课题组长：张学斌，男，博士，教授，博士生导师。
联系电话：86-**
E-mail：xuebinzhang@henu.edu.cn; 或者xuebin.zhang2000@gmail.com


课题组核心成员：
禹坷（校****）；赵兵（讲师）；张君丽（讲师）；杨文奇（博士后）；秦海霞（博士生）；蔡亚玲（博士生）；
兰琛（科研助理）；毛熙岚（科研助理）


主要成就和研究专长：
1998至 2005年就读于山西农业大学食品科学与工程学院及文理学院。2005年起就读于英国诺丁汉大学植物科学系，2008年获英国诺丁汉大学理学博士学位。2008至 2011年在英国洛桑实验站（Rothamsted Research）从事博士后工作。2011年3月至2018年4月就职于美国国家能源部布鲁克海文国家实验室（Brookhaven National Laboratory）。2018年5月至今受聘于河南大学生命科学学院****。主要从事植物苯丙素类化合物合成途径调控和F-box基因家族功能解析方面的研究。分离并鉴定了多个直接控制苯丙素合成途径关键结构酶蛋白降解的F-BOX 基因；该类研究成果引领了植物苯丙素类化合物合成过程中蛋白降解调控机制的研究。在Nature Communications, Plant Biotechnology, The Plant Cell，Plant Physiology，Molecular plant， Biochemical Journal，FEBS letter等国际知名学术期刊发表研究论文29篇。申请发明专利2项。


主持的重要研究项目：
河南大学人才特区支持计划（2018-2023）；
国家自然科学基金面上项目（2020-2023）。


所获荣誉：
河南省****；
国家人社部高层次留学人才。


代表性研究论文和著作(*为通讯作者)：
1. X Wang, M Wang, X Xie, S Guo, Y Zhou, X Zhang*, N Yu*, E Wang*. (2020）An amplification-selection model for quantified rhizosphere microbiota assembly. Science Bulletin
2. Xiaozong Wu, Hongli Li, Yan Wang, Xuebin Zhang*. (2020) Effects of bio-organic fertiliser forti?ed by Bacillus cereus QJ-1 on tobacco bacterial wilt control and soil quality improvement. Biocontrol Science and Technology
3. Zhang S, Tian Z, Li H, Guo Y, Zhang Y, Roberts JA, Zhang X*, Miao Y*. (2019) Genome-wide analysis and characterization of F-box gene family in Gossypium hirsutum L. BMC Genomics
4. Zhang S, Cai Y, Guo J, Li K, Peng R, Liu F, Roberts JA, Miao Y*, Zhang X*. (2019) Gossypium hirsutumGenotyping-by-Sequencing of Races and Cultivars Uncovers Novel Patterns of Genetic Relationships and Domestication Footprints. Evol. Bioinform
5. Li W, Zhang J, Zhu W, Qin P, Zhou Q, Lu M, Zhang X, Zhao W, Zhang S, Cai Z. (2020) Facile preparation of reduced graphene oxide/ZnFeO nanocomposite as magnetic sorbents for enrichment of estrogens. Talanta
6. Zhang X*, Gonzalez-Carranza H. Z, Zhang S, Miao Y, Liu C, Roberts J. (2019). F-box proteins in plants. Annual Plant Review online, February, 2019
7. Zhang, X, Zhang, J, Li, W, Yang, Y, Qin, P, Zhang, X, Lu, M. (2018) Magnetic graphene oxide nanocomposites as the adsorbent for extraction and pre-concentration of azo dyes in different food samples followed by high-performance liquid chromatography analysis. Food Additives & Contaminants: Part A. 2018
8. Zhang, X., Jayaweera D, Peters J L, Szecsi J, Bendahmane M, Roberts J A, González-Carranza Z H*. (2017). The Arabidopsis thaliana F-box gene HAWAIIAN SKIRT is a new player in the microRNA pathway. PLoS ONE , 2017, IF: 2.806
9. Zhang, X., Abrahanb, C., Colquhounb, T.A and Liu, C. (2017). A Proteolytic Regulator Controlling Chalcone Synthase Stability and Flavonoid Biosynthesis in Arabidopsis. The Plant Cell, May, 2017. IF 10.125. (*Editor’s choice of cover story of the month)
10. Zhang, X., Gou, M., Guo, C., Yang H., and Liu, C. (2015). Down-regulation of the kelch domaincontaining F-box protein in Arabidopsis enhances the production of (poly)phenols and tolerance to UV-radiation. Plant Physiology, January, 2015. IF: 7.908.
11. Zhang, X., and Liu, C. (2014). Multifaceted regulations of gateway enzymes in the biosynthesis of phenylpropanoids. Molecular Plant, November, 2014. IF: 6.126.
12. Zhang, X., Gou, M., Liu, C. (2013). Kelch Repeat F-box Proteins Regulate Phenylpropanoid Biosynthesis via Controlling the Turnover of Phenylalanine Ammonia-Lyase. The Plant Cell, 25, 4994-5010. IF 10.125.
13. Zhang, X., De Marcos Lousa, C., Shutte-Lensink, N., Ofman, R., Wanders, R.J., Baldwin, S.A., Baker, A., Kemp, S., and Theodoulou, F.L. (2011), Conservation of targeting but divergence in function and quality control of peroxisomal ABC transporters: an analysis using crosskingdom expression. Biochemical Journal, 436, 547-57. IF: 5.0.
14. Nyathi, Y*., Zhang, X*., Baldwin, J.M., Bernhardt, K., Johnson, B., Baldwin, S.A., Theodoulou, F.L., and Baker, A. (2012). Pseudo half-molecules of the ABC transporter, COMATOSE, bind Pex19 and target to peroxisomes independently but both are required for activity. FEBS Letters. 586, 2280-2286. (*co-first author). IF: 4.0.
15. Cheng A, Zhang X, Han X-J, Zhang Y-Y, Gao S, Liu C-J, Lou H. (2017) Identification of Chalcone Isomerase in the Basal Land Plants Reveals an Ancient Evolution of Enzymatic Cyclization Activity for Synthesis of Flavonoids. New Phytologist , September, 2017, IF: 7.330
16. Gonzalez-Carranza H Z *, Zhang X， Peters L J，Veronique Szecsi B, Bendahmane J, M， Roberts A J. (2017) Hawaiian skirt controls size and floral organ number by modulating CUC1 and CUC2 expression. PLoS ONE ,September 20, 2017, IF: 2.806
17. Gou, M., Hou, G., Yang, H., Zhang, X, Cai, Y., Kai, G and Liu, C. (2016). The MYB107 transcription factor positively regulates suberin biosynthesis. Plant Physiology, December, 2016. IF: 7.908.
18. Cai, Y., Zhang, K., Kim, H., Hou, G., Zhang, X., Yang, H., Feng, H., Miller, L., Ralph, J & Liu, C. (2016). Enhancing digestibility and ethanol yield of Populus wood via expression of an engineered monolignol 4-O-methyltransferase. Nature Communications, Article number 11989. IF: 10.2.
19. Liu, C., Cai, Y., Zhang, X., Gou, M., and Yang, H. (2014). Tailoring lignin biosynthesis for efficient and sustainable biofuel production. Plant Biotechnology Journal, September, 2014. IF: 6.279.
20. Mendiondo, G.M., Medhurst, A., Roermund, C.W., Zhang, X., Devonshire, J., Scholefield, D., Fernández, J., Axcell, B., Ramsay, L., Waterham, H.R., Waugh, R., Theodoulou, F.L. and Holdsworth, M.J. (2014). Barley has two peroxisomal ABC transporters with multiple functions in β-oxidation. Journal of Experimental Botany, June 9, 2014. IF: 5.542.
21. Zhang, K., Novak, O., Wei, Z., Gou, M., Zhang, X., Yu, Y., Yang, H., Cai, Y., Strnad, M., and Liu, C. (2014). Arabidopsis ABCG14 protein controls the acropetal translocation of root-synthesized cytokinins. Nature Communications, Article number 3274. IF: 10.2.
22. Fan, J., Yan, C., Zhang, X., and Xu, C. (2013). Dual Role for Phospholipid:Diacylglycerol Acyltransferase: Enhancing Fatty Acid Synthesis and Diverting Fatty Acids from Membrane Lipids to Triacylglycerol in Arabidopsis Leaves. The Plant Cell, 25, 3506-18.IF: 10.125.
23. Theodoulou, F.L., Nyathi, Y., van Roermund, C., Lousa, C.D., Linka, N., Zhang, X., Haslam, R., Napier, J.A., Baldwin, S.A., Weber, A., and Baker, A. (2010). Peroxisomal transporters associated with beta-oxidation. Biochimica et Biophysica Acta-Bioenergetics 1797,145154, IF: 5.0.


著作:
Theodoulou, F.L., Zhang, X., De Marcos Lousa, C., Nyathi, Y., and Baker, A. (2011). Peroxisomal transport systems: roles in signalling and metabolism. In: Transporters and pumps in plant signalling. Eds. Markus Geisler and Kees Venema. Signaling and Communication in Plants 7, Springer-Verlag Berlin Heidelberg. pp 327-351


专利
“Enhancing Oil Accumulation in Vegetative Tissue of Plants” Publication number: US 2014/** A1 (US department of Energy); Publication date: Jan. 30, 2014.


重要奖项：
Spot Light Award in BNL, USA (2014)
Top-10 Brookhaven National Laboratory Breakthroughs (2013)
Company of Biologists. Travel award to attend the SEB annual meeting in Prague (2010)
Great Britain-China Education Trust student award (2007)
PhD studentship. The University of Nottingham (2005)


在国际学术会议做重要报告等情况：
Zhang X., Gonzalez-Carranza Z.H., Roberts J. A. (2007). Identifying potential target proteins for degradation regulated by the Hawaiian Skirt gene (HWS). 18th International Conference On Arabidopsis Research, Beijing, China, 2007. TAIR Publication: （第18届国际拟南芥大会）
González-Carranza, Z.H., Zhang X., Roberts J.A. (2008). The F-box protein HAWAIIAN SKIRT regulates boundary fusion via miRNA processing. Comparative Biochemistry and Physiology, PART A, 150, P3.12 S189.
González-Carranza, Z.H., Zhang X., Peters J.L., Roberts J.A. (2009). Interaction between the ubiquitination and miRNA pathways in the regulation of flower development. 20th International Conference in Arabidopsis Research, P037, P12. （第20届国际拟南芥大会）
González-Carranza, Z.H., Zhang X., Peters J.L., Roberts J.A. (2009). ... Love me, love me not... a way to increase petal numbers from Arabidopsis. Workshop in mechanisms Controlling Flower Development, 31.
Zhang X., Marcos Lousa C.D., Baldwin S.A., Baker A., Theodoulou F.L. (2010). Cross‐kingdom Characterisation of Peroxisomal ABC transporters. Society for Experimental Biology annual meeting, Prague, CZ. （英国实验生物学学会，2010年会）
Zhang X., Marcos Lousa C.D., Baldwin S.A., Baker A., Theodoulou F.L. (2010). Cross‐kingdom Characterisation of Peroxisomal ABC transporters. Open European Peroxisome Meeting (OEPM 2010), Lunteren, The Netherlands. (欧洲过氧化物酶体会议)
Attendance to: GARNet 2010 meeting, Durham University, UK, September 2010 （英国实验生物学学会）BBSRC Next Generation Conference (Career Snapshots workshop), Manchester, UK, November 2010 （英国生物技术学会，青年****会议）
Zhang X., Liu C. (2015) Post-translational modification of Arabidopsis S-adenosylmethionine synthetase (SAMS). Plant Metabolic Engineering-Harnessing Plant Metabolism for the Bio-Based Economy, Gordon Research Conference, July 19-24, 2015. Waterville Valley, Waterville Valley, NH
Zhang X., Liu C. (2017) The F-Box Protein-mediated Proteolytic Regulation of Flavonoid Biosynthesis in Arabidopsis. The 4th International Conference on Plant Metabolism (ICPM 2017) July 16-20, 2017. Dalian International Conference Center, China





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