Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 陈功教授 (外科学系) |
| 尹怀信教授 (耳鼻咽喉-头颈外科学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.2174/138945010791170897 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/2WOS source URL
其它资讯
摘要Current therapeutic options for patients with progressive thyroid cancer are relatively ineffective. There is a clear need to develop new alternatives for the management of this malignancy. As the knowledge of thyroid cancer biology advances, a large number of genetic events, molecular abnormalities, alterations of signaling pathways have been identified in the development and progression of thyroid neoplasms, and the potential exists to develop compounds targeted to treat thyroid cancers that do not respond to traditional therapy. In this review we described the recent development in thyroid carcinogenesis where the potential and novel intervention may exist. The discussion of thyroid carcinogenesis was integrated with exploitation of anti-thyroid agents that are currently either in clinical trials or in preclinical development for thyroid cancer.
着者Liu ZM, Wu TT, van Hasselt CA, Chen GG
期刊名称Current Drug Targets
出版年份http://aims.cuhk.edu.hk/converis/portal/Publication/2010
月份6
日期1
卷号11
期次6
出版社Bentham Science Publishers
页次716 - 73http://aims.cuhk.edu.hk/converis/portal/Publication/2
国际标準期刊号1389-4501
电子国际标準期刊号1873-559http://aims.cuhk.edu.hk/converis/portal/Publication/2
语言英式英语
关键词carcinogenesis; therapy; Thyroid cancer
Web of Science 学科类别Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY
