The epidemiology of the human papillomavirus related to oropharyngeal head and neck cancer
Publication in refereed journal


香港中文大学研究人员 ( 现职)

陈英权教授 (耳鼻咽喉-头颈外科学系)

全文

数位物件识别号 (DOI) http://dx.doi.org/10.1002/lary.25767

引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/8WOS source URL
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/9Scopus source URL

其它资讯

摘要Objective To summarize the epidemiology of human papillomavirus (HPV)-related oropharyngeal squamous cell carcinomas (OSCC). Data Sources Articles in the English language referenced in MEDLINE/PubMed from the year 2000 onward. Review Methods Relevant articles pertaining to the epidemiology of HPV-related OSCC were selected for review, with a particular preference for articles from 200http://aims.cuhk.edu.hk/converis/portal/Publication/8 onward. Results The incidence of HPV-related OSCC continues to increase in North America and Western Europe, with up to 70% of new oropharyngeal cancer cases being attributed to HPV, whereas data from the developing world remain lacking. There is evidence to support distinct risk factors for HPV-related OSCC as compared with HPV-unrelated OSCC. The long-term natural history of HPV infections remains unknown. HPV-related OSCC are associated with an improved prognosis both at the time of primary diagnosis and disease progression. There is preliminary evidence to show that HPV vaccination initiatives are effective in preventing HPV cervical infections, although data related to oral HPV infections are lacking. Conclusion The epidemiology of HPV-related OSCC is evolving. Further efforts are needed to characterize the natural history of oral HPV infection and its relationship with the eventual development of HPV-associated OSCC to develop effective tools for secondary prevention.

着者Gooi Z., Chan J.Y.K., Fakhry C.
期刊名称LARYNGOSCOPE
出版年份2016
月份4
日期1
卷号126
期次4
出版社Lippincott Williams & Wilkins Ltd.
出版地United States
页次http://aims.cuhk.edu.hk/converis/portal/Publication/8http://aims.cuhk.edu.hk/converis/portal/Publication/94 - http://aims.cuhk.edu.hk/converis/portal/Publication/900
国际标準期刊号0023-http://aims.cuhk.edu.hk/converis/portal/Publication/852X
电子国际标準期刊号1531-4http://aims.cuhk.edu.hk/converis/portal/Publication/9http://aims.cuhk.edu.hk/converis/portal/Publication/95
语言英式英语

关键词epidemiology, head and neck cancer, human papillomavirus, Oropharynx, squamous cell carcinoma