Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 苏帼慧教授 (那打素护理学院) |
| 黄祖莉教授 (那打素护理学院) |
| 邓颖琪博士 (那打素护理学院) |
| 罗文轩博士 (那打素护理学院) |
| 徐国荣教授 (生物医学学院) |
| 陈叶咏娴教授 (那打素护理学院) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.3390/ijms17030286 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/2WOS source URL
其它资讯
摘要Lung cancer is ranked first worldwide as one of the main cancers in terms of prevalence and mortality rate. The development of effective treatment strategies against lung cancer is therefore of paramount importance. Traditionally, chemotherapy was employed in the treatment of various cancers. However, the non-specific nature of the actions of chemotherapeutic drugs and the potential for tumors to develop resistance to these drugs may render chemotherapy a less favorable option for cancer treatment. Immunotherapy provides an alternative strategy for this purpose. It involves the utilization of the immune system and the immune effector cells to elicit an immune response to the tumors, thereby eliminating them. Strategies include the administration of pro-inflammatory cytokines for immune stimulation, the removal of immunological checkpoints using monoclonal antibodies, and the use of cancer vaccines to enhance immunity against tumors. This article summarizes the above strategies, highlights the reasons why immunotherapy is superior to chemotherapy for the purpose of tumor removal, and reviews the recent clinical studies comparing the clinical outcomes of patients undergoing immunotherapy and chemotherapy. The article also describes advances in immunotherapeutic strategies for the treatment of lung cancer.
着者Chan CWH, Tsui SKW, Law BMH, So WKW, Tang FWK, Wong CL
期刊名称International Journal of Molecular Sciences
出版年份http://aims.cuhk.edu.hk/converis/portal/Publication/2016
月份3
日期1
卷号17
期次3
出版社MDPI AG
国际标準期刊号1661-6596
语言英式英语
关键词chemotherapy; immune system; immunotherapy; lung cancer
Web of Science 学科类别Biochemistry & Molecular Biology; Chemistry; Chemistry, Multidisciplinary
