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基本情况：姓名贺治国
出生年月 1978-06职称教授
学历 研究生学位博士
籍贯江西莲花党派中共党员
电话**传真
邮箱zghe@csu.edu.cnQQ**
个人简历
学习工作访学经历
年份
中南大学资源加工与生物工程学院矿物加工工程专业本科
1996.9-2000.7
中南大学资源加工与生物工程学院矿物加工工程专业硕士
2000.9-2002.7
中南大学资源加工与生物工程学院微生物专业博士（提前攻博）
2002.9-2005.6
中南大学资源加工与生物工程学院讲师
2005.6-2006.9
中南大学资源加工与生物工程学院副教授
2006.10-2014.9
加拿大University of Calgary 博士后
2008.3-2010.12
中南大学资源加工与生物工程学院教授、博士生导师
2014年10月-至今
研究方向
矿产资源综合利用及生物冶金
微生物宏基因组学
环境微生物技术
矿冶废水的处理技术及尾矿资源的开发利用
教学方面
主讲本科生 《基因工程》、《生物技术概论》 课程
主讲研究生 《微生物分子生态学》课程
承担课题
基于DNA-稳定同位素探针对腾冲酸性温泉甲烷氧化菌群的宏基因组学研究，国家自然科学基金（No.**）,2014-2017,项目负责人
选矿废水的高效生物处理技术及工艺，教育部“新世纪优秀人才支持计划”， 2013-2015，项目负责人
难处理金矿生物预氧化技术及工艺，2011-2015，中南大学升华“育英计划”青年创新人才资助计划，项目负责人
金属硫化矿浸出专属性微生物多样性与复杂界面作用，国家自然科学基金（No. **）,2014-2017,项目负责人
主要论文(#:标识为通讯作者; IF为SCI期刊影响因子)
Shuzheng Li, Hui Zhong,Zhiguo He#.Microbial community shifts during the process of marmatite bioleaching.Hydrometallurgy. **:127-131.（IF: 2.2)
Shuzheng Li, Hui Zhong,Zhiguo He#. Bioleaching of a low-grade nickel-copper sulfide by mixture of four thermophiles.Bioresource technology.2014, 153:300-6.（IF: 5.04)Zhiguo He,Shuzhen Li,Lisha Wang,Hui ZhongCharacterization of Five Chromium-Removing Bacteria Isolated from Chromium-Contaminated Soil.Water, Air, & Soil Pollution.2014,225: 1904.（IF: 1.7)
Zhiguo He,Yanping Yang,Shan Zhou, Yuehua Hu, Hui Zhong. Effect of pyrite, elemental sulfur and ferrous ions on EPS production by metal sulfide bioleaching microbes.Trans.Nonferrous Met.Soc.China.2014, 24(4):1171-1178.
Ivica Tamas, Angela V Smirnova,Zhiguo He, Peter F Dunfield. The (d)evolution of methanotrophy in the 3 Beijerinckiaceae-a comparative genomics analysis.ISME Journal. 2014, 8(2):369-82. (Nature出版集团旗下期刊，环境领域顶级期刊，IF: 9.27)
Dongshan An,Sean M. Caffrey,Jung Soh,Akhil Agrawal,Damon Brown,Karen Budwill,Xiaoli Dong,Peter F. Dunfield,Julia Foght,Lisa M. Gieg,Steven J. Hallam,Niels W. Hanson,Zhiguo He,Thomas R. Jack,Jonathan Klassen,Kishori M. Konwar,Eugene Kuatsjah,Carmen Li,Steve Larter,Verlyn Leopatra,Camilla L. Nesb,Thomas Oldenburg,Antoine P. Pagé,Esther Ramos-Padron,Fauziah F. Rochman,Alireeza Saidi-Mehrabad,Christoph W. Sensen,Payal Sipahimalani,Young C. Song,Sandra Wilson,Gregor Wolbring,Man-Ling Wong, andGerrit Voordouw. Metagenomics of hydrocarbon resource environments indicates aerobic taxa and genes to be unexpectedly common.Environmental Science & Technology.2013, 47 (18): 10708–10717 (环境领域顶级期刊，影响因子IF=5.48).
Alireza Saidi-Mehrabad*,Zhiguo He*, Ivica Tamas, Christine E Sharp, Allyson L Brady, Fauziah F Rochman, Levente Bodrossy, Guy CJ Abell, Tara Penner, Xiaoli Dong, Christoph W Sensen and Peter F Dunfield.5 Methanotrophic bacteria in oilsands tailings ponds of northern Alberta.ISME Journal. 2013（7）：908-921. *:共同第一作者。(Nature出版集团旗下期刊，环境领域顶级期刊，IF: 9.27)
He Zhiguo, Yang Yanping, Zhou Shan, Zhong Hui, Sun Wei. The effect of culture condition and ionic strength on proton adsorption at the surface of the extreme thermophileAcidianus manzaensis.Colloids and Surfaces B: Biointerfaces.2013, 102: 667-73. ( IF: 4.28 )
He Zhiguo, Yin Zhen, Wang Xin, Zhong Hui, Sun Wei. Microbial community changes during the process of pyrite bioleaching.Hydrometallurgy2012,125–126: 81–89 ( IF: 2.2 )
He Zhiguo,Zhao Jianchun, Hu Yuehua, Qiu Guanzhou. Effect of L-cysteine on the bioleaching of Ni-Cu sulphide byA.manzaensis.J. Cent. Sou. Univ. T.2011, 18(2): 381-385. ( IF: 0.25 )
He Zhiguo, Gao Fengling, Zhao Jianchun, Hu Yuehua, Qiu Guanzhou. Insights into the dynamics of bacterial communities during chalcopyrite bioleaching.FEMS Microbiol. Ecol.2010, 74: 155-164. ( IF: 3.60 )
He Zhiguo, Zhao Jiancun, Gao Fengling, Hu Yuehua, Qiu Guanzhou. Monitoring bacterial community shifts in bioleaching of Ni-Cu sulfide.Bioresour. Technol.2010, 8287-8293 ( IF: 5.04 )
He Zhiguo, De Buck Jeroen. Localization of proteins in the cell wall ofMycobacterium aviumsubsp.paratuberculosisK10 by proteomic analysis.Proteome Sci.2010, 8:21. ( IF: 2.56 )
He Zhiguo, De Buck Jeroen. Cell wall proteome analysis ofMycobacterium smegmatisstrain MC2 155.BMC Microbiol.2010, 10:121. ( IF: 2.88 )
He Zhiguo, Gao Fengling, Zhong Hui, Hu Yuehua. Effects of L-cysteine on Ni–Cu sulfide and marmatite bioleaching byAcidithiobacillus caldus.Bioresour. Technol.2009, 100(3): 1383-1387. ( IF: 5.04 )
He Zhiguo, Gao Fengling, Sha Tao, Hu Yuehua, He Chao. Isolation and characterization of a Cr(VI)-reduction Ochrobactrum sp. strain CSCr-3 from chromium landfill.J. Hazard. Mater.2009, 163: 869-873. ( IF: 4.33 )
Xiao Shengmu, Xie Xuehui, Liu Jianshe,He Zhiguo*, Hu Yuehua. Compositions and structures of archaeal communities in acid mineral bioleaching systems of dongxiang copper mine and yinshan lead–zinc mine.Curr. Microbiol.2008, 57(3):239-44. *corresponding author ( IF: 1.33 )
He Zhiguo, Xiao Shengmu, Xie Xuehui, Hu Yuehua. Microbial diversity in acid mineral bioleaching systems of dongxiang copper mine and Yinshan lead-zinc mine. Extremophiles 2008, 12(2):225-34. ( IF: 2.94 )
Zhong Hui,He Zhiguo, Li Xiaoling, Li Guiyuan. Studies on polyamidoamine dendrimers as efficient gene delivery vector.J. Biomater. Appl.2008, 22 (6): 527-544. ( IF: 1.64 )
He Zhiguo, Zhong Hui, Hu Yuehua, Li Guiyuan. Research on the proteome response ofAcidithiobacillus ferrooxidansto phosphate starvation by SELDI-Protein Chip technologies.Prog. Biochem. Biophys.2008, 35(1):1~8. ( IF: 0.21)
He Zhiguo,Xiao Shengmu, Xie Xuehui, Zhong Hui, Hu Yuehua, Li Qinghua, Gao Fengling, Li Guiyuan, Liu Jianshe, Qiu Guanzhou.Molecular diversity of microbial community in acid mine drainages of yunfu sulfide Mine.Extremophiles2007, 11(2): 305-14. ( IF: 2.94 )
He Zhiguo, Xie Xuehui, Xiao Shengmu, Liu Jianshe, Qiu Guanzhou. Microbial diversity of mine water at Zhong Tiaoshan copper mine,China.J. Basic Microb.2007, 47, 485~495. ( IF: 1.1 )
He Zhiguo, Xie Xuehui, Xiao Shengmu, Liu Jianshe. Microbial populations in acid mineral bioleaching systems of Tong Shankou Copper Mine,China.J. Appl. Microbiol.2007, 103: 1227-1238. ( IF: 2.5 )
He Zhiguo, Zhong Hui, Hu Yuehua, Xiao Shengmu, Xu Jing. Analysis of differential protein expression inAcidithiobacillus ferrooxidansgrown under different energy resources respectively using SELDI-ProteinChip technologies.J. Microbiol. Meth.2006, 65:10-20. ( IF: 2.4 )
He Zhiguo, Zhong Hui, Hu Yuehua, Xiao Shengmu, Liu Jianshe, Xu Jing, Li Guiyuan. Analysis of differential-expressed proteins ofAcidithiobacillus ferrooxidansgrown under phosphate starvation.J. Biochem. Mol. Biol.2005, 38(5):545-549. ( IF: 1.8 )
He Zhiguo, Hu Yuehua, Zhong Hui, Hu Weixin. Preliminary proteomic analysis ofThiobacillus ferrooxidansgrowing on elemental sulphur and Fe2 separately.J. Biochem. Mol. Biol.2005, 38(3): 307-313. ( IF: 1.8 )
Hu Yuehua,He Zhiguo, Hu Weixin, Zhong Hui. Effect of two kinds of amino acids on metal sulfide bioleaching.Trans.Nonferrous Met.Soc.China.2004, 14(4):794~797. ( IF: 0.33 )
学术会议报告
铜矿生物浸出研究，2011年中国矿产资源节约与综合利用科技发展研讨会（主题报告）。Bioleaching of marmatite by mixed culture ofA.ferrooxidans,A.thiooxidansandA.caldus. 19th International Biohydrometallurgy Symposium, 2011.9.22.
Effect of pH and temperature on the adsorption ofAcidithiobacillus caldus,Leptospirillum ferriphilumandSulfobacillus thermosulfidooxidansonto pyrite. 19th International Biohydrometallurgy Symposium 2011.9.22.
Research on the cell surface proteome response ofMycobacteriato anti-inflamtary drugs. MAP meeting hold in Banff, Alberta, Canada.2008.10.16.
申请专利
贺治国,高凤玲,胡岳华,何超。一种分离纯化Cr6 还原的Ochrobactrum sp.的方法。申请号：**0.5.
贺治国,周珊,胡岳华,顾帼华。一种强酸条件下用于AFM分析的浸矿杆状细菌的固定方法。专利号：**9.0.
李建明，贺治国。一种铬铝中间合金材料的制备方法。专利号：ZL**1.4。
赵恒勤，贺治国，张耀，胡四春，王龙。一种用于铝土矿生物脱硅的新菌种分离培养方法，申请号：**2.9
贺治国，王龙。一种微生物预处理脱除磁化焙烧铁渣中硅杂质提高铁品位的新方法。申请号：**7.3.
学生培养
·博士生：栗树珍(2011);
·硕士生：肖升木(2004); 高凤玲(2006); 李庆华(2006); 王欣（2007），赵健存（2007），朱宁（2007），王丽莎（2008），屈建华（2008），周珊（2008），尹贞（2009），杨彦平（2010），王龙（2011），陈伟基（2011），胡玉婷（2012），王丹（2012），曾强（2013），金明（2013），杨添奇（2013）
出生年月 1978-06职称教授
学历 研究生学位博士
籍贯江西莲花党派中共党员
电话**传真
邮箱zghe@csu.edu.cnQQ**
个人简历
学习工作访学经历
年份
中南大学资源加工与生物工程学院矿物加工工程专业本科
1996.9-2000.7
中南大学资源加工与生物工程学院矿物加工工程专业硕士
2000.9-2002.7
中南大学资源加工与生物工程学院微生物专业博士（提前攻博）
2002.9-2005.6
中南大学资源加工与生物工程学院讲师
2005.6-2006.9
中南大学资源加工与生物工程学院副教授
2006.10-2014.9
加拿大University of Calgary 博士后
2008.3-2010.12
中南大学资源加工与生物工程学院教授、博士生导师
2014年10月-至今
研究方向
矿产资源综合利用及生物冶金
微生物宏基因组学
环境微生物技术
矿冶废水的处理技术及尾矿资源的开发利用
教学方面
主讲本科生 《基因工程》、《生物技术概论》 课程
主讲研究生 《微生物分子生态学》课程
承担课题
基于DNA-稳定同位素探针对腾冲酸性温泉甲烷氧化菌群的宏基因组学研究，国家自然科学基金（No.**）,2014-2017,项目负责人
选矿废水的高效生物处理技术及工艺，教育部“新世纪优秀人才支持计划”， 2013-2015，项目负责人
难处理金矿生物预氧化技术及工艺，2011-2015，中南大学升华“育英计划”青年创新人才资助计划，项目负责人
金属硫化矿浸出专属性微生物多样性与复杂界面作用，国家自然科学基金（No. **）,2014-2017,项目负责人
主要论文(#:标识为通讯作者; IF为SCI期刊影响因子)
Shuzheng Li, Hui Zhong,Zhiguo He#.Microbial community shifts during the process of marmatite bioleaching.Hydrometallurgy. **:127-131.（IF: 2.2)
Shuzheng Li, Hui Zhong,Zhiguo He#. Bioleaching of a low-grade nickel-copper sulfide by mixture of four thermophiles.Bioresource technology.2014, 153:300-6.（IF: 5.04)Zhiguo He,Shuzhen Li,Lisha Wang,Hui ZhongCharacterization of Five Chromium-Removing Bacteria Isolated from Chromium-Contaminated Soil.Water, Air, & Soil Pollution.2014,225: 1904.（IF: 1.7)
Zhiguo He,Yanping Yang,Shan Zhou, Yuehua Hu, Hui Zhong. Effect of pyrite, elemental sulfur and ferrous ions on EPS production by metal sulfide bioleaching microbes.Trans.Nonferrous Met.Soc.China.2014, 24(4):1171-1178.
Ivica Tamas, Angela V Smirnova,Zhiguo He, Peter F Dunfield. The (d)evolution of methanotrophy in the 3 Beijerinckiaceae-a comparative genomics analysis.ISME Journal. 2014, 8(2):369-82. (Nature出版集团旗下期刊，环境领域顶级期刊，IF: 9.27)
Dongshan An,Sean M. Caffrey,Jung Soh,Akhil Agrawal,Damon Brown,Karen Budwill,Xiaoli Dong,Peter F. Dunfield,Julia Foght,Lisa M. Gieg,Steven J. Hallam,Niels W. Hanson,Zhiguo He,Thomas R. Jack,Jonathan Klassen,Kishori M. Konwar,Eugene Kuatsjah,Carmen Li,Steve Larter,Verlyn Leopatra,Camilla L. Nesb,Thomas Oldenburg,Antoine P. Pagé,Esther Ramos-Padron,Fauziah F. Rochman,Alireeza Saidi-Mehrabad,Christoph W. Sensen,Payal Sipahimalani,Young C. Song,Sandra Wilson,Gregor Wolbring,Man-Ling Wong, andGerrit Voordouw. Metagenomics of hydrocarbon resource environments indicates aerobic taxa and genes to be unexpectedly common.Environmental Science & Technology.2013, 47 (18): 10708–10717 (环境领域顶级期刊，影响因子IF=5.48).
Alireza Saidi-Mehrabad*,Zhiguo He*, Ivica Tamas, Christine E Sharp, Allyson L Brady, Fauziah F Rochman, Levente Bodrossy, Guy CJ Abell, Tara Penner, Xiaoli Dong, Christoph W Sensen and Peter F Dunfield.5 Methanotrophic bacteria in oilsands tailings ponds of northern Alberta.ISME Journal. 2013（7）：908-921. *:共同第一作者。(Nature出版集团旗下期刊，环境领域顶级期刊，IF: 9.27)
He Zhiguo, Yang Yanping, Zhou Shan, Zhong Hui, Sun Wei. The effect of culture condition and ionic strength on proton adsorption at the surface of the extreme thermophileAcidianus manzaensis.Colloids and Surfaces B: Biointerfaces.2013, 102: 667-73. ( IF: 4.28 )
He Zhiguo, Yin Zhen, Wang Xin, Zhong Hui, Sun Wei. Microbial community changes during the process of pyrite bioleaching.Hydrometallurgy2012,125–126: 81–89 ( IF: 2.2 )
He Zhiguo,Zhao Jianchun, Hu Yuehua, Qiu Guanzhou. Effect of L-cysteine on the bioleaching of Ni-Cu sulphide byA.manzaensis.J. Cent. Sou. Univ. T.2011, 18(2): 381-385. ( IF: 0.25 )
He Zhiguo, Gao Fengling, Zhao Jianchun, Hu Yuehua, Qiu Guanzhou. Insights into the dynamics of bacterial communities during chalcopyrite bioleaching.FEMS Microbiol. Ecol.2010, 74: 155-164. ( IF: 3.60 )
He Zhiguo, Zhao Jiancun, Gao Fengling, Hu Yuehua, Qiu Guanzhou. Monitoring bacterial community shifts in bioleaching of Ni-Cu sulfide.Bioresour. Technol.2010, 8287-8293 ( IF: 5.04 )
He Zhiguo, De Buck Jeroen. Localization of proteins in the cell wall ofMycobacterium aviumsubsp.paratuberculosisK10 by proteomic analysis.Proteome Sci.2010, 8:21. ( IF: 2.56 )
He Zhiguo, De Buck Jeroen. Cell wall proteome analysis ofMycobacterium smegmatisstrain MC2 155.BMC Microbiol.2010, 10:121. ( IF: 2.88 )
He Zhiguo, Gao Fengling, Zhong Hui, Hu Yuehua. Effects of L-cysteine on Ni–Cu sulfide and marmatite bioleaching byAcidithiobacillus caldus.Bioresour. Technol.2009, 100(3): 1383-1387. ( IF: 5.04 )
He Zhiguo, Gao Fengling, Sha Tao, Hu Yuehua, He Chao. Isolation and characterization of a Cr(VI)-reduction Ochrobactrum sp. strain CSCr-3 from chromium landfill.J. Hazard. Mater.2009, 163: 869-873. ( IF: 4.33 )
Xiao Shengmu, Xie Xuehui, Liu Jianshe,He Zhiguo*, Hu Yuehua. Compositions and structures of archaeal communities in acid mineral bioleaching systems of dongxiang copper mine and yinshan lead–zinc mine.Curr. Microbiol.2008, 57(3):239-44. *corresponding author ( IF: 1.33 )
He Zhiguo, Xiao Shengmu, Xie Xuehui, Hu Yuehua. Microbial diversity in acid mineral bioleaching systems of dongxiang copper mine and Yinshan lead-zinc mine. Extremophiles 2008, 12(2):225-34. ( IF: 2.94 )
Zhong Hui,He Zhiguo, Li Xiaoling, Li Guiyuan. Studies on polyamidoamine dendrimers as efficient gene delivery vector.J. Biomater. Appl.2008, 22 (6): 527-544. ( IF: 1.64 )
He Zhiguo, Zhong Hui, Hu Yuehua, Li Guiyuan. Research on the proteome response ofAcidithiobacillus ferrooxidansto phosphate starvation by SELDI-Protein Chip technologies.Prog. Biochem. Biophys.2008, 35(1):1~8. ( IF: 0.21)
He Zhiguo,Xiao Shengmu, Xie Xuehui, Zhong Hui, Hu Yuehua, Li Qinghua, Gao Fengling, Li Guiyuan, Liu Jianshe, Qiu Guanzhou.Molecular diversity of microbial community in acid mine drainages of yunfu sulfide Mine.Extremophiles2007, 11(2): 305-14. ( IF: 2.94 )
He Zhiguo, Xie Xuehui, Xiao Shengmu, Liu Jianshe, Qiu Guanzhou. Microbial diversity of mine water at Zhong Tiaoshan copper mine,China.J. Basic Microb.2007, 47, 485~495. ( IF: 1.1 )
He Zhiguo, Xie Xuehui, Xiao Shengmu, Liu Jianshe. Microbial populations in acid mineral bioleaching systems of Tong Shankou Copper Mine,China.J. Appl. Microbiol.2007, 103: 1227-1238. ( IF: 2.5 )
He Zhiguo, Zhong Hui, Hu Yuehua, Xiao Shengmu, Xu Jing. Analysis of differential protein expression inAcidithiobacillus ferrooxidansgrown under different energy resources respectively using SELDI-ProteinChip technologies.J. Microbiol. Meth.2006, 65:10-20. ( IF: 2.4 )
He Zhiguo, Zhong Hui, Hu Yuehua, Xiao Shengmu, Liu Jianshe, Xu Jing, Li Guiyuan. Analysis of differential-expressed proteins ofAcidithiobacillus ferrooxidansgrown under phosphate starvation.J. Biochem. Mol. Biol.2005, 38(5):545-549. ( IF: 1.8 )
He Zhiguo, Hu Yuehua, Zhong Hui, Hu Weixin. Preliminary proteomic analysis ofThiobacillus ferrooxidansgrowing on elemental sulphur and Fe2 separately.J. Biochem. Mol. Biol.2005, 38(3): 307-313. ( IF: 1.8 )
Hu Yuehua,He Zhiguo, Hu Weixin, Zhong Hui. Effect of two kinds of amino acids on metal sulfide bioleaching.Trans.Nonferrous Met.Soc.China.2004, 14(4):794~797. ( IF: 0.33 )
学术会议报告
铜矿生物浸出研究，2011年中国矿产资源节约与综合利用科技发展研讨会（主题报告）。Bioleaching of marmatite by mixed culture ofA.ferrooxidans,A.thiooxidansandA.caldus. 19th International Biohydrometallurgy Symposium, 2011.9.22.
Effect of pH and temperature on the adsorption ofAcidithiobacillus caldus,Leptospirillum ferriphilumandSulfobacillus thermosulfidooxidansonto pyrite. 19th International Biohydrometallurgy Symposium 2011.9.22.
Research on the cell surface proteome response ofMycobacteriato anti-inflamtary drugs. MAP meeting hold in Banff, Alberta, Canada.2008.10.16.
申请专利
贺治国,高凤玲,胡岳华,何超。一种分离纯化Cr6 还原的Ochrobactrum sp.的方法。申请号：**0.5.
贺治国,周珊,胡岳华,顾帼华。一种强酸条件下用于AFM分析的浸矿杆状细菌的固定方法。专利号：**9.0.
李建明，贺治国。一种铬铝中间合金材料的制备方法。专利号：ZL**1.4。
赵恒勤，贺治国，张耀，胡四春，王龙。一种用于铝土矿生物脱硅的新菌种分离培养方法，申请号：**2.9
贺治国，王龙。一种微生物预处理脱除磁化焙烧铁渣中硅杂质提高铁品位的新方法。申请号：**7.3.
学生培养
·博士生：栗树珍(2011);
·硕士生：肖升木(2004); 高凤玲(2006); 李庆华(2006); 王欣（2007），赵健存（2007），朱宁（2007），王丽莎（2008），屈建华（2008），周珊（2008），尹贞（2009），杨彦平（2010），王龙（2011），陈伟基（2011），胡玉婷（2012），王丹（2012），曾强（2013），金明（2013），杨添奇（2013）
