A benefit-risk assessment of ofloxacin otic solution in ear infection
Publication in refereed journal


香港中文大学研究人员 ( 现职)

唐志辉教授 (耳鼻咽喉-头颈外科学系)

全文

数位物件识别号 (DOI) http://dx.doi.org/10.2165/00002018-200326060-00003

引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/9WOS source URL

其它资讯

摘要Ofloxacin is a fluoroquinolone antibacterial with potent bactericidal activities and the topical otological preparation of this drug has been clinically utilised since the late 1http://aims.cuhk.edu.hk/converis/portal/Publication/980s. The rate of eradication with ofloxacin ranges from 83.3% to 100% for all pathogens commonly isolated from middle ear effusions in cases of otitis media and otitis externa. Despite the significant length of its usage, emergence of resistant pathogens has been rarely encountered in clinical trials; only two strains of Pseudomonas aeruginosa have been documented with decreased susceptibility to ofloxacin following the use of the otic solution.

着者Wai TKH, Tong MCF
期刊名称DRUG SAFETY
出版年份2003
月份1
日期1
卷号26
期次6
出版社ADIS INTERNATIONAL LTD
页次405 - 420
国际标準期刊号0114-5http://aims.cuhk.edu.hk/converis/portal/Publication/916
电子国际标準期刊号117http://aims.cuhk.edu.hk/converis/portal/Publication/9-1http://aims.cuhk.edu.hk/converis/portal/Publication/942
语言英式英语

Web of Science 学科类别Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY; Public, Environmental & Occupational Health; PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH, SCI; Toxicology; TOXICOLOGY