Publication in refereed journal
香港中文大学研究人员 ( 现职)
尹怀信教授 (耳鼻咽喉-头颈外科学系) |
全文
数位物件识别号 (DOI) http://dx.doi.org/10.1097/00005537-200305000-00013 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/9WOS source URL
其它资讯
摘要Objective: To investigate whether autologous ossicles can be safely used in ossicular reconstruction in cholesteatoma surgery after attempting cholesteatoma removal under the operating microscope. Study Design: A prospective fine-section histological study of formalin-stored ossicles, harvested from cholesteatomatous ears, to evaluate for existence of residual cholesteatoma after surface disease clearance under the operating microscope. Methods: One hundred four ossicles were harvested from 76 patients with cholesteatoma for the study. These malleus heads and incudes were categorized into three groups: group 1, ossicles with retained shape and useful bulk, treated by microscopic stripping alone; group 2, ossicles with retained shape and useful bulk, treated by microscopic stripping and drilling; and group 3, badly eroded ossicles, treated by microscopic stripping alone. These treated ossicles were then subjected to 4-mum histopathological study. Results: Residual disease was identified in 6 of the 104 ossicles. Residual disease was found only in badly eroded ossicles that are not suitable for reconstruction. All the usable ossicles were free of disease. Conclusions: Autologous ossicles that have retained body and bulk are safe to use for reconstruction after surface stripping under the operating microscope. Additional burring probably adds a further margin of safety.
着者Ng SK, Yip WWL, Suen M, Abdullah VJ, van Hasselt CA
期刊名称LARYNGOSCOPE
出版年份2003
月份5
日期1
卷号113
期次5
出版社LIPPINCOTT WILLIAMS & WILKINS
页次843 - 847
国际标準期刊号0023-852X
电子国际标準期刊号1531-4http://aims.cuhk.edu.hk/converis/portal/Publication/9http://aims.cuhk.edu.hk/converis/portal/Publication/95
语言英式英语
关键词autologous ossicles; cholesteatoma; ossiculoplasty
Web of Science 学科类别Medicine, Research & Experimental; MEDICINE, RESEARCH & EXPERIMENTAL; Otorhinolaryngology; OTORHINOLARYNGOLOGY; Research & Experimental Medicine