常天俊  
  常天俊，男，汉族，1979年9月生，博士、副教授，资源环境学院硕士生导师。

主要研究方向:    分析化学与生物化学，包括识别生物/污染物分子的高选择性脱氧核酶（DNAzyme）和核酸适配体（aptamer）筛选、识别机制及其应用， G-四链体核酸（G-quadruplex）的结构与分子识别研究。
科研情况:        
[1] 参加国家自然科学基金-河南联合基金重点项目，U**，南水北调中线工程水源地氮沉降特征及其生态效应，2018/01-2021/12，227万元（主持子课题1）；
[2] 主持河南省自然科学基金面上项目，**1，识别金黄色葡萄球菌不同亚种表面共同分子的核酸适配体筛选及应用基础研究，2017/01-2018/12，10万元；
[3] 主持河南理工大学****基金项目，J2017-1，G-四链体核酸的结构和功能研究，2017/01-2019/12，10万元；
[4] 主持河南理工大学高校基本科研业务费项目，面向有害细菌检测的核酸适体应用基础研究，2014.12-2016.12，6万；
[5] 第二完成人（2/11）获得2017年中国分析测试协会科学技术奖二等奖，项目名称“面向活细胞分析的分子探针的构建及应用研究”（2017-2-006-01-R）.

论文情况:     
[1] Tianjun Chang, Weiguo Li, Zhan Ding, Shaofei Cheng, Kun Liang, Xiangjun Liu, Tao Bing, Dihua Shang*. Detection of G-Quadruplex Structures Formed by G-Rich Sequences from Rice Genome and Transcriptome Using Combined Probes. Anal. Chem. 2017, 89(15), 8162−8169 (SCI一区，IF6.320)
[2] Weiguo Li*, Lihui Zhang, Zhan Ding, Guodong Wang, Yandi Zhang, Hongmei Gong, Tianjun Chang, Yanwen Zhang*. De novo sequencing and comparative transcriptome analysis of the male and hermaphroditic flowers provides insights into regulation of flower formation in andromonoecious Taihangia rupestris. BMC Plant Biol. 2017, 17: 54 (SCI二区，IF3.964)
[3] Tianjun Chang, Hongmei Gong, Pi Ding, Xiangjun Liu, Weiguo Li, Tao Bing, Zehui Cao, Dihua Shangguan*. Activity Enhancement of G-quadruplex/Hemin DNAzyme by Flanking d(CCC). Chem. Eur. J. 2016, 22(12), 4015-4021 (Very Important Paper，封面论文；SCI二区，IF5. 317)
[4] Tianjun Chang*, Libo Wang, Kexu Zhao, Yu Ge, Meng He, Gang Li*. Duplex Identification of Staphylococcus Aureus by Aptamer and Gold Nanoparticles. J. Nanosci. Nanotechnol. 2016, 16, 5513-5519 (SCI三区)
[5] Tianjun Chang*, Gang Li, Kexu Zhao, Lin Ban, Wenxiu Bian, Tao Bing, Dihua Shangguan*. Effects of Loops, Flanking Bases and Monovalent Cations on the Structures of G-Quadruplexes, Chem. J. Chinese U. （高等学校化学学报）2014, 35(12):2556-2562 (SCI四区)
[6] 常天俊*，李刚，李卫国. G-四链体核酸的生物学功能，生命的化学, 2014, 34(3): pp 385
[7] Tianjun Chang, Cui Qi, Jie Meng, Nan Zhang, Tao Bing, Xianda Yang, Zehui Cao, Dihua Shangguan*. General Cell-Binding Activity of Intramolecular G-Quadruplexes with Parallel Structure. PLOS ONE 2013, 8(4): e62348 (SCI三区)
[8] Hongcheng Mei, Tao Bing, Cui Qi, Nan Zhang, Xiangjun Liu, Tianjun Chang, Jingli Yan, Dihua Shangguan*. Rational design of Hg²⁺ controlled streptavidin-binding aptamer. Chem. Commun. 2013, 49 (2), 164-166 (SCI一区，IF 6.319)
[9] Jin Zhou, Canliang Fang, Tianjun Chang, Xiangjun Liu，Dihua Shangguan*. A pH sensitive ratiometric fluorophore and its application for monitoring the intracellular and extracellular pHs simultaneously. J. Mater. Chem. B 2013, 1, 661-667 (SCI一区，IF4.513)
[10] Xiangjun Liu, Nan Zhang, Jin Zhou, Tianjun Chang, Canliang Fang, Dihua Shangguan*. A turn-on fluorescent sensor for zinc and cadmium ions based on perylene tetracarboxylic diimide. Analyst 2013, 138 (3), 901-906（SCI二区，IF 3.885）

电子信箱:        changtj@hpu.edu.cn
联系电话:        **