姓 名： 夏晓华
职 称： 副教授（硕导）
办公电话： **

电子邮箱： xxhlpf@163.com








个人简介：
2011年7月到河南师范大学生命科学学院遗传微生物教研室任职。主讲本科生《普通遗传学》、《基因工程》和研究生《生物反应器工程》等课程。研究方向为动物分子遗传学，主要从事动物性别调控、以及环境毒理等研究。先后在SCI及核心以上期刊发表论文三十余篇，主持国家自然科学基金、教育厅项目、横向合作项目和校级项目5项。

研究领域：
1.动物性别决定和分化；2.水生环境毒理学；
3.动物免疫机制研究。
主要学术及社会兼职：
中国遗传学会会员
河南遗传学会理事
主持或参加科研项目情况：
1.两种泥鳅DMRT1基因不同选择性剪接体的结构、功能及调控机制（**），国家自然科学基金项目，2013-2015，主持
2.大鳞副泥鳅DMRT1基因不同选择性剪接体的表达模式分析（12B180011），河南省教育厅项目，2012-2014，主持
3.两种泥鳅DMRT1基因不同选择性剪接体的克隆和表达模式分析，天津市细胞遗传与分子调控重点实验室开放基金项目，2012-2014，主持
4.泥鳅DMRT1基因不同剪接体的克隆和时空表达模式分析，河南师范大学博士科研启动费支持课题，2012-2014，主持
5.大鳞副泥鳅DMRT1基因5′侧翼区的克隆及核心启动子活性分析，河南师范大学青年科学基金项目，2012-2015，主持
学术成果：
代表性论文：
1. Xiaohua Xia, Ruyan Wan,Peijin Wang, Weiran Huo, Hui Dong, Qiyan Du. Toxicity of imidazoles ionicliquid [C16mim]Cl to Hela cells. Ecotoxicology and Environmental Safety. 2018,162: 408–414.2. Xiaohua Xia, Peijin Wang,Ruyan Wan, Weiran Huo, Zhongjie Chang. Toxic effects of cyhalofop-butyl onembryos of the Yellow River Carp (Cyprinus carpio var.): Alters embryoshatching, development failure, mortality of embryos and apoptosis.Environmental science and pollution research. 2018, 25: 24305–24315.
3. Xiaohua Xia, Weiran Huo,Ruyan Wan, Linxia Zhang, Xiaopei xia, Zhongjie Chang. Molecular cloning andexpression analysis of Sox3 during gonad and embryonic development in Misgurnusanguillicaudatus. International Journal of Developmental Biology. 2017, 61:565-570.
4.Xiaohua Xia, Weiran Huo, Ruyan Wan, Peijin Wang, LinxiaZhang, Zhongjie Chang. Molecular cloning, characterization, and expressionprofiles of the Sox3 gene in Chinese loach Paramisgurnus dabryanus. Evolution& Development. 2018, 20:108-118.
5. Xiaohua Xia, Peijin Wang, Ruyan Wan, Zhongjie Chang, QiyanDu. Progesterone affects sex differentiation and alters transcriptional ofgenes along circadian rhythm signaling and hypothalamic-pituitary-gonadal axesin juvenile Yellow River Carp (Cyprinus carpio var.).Environmental Toxicology.2019,34:1255–1262.
6. Xiaohua Xia, Weiran Huo, Ruyan Wan, Peijin Wang, ZhongjieChang. Cloning, characterization and function analysis of DAX1 in Chinese loach(Paramisgurnus dabryanus). Genetica.2018,146:487–496
7. Xiaohua Xia, Xiaopei Xia, Weiran Huo, Hui Dong, Linxia Zhang,Zhongjie Chang. 2016, Toxic effects of imidacloprid on adult loach (Misgurnusanguillicaudatus). Environmental Toxicology and Pharmacology, 45: 132–139.
8. Xiaohua Xia,Ruyan Wan, Weiran Huo, Linxia Zhang, Xiaopei Xia, Zhongjie Chang. Molecularcloning and mRNA expression pattern of Sox4 in Paramisgurnus dabryanus. GeneExpression Patterns. 2017, 25-26:109–117.
9. Xiaohua Xia,Ruyan Wan, Weiran Huo, Linxia Zhang, Xiaopei Xia, Zhongjie Chang. Molecularcloning and mRNA expression pattern of Sox4 in Misgurnus anguillicaudatus.Journal of genetics. Vol. 97, No. 4, September 2018, pp. 869–877.
10. Xiaohua Xia,Weiran Huo, Ruyan Wan, Xiaopei xia, Qiyan Du, Zhongjie Chang*. Identificationof housekeeping genes as references for quantitative real-time RT-PCR analysisin Misgurnus anguillicaudatus. Journal of Genetics. 2017, 96(6): 895-904.
11. Xiaohua Xia, Xiaopei Xia, Weiran Huo, Hui Dong, Linxia Zhang,Zhongjie Chang. 2016, Toxic effects of imidacloprid on adult loach (Misgurnusanguillicaudatus). Environmental Toxicology and Pharmacology, 45: 132–139.(SCI)
12. XiaohuaXia, Jianjun Chen, Linxia Zhang, Qiyan Du, Jinsheng Sun, Zhongjie Chang,2013. Molecular cloning and mRNA expression pattern of Sox10 in Paramisgurnusdabryanus. Molecular Biology Reports, 40( 4): 3123-3134.
13. XiaohuaXia, Ping Nan, Linxia Zhang, Jinsheng Sun, Zhongjie Chang, 2013. Homologueof Sox10 in Misgurnus anguillicaudatus: Sequence, expression pattern duringearly embryogenesis. Fish Physiology and Biochemistry, 39:1341–1351.
14. XiaohuaXia, Jie Zhao, Qiyan Du, Zhongjie Chang, 2011. Isolation and expression oftwo distinct Sox8 genes in mudloach (Misgurnus anguillicaudatus). BiochemicalGenetics,49(3-4): 161-176.
15. Ruyan Wan, XiaohuaXia*, Peijin Wang, Weiran Huo, Hui Dong, Zhongjie Chang. Toxicity ofimidazoles ionic liquid [C16mim]Cl to HepG2 cells. Toxicology in Vitro. 2018,52: 1–7.通讯作者
16. Weiran Huo, Ruyan Wan, Peijin Wang, Linxia Zhang, Xiaohua Xia*.Molecular cloning, characterization of dax1 gene and its response toProgesterone in Misgurnus anguillicaudatus. Drug and Chemical Toxicology. 2019,42(6):624–633.通讯作者