Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 区皓智教授 (影像及介入放射学系) |
| 梁承晖教授 (肿瘤学系) |
| Professor Ann Dorothy KING (影像及介入放射学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1016/j.ejrex.2005.04.005 |
引用次数
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/4Scopus source URL
其它资讯
摘要Nasopharyngeal carcinoma (NPC) is highly sensitive to radiotherapy, however, the local tumour recurrence rate still is around 30% in those patients who present with advanced T stage disease [Wolden SL, Zelefsky MJ, Hunt MA, Rosenzweig KE, Chong LM, Kraus DH, Pfister DG, et al. Failure of a 3D conformal boost to improve radiotherapy for nasopharyngeal carcinoma. Int. J Radiat Oncol Biol Phys 2001;http://aims.cuhk.edu.hk/converis/portal/Publication/49:1229-3http://aims.cuhk.edu.hk/converis/portal/Publication/4]. Local tumour recurrence is particularly difficult to treat. Further radiotherapy causes significant acute and late complications, while surgery is only suitable for early stage recurrence and the role of chemotherapy is mainly palliative. The identification of recurrent nasopharyngeal carcinoma can be a challenge for both the clinician and the radiologist. The main diagnostic difficulty for MR imaging is the differentiation of recurrent tumour from post treatment scarring and fibrosis. However, we have encountered several other pathological processes that also may mimic local tumor recurrence. We present three such pathologies, radiation induced infection/inflammation, radiation induced granulation tissue, and radiation induced sarcoma (RIS). In all cases the patients underwent MR imaging for the evaluation of suspected tumor recurrence. Each case is presented, the pathology discussed, and the MR features that were useful in distinguishing these entities from malignancy are highlighted.
着者King A.D., Yuen E.H.Y., Po N.C., Sing F.L., Tse G.M.K., Kam M.K.M., Ahuja A.T.
期刊名称European Journal of Radiology Extra
出版年份2005
月份7
日期1
卷号55
期次1
出版社Elsevier BV
出版地Netherlands
页次23 - 27
国际标準期刊号1571-http://aims.cuhk.edu.hk/converis/portal/Publication/4675
语言英式英语
关键词Granulation tissue, Infection, Magnetic resonance (MR), Nasopharyngeal carcinoma, Radiation induced sarcoma, Tumour recurrence
