Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 尹怀信教授 (耳鼻咽喉-头颈外科学系) |
| 唐志辉教授 (耳鼻咽喉-头颈外科学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1007/BF00615121 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/26WOS source URL
其它资讯
摘要Photodynamic therapy (PDT) is a promising new modality in the treatment of cancer. In Hong Kong where nasopharyngeal carcinoma (NPC) is endemic, radiotherapy has been the primary treatment of choice. For recurrent disease after radiotherapy, there is no effective treatment, This latter report summarizes our initial experience in using PDT for these patients. Twelve patients (three females and nine males) with ages ranging from 33 to 65 years were treated with an infusion of hematoporphyrin derivative (5 mg/kg) 48-72 h before exposure to 200 J/cm(2) light (wavelength, 630 nm) delivered from a gold vapor laser. All 12 patients showed a dramatic response as judged by computed tomography or magnetic resonance imaging at 6 months post-PDT. Of the eight patients in whom cure was aimed for, three remained disease-free at 9-12 months after a single treatment. Three of the remaining four patients achieved useful palliation. Skin hypersensitivity occurred in two patients and was the only significant complication encountered. This experience indicates that PDT can be an encouraging palliative or definitive management for recurrent superficial NPC.
着者Tong MCF, vanHasselt CA, Woo JKS
期刊名称European Archives of Oto-Rhino-Laryngology
出版年份1996
月份3
日期1
卷号253
期次3
出版社SPRINGER VERLAG
页次189 - 192
国际标準期刊号0937-4477
电子国际标準期刊号1434-47http://aims.cuhk.edu.hk/converis/portal/Publication/26
语言英式英语
关键词management; nasopharyngeal carcinoma; photodynamic therapy; post-irradiation tumor recurrence
Web of Science 学科类别Otorhinolaryngology; OTORHINOLARYNGOLOGY
