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Preclinical evaluation of combined TKI-258 and RAD001 in hepatocellular carcinoma (2013)_香港中文大学

香港中文大学 辅仁网/2017-06-28

Preclinical evaluation of combined TKI-25http://aims.cuhk.edu.hk/converis/portal/Publication/8 and RAD001 in hepatocellular carcinoma
Publication in refereed journal


香港中文大学研究人员 ( 现职)
许焕珍女士 (外科学系)
陈林教授 (肿瘤学系)
杨明明教授 (肿瘤学系)
陈德章教授 (肿瘤学系)
吕伟欣教授 (生物医学学院)
马碧如教授 (肿瘤学系)
许焕珍女士 (外科学系)
刘碧玉女士
黄智?博士 (肿瘤学系)


全文


引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/8WOS source URL

其它资讯

摘要RAD001 targets at the mammalian target of rapamycin (mTOR), while TKI-25http://aims.cuhk.edu.hk/converis/portal/Publication/8 is a potent tyrosine kinase inhibitor targeting at fibroblast growth factor receptor, vascular endothelial growth factor receptor, platelet-derived growth factor receptor and c-kit. We aim to study the activity of combined RAD001 and TKI-25http://aims.cuhk.edu.hk/converis/portal/Publication/8 in cell lines and xenograft model of hepatocellular carcinoma (HCC), with reference to the parallel and upstream pathways of Akt-mTOR axis.

着者Chan SL, Wong CH, Lau CPY, Zhou Q, Hui CWC, Lui VWY, Ma BBY, Chan ATC, Yeo W
期刊名称CANCER CHEMOTHERAPY AND PHARMACOLOGY
出版年份2013
月份6
日期1
卷号71
期次6
出版社SPRINGER
页次1417 - 1425
国际标準期刊号0344-5704
语言英式英语

关键词AKT; Hepatocellular carcinoma; mTOR; RAD001; TKI-25http://aims.cuhk.edu.hk/converis/portal/Publication/8
Web of Science 学科类别Oncology; ONCOLOGY; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

相关话题/肿瘤 外科 国际 生物医学 博士