Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 蔡继洲博士 (那打素护理学院) |
| 薛咏红教授 (那打素护理学院) |
| 黄美玲教授 (那打素护理学院) |
| 许世全教授 (体育运动科学系) |
| 郑可瑜教授 (那打素护理学院) |
| 陈惠娇教授 (那打素护理学院) |
| 车锡英教授 (那打素护理学院) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/https://doi.org/10.1016/S0140-6736(16)31991-2 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/0WOS source URL
其它资讯
摘要Background Despite well-established benefits of exercise in the management of metabolic syndrome, evidence
to support exercise adherence after program completion is lacking. We used a smartphone-based exercise adherence
intervention (Virtual Trainer; Ex-VT) for adults with metabolic syndrome in Hong Kong, China. The objectives were
to measure the feasibility, potential effectiveness, and implementation of Ex-VT in sustaining prescribed exercise
practice for risk reduction in metabolic syndrome.
Methods In this multisite, randomised controlled trial, participants with metabolic syndrome were randomly allocated
to either intervention (Ex-VT) or exercise reference (control) groups using block randomisation with a block size
of ten. Both groups attended four once-weekly group exercise sessions. The Ex-VT group received goal-directed,
person-centered exercise adherence coaching via a smartphone virtual trainer application. Data was collected at
baseline and at 12 weeks. Primary outcome was adherence to exercise prescription, as measured using pedometers
and International Physical Activity Questionnaire. Changes in metabolic syndrome risk indicators (waist
circumference, blood pressure, and blood lipid and glucose concentrations) were also measured after a 12 h fast. Data
analysis was based on intention to treat. The trial is registered with Chinese University of Hong Kong Centre for
Clinical Research and Biostatistics, number CUHK_TMPhttp://aims.cuhk.edu.hk/converis/portal/Publication/0http://aims.cuhk.edu.hk/converis/portal/Publication/0http://aims.cuhk.edu.hk/converis/portal/Publication/056. Ethics approval was obtained from the Joint Chinese
University of Hong Kong–New Territories East Clinical Research Ethics Committee and written consent were
obtained from participants.
Findings Twenty subjects were recruited to the study (recruitment rate: 71·4%), and randomly assigned, 1:1, to Ex-VT
or control groups. They were aged 3http://aims.cuhk.edu.hk/converis/portal/Publication/0–69 (mean 56·85 [SD 7·http://aims.cuhk.edu.hk/converis/portal/Publication/08]), 65% women, and 55% worked full-time. Two subjects
(one per group) dropped out (retention rate: 9http://aims.cuhk.edu.hk/converis/portal/Publication/0% for both groups). At 12 weeks, participants in the Ex-VT group
demonstrated better adherence with exercise prescription (72%) than those in the control group (48%; p=http://aims.cuhk.edu.hk/converis/portal/Publication/0·http://aims.cuhk.edu.hk/converis/portal/Publication/036).
Reductions from baseline in systolic blood pressure (p=http://aims.cuhk.edu.hk/converis/portal/Publication/0·http://aims.cuhk.edu.hk/converis/portal/Publication/02), diastolic blood pressure (p=http://aims.cuhk.edu.hk/converis/portal/Publication/0·http://aims.cuhk.edu.hk/converis/portal/Publication/045), and waist
circumference (p=http://aims.cuhk.edu.hk/converis/portal/Publication/0·http://aims.cuhk.edu.hk/converis/portal/Publication/048) were seen in the Ex-VT group, despite no between-group difference. We found no significant
changes in blood lipid and glucose concentrations. No adverse events were reported.
Interpretation High retention rates suggest that Ex-VT is an acceptable intervention for this population. Preliminary
findings on adherence and metabolic syndrome risk indicators suggest that a large randomised controlled trial
to explore the effects of Ex-VT would be safe, feasible, and warranted.
着者Sit JWH, Chair SY, Hui SSC, Choi KC, Chan AWK, Wong EML, Cheng HY
期刊名称Lancet
出版作品名称LANCET
出版年份2http://aims.cuhk.edu.hk/converis/portal/Publication/016
月份1http://aims.cuhk.edu.hk/converis/portal/Publication/0
日期3http://aims.cuhk.edu.hk/converis/portal/Publication/0
卷号388
期次Supplement 1
出版社Elsevier: Lancet
页次64 - 64
国际标準期刊号http://aims.cuhk.edu.hk/converis/portal/Publication/014http://aims.cuhk.edu.hk/converis/portal/Publication/0-6736
电子国际标準期刊号1474-547X
语言英式英语
Web of Science 学科类别Medicine, General & Internal;General & Internal Medicine
