教授，博士生导师
E-mail: songgs@hnu.edu.cn; songguosheng12@sina.com










基本信息


宋国胜，依托化学生物传感与计量学国家重点实验室，从事纳米探针及活体成像分析的研究工作。
课题组主页：https://www.x-mol.com/groups/zhang_xiaobing/people
教育背景
2014年博士毕业于东华大学；随后在苏州大学（导师：刘庄教授） 和美国斯坦福大学-医学院（分子影像中心）（导师：Jianghong Rao教授）从事博士后研究。2018年入职湖南大学。


工作履历
研究领域
生命分析化学
活体分子影像：光声成像、长余辉成像、化学发光成像、核磁成像
癌症的早期诊断、治疗及疗效检测


科研项目
1. 主持的项目：国家自然科学基金-青年基金； 国家自然科学基金-面上项目


2. 作为科研骨干参与：国家重点研发计划“纳米科技”重点专项
学术成果
代表性论文：


Shi L.; Song, G.* et al; An Acidity‐Unlocked Nanoplatform Enables Self‐Boosting ROS Generation through Upregulation of Lactate for Highly Specific Chemodynamic Therapy, Angew. Chem. Int. Ed. 2021 https://doi.org/10.1002/anie. (IF = 12)

Chen, F.; Song, G.* et al; Activatable Magnetic/Photoacoustic Nanoplatform for Redox-Unlocked Deep-Tissue Molecular Imaging In Vivo via Prussian Blue Nanoprobe. Analytical chemistry 2020, 92 (19), 13452-13461. (IF =6)
Zhang, C. Song, G.*; et al, H 2 S-Activated “One-Key Triple-Lock” Bis-Metal Coordination Network for Visualizing Precise Therapy of Colon Cancer. CCS Chemistry 2020, 2126-2142.
Lu, C. Song, G.* et al, Light-free Generation of Singlet Oxygen through Manganese-Thiophene Nanosystems for pH-Responsive Chemiluminescence Imaging and Tumor Therapy. Chem 2020, 6 (9), 2314-2334. (IF = 19)
Song, G*.; Rao, J.* et al. FeCo nanoparticles as ultrasensitive magnetic-particle-imaging tracers with photothermal and magnetothermal properties. Nature Biomedical Engineering 2020,4, 325. (IF = 18)
Yuan, H.; Song, G* et al. Copper-Thioguanine Metallodrug with Self-reinforcing Circular Catalysis for Activatable MRI Imaging and Amplifying Specificity of Cancer Therapy, SCIENCE CHINA Chem. 2020. (IF = 6)
Wang, B.; Song, G* et al. Oxygen-Embedded Pentacene Based Near-Infrared Chemiluminescent Nanoprobe for Highly Selective and Sensitive Visualization of Peroxynitrite In Vivo, Anal. Chem. 2020, 92: 4154.(IF = 6)
Wang, Y.; Song, G.* et al. Reactive Oxygen Correlated Chemiluminescent Imaging of Semiconducting Polymer Nanoplatform for Monitoring Chemodynamic Therapy. Nano Lett. 2020, 9, 6371. (IF = 12)
Wang P.; Song G.*; Zhang X.* et al. In Vivo Monitoring Therapeutic Response by Self-Reporting Upconverting Covalent Organic Framework Nanoplatform, Chem Sci. 2020, DOI 10.1039/C9SC04875H (IF = 9.5)
Teng, L. ^?; Song, G. ^?; Zhang, X.-B.* et al. Nitric Oxide-Activated "Dual-Key-One-Lock" Nanoprobe for in Vivo Molecular Imaging and High-Specificity Cancer Therapy. J. Am. Chem. Soc. 2019, 141, 13572. (IF = 14)
Yin, B.; Song, G.*; et. al. Oxygen-embedded Quinoidal Acene Based Semiconducting Chromophore Nanoprobe for Amplified Photoacoustic Imaging and Photothermal Therapy. Anal. Chem. 2019, DOI: 10.1021/acs.analchem.9b04429. (IF = 6)
Zhang, C.; Yin, X.*; Song, G.* et al. Two-Photon Supramolecular Nanoplatform for Ratiometric Bioimaging. Anal. Chem. 2019, 91, 6371. (IF = 6)
Yin, S.; Song, G.*; Yin, X.*; Zhang, X.*, et al. Persistent Regulation of Tumor Microenvironment via Circulating Catalysis of MnFe2O4@Metal-Organic Frameworks for Enhanced Photodynamic Therapy. Adv. Funct. Mater. 2019, 29, **. (IF = 15)
Song, G.; Rao, J.* et al., A Magneto-Optical Nanoplatform for Multimodality Imaging of Tumors in Mice. ACS Nano 2019, 13, 7750. (IF = 14)
Song, G.; Rao, J.* et al Janus Iron Oxides @ Semiconducting Polymer Nanoparticle Tracer for Cell Tracking by Magnetic Particle Imaging. Nano Lett. 2018, 18, 182. (IF = 12)


Before 2018

1. Chen, Y.; Song, G.*; Liu, Z.*, et al. Drug-Loaded Mesoporous Tantalum Oxide Nanoparticles for Enhanced Synergetic Chemoradiotherapy with Reduced Systemic Toxicity. Small 2017, 13 (8). (IF = 10)
2. Li, C.;Li, W.*; Song, G.*; Shen, J.*, et. al. Combined bortezomib-based chemotherapy and p53 gene therapy using hollow mesoporous silica nanospheres for p53 mutant non-small cell lung cancer treatment. Biomater. Sci. 2017, 5, 77. (IF = 5)
3. Song, G. ^?; Ji, C. ^?; Liu, Z.* el al. TaOx decorated perfluorocarbon nanodroplets as oxygen reservoirs to overcome tumor hypoxia and enhance cancer radiotherapy. Biomaterials 2017, 112, 257. (IF = 10)
6. Song, G.; Liu, Z.* et al. Emerging Nanotechnology and Advanced Materials for Cancer Radiation Therapy. Adv. Mater. 2017, 29 (32). (IF = 25)
5. Song, G.; Hu, J.*; Liu, Z.*, et al. Degradable Molybdenum Oxide Nanosheets with Rapid Clearance and Efficient Tumor Homing Capabilities as a Therapeutic Nanoplatform. Angew. Chem. Int. Ed.2016, 55, 2122. (IF = 12)
6. Song, G.; Liu, Z.* et al. Perfluorocarbon-Loaded Hollow Bi2Se3 Nanoparticles for Timely Supply of Oxygen under Near-Infrared Light to Enhance the Radiotherapy of Cancer. Adv. Mater. 2016, 28, 2716. (IF = 25)
7. Song, G.; Liu, Z.* et al Catalase-Loaded TaOx Nanoshells as Bio-Nanoreactors Combining High-Z Element and Enzyme Delivery for Enhancing Radiotherapy. Adv. Mater. 2016, 28, 7143. (IF = 25)
8. Song, G.; Liu, Z.*, et al. All-in-One Theranostic Nanoplatform Based on Hollow TaOx for Chelator-Free Labeling Imaging, Drug Delivery, and Synergistically Enhanced Radiotherapy. Adv. Funct. Mater. 2016, 26, 8243. (IF = 15)
9. Song, G.; Yang, K.*; Liu, Z.*, et al. Core-Shell MnSe@Bi2Se3 Fabricated via a Cation Exchange Method as Novel Nanotheranostics for Multimodal Imaging and Synergistic Thermoradiotherapy. Adv. Mater. 2015, 27, 6110. (IF = 25)
10. Song, G.; Hu J* et al. A Low-Toxic Multifunctional Nanoplatform Based on Cu9S5@mSiO2Core-Shell Nanocomposites: Combining Photothermal- and Chemotherapies with Infrared Thermal Imaging for Cancer Treatment. Advanced Adv. Funct. Mater. 2013, 23,4281(IF = 15)


奖励与荣誉
“****奖励计划”- 青年项目

湖南省“芙蓉****”****
湖南省“湖湘青年英才”支持计划上海市优秀博士学位论文