Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 何咏珊小姐 (内科及药物治疗学系) |
| 吴兆文教授 (外科学系) |
| 马碧如教授 (肿瘤学系) |
| 陈德章教授 (肿瘤学系) |
| 欧志传先生 (肿瘤学系) |
| 陈明乐博士 (肿瘤学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1586/14789450.2013.858021 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/2WOS source URL
其它资讯
摘要Metastasis is the main cause of cancer death. As the tumor progresses, cells from the primary tumor site are shed into the bloodstream as circulating tumor cells (CTCs). Eventually, these cells colonize other organs and form distant metastases. It is therefore imperative that we gain a better understanding of the biological characteristics of CTCs for development of novel treatment modalities to minimize metastasis-associated cancer deaths. In recent years, rapid developments in technologies for the study of CTCs have taken place. We now have a variety of tools for the isolation and examination of CTCs which were not available before. This review introduces some commonly used protein markers in CTC investigations and summarizes a few advanced technologies which have been successfully applied for studying CTC biology at the protein level.
着者Chan CML, Au TCC, Chan ATC, Ma BBY, Tsui NBY, Ng SSM, Hui EP, Chan LWC, Ho WS, Yung BYM, Wong SCC
期刊名称EXPERT REVIEW OF PROTEOMICS
出版年份http://aims.cuhk.edu.hk/converis/portal/Publication/2013
月份1http://aims.cuhk.edu.hk/converis/portal/Publication/2
日期1
卷号10
期次6
出版社EXPERT REVIEWS
页次579 - 589
国际标準期刊号1478-9450
电子国际标準期刊号1744-8387
语言英式英语
关键词CellSearch; circulating tumor cells; CTC-chip; EPISPOT; immunomagnetic bead; proteomic
Web of Science 学科类别Biochemical Research Methods; BIOCHEMICAL RESEARCH METHODS; Biochemistry & Molecular Biology
