尹杰超
性 别： 女 出生年月： 1980-02-06
职 称： 副教授 工作单位： 东北农业大学生命科学学院
招生学科1： 生化与分子生物学 招生学科2：
办公电话： E-mail： yinjiechao@126.com

 开设研究生课程情况
课程编号 课程名称 课程级别 学时
 近五年主持科研项目概况
“十三五”国家重点研发计划《治疗和预防鸡传染性法氏囊病的鸡源重组抗体开发》（2017YFD**） 2017-2020年 40万

 近五年项目获奖概况


 近五年代表性著作、论文
文章：
1. FGF21 attenuates pulmonary fibrogenesis through ameliorating oxidative stress in vivo and in vitro. Zhang S, Yu D, Wang M, Huang T, Wu H, Zhang Y, Zhang T, Wang W, Yin J, Ren G, Li D. Biomed Pharmacother. 2018 Jul; 103: 1516-1525. doi: Select item **
2. A recombinant avian antibody against VP2 of infectious bursal disease virus protects chicken from viral infection. Zhang Y, Yin J, Li T, Zhou B, Xu P, Che R, Liu Y, Cao H, Ye X, Yang Y, Qi X, Zheng S, Ding G, Ren G, Yang H, Wang X, Li D. Res Vet Sci. 2017 Oct;114:194-201. doi: 10.1016/j.rvsc.2017.04.003.
3. Recombinant Newcastle disease virus expressing human TRAIL as a potential candidate for hepatoma therapy. Wu Y, He J, Geng J, An Y, Ye X, Yan S, Yu Q, Yin J, Zhang Z, Li D. Eur J Pharmacol. 2017 May 5;802:85-92. doi: 10.1016/j.ejphar.2017.02.042.
4.Recombinant NDV expressing cytokines or fliC confers a quick immune response against NDV challenge and resistance to maternal antibody.Zhang T, Liu Y, Wang H, Zhang X, Zhu S, Xu P, Yin J, Ren G,Liu J, Li D. Vet Microbiol. 2016 Nov 30; 196:107-117. doi: 10.1016/j.vetmic.2016.10.008.
5. Screening scFv antibodies against infectious bursal disease virus by co-expression of antigen and antibody in the bacteria display system. Guo X, Cao H, Wang Y, Liu Y, Chen Y, Wang N, Jiang S, Zhang S, Wu Q, Li T, Zhang Y, Zhou B, Yin J, Li D, Ren G. Vet Immunol Immunopathol. 2016 Nov 1; 180: 45-52. doi: 10.1016/j.vetimm.2016.09.004.
6.Recombinant Newcastle disease virus expressing P53 demonstrates promising antitumor efficiency in hepatoma model.An Y, Liu T, He J, Wu H, Chen R, Liu Y, Wu Y, Bai Y, Guo X, Zheng Q, Liu C, Yin J, Li D, Ren G.J Biomed Sci. 2016 Jul 28;23(1):55. doi: 10.1186/s12929-016-0273-0.
7.Selection of affinity-improved neutralizing human scFv against HBV PreS1 from CDR3 VH/VL mutant library.Chen Y, Bai Y, Guo X, Wang W, Zheng Q, Wang F, Sun D, Li D, Ren G, Yin J.Biologicals. 2016 Jul;44(4):271-275. doi: 10.1016/j.biologicals.2016.05.003. （通讯作者）
8.Recombinant Newcastle disease virus (NDV/Anh-IL-2) expressing human IL-2 as a potential candidate for suppresses growth of hepatoma therapy.Wu Y, He J, An Y, Wang X, Liu Y, Yan S, Ye X, Qi J, Zhu S, Yu Q, Yin J, Li D, Wang W. J Pharmacol Sci. 2016 Sep;132(1):24-30. doi: 10.1016/j.jphs.2016.03.012.
9. Newcastle disease virus chimeras expressing the Hemagglutinin- Neuraminidase protein of mesogenic strain exhibits an enhanced anti-hepatoma efficacy. He J, Pan Z, Tian G, Liu X, Liu Y, Guo X, An Y, Song L, Wu H, Cao H, Yu D, Che R, Xu P, Rasoul LM, Li D, Yin J.Virus Res. 2016 Aug 2; 221:23-9. doi: 10.1016/j.virusres.2016.04.023. （通讯作者）
10. Recombinant Newcastle Disease Virus Encoding IL-12 and/or IL-2 as Potential Candidate for Hepatoma Carcinoma Therapy. Ren G, Tian G, Liu Y, He J, Gao X, Yu Y, Liu X, Zhang X, Sun T, Liu S, Yin J, Li D. Technol Cancer Res Treat. 2016 Oct; 15(5):NP83-94. doi: 10.1177/**01521.
11.Recombinant Newcastle Disease virus Expressing IL15 Demonstrates Promising Antitumor Efficiency in Melanoma Model.Niu Z, Bai F, Sun T, Tian H, Yu D, Yin J, Li S, Li T, Cao H, Yu Q, Wu Y, Ren G, Li D. Technol Cancer Res Treat. 2015 Oct;14(5):607-15. doi: 10.7785/tcrt.2012.500414.

论著：
普通高等教育农业部“十二五”规划教材《生物技术制药》, 中国农业出版社, 2018年1月，主编：李德山，参编尹杰超等。


 近五年授权的专利等情况
已授权：
一种表达鸡IBDV抗体的重组NDV及其在制备双价疫苗中的应用 - 9.4

实审阶段：
一种制备B区缺失的成熟人凝血因子Ⅷ的方法 - 1.X
两种scFv抗体、其编码基因及其在制备治疗或预防鸡传染性法氏囊病制剂中的应用 - 7.6
三种scFv抗体、其编码基因及其在制备治疗或预防O型口蹄疫病制剂中的应用 - 1.6



 其他获奖及荣誉称号