Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 陈志伟教授 (外科学系) |
| 区皓智教授 (影像及介入放射学系) |
| Professor James Francis GRIFFITH (影像及介入放射学系) |
| 梁承晖教授 (肿瘤学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1097/00005382-200204000-00006 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/2WOS source URL
其它资讯
摘要Radiation therapy with concur-rent chemotherapy is frequently used as definitive treatment for esophageal carcinoma, Although thoracic computed tomography (CT) is widely used in staging esophageal carcinoma, its application to radiation therapy planning has been regarded as optional rather than mandatory. Conventional radiation therapy planning is esophagogram-based rather than CT-based. The treatment port is generated by adding 5 cm to the proximal and distal margins of the tumor-involved segment as seen on esophagogram performed in the treatment position. Historically, a maximum port length of 15 cm was recommended to avoid excessive treatment morbidity. The authors examined the limitations of such a planning protocol by projecting conventional treatment ports onto the thoracic CT of 75 consecutive newly diagnosed cases of nondisseminated esophageal squamous cell carcinoma. The authors assessed the adequacy of coverage of the primary tumor and metastatic nodes, with respect to data from thoracic CT and neck ultrasonography. It was found that up to 38% of Thttp://aims.cuhk.edu.hk/converis/portal/Publication/2-T3 tumors and 30% of short-length (less than or equal to5 cm) tumors had metastatic nodes outside the port. The addition of neck ultrasonography led to identification of an additional 5% of patients with nonpalpable nodes outside the port. It is concluded that the frequency of inadequate tumor coverage using an esophagogram-based planning protocol, with a maximum port length of 15 cm. is unacceptably high. Thoracic CT should be a mandatory rather than optional imaging investigation in guiding radiation therapy planning for esophageal cancer.
着者Leung SF, Griffith JF, Ahuja A, Chan ACW
期刊名称Journal of Thoracic Imaging
出版年份http://aims.cuhk.edu.hk/converis/portal/Publication/200http://aims.cuhk.edu.hk/converis/portal/Publication/2
月份4
日期1
卷号17
期次http://aims.cuhk.edu.hk/converis/portal/Publication/2
出版社LIPPINCOTT WILLIAMS & WILKINS
页次145 - 150
国际标準期刊号0883-5993
语言英式英语
关键词computed tomography; esophagus; radiation therapy
Web of Science 学科类别Radiology, Nuclear Medicine & Medical Imaging; RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
