刘胜旺*
性 别： 男 出生年月： 1969-07-04
职 称： 研究员 工作单位： 中国农业科学院哈尔滨兽医研究所
招生学科1： 微生物学 招生学科2： 微生物学
办公电话： ** E-mail： swliu@hvri.ac.cn

 开设研究生课程情况
课程编号 课程名称 课程级别 学时
 近五年主持科研项目概况
1、现代农业产业技术体系，蛋鸡产业疫病控制，350万元；
2、国家科技支撑计划课题，禽流感等重要家禽疫病流行毒疫苗研究与开发，86.25万元；
3、基础支撑科研专项，禽呼吸道病创新团队，591.45万元；
4、公益性行业（农业）科研专项，鸡新城疫防控技术研究与示范，108万元；
5、哈尔滨市科技攻关计划项目，新城疫和传染性支气管炎二联疫苗，70万元

 近五年项目获奖概况
（1）中国鸡传染性支气管病毒流行、变异机制及毒株资源库的建立，黑龙江省科学技术奖，自然科学奖，一等奖，2015
（2）新型禽用疫苗与诊断试剂研究团队奖，中华农业科技奖，优秀创新团队奖（等同于科研成果一等奖），2013


 近五年代表性著作、论文
（1）Zongxi Han, Tingting Zhang, Qianqian Xu, Mengying Gao, Yuqiu Chen, Qiuling Wang, Yan Zhao, Yuhao Shao, Huixin Li, Xiangang Kong, Shengwang Liu*, Altered pathogenicity of a tl/CH/LDT3/03 genotype infectious bronchitis coronavirus due to natural recombination in the 5′- 17 kb region of the genome. Virus Research，Virus Research,2016,213:140-148
(2) Hai Li , Fengjie Wang , Zongxi Han, Qi Gao, Huixin Li, Yuhao Shao, Nana Sun and Shengwang Liu. Genome-wide gene expression analysis identifies the proto-oncogene tyrosine-protein kinase Src as a crucial virulence determinant of the infectious laryngotracheitis virus in chicken cells. Journal of Virology, 2016, 90(1):9-21
(3) Lingfeng Chen, Tingting Zhang, Zongxi Han, Xiangang Kong, Shengwang Liu. Molecular and antigenic characteristics of Massachusetts genotype infectious bronchitis coronavirus in China. Veterinary Microbiology,2015,181(3-4):241-251  
(4) Qianqian Xu, Zongxi Han, Qiuling Wang, Tingting Zhang, Mengying Gao, Yan Zhao, Yuhao Shao, Huixin Li, Xiangang Kong , Shengwang Liu*, Emergence of Novel Nephropathogenic Infectious Bronchitis Viruses Currently Circulating in Chinese Chicken Flocks, Avian Pathology. 2015, 9:1-37
(5) Yanyan Li, Qianqian Xu, Tingting Zhang, Mengying Gao, Qiuling Wang, Zongxi Han, Yuhao Shao, Deying Ma and Shengwang Liu, Host Avian Beta-Defensin and Toll-Like Receptor Responses of Pigeons following Infection with Pigeon Paramyxovirus Type 1, Applied and Environmental Microbiology, 2015, 81(18):6415-6424
(6) Yang Xu, Tingting Zhang, Qianqian Xu, Zongxi Han, Shuling Liang, Yuhao Shao, Deying Ma ,Shengwang Liu*,Differential modulation of avian β-defensin and Toll-like receptor expression in chickens infected with infectious bronchitis virus, Applied and Microbiology Biotechnology 2015, 99(21):9011-9024
(7) Tingting Zhang, Zongxi Han, Qianqian Xu, Qiuling Wang, Mengying Gao, Wei Wu, Yuhao Shao, Huixin Li, Xiangang Kong, Shengwang Liu*, Serotype shift of a 793/B genotype infectious bronchitis coronavirus by natural recombination, Infection, Genetics and Evolution, 2015, 32:377-387
(8) Wei Wu, Huairan Liu, Tingting Zhang, Zongxi Han, Yanyu Jiang, Qianqian Xu, Yuhao Shao, Huixin Li, Xiangang Kong, Hongyan Chen*, Shengwang Liu* , Molecular and antigenic characteristics of Newcastle disease virus isolates from domestic ducks in China, Infection, Genetics and Evolution,2015, 32:34-43
(9) Fei Zhao, Zongxi Han, Tingting Zhang, Yushao Hao, Xiangang Kong, Huijie Ma, Shengwang Liu*, Genomic characteristics and changes of avian infectious bronchitis virus strain CK/CH/LDL/97I after serial passages in chicken embryos, Intervirology,2014, 57(6):319-330
(10) Shengwang Liu*, Qianqian Xu, Zongxi Han, Xiaoli Liu, Huixin Li, Hongbo Guo, Nana Sun, Yuhao Shao, Xiangang Kong, Origin and characteristics of the recombinant novel avian infectious bronchitis coronavirus isolate ck/CH/LJL/111054, Infection, Genetics and Evolution,  2014, 23: 189-195
(11) Junfeng Sun, Zongxi Han, Yuhao Shao, Zhongzan Cao, Xiangang Kong , Shengwang Liu*, Comparative proteome analysis of tracheal tissues in response to infectious bronchitis coronavirus, Newcastle disease virus, and avian influenza virus H9 subtype virus infection, Proteomics,2014, 14(11):1403-1423
(12) Hongbo Guo, Xiaoli Liu, Yang Xu, Zongxi Han, Yuhao Shao, Xiangang Kong, Shengwang Liu*, A comparative study of pigeons and chickens experimentally infected with PPMV-1 to determine antigenic relationships between PPMV-1 and NDV strains, Veterinary Microbiology, 2014, 168(1):88-97
(13) Feng Cong, Xiaoli Liu, Zongxi Han, Yuhao Shao, Xiangang Kong, Shengwang Liu*, Transcriptome analysis of chicken kidney tissues following coronavirus avian infectious bronchitis virus infection, BMC Genomics, 2013, 14:743
(14) Hongbo Guo, Xiaoli Liu, Zongxi Han, Yuhao Shao, Jinding Chen, Shasha Zhao, Xiangang Kong , Shengwang Liu*, Phylogenetic analysis and comparison of eight strains of pigeonparamyxovirus type 1 (PPMV-1) isolated in China between 2010 and 2012, Archieves of Virology,2013, 158(6):1121-1131
(15) Xiaoli Liu, Huijie Ma, Qianqian Xu, Nana Sun, Zongxi Han, Chuyang Sun, Hongbo Guo,Yuhao Shao, Xiangang Kong, Shengwang Liu *, Characterization of a recombinant coronavirus infectious bronchitis virus with distinct S1 subunits of spike and nucleocapsid genes and a 3′-untranslated region,Veterinary Microbiology. 2013, 162(2-4):429-436
(16) Xiaoli Liu, Yuhao Shao, Huijie Ma, Chuyang Sun, Xiaonan Zhang, Chengren Li, Zongxi Han, Baolong Yan, Xiangang Kong, Shengwang Liu*, Comparative analysis of four Massachusetts type infectious bronchitis coronavirus genomes reveals a novel Massachusetts type strain and evidence of natural recombination in the genome, Infection, Genetics and Evolution, 2013,14:29-38
(17) Deying Ma*, Mingyue Zhang, Kexin Zhang, Xiaoli Liu, Zongxi Han, Yuhao Shao, Shengwang Liu*,Identification of three novel avian beta-defensins from goose and their significance in the pathogenesis of Salmonella. Molecular Immunology, 2013 ,56(4):521-529
（18）Zongxi Han, Fei Zhao, Yuhao Shao, Xiaoli Liu, Xiangang Kong, Yang Song, Shengwang Liu*, Fine level epitope mapping and conservation analysis of two novel linear B-cell epitopes of the avian infectious bronchitis coronavirus nucleocapsid protein. Virus Research，2013,171(1):54-64  
(19) Deying Ma*, Kexin Zhang, Mingyue Zhang, Shengnan Xin, Xiaoli Liu, Zongxi Han, Yuhao Shao, Shengwang Liu*. Identification, Expression and Activity Analyses of Five Novel Duck Beta-Defensins, PLoS One. 2012 ,7 (10):e47743
(20) Huijie Ma, Yuhao Shao, Chuyang Sun, Zongxi Han, Xiaoli Liu, Hongbo Guo, Xiaozhen Liu, Xiangang Kong, Shengwang Liu*, Genetic diversity of avian infectious bronchitis coronavirus in recent years in China, Avian Diseases,2012, 56(1):15-28
(21) Zhongzan Cao, Zongxi Han, Yuhao Shao, Xiaoli Liu, Junfeng Sun, Dan Yu, Xiangang Kong, Shengwang Liu*. Proteomics analysis of differentially expressed proteins in chicken trachea and kidney after infection with the highly virulent and attenuated coronavirus infectious bronchitis virus in vivo. Proteome Science, 2012 , 10:24
(22) Zhongzan Cao, Zongxi Han, Yuhao Shao, Heyuan Geng, Xiangang Kong, Shengwang Liu*. Proteomic analysis of chicken embryonic trachea and kidney tissues after infection in ovo by avian infectious bronchitis coronavirus. Proteome Science, 2011, 9:11
(23) Chuyang Sun, Zongxi Han, Huijie Ma, Qingxia Zhang, Baolong Yan, Yuhao Shao, Jia Xu, Xiangang Kong, Shengwang Liu*, Phylogenetic analysis of infectious bronchitis coronaviruses newly isolated in China, and pathogenicity and evaluation of protection induced by Massachusetts serotype H120 vaccine against QX-like strains, Avian Pathology, 2011,40(1):43-54
(24) Deying Ma, Caiyuan Zhou, Mingyue Zhang, Zongxi Han, Yuhao Shao,Shengwang Liu*, Functional analysis and induction of four novel goose (Anser cygnoides) avian β-defensins in response to salmonella enteritidis infection, Comparative Immunology, Microbiology and Infectious Diseases,2012， 35(2):197-207
(25) Deying Ma, Lijuan Lin, Kexin Zhang, Zongxi Han, Yuhao Shao, Ruiqin Wang, Shengwang Liu* ,Discovery and characterization of Coturnix chinensis avian β-defensin 10, with broad antibacterial activity , Journal of Peptide Science, 2012;18(4):224-232
(26) Xiaoli Liu, Zongxi Han, Yuhao Shao, Yang Li, Huixin Li, Xiangang Kong,Shengwang Liu. Different linkages in the long and short regions of the genomes of duck enteritis virus Clone-03 and VAC strains, Virology Journal, 2011,8:200
(27) Deying Ma, Lijuan Lin, Keixn Zhang, Zongxi Han,Yuhao Shao, Xiaoli Liu, Shengwang Liu*，Three novel Anas platyrhynchos avian β-defensins, upregulated by duck hepatitis virus, with antibacterial and antiviral activities, Molecular Immunology, 2011,49(1-2):84-96
（18）Zongxi Han, Chuyang Sun, Baolong Yan, Xiaonan Zhang, Yu Wang, Chengren Li, Qingxia Zhang, Yazhen Ma, Yuhao Shao, Qiaoran Liu, Xiangang Kong, Shengwang Liu*, A 15-year analysis of molecular epidemiology of avian infectious bronchitis coronavirus in China, Infection, Genetics and Evolution, 2011,11(1):190-200
专著：
兽医免疫学，中国农业出版社，2012-09-01 出版
兽医微生物，中国农业出版社， 2013-12-30  出版
现代动物病毒学，中国农业出版社， 2014-12-24出版  

 近五年授权的专利等情况
(1) 刘胜旺，孔宪刚，韩宗玺，邵昱昊，李慧昕，鸡传染性支气管炎病毒弱毒疫苗株及其应用，2011.03.23，中国，ZL8.5
(2）刘胜旺，韩宗玺，邵昱昊，刘晓丽，孔宪刚，鸡传染性支气管炎冷适应致弱疫苗株及其应用，2013.03.20，中国，ZL1.0
(3）刘胜旺，韩宗玺，邵昱昊，孔宪刚，鸡传染性支气管炎病毒疫苗株及其在制备灭活疫苗中的应用，2015.12.02，中国，ZL2.X
（4）刘胜旺，李慧昕，韩宗玺，孔宪刚，表达增强型绿色荧光蛋白基因的鸭瘟病毒重组疫苗株及其构建方法和应用，2014.07.14，中国，ZL8.3
(5) 刘胜旺，李慧昕，韩宗玺，孔宪刚,表达增强型绿色荧光蛋白基因的鸭瘟病毒重组疫苗株rDEVTK-EGFP及其构建方法和应用, 2014.09.18，中国，ZL7.6
(6) 刘胜旺，张宇，韩宗玺，一种鸡传染性支气管炎间接ELISA抗体检测试剂盒, 2015.08.21，中国，ZL4.7


 其他获奖及荣誉称号
中国农业科学院二级岗位杰出人才；
中国农业科学院哈尔滨兽医研究所禽呼吸道病研究团队首席科学家；
现代农业蛋鸡产业技术体系岗位科学家；
中国畜牧兽医学会禽病学分会理事；
黑龙江省畜牧兽医学会理事；
中国畜牧兽医学会兽医公共卫生学分会理事；
中国畜牧兽医学会信息技术分会理事；
第一届全国动物防疫专家委员会委员；
中国动物传染病学报编委会委员；
中国农业科学院哈尔滨兽医研究所学术委员会和高级职称评定委员会委员；
国家自然基金委的同行评议专家。