Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 李伟业教授 (药剂学院) |
| 周喜林教授 (药剂学院) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.2174/13816128113199990396 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/9WOS source URL
其它资讯
摘要Solid state manipulation by amorphous solid dispersion has been the subject of intensive research for decades due to their excellent potential for dissolution and bioavailability enhancement. The present review aims to highlight the latest advancement in this area, with focus on the fundamentals, characterization, formulation development and manufacturing of amorphous solid dispersions as well as the new generation amorphization technologies. Additionally, specific applications of amorphous solid dispersion in the formulation of herbal drugs or bioactive natural products are reviewed to reflect the growing interest in this relatively neglected area.
着者Lee TWY, Boersen NA, Hui HW, Chow SF, Wan KY, Chow AHL
期刊名称Current Pharmaceutical Design
出版年份2014
月份1
日期1
卷号20
期次3
出版社Bentham Science Publishers
页次303 - 324
国际标準期刊号1381-6128
电子国际标準期刊号1873-4286
语言英式英语
关键词amorphization technologies; Amorphous solid dispersion; glass transition; molecular mobility; physical stability; polymer carrier
Web of Science 学科类别Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY
