suprapublic Cystotomy as an Alternative Suprapubic Drainage Method.
Yip SK,?Leung TY, Chan CK
Int Urogynecol J 1998;9: 122 - 124
331 Vesicouterine Fistula: An Updated Revew.
Yip SK,?Leung TY
Int Urogynecol J 1998;9: 252 - 256
332 Misoprostol in the management of spontaneous abortion.
Chung TKH, Cheung LP,?Leung TY, Haines CJ, Chang AMZ
BJOG 1995;102(10): 832 - 835


O&G CUHK2019-10-09T12:32:04+08:00