王加强
性 别： 男 出生年月： 1987-08-06
职 称： 教授 工作单位： 东北农业大学
招生学科1： 发育生物学 招生学科2：
办公电话： ** E-mail： wangjiaqiang@neau.edu.cn

 开设研究生课程情况
课程编号 课程名称 课程级别 学时
 近五年主持科研项目概况
(1) 国家自然科学基金委员会, **, 大鼠-小鼠异种杂合二倍体胚胎干细胞中异源基因组的互作模式的研究, 2020-01 至2024-12, 580000 RMB, 在研, 主持
(2) 中国博士后基金, 2017T100107, LincGET参与小鼠第一次细胞命运决定的研究, 2017-06 至2019-02, 150000 RMB, 已结题, 主持 (3) 中国博士后基金, 2017M610990, LincGET参与小鼠第一次细胞命运决定的研究, 2017-05 至2019-02, 50000 RMB, 已结题, 主持

 

 近五年项目获奖概况


 近五年代表性著作、论文
1. Jiaqiang Wang^#, Leyun Wang^#, Guihai Feng^#, Yukai Wang^#, Yufei Li, Xin Li, Chao Liu, Guanyi Jiao, Cheng Huang, Junchao Shi, Tong Zhou, Qi Chen, Zhonghua Liu, Wei Li*, Qi Zhou*, Asymmetric Expression of LincGET Biases Cell Fate in Two-Cell Mouse Embryos, Cell, 2018, 175(7): 1887-1901 e1818. (IF=36.216)
2. Jiaqiang Wang^#, Xin Li^#, Leyun Wang^#, Jingyu Li^#, Yanhua Zhao, Gerelchimeg Bou, Yufei Li, Guanyi Jiao, Xinghui Shen, Renyue Wei, Shichao Liu, Bingteng Xie, Lei Lei, Wei Li, Qi Zhou*, Zhonghua Liu*, A novel long intergenic noncoding RNA indispensable for the cleavage of mouse two-cell embryos, EMBO Rep, 2016, 17(10): 1452-1470. (IF=8.749)
3. Xin Li^#, Xiaolong Cui^#, Jiaqiang Wang^#, Yukai Wang, Yufei Li, Leyun Wang, Haifeng Wan, Tianda Li, Guihai Feng, Ling Shuai, Zhikun Li, Qi Gu, Jie Hao, Liu Wang, Xiaoyang Zhao, Zhonghua Liu, Xiujie Wang, Wei Li*, Qi Zhou*, Generation and Application of Mouse-Rat Allodiploid Embryonic Stem Cells, Cell, 2016, 164(1-2): 279-292. (IF=36.216)
4. Jiaqiang Wang, Qi Zhou, Derivation and application of pluripotent stem cells for regenerative medicine, Sci China Life Sci, 2016, 59(6): 576-583. (IF=3.583)
5. Jiaqiang Wang^#, Xin Li^#, Yanhua Zhao, Jingyu Li, Qi Zhou*, Zhonghua Liu*, Generation of cell-type-specific gene mutations by expressing the sgRNA of the CRISPR system from the RNA polymerase II promoters, Protein Cell, 2015, 6(9): 689-692. (IF=7.575)
6. Xin Li^#, Jiaqiang Wang^#, Leyun Wang^#, Haifeng Wan, Yufei Li, Tianda Li, Yukai Wang, Ling Shuai, Yihuan Mao, Xiaolong Cui, Liu Wang, Zhonghua Liu, Wei Li*, Qi Zhou*, Co-participation of paternal and maternal genomes before the blastocyst stage is not required for full-term development of mouse embryos, J Mol Cell Biol, 2015, 7(5): 486-488. (IF=5.595)
7. Jing Li, Chenxin Wang, Guihai Feng, Linlin Zhang, Guilai Chen, Hao Sun, Jiaqiang Wang, Ying Zhang*, Qi Zhou*, Wei Li*, Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing, Cell Prolif, 2019: e12724. (IF=5.039)
8. Yufei Li^#, Leyun Wang^#, Linlin Zhang^#, Zhengquan He^#, Guihai Feng, Hao Sun, Jiaqiang Wang, Zhikun Li, Chao Liu, Jiabao Han, Junjie Mao, Pengcheng Li, Xuewei Yuan, Liyuan Jiang, Ying Zhang*, Qi Zhou*, Wei Li*, Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I, J Cell Biol, 2019. (IF=8.784)
9. Weiqi Zhang^#, Haifeng Wan^#, Guihai Feng^#, Jing Qu^#, Jiaqiang Wang, Yaobin Jing, Ruotong Ren, Zunpeng Liu, Linlin Zhang, Zhiguo Chen, Shuyan Wang, Yong Zhao, Zhaoxia Wang, Yun Yuan, Qi Zhou, Wei Li*, Guanghui Liu*, Baoyang Hu*, SIRT6 deficiency results in developmental retardation in cynomolgus monkeys, Nature, 2018, 560(7720): 661-665. (IF=41.577)
10. Yanshuang Mu, Mingxia Jiao, Yanhua Zhao, Jiawei Lv, Jiaqiang Wang, J. Hao, X. Zhang, Qingran Kong, Zhonghua Liu*, A method for tracing exogenous DNA uptake in live spermatozoa and embryos, Pol J Vet Sci, 2018, 21(1): 193-202. (IF=0.802)
11. Leyun Wang^#, Fei Teng^#, Xuewei Yuan^#, Chao Liu^#, Jiaqiang Wang, Yufei Li, Tongtong Cui, Tianda Li, Zhonghua Liu, Qi Zhou*, Overexpression of Stella improves the efficiency of nuclear transfer reprogramming, J Genet Genomics, 2017, 44(7): 363-366. (IF=4.066)
12. Tianda Li^#, Guihai Feng^#, Yufei Li^#, Mei Wang^#, Junjie Mao, Jiaqiang Wang, Xin Li, Xuepeng Wang, Bin Qu, Leyun Wang, Xinxin Zhang, Haifeng Wan, Tongtong Cui, Cong Wan, Lei Liu, Xiaoyang Zhao, Baoyang Hu, Wei Li, Qi Zhou*, Rat embryonic stem cells produce fertile offspring through tetraploid complementation, Proc Natl Acad Sci U S A, 2017, 114(45): 11974-11979. (IF=9.504)
13. Tao Chen, Meng Sun, Jiaqiang Wang, Jinjin Cui, Zhonghua Liu, Bo Yu*, A novel swine model for evaluation of dyslipidemia and atherosclerosis induced by human CETP overexpression, Lipids Health Dis, 2017, 16(1): 169. (IF=2.651)
14. Gerelchimeg Bou, Shichao Liu, Jia Guo, Yueming Zhao, Mingju Sun, Binghua Xue, Jiaqiang Wang, Yanchang Wei, Qingran Kong, Zhonghua Liu*, Cdx2 represses Oct4 function via inducing its proteasome-dependent degradation in early porcine embryos, Dev Biol, 2016, 410(1): 36-44. (IF=2.936)
15. Ruizhen Sun, Lei Lei, Shichao Liu, Binghua Xue, Jianyu Wang, Jiaqiang Wang, Jingling Shen, Lian Duan, Xinghui Shen, Yimei Cong, Yanli Gu, Kui Hu, Lianhong Jin, Zhonghua Liu*, Morphological changes and germ layer formation in the porcine embryos from days 7-13 of development, Zygote, 2015, 23(2): 266-276. (IF=1.278)
16. Bingteng Xie, Jianyu Wang, Shichao Liu, Jiaqiang Wang, Binghua Xue, Jingyu Li, Renyue Wei, Yanhua Zhao, Zhonghua Liu*, Positive correlation between the efficiency of induced pluripotent stem cells and the development rate of nuclear transfer embryos when the same porcine embryonic fibroblast lines are used as donor cells, Cell Reprogram, 2014, 16(3): 206-214. (IF=1.453)
17. Jingyu Li, Yanjun Huan, Bingteng Xie, Jiaqiang Wang, Yanhua Zhao, Mingxia Jiao, Tianqing Huang, Qingran Kong, Zhonghua Liu*, Identification and characterization of an oocyte factor required for sperm decondensation in pig, Reproduction, 2014, 148(4): 367-375. (IF=3.125)
18. Qingran Kong, Tang Hai, Jing Ma, Tianqing Huang, Dandan Jiang, Bingteng Xie, Meiling Wu, Jiaqiang Wang, Yuran Song, Ying Wang, Yilong He, Jialu Sun, Kui Hu, Runfa Guo, Liu Wang, Qi Zhou, Yanshuang Mu, Zhonghua Liu*, Rosa26 locus supports tissue-specific promoter driving transgene expression specifically in pig, PLoS One, 2014, 9(9): e107945. (IF=2.776)
19. Yimei Cong, Jing Ma, Ruizhen Sun, Jianyu Wang, Binghua Xue, Jiaqiang Wang, Bingteng Xie, Juan Wang, Kui Hu, Zhonghua Liu*, Derivation of putative porcine embryonic germ cells and analysis of their multi-lineage differentiation potential, J Genet Genomics, 2013, 40(9): 453-464. (IF=4.066)
20. Tao Chen, Jiaqiang Wang, Binghua Xue, Qingran Kong, Zhonghua Liu, Bo Yu*, Identification and characterization of a novel porcine endothelial cell-specific Tie1 promoter, Xenotransplantation, 2013, 20(6): 438-448. (IF=3.789)


 近五年授权的专利等情况


 其他获奖及荣誉称号