Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 宋银子教授 (医学院) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1097/00006454-199809001-00014 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/14WOS source URL
其它资讯
摘要A 5-year territory-wide retrospective survey of invasive Haemophilus influenzae type b (Hib) diseases in Hong Kong established that the annual incidence for children <5 years old was 2.7 per 100 000 [95% confidence interval (CI), 2.0 to 3.5]. However, the corresponding annual incidence in Vietnamese refugees in Hong Kong was 42.7 per 100 000 (95% CI 17.2 to 87.9), giving a relative risk of 18.5 (95% CI 8.3 to 41.0). The nasopharyngeal carriage rate of Hib was zero in 621 healthy Chinese children and 1.3% (95% CI 0.04 to 2.63%) in 300 healthy Vietnamese refugees 2 months to 5 years old in Hong Kong. The corresponding carriage rate of nontypable H. influenzae was 5.8% (95% CI 1.4 to 7.6%) in Chinese and 65.4% (95% CI 58.9 to 69.8) in Vietnamese. In a larger study of 1812 healthy Chinese children between 6 months and 5 years of age investigated by throat swabs, again no Hib was isolated but http://aims.cuhk.edu.hk/converis/portal/Publication/141 children (7.8%) were found to be carriers of non-type b H. influenzae. In a study of 596 healthy Chinese children and adults, 25% had the protective level of anti-Hib antibody of >0.15 mu g/ml by 1 year and 90% had reached >0.15 mu g/ml by 6 years of age. There was some evidence that these "natural" antibodies against Hib in Hong Kong Chinese were cross-reacting antibodies against antigens on other encapsulated bacteria.
着者Lau YL, Yung R, Low L, Sung R, Leung CW, Lee WH
会议名称1st International Conference on Haemophilus Influenzae Type b Infection in Asia
会议开始日17.12.1996
会议完结日19.12.1996
会议地点BALI
期刊名称PEDIATRIC INFECTIOUS DISEASE JOURNAL
出版年份1998
月份9
日期1
卷号17
期次9
出版社LIPPINCOTT WILLIAMS & WILKINS
页次S165 - S169
国际标準期刊号0891-3668
语言英式英语
关键词Haemophilus influenzae; Haemophilus influenzae type b; Hong Kong; meningitis
Web of Science 学科类别Immunology; IMMUNOLOGY; Infectious Diseases; INFECTIOUS DISEASES; Pediatrics; PEDIATRICS
