张莘莘 讲师

张莘莘，讲师(直聘副教授)，女，1987年10月出生,博士，2014年毕业于南昌大学食品科学与工程专业，获工学博士学位。2009年毕业于南昌大学食品科学与工程专业，获工学学士学位。2013年10月，获得博士研究生出国（境）访学计划项目全额资助，赴新西兰梅西大学Riddet Institute学习13个月。共发表天然产物生理活性及营养相关学术论文14篇，其中第一作者发表SCI收录5篇(其中3篇1区)。目前主持河南省高等学校重点科研项目1项，参与国家自然科学基金项目2项。研究方向为食物营养，天然产物的生理活性，微量元素稳态代谢，营养与疾病等，主要研究活性物质与机体微量元素代谢的关系，包括铁代谢紊乱相关性疾病，免疫相关疾病等。
代表作一览：
(1) Shenshen Zhang, Shaoping Nie,* Danfei Huang, Jianqin Huang, Yanling Feng, Mingyong Xie. A polysaccharide from Ganoderma atrum inhibits tumor growth by induction of apoptosis and activation of immune response in CT26-bearing mice. Journal of Agricultural and Food Chemistry. 2014, 62: 9296-9304.
(2) Shenshen Zhang, Shaoping Nie, Danfei Huang, Yanling Feng, and Mingyong Xie*. A novel polysaccharide from Ganoderma atrum exerts antitumor activity by activating mitochondria-mediated apoptotic pathway and boosting the immune system. Journal of Agricultural and Food Chemistry. 2014, 62(7):1581-1589.
(3) Shenshen Zhang, Shaoping Nie, Danfei Huang, Jianqin Huang, Yanling Feng, and Mingyong Xie*. Ganoderma atrum polysaccharide evokes antitumor activity via cAMP-PKA mediated apoptotic pathway and down-regulation of Ca²⁺/PKC signal pathway. Food and Chemical Toxicology. 2014, 68:239-246.
(4) Shenshen Zhang, Shaoping Nie, Danfei Huang, Jianqin Huang, Yawei Wang. Mingyong Xie*. Polysaccharide from Ganoderma atrum evokes antitumor activity via Toll-like receptor 4-mediated NF-κB and mitogen-activated protein kinase signaling pathways. Journal of Agricultural and Food Chemistry. 2013, 61: 3676-3682.
(5) Shenshen Zhang, Shaoping Nie, Danfei Huang, Wenjuan Li, Mingyong Xie*. Immunomodulatory effect of Ganoderma atrum polysaccharide on CT26 tumor-bearing mice. Food Chemistry. 2013, 136: 1213-1219.
(6) Mingdao Mu, Xiaoyun Shen, Qian Wu, Peng An, Shenshen Zhang, Hao Wang, Yingqi Zhang, Junxia Min, Fudi Wang. The dietary flavonoid myricetin regulates iron homeostasis by suppressing hepcidin expression. Journal of Nutritional Biochemistry. 2016, 30:53-56.
(7) Wenjuan Li, Yi Chen, Shaoping Nie, Mingyong Xie, Ming He, Shenshen Zhang, Kexue Zhu. Ganoderma atrum polysaccharide induces anti-tumor activity via the mitochondrial apoptotic pathway related to activation of host immune response. Journal of Cellular Biochemistry. 2011; 112(3): 860-871.
(8) Wenjuan Li, Shaoping Nie, Mingyong Xie, Shenshen Zhang, Kuxue Zhu. (-)-Epigallocatechin-3-gallate protects neonatal rat cardiomyocytes against oxidative stress induced by anoxia/reoxygenation injury. The 240th ACS National Meeting, Boston, MA USA, August 22-26, 2010.
(9) 张莘莘，聂少平，谢明勇*. 黑灵芝多糖对小鼠结肠癌细胞内cAMP/PKA信号通路的作用.食品科学. 2013, 34(23):11-14.
(10) 张莘莘,李文娟,聂少平,谢明勇*.黑灵芝多糖对体外培养的小鼠腹腔巨噬细胞功能的影响.中国药理学通报.2010, 26(9):1139-1142.