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Evaluation of impedance based indices of cardiac contractility in dogs (2004)_香港中文大学麻醉及深切治療學系 (ANS)

香港中文大学 辅仁网/2017-06-20

Evaluation of impedance based indices of cardiac contractility in dogs
Publication in refereed journal


香港中文大学研究人员 ( 现职)
郭志德教授 (麻醉及深切治疗学系)


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Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/5Scopus source URL

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摘要Objective. Cardiac function can be monitored simply and safely by the impedance method. A number of parameters that reflect cardiac contractility can be derived from the impedance waveform. These include the systolic time ratio (STR), the index of contracticity (IC), the acceleration index (ACI) and the Heather index. This study evaluates their reliability. Methods. In sixteen anaesthetized dogs an - ultrasonic flow probe was placed on the ascending aorta using a left thoracotomy approach and catheter placed in the femoral artery to measure blood pressure. This allowed the reference measurement of cardiac contractility from blood flow (dF/dt(max)) and pressure (dP/dt(max)). Comparative 1-minute impedance based measurements were made by a RheoCardioMonitor (ACMA, Singapore), whilst contractility was increased 2 to 6 fold, over 113 (http://aims.cuhk.edu.hk/converis/portal/Publication/52 to 212) minutes, using dopamine and adrenaline infusions. The association between the reference and impedance measurements was determined by correlation. The correlation coefficients (r) were compared using paired t-tests. Results are presented as mean ± SD. Results. The ACI (r = 0.76 ± 0.13) and Heather index (r = 0.74 ± 0.14) were more closely associated with the reference measurement (dF/dt(max)) than IC (r = 0.6http://aims.cuhk.edu.hk/converis/portal/Publication/5 ± 0.23) (p < 0.0http://aims.cuhk.edu.hk/converis/portal/Publication/5) and STR (r = 0.33 ± 24) (p < 0.01). Results for ACI and the Heather index were similar. STR was unrelated to the reference method in 10 out of 16 experiments. Correlation was better when using flow probe data (dF/dt(max)) than arterial pressure data (dP/dt(max)) (p < 0.0http://aims.cuhk.edu.hk/converis/portal/Publication/5). Conclusions. ACI and the Heather index were the most reliable impedance derived indices of cardiac contractility. ? 2004 Kluwer Academic Publishers.

着者Peng Z.-Y., Critchley L.A.H., Fok B.S.P., James A.E.
期刊名称Journal of Clinical Monitoring and Computing
出版年份2004
月份4
日期1
卷号18
期次2
出版社Kluwer Academic Publishers
出版地Netherlands
页次103 - 109
国际标準期刊号1387-1307
电子国际标準期刊号1http://aims.cuhk.edu.hk/converis/portal/Publication/573-2614
语言英式英语

关键词Aorta, Canine, Contractility, Flow probe, Impedance cardiography

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