胡建和
职称职务：教授 博士生导师
全国优秀教师，享受河南省政府特殊津贴专家学科专业：动物医学专业
出生年月：1968.09
办公地址：动物科技学院E209
办公电话：0373-**
电子邮件：xxjianhe@126.com
通讯地址：河南省新乡市红旗区河南科技学院动物科技学院
2011-03 至现在，河南科技学院，动物科技学院，教授
2009-03 至2011-02，河南科技学院，动物科学学院，副教授
2008-03 至2009-03，新西兰梅西大学，生命科学学院，访问学
者
2006-11 至2006-12，以色列希伯莱大学参加国际培训
2005-06 至2009-03，河南科技学院，动物科学学院，讲师
2003-06 至2005-05，北京大学生命科学学院，博士后
1998-09 至2003-06，西北农林科技大学，临床兽医学，博士
1988-09 至1992-06，河南农业大学，畜牧专业，学士
兼任教育部高等学校动物医学类专业教学指导委员会委员，中国微生物学会兽医微生物学专业委员会委员，河南省畜牧兽医学会副秘书长、常务理事，河南省人民政府食品安全专家委员会委员，新乡市应急管理公共卫生专家，新乡市非洲猪瘟疫情应急防控专家组成员，新乡市农业技术标准编审委员会评审专家，《动物医学进展》核心期刊编委会委员。获河南省教育系统优秀教师、河南省青年骨干教师、河南省教育厅学术技术带头人、新乡市文明教师等荣誉称号。
从1998 年至今，在动物科技学院预防兽医学教研室从事《兽医
微生物学》和《畜牧微生物学》的教学工作。
动物病原诊断、发病机理和新兽药（抗菌肽）研发。
1. 国家自然科学基金委员会，面上项目，**，抗菌肽BSN-37 佐剂活性的新分子机制研究， 2020-01 至 2023-12，在研， 主持。
2. 国家自然科学基金委员会，面上项目，**，牛源抗菌肽类似物 JH-3 增强小鼠天然免疫防御的分子机制，2017-01 至2018-12，已结题，主持。
3. 国家科学技术部，重点研发计划（子课题），2016YFD**
-4，猪病毒性繁殖障碍相关病原纳米免疫分析分子诊断技术，2016-07
至2020-12，在研，主持。
4. 国家自然科学基金委员会，面上项目，**，动物源性抗菌肽抗菌活性及其溶血性、细胞毒性机制研究，2014-01 至 2014-12，已结题，主持。
5. 河南省科技厅，河南省杰出青年基金，**0028，奶牛抗菌肽的高通量表达及纯化体系研究，2010-01 至 2015-12，已结题， 主持。
6.国家自然科学基金委员会，面上项目，**，猪瘟病毒(石
门株)功能性 T-细胞抗原表位的鉴定与分析, 2007-01至 2007-12，已结题，主持。
[1]Xia Xiaojing, Xin Wang, Shouping Zhang, Yi Zheng, LeiWang, Yanzhao Xu, Bolin Hang, YaweiSun, Liancheng Lei, YueYu Bai*, Jianhe Hu*(通讯作者), miR-31 shuttled by halofuginone-induced exosomessuppresses MFC-7 cell proliferation by modulating the HDAC2/cell cyclesignaling axis. J. Cell. Physiol. 2019 ;234(10).
[2]Xiaojing Xia,Liancheng Lei, Song Wang, Jianhe Hu*(通讯作者), GaipingZhang*. Necroptosis and its role in infectious diseases . Apoptosis 2020, 07.
[3]Xiaojing Xia, Wanhai Qin, Huili Zhu, Xin Wang, JinqingJiang*, Jianhe Hu*(通讯作者). How Streptococcus suis serotype 2 attempts to avoidattack by host immune defenses. J Microbiol ImmunolInfect 2019 ;52(4).
[4]Xiaojing Xia, Xin Wang, Zhe Cheng, Wanhai Qin,Liancheng Lei, Jinqing Jiang and
[5]Lei Wang,Xueqin Zhao, Chunling Zhu, Yaya Zhao, Shuangshuang Liu, Xiaojing Xia, Xin Liu,Huihui Zhang, Yanzhao Xu, Bolin Hang, Yawei Sun, Shijun Chen, Jinqing Jiang,Yueyu Bai, Gaiping Zhang, Liancheng Lei, Langford Paul Richard, Hanna Fotina ,
[6]Lei Yang, YaweiSun*, Yanzhao Xu, Bolin Hang, Lei Wang, Ke Zhen, Bing Hu, Yanan Chen, Xiaojing Xia and Jianhe Hu*(通讯作者). AntibacterialPeptide BSN-37 Kills Extra- and Intra-Cellular Salmonella enterica SerovarTyphimurium by a Nonlytic Mode of Action. Frontiers in Microbiology. 2020, 11:174.
[7]Xia Xiaojing, Wang Xin, Zheng Yi, Jiang Jinqing,Jianhe Hu*(通讯作者).
What role doespyroptosis play in microbial infection? Journal of cellular physiology. 2019,234(6):7885-7892.
[8]Shouping Zhang, Bin Hu, Xiaojing Xia, Yanzhao Xu,Bolin Hang, Jinqing Jiang and
[9]Wang Lei, Zhao Xueqin, Xia Xiaojing, Zhu Chunling,Zhang Huihui, Qin Wanhai, Xu Yanzhao, Hang Bolin, Sun Yawei, Chen Shijun, JiangJinqing, Zhang Gaiping*,
[10]Lei Wang ,Xueqin Zhao, Xiaojing Xia, Chunling Zhu, Wanhai Qin, Yanzhao Xu, Bolin Hang,Yawei Sun, Shijun Chen, Huihui Zhang, Huihui Jiang, jianhe Hu*(通讯作者), HannaFotina, Gaiping Zhang. Antimicrobial PeptideJH-3 Effectively Kills Salmonella enterica Serovar Typhimurium StrainCVCC541 and Reduces Its Pathogenicity in Mice. Probiotics Antimicrob Proteins 2019;11(6).
[11]Wang Qing, Xu Yanzhao, Dong Mengmeng, Hang Bolin, SunYawei, Wang Lei, Wang Yongqiang, Hu Jianhe*(通讯作者), Zhang Wenju *.HJH-1, a
Broad-SpectrumAntimicrobial Activity and Low Cytotoxicity Antimicrobial Peptide. Molecules,2018, 23(8):e2026.
[12]Xia Xiaojing, Wang Lei, Zhang Xiaojian, Wang Shan, LeiLiancheng, Cheng Likun, Xu Yanzhao, Sun Yawei, Hang Bolin, Zhang Gaiping*, BaiYueyu*, Hu Jianhe*(通讯作者). Halofuginone-induced autophagy suppresses the migration andinvasion of MCF-7 cells via regulation of STMN1 and p53. Journal of cellularbiochemistry. 2018, 119(5):4009-4020.
[13]Xia Xiaojing, Lei Liancheng,Qin Wanhai, Wang Lei, Zhang Gaiping*, HuJianhe*(通讯作者). GCN2 controls the cellularcheckpoint: potential target for regulating inflammation. Cell DeathDiscovery. 2018, 4:20.
[14]Xia Xiaojing, Wang Xin, Wei Xiaobin, Jiang Jinqing,Hu Jianhe*(通讯作者 ). Methods for the detectionand characterization of Streptococcus suis: from conventional bacterial culturemethods to immunosensors. Antonie van Leeuwenhoek. 2018, 111(12):2233-2247.
[15]Xia Xiaojing, Cheng Likun, Zhang Shouping. Wang Lei,
作者). Therole of natural antimicrobial peptides during infection and chronicinflammation. Antonie van Leeuwenhoek. 2018, 111(1):5-26.
[16]Wang Yongqiang, Zhang Wenju, Nie Cunxi, Chen Cheng,Zhang Xiaoyang, Hu Jianhe. Evaluation of sample extracting methods of FCSM byLactobacillus acidophilus based on a UPLC-Q-TOF-MS global metabolomicsanalysis. 2018, 49(2):392-400.
[17] XiaXiaojing, Zhang Huihui, Cheng Likun, Zhang Shouping, Wang Lei, Li Shuguang, Shen Zhiqiang, Zhang Gaiping,Hu Jianhe*(通讯作者). Development of PPA-ELISA for Diagnosing Streptococcussuis Infection Using Recombinant Sao-M Protein As Diagnostic Antigen. KafkasUniv Vet Fak Derg. 2017, 23(6):989-996.
[18]Wang Qiuxia, Ou Changbo, Dou Yongxi, Chen Lei, MengXuelian, Liu Xingyou, Yu Yan, Jiang Jinqing, Ma Jinyou, Zhang Zhidong,
[19]Xia Xiaojing, Wang Lei, Shen Zhiqiang*, Qin Wanhai,
[20]Wang Lei, Zhao Xueqin, Zhu Chunling, Xia Xiaojing, QinWanhai, Xu Yanzhao, Hang Bolin, Sun Yawei, Jiang Jinqing, Langford PaulRichard, Liancheng Lei, Gaiping Zhang,Jianhe Hu*(通讯作者). Thymol killsbacteria, reduces biofilm formation, and protects miceagainst a fatal infection of Actinobacillus pleuropneumoniae strain L20[J].Veterinary Microbiology, 2017, 203: 202-210.
[21]Wang Lan, Xu Minglu, Liu Jie, Wang You,
[22] ZhangQinghua, Xu Yanzhao, Wang Qing, Hang, Bolin, Sun, Yawei, Wei Xiaoxiao, HuJianhe*(通讯作者). Potential of novel antimicrobial peptideP3 from bovine erythrocytesand its analogs to disrupt bacterial membranes in vitro and
display activityagainst drug-resistant bacteria in a mouse model. Antimicrobial agents andchemotherapy. 2015, 59(5):2835-2841.
[23]Yanzhao Xu, Qing Wang, Bolin Hang, Dengfeng Fu,Tiantian Shang, Zhiyu Zhao, QinghuaZhang,Jianhe Hu*( 通 讯 作 者 ). SerialExpression and Activity Analysis of LNK-16: A Bovine Antimicrobial PeptideAnalogue. Protein J. 2014, 33(4).
[24]胡建和；杭柏林；徐彦召；孙亚伟等；《动物微生物学(英文版)》，科学出版社，2017.(河南省“十二五”普通高等教育规划教材)
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