Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 周喜林教授 (药剂学院) |
| 何淑珊博士 (药剂学院) |
| 朱家荣教授 (药剂学院) |
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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/56WOS source URL
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摘要Coriolus versicolor (CV) is a medicinal mushroom widely prescribed for the prophylaxis and treatment of cancer and infection in China. In recent years, it has been extensively demonstrated both preclinically and clinically that aqueous extracts obtained from CV display a wide array of biological activities, including stimulatory effects on different immune cells and inhibition of cancer growth. The growing popularity of aqueous CV extracts as an adjunct medical modality to conventional cancer therapies has generated substantial commercial interest in developing these extracts into consistent and efficacious oral proprietary products. While very limited information is available on the physical, chemical, and pharmacodynamic properties of the active principles present in these extracts, there has been sufficient scientific evidence to support the feasibility of developing at least some of these constituents into an evidence-based immunodulatary agent. In this article, the background, traditional usage, pharmacological activities, clinical effects, adverse reactions, active constituents, and regulatory aspects of CV are reviewed. Presented also in this review are the current uses and administration, potential drug interactions, and contraindication of aqueous extracts prepared from CV. (C) 2002 the American College of Clinical Pharmacology.
着者Chu KKW, Ho SSS, Chow AHL
期刊名称Journal of Clinical Pharmacology
出版年份2002
月份9
日期1
卷号42
期次9
出版社SAGE PUBLICATIONS INC
页次976 - 984
国际标準期刊号0091-2700
电子国际标準期刊号1552-4604
语言英式英语
Web of Science 学科类别Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY
