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Proteome analysis and its impact on the discovery of serological tumor markers (2001)_香港中文大学

香港中文大学 辅仁网/2017-06-27

Proteome analysis and its impact on the discovery of serological tumor markers
Publication in refereed journal


香港中文大学研究人员 ( 现职)
庄立信教授 (肿瘤学系)
潘全威教授 (儿科学系)


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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/55WOS source URL

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摘要Background: Proteomics is a rapidly growing field of research that is becoming increasingly important as we enter the post-genome era. Remarkable improvements in the technologies of high-resolution two-dimensional polyacrylamide gel electrophoresis (2D PAGE) and mass spectrometry (MS) have marked the start of proteome analysis and its application to the study of human diseases. Besides studying the proteins involved in carcinogenesis, it is also applicable to the discovery of serological tumor markers for clinical uses, such as for hepatocellular carcinoma. Conclusions: The combination of 2D PAGE and MS is the most widely used technique for proteomics, although other more automated high-throughput techniques are being developed. (C) 2001 Elsevier Science B.V. All rights reserved.

着者Poon TCW, Johnson PJ
会议名称Chinese Congress of Clinical Chemistry and Laboratory Medicine
会议开始日11.06.2000
会议完结日15.06.2000
会议地点HONG KONG
期刊名称Clinica Chimica Acta
出版年份2001
月份11
日期1
卷号313
期次1-2
出版社ELSEVIER SCIENCE BV
页次231 - 239
国际标準期刊号0009-8981
电子国际标準期刊号1873-3492
语言英式英语

关键词hepatocellular carcinoma; malignancy; proteome; proteomics; serum; tumor markers
Web of Science 学科类别Medical Laboratory Technology; MEDICAL LABORATORY TECHNOLOGY

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