王海波
分析化学，博士，副教授，硕士生导师
教育部学位中心学位论文通讯评议专家
河南省教育厅学术技术带头人
河南省高等学校青年骨干教师
信阳市优秀青年科技专家
办公地点：化学楼522
电话：，**
Email: wanghaibohn@163.com
研究方向：生化分析与生物传感，功能纳米材料与生物纳米技术
教育与研究经历：
王海波，男，1984年12月生，博士，副教授，硕士生导师，教育部学位中心学位论文通讯评议专家，河南省教育厅学术技术带头人，河南省高等学校青年骨干教师，信阳市优秀青年科技专家，校青年骨干教师，入选南湖****奖励计划。2012年6月毕业于湖南大学分析化学专业，获博士学位，师从分析化学专家俞汝勤院士和楚霞教授，2012年7月起任职于信阳师范学院化学化工学院，主要从事生化分析与生物传感技术、纳米生物材料技术和核酸信号放大技术的研究，构建了一系列快速、实时、灵敏的荧光生物传感新方法，并应用于多种重大疾病标记物的高灵敏检测。近年来已在Angewandte Chemie International Edition、Analytical Chemistry、Chemical Communications、Biosensors and Bioelectronics等国际知名分析化学期刊杂志上发表学术论文40余篇，其中IF >5.0的论文14篇，IF >3.0的论文30篇，单篇论文他引200余次。主持国家自然科学基金2项，河南省高等学校青年骨干教师培养计划1项，河南省教育厅科学技术研究重点项目1项，化学生物传感与计量学国家重点实验室开放基金2项，作为主要成员参与国家“863”计划子项目1项、“973”计划子项目1项、国家自然科学基金项目2项，湖南省****基金1项，河南省科技计划项目3项，河南省创新型科技团队和河南省高校科技创新团队各1项。获
河南省优秀硕士学位论文指导教师、河南省自然科学学术论文6项，河南省教育厅优秀科技论文一等奖11项，河南省工业和信息化科技成果奖三等奖1项，信阳市第九届青年科技奖，授权国家发明专利2项。
研究领域与兴趣：
生化分析与生物传感，功能纳米材料与生物纳米技术
教学情况：
研究生：《现代分子光谱分析》、《专业英语》、《化学前沿》
本科生：《仪器分析》、《分析化学实验》、《仪器分析实验》等
授权专利：
1. 国家发明专利（ZL 2013 1 **.9）：王海波，张红定，黄克靖，刘彦明，一种多巴胺－黑色素纳米微球电化学传感器及其制备方法和应用
2. 国家发明专利（ZL 2013 1 **.1）：王海波，张红定，黄克靖，刘彦明，一种黑色素纳米微球－石墨烯电化学传感器及其制备方法和应用
部分获资助项目：
1.国家自然科学基金（U**）：荧光金纳米簇的制备、表征及其在超灵敏生物传感方法中的应用，主持
2.国家自然科学基金（**）：基于上转换荧光纳米材料的超灵敏生物传感新方法研究，主持
3.国家自然科学基金（**）：基于二维过渡金属二硫化物纳米材料超灵敏电化学生物传感器研究，第二
4. 国家自然科学基金（**）：DNA甲基化检测的电化学生物传感新方法研究，第五
5. 河南省高校科技创新团队（15IRTSTHN001）：纳米材料分析，第三
6. 河南省创新型科技团队（C**）：纳米材料分析，第三
代表性论文：
1.Hai-Bo Wang, Qing Zhang, Xia Chu*, Ting-Ting Chen, Jia Ge and Ru-Qin Yu.
Graphene Oxide-Peptide Conjugate as an Intracellular Protease Sensor for Caspase-3 Activation Imaging in Live Cells. Angewandte Chemie International Edition, 2011, 50(31): 7065-7069.
2.Hai-Bo Wang, Shuang Wu, Xia Chu* and Ru-Qin Yu. A Sensitive Fluorescence Strategy for Telomerase Detection in Cancer Cells Based on T7 Exonuclease-Assisted Target Recycling Amplification. Chemical Communications, 2012, 48(47): 5916-5918.
3.Hai-Bo Wang, Ting-Ting Chen, Shuang Wu, Xia Chu* and Ru-Qin Yu.
A Novel Biosensing Strategy for Screening G-Quadruplex Ligands Based on Graphene Oxide sheets. Biosensors and Bioelectronics, 2012, 34: 88-93.
4.Hai-Bo Wang*, Hong-Ding Zhang, Ying Chen and Yan-Ming Liu. A fluorescent biosensor for protein detection based on poly(thymine)-templated copper nanoparticles and terminal protection of small molecule-linked DNA. Biosensors and Bioelectronics, 2015, 74: 581-586.
5.Hai-Bo Wang*, Yang Li, Hong-Yu Bai and Yan-Ming Liu, DNA-templated Au nanoclusters and MnO2 sheets: a label-free and universal fluorescence biosensing platform. Sensors and Actuators B: Chemical, 2018, 259: 204-210.
6.Hai-Bo Wang*, Hong-Ding Zhang, Ying Chen, Ke-Jing Huang and Yan-Ming Liu. A label-free and ultrasensitive fluorescent sensor for dopamine detection based on double-stranded DNA templated copper nanoparticles. Sensors and Actuators B: Chemical, 2015, 220: 146-153.
7.Hai-Bo Wang*, Hong-Ding Zhang, Shu-Ping Xu, Tian Gan, Ke-Jing Huang* and Yan-Ming Liu. A sensitive and label-free electrochemical impedance biosensor for protein detection based on terminal protection of small molecule-linked DNA. Sensors and Actuators B: Chemical, 2014, 194: 478-483.
8.Hai-Bo Wang*, Yang Li, Ying Chen, Zi-Ping Zhang, Tian Gan* and Yan-Ming Liu, Determination of the activity of alkaline phosphatase by using nanoclusters composed of flower-like cobalt oxyhydroxide and copper nanoclusters as fluorescent probes. Microchimica Acta, 2018, 185(2): 102.
9.Hai-Bo Wang*, Yang Li, Hong-Yu Bai, Zi-Ping Zhang, Yong-Hong Li* and Yan-Ming Liu, Development of Rapid and Label-Free Fluorescence Sensing of Tetracyclines in Milk Based on Poly(Adenine) DNA-Templated Au Nanoclusters. Food Analytical Methods, 2018, doi: 10.1007/s12161-018-1289-8
10.Hai-Bo Wang*, Yang Li, Hong-Yu Bai, and Yan-Ming Liu, Fluorescent Determination of Dopamine Using Polythymine-Templated Copper Nanoclusters. Analytical Letters, 2018, doi: 10.1080/**. 2018.**
11.Hai-Bo Wang*, Ying Chen, Na Li and Yan-Ming Liu. A fluorescent glucose bioassay based on the hydrogen peroxide-induced decomposition of a quencher system composed of MnO2 nanosheets and copper nanoclusters. Microchimica Acta, 2017, 184(2): 515-523.
12.Hai-Bo Wang*, Yang Li, Gao-Li Dong, Tian Gan* and Yan-Ming Liu, A convenient and label-free colorimetric assay for dopamine detection based on the inhibition of the Cu(II)-catalyzed oxidation of a 3, 3′, 5, 5′-tetramethylbenzidine-H2O2 system, New Journal of Chemistry, 2017, 41(23): 14364-14369.
13.Hai-Bo Wang*, Ying Chen, Yang Li and Yan-Ming Liu. A sensitive fluorescence sensor for glutathione detection based on MnO2 nanosheets-copper nanoclusters composites. RSC Advances, 2016, 6(83): 79526-79532.
14.Hai-Bo Wang*, Ying Chen, Yang Li and Yan-Ming Liu. Blocking the formation of fluorescent poly(thymine)-templated copper nanoparticles for label-free and sensitive detection of kojic acid in foodstuffs. Analytical Methods, 2016, 8(47): 8322-8328.
15.Hai-Bo Wang*, Hong-Ding Zhang, Yu-Liang Jiang, Xiao-Ling Li and Yan-Ming Liu. Determination of Adenine and Guanine by a Dopamine-Melanin Nanosphere–Polyaniline Nanocomposite Modified Glassy Carbon Electrode. Analytical Letters, 2016, 49(2): 226-235.
16.Hai-Bo Wang*, Hong-Ding Zhang, Yue-Hua Zhang, Huan Chen, Lu-Lu Xu, Ke-Jing Huang and Yan-Ming Liu. Tungsten disulfide nano-flowers/silver nanoparticles composites based electrochemical sensor for theophylline determination. Journal of The Electrochemical Society, 2015, 162(7): B173-B179.
17.Hai-Bo Wang*, Hong-Ding Zhang, Ying Chen, Yang Li and Tian Gan. H2O2-mediated fluorescence quenching of double stranded DNA templated copper nanoparticles for label-free and sensitive detection of glucose. RSC Advances, 2015, 5(95): 77906-77912.
18.Hai-Bo Wang*, Ying Chen, Yang Li, Hong-Ding Zhang and Jun-Tao Cao. A rapid, sensitive and label-free sensor for Hg (II) ions detection based on blocking of cysteine-quenching of fluorescent poly(thymine)-templated copper nanoparticles. RSC Advances, 2015, 5(114): 94099-94104.
19.Hai-Bo Wang*, Hong-Ding Zhang, Ying Chen and Yan-Ming Liu. Inhibition of double-stranded DNA templated copper nanoparticles as label-free fluorescent sensors for L-histidine detection. New Journal of Chemistry, 2015, 39(11): 8896-8900.
20.Hai-Bo Wang*, Hong-Ding Zhang, Ying Chen, Li-Juan Ou* and Yan-Ming Liu. Poly(thymine)-templated fluorescent copper nanoparticles for label-free detection of Nacetylcysteine in pharmaceutical samples. Analytical Methods, 2015, 7(15): 6372-6377.
21.Hai-Bo Wang*, Hong-Ding Zhang, Lu-Lu Xu, Tian Gan, Ke-Jing Huang and Yan-Ming Liu. Electrochemical biosensor for simultaneous determination of guanine and adenine based on dopamine-melanin colloidal nanospheres-graphene composites. Journal of Solid State Electrochemistry, 2014, 18(9): 2435-2442.
22.Hai-Bo Wang*, Lan Wang, Ke-Jing Huang, Shu-Ping Xu, Hong-Qi Wang*, Ling-Ling Wang and Yan-Ming Liu. A highly sensitive and selective biosensing strategy for the detection of Pb2+ ions based on GR-5 DNAzyme functionalized Au NPs. New Journal of Chemistry, 2013, 37(8): 2557-2563.
23.Hai-Bo Wang*, Yong-Hong Li, Ke-Jing Huang, Xin-Sheng Liu, Yan-E Yang and Yan-Ming Liu. A label- free and sensitive fluorescence strategy for screening ligands binding to poly(A) based on exonuclease-I assisted background noise reduction. Analytical Methods, 2013, 5(18): 4852-4858.
24.Hai-Bo Wang*, Li-Juan Ou, Ke-Jing Huang, Xin-Ge Wen, Ling-Ling Wang and Yan-Ming Liu. A sensitive biosensing strategy for DNA detection based on graphene oxide and T7 exonuclease assisted target recycling amplification. Canadian Journal of Chemistry, 2013, 91(12): 1266-1271.