Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 尹怀信教授 (耳鼻咽喉-头颈外科学系) |
| 梁承晖教授 (肿瘤学系) |
| 杜家辉教授 (病理解剖及细胞学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1097/00005537-200108000-00023 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/13WOS source URL
其它资讯
摘要Objectives: To evaluate the potential use of con. tact endoscopy for the diagnosis of nasopharyngeal carcinoma (NPC). Study Design. Prospective study to examine the nasopharynx of 30 patients with nasopharyngeal carcinoma and 18 subjects with normal nasopharynx in a clinic setting using contact rhino-scopes (Karl Storz, Tuttlingen, Germany, 7215 AA, 0 degrees and 7215 BA, 30 degrees; 23 cm long, 4 mm. in diameter). Methods. The superficial cells of the normal nasopharynx and the nasopharyngeal tumors were stained with 1% methylene blue and examined with contact rhinoscopes at high magnifications (x60 and x150). The areas under examination were then biopsied. The contact endoscopic images were compared with the corresponding hematoxylin and eosin-stained histologic sections of the biopsied tissues. Results: Sixty-six procedures were performed in 48 patients. The images of normal pseudostratified ciliated epithelium and squamous epithelium were readily recognized by contact endoscopy in all subjects with normal nasopharynx (10 men and 8 women; mean age, 51.9 y). Twenty-six of 30 patients with NPC (86.6%;, 18 men and 8 women; mean age, 50.6 y) were successfully examined by contact endoscopy under local anesthesia. In these 26 patients, two patterns of malignant cells were identified with contact endoscopy. The patterns of contact endoscopic images corresponded well with the histologic findings. Conclusion: Contact endoscopy is an accurate and reliable office-based procedure, which allows for in-vivo diagnosis of nasopharyngeal carcinoma.
着者Pak MW, To KF, Leung SF, van Hasselt CA
期刊名称LARYNGOSCOPE
出版年份2001
月份8
日期1
卷号111
期次8
出版社LIPPINCOTT WILLIAMS & WILKINS
页次1453 - 1458
国际标準期刊号0023-852X
电子国际标準期刊号1531-4995
语言英式英语
关键词contact endoscope; in-situ histology; nasopharyngeal carcinoma; nasopharynx
Web of Science 学科类别Medicine, Research & Experimental; MEDICINE, RESEARCH & EXPERIMENTAL; Otorhinolaryngology; OTORHINOLARYNGOLOGY; Research & Experimental Medicine
