侯晓明
性 别: 男 出生年月: 1979-05-05
职 称: 教授 工作单位: 生命科学学院
招生学科1: 细胞生物学 招生学科2:
办公电话: E-mail: xiaominghou@126.com
开设研究生课程情况
课程编号 课程名称 课程级别 学时
209338 功能基因分析技术 研究生 32
209215 细胞及组织学技术 研究生 12
近五年主持科研项目概况
(1)东北农业大学“学术骨干”项目:CIDEC对奶牛乳脂合成的调控作用研究,2017.10-2019.10,10万元,主持
(2)国家自然科学基金-面上项目:CIDEC基因调控奶牛乳脂合成的机理研究,2017.1-2020.12,60万元,主持
(3)国家自然科学基金-青年项目:Syk基因在奶牛乳腺泌乳过程中的功能研究,2013.1-2015.12,21万元,主持
(4)黑龙江省博士后科研启动金:CIDEC基因在奶牛乳脂合成过程中的调控机制研究,2017.1-2018.12,5万元,主持
(5)黑龙江博士后资助项目:Syk基因调控奶牛乳腺泌乳功能的机制研究,2015.1-2016.12,7万元,主持
(6)黑龙江省自然科学基金:Nobox基因在猪卵母细胞发育中的作用研究,2013.1-2015.12,5万元,主持
近五年项目获奖概况
科研简介:主要从事哺乳动物乳腺泌乳机制的研究,采用各种细胞生物学及分子生物学技术研究乳腺细胞中调控乳成分合成及分泌的分子机制。主要涉及基因功能的鉴定、基因表达的调控研究、细胞内的物质转运研究、细胞内的物质合成研究等。欢迎有此研究兴趣的同学报考,请有兴趣的同学在初试成绩公布之后发送一个带照片的简历到我的邮箱,主要标明初试成绩、四六级通过情况、本科阶段所学专业和成绩排名、本科的毕业设计情况等信息。
近五年代表性著作、论文
专著:
《奶牛乳腺发育与泌乳生物学》,参编,科学出版社,900千字,2014.01
研究论文:
(1)Song S, Jiang M, Zhou J, Zhao F, Hou X*, Lin Y*. Nutrigenomic Role of Acetate and β-Hydroxybutyrate in Bovine Mammary Epithelial Cells. DNA Cell Biol. 2020 Jan 2. [Epub ahead of print]
(2)Wang B, Shi L, Men J, Li Q, Hou X, Wang C, Zhao F*. Controlled synchronization of prolactin/STAT5 and AKT1/mTOR in bovine mammary epithelial cells. In Vitro Cell Dev Biol Anim. 2020 Feb 20. [Epub ahead of print]
(3)Wang B, Men J, Wang C, Hou X, Zhao F*. Laminin-dependent integrin β1 signaling regulates milk protein synthesis via prolactin/STAT5 pathway in bovine mammary epithelial cells. Biochem Biophys Res Commun. 2020 Jan 24. [Epub ahead of print]
(4)Lin Y, Lv H, Jiang M, Zhou J, Song S, Hou X*. Functional analysis of the dairy cow mammary transcriptome between early lactation and mid-dry period. J Dairy Res. 2019, 86(1):63-67.
(5)Lin Y, Duan X, Lv H, Yang Y, Liu Y, Gao X, Hou X*. The effects of L-type amino acid transporter 1 on milk protein synthesis in mammary glands of dairy cows. J Dairy Sci. 2018, 101(2): 1687-1696.
(6)Duan X, Lin Y, Lv H, Yang Y, Jiao H, Hou X*. Methionine Induces LAT1 Expression in Dairy Cow Mammary Gland by Activating the mTORC1 Signaling Pathway. DNA Cell Biol. 2017, 36(12):1126-1133.
(7)Yang Y, Lin Y, Duan X, Lv H, Xing W, Li Q, Gao X, Hou X*. The effects of cell death-inducing DNA fragmentation factor-α-like effector C on milk lipid synthesis in mammary glands of dairy cows. J Dairy Sci. 2017, 100(5):4014-4024.
(8)邢伟楠,段晓宇,杨洋,侯晓明,林叶*. L型氨基酸转运载体1对奶牛乳腺中β-酪蛋白表达的影响. 中国畜牧兽医. 2016,43(10):2553-2559.
(9)Lin Y, Sun X, Hou X, Qu B, Gao X, Li Q*. Effects of glucose on lactose synthesis in mammary epithelial cells from dairy cow. BMC Vet Res. 2016 May 26;12(1):81.
(10)Hou X, Hu H, Lin Y, Qu B, Gao X, Li Q*. The effect of GRK2 on lactation and on proliferation of mammary epithelial cells from dairy cows, J Dairy Sci, 2016, 99(7):5828-5836.
(11)Hou X, Lin L, Xing W, Yang Y, Duan X, Li Q, Gao X, Lin Y*. Spleen tyrosine kinase regulates mammary epithelial cell proliferation in mammary glands of dairy cows, J Dairy Sci, 2016, 99(5): 3868-3868.
(12)Lin Y, Hou X, Shen WJ, Hanssen R, Khor VK, Cortez Y, Roseman AN, Azhar S, Kraemer FB*. SNARE-Mediated Cholesterol Movement to Mitochondria Supports Steroidogenesis in Rodent Cells. Mol Endocrinol. 2016, 30(2): 234-247.
(13)杨洋,林叶,邢伟楠;段晓宇,倪华,侯晓明*. 母源基因在猪卵母细胞成熟及胚胎发育中的作用. 畜牧与兽医,2015, 47(11):124-126.
(14)杨洋,张凯鑫,林叶,林琳,邢伟楠,倪华,侯晓明*. 新生儿卵巢同源盒基因在猪卵巢中的表达研究. 中国畜牧兽医,2015, 42(10): 2701-2706.
(15)Zhang H, Li Y, Hu J, Shen WJ, Singh M, Hou X, Bittner A, Bittner S, Cortez Y, Tabassum J, Kraemer FB, Azhar S*. Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis. PLoS One, 2015, 10(9):e**.
(16)Cui Y, Liu Z, Sun X, Hou X, Qu B, Zhao F, Gao X, Sun Z, Li Q*. Thyroid hormone responsive protein spot 14 enhances lipogenesis in bovine mammary epithelial cells. In Vitro Cell Dev Biol Anim. 2015; 51(6):586-594.
(17)林琳,范会全,邢伟楠,杨洋,侯晓明,张常顺,林叶*. 脾源性酪氨酸激酶基因在奶牛乳腺中的表达研究. 中国畜牧兽医,2015, 42(5):1240-1244.
(18)Liang M, Hou X, Qu B, Zhang N, Li N, Cui Y, Li Q, Gao X*. Functional analysis of FABP3 in the milk fat synthesis signaling pathway of dairy cow mammary epithelial cells. In Vitro Cell Dev Biol Anim. 2014; 50(9):865-873.
(19)Wang Z, Hou X, Qu B, Wang J, Gao X, Li Q*. Pten regulates development and lactation in the mammary glands of dairy cows. PLoS One, 2014, 9(7):e102118.
近五年授权的专利等情况
其他获奖及荣誉称号
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