性 别: 男 出生年月: 1963-06-01
职 称: 教授 工作单位: 动物科学技术学院学院
招生学科1: 动物遗传育种与繁殖 招生学科2:
办公电话: E-mail: lihui@neau.edu.cn
开设研究生课程情况
课程编号 课程名称 课程级别 学时
5.510 现代养禽 硕士课 36
5.501 动物遗传育种硕士研究生班讨论 硕士课 72
5.005 家禽育种 博士课 56
5.003 动物遗传育种博士研究生班讨论 博士课 72
近五年主持科研项目概况
1.国家自然科学基金重点项目
项目名称:鸡脂肪组织生长的分子遗传学基础(编号:**),130万,本人为项目主持人,2005-2008。
2.黑龙江省自然科学基金重点项目
项目名称:鸡脂肪细胞分化转录因子基因的功能研究(编号:ZJN0604-01),10万,本人为项目主持人,2007-2009。
完成人排序:第一
3.国家973项目
项目名称:猪、鸡重要经济性状遗传的分子机制(No.2006CB102100)。课题名称:重要复杂性状的比较基因组(No.2006CB102105),课题总经费383万元,本人经费96万元,本人为课题第二主持人,2006-2010。
4.国家863重大项目
项目名称:主要动植物功能基因组研究。课题名称:家鸡重要经济性状功能基因组研究(2006AA10A120),课题总经费565万元,本人经费115万元,本人为课题副主持人, 2006-2010。
5.国家转基因生物新品种培育重大专项课题
课题名称:高通量基因克隆技术体系的研究(2008ZX08009-002);任务名称:影响猪、牛、羊生长与肉质等性状的功能基因的高通量克隆鉴定技术;子任务名称:羊毛品质性状关键基因的高通量筛选和克隆,76万元,本人为子任务主持人,2008-2011。
6.国家现代农业产业技术体系建设项目
项目名称:国家肉鸡产业技术体系(No.CARS-42),210万元,本人为岗位专家,2008-2010。
7.国家高技术研究发展计划(863)项目子课题
项目名称:主要动植物功能基因组研究;课题名称:优质速长型白羽黄鸡全基因组选择育种研究(编号:2010AA10A102),21万元,本人为课题子任务负责人,2010-2011。
8.黑龙江省高等学校科技创新团队建设计划项目
团队名称:家禽遗传育种创新团队;项目名称:鸡生长和体组成性状的功能基因组,200万元,本人为团队负责人和项目主持人,2010-2013。
9.国家现代农业产业技术体系建设项目
项目名称:国家肉鸡产业技术体系(No.CARS-42),350万元,本人为岗位专家,2011-2015。
10.国家高技术研究发展计划(863)项目
项目名称:鸡重要经济性状的功能基因组学研究(2013AA102501),1028万,本人为课题主持人,2013-2017。
近五年项目获奖概况
1.2010,“鸡脂肪组织生长发育的分子遗传学基础”, 2010年黑龙江省高校科学技术一等奖,排名第一。证书编号:2010-018-1
2.2010,“畜禽良种资源综合利用支撑技术的研究”,2010年黑龙江省科技进步二等奖,排名第三。证书编号:2010-084-03
3.2013,“低脂肉鸡种质资源创新及脂肪发育分子遗传学研究”,2013年黑龙江省科学技术奖一等奖,排名第一。证书号2013-008-04
近五年代表性著作、论文
208. Ning Ding, Yuan Gao, Ning Wang, Hui Li. Functional analysis of the chicken PPARγ gene 5′-flanking region and C/EBPα-mediated gene regulation. Comparative Biochemistry and Physiology, Part B, 2011, 158, 297-303.
210. Jing Yao, Yuxiang Wang, Weishi Wang, Ning Wang, and Hui Li. Solexa sequencing analysis of chicken pre-adipocyte microRNAs. Biosci. Biotechnol. Biochem., 2011, 75(1): 54-61.
216. H. Zhang, S. H. Liu, Q. Zhang, Y. D. Zhang, S. Z. Wang, Q. G. Wang, Y. X. Wang, Z. Q. Tang & H. Li. Fine-mapping of quantitative trait loci for body weight and bone traits and positional cloning of the RB1 gene in chicken. J. Anim. Breed. Genet. 2011,128: 366–375.
217. H. Shi, Q. Zhang, Y. Wang, P. Yang, Q. Wang, and H. Li. Chicken adipocyte fatty acid-binding protein knockdown affects expression of peroxisome proliferator-activated receptor γ gene during oleate-induced adipocyte differentiation. Poultry Science, 2011, 90:1037-1044.
220.L. Guo, B. Sun, Z. Shang, L. Leng, Y. Wang, N. Wang, and H. Li. Comparison of adipose tissue cellularity in chicken lines divergently selected for fatness. Poultry Science, 2011, 90: 2024-2034.
226. S.Z. Wang, X.X. Hu, Z.P. Wang, X.C. Li, Q.G. Wang, Y.X. Wang, Z.Q. Tang and H. Li. Quantitative trait loci associated with body weight and abdominal fat traits on chicken chromosomes 3, 5 and 7. Genetics and Molecular Research, 2012, 11 (2): 956-965.
230. Hui Zhang, Xiaoxiang Hu, Zhipeng Wang, Yuandan Zhang, Shouzhi Wang, Ning Wang, Li Ma, Li Leng, Shengwen Wang, Qigui Wang, Yuxiang Wang, Zhiquan Tang, Ning Li, Yang Da, Hui Li. Selection Signature Analysis Implicates the PC1/PCSK1 Region for Chicken Abdominal Fat Content. PLoS ONE, 2012 7(7): e40736.
238. Hui Zhang, Shou-Zhi Wang, Zhi-Peng Wang, Yang Da, Ning Wang, Xiao-Xiang Hu, Yuan-Dan Zhang, Yu-Xiang Wang, Li Leng, Zhi-Quan Tang and Hui Li. A genome-wide scan of selective sweeps in two broiler chicken lines divergently selected for abdominal fat content. BMC Genomics, 2012,13:704.
254. Zhiwei Zhang, Haixia Wang, Yingning Sun, Hui Li, and Ning Wang. Klf7 modulates the differentiation and proliferation of chicken preadipocyte. Acta Biochim Biophys Sin 2013, 45: 280–288.(王宁和李辉为通讯作者)
258. Zhi-Wei ZHANG, Zhi-Peng WANG, Kun ZHANG, Ning WANG and Hui LI. Cloning, tissue expression and polymorphisms of chicken Krüppel-like factor 7 gene. Animal Science Journal, 2013, 84: 535–542.(李辉为通讯作者)
259. Q. Zhang, H. Shi, W. Liu, Y. Wang, Q. Wang and H. Li. Differential expression of L-FABP and L-BABP between fat and lean chickens.Genet. Mol. Res., 2013, 12 (4): 4192-4206.(李辉和王启贵为通讯作者)
260. Yufang Zhao, Enguang Rong, Shouzhi Wang, Hui Zhang, Li Leng, Yuxiang Wang, Qigui Wang and Hui Li. Identification of SNPs of the L-BABP and L-FABP and their Association with Growth and Body Composition Traits in Chicken. J. Poult. Sci., 2013, 50: 300-310. (李辉、王启贵为通讯作者)
262. Fangge Li, Guo Hu, Hui Zhang, Shouzhi Wang, Zhipeng Wang and Hui Li. Epistatic Effects on Abdominal Fat Content in Chickens: Results from a Genome-Wide SNP-SNP Interaction Analysis. PLoS ONE, 2013, 8(12): e81520. (李辉为通讯作者)
268. Zhouchun SHANG, Lin GUO, Ning WANG, Hui SHI, Yuxiang WANG and Hui LI. Oleate promotes differentiation of chicken primary preadipocytes in vitro. Biosci.Rep., 2014, 34(1):51-57.(李辉为通讯作者)
270. S. J. Liu, J. L. Li and H. Li. A diagnostic method for gander selection in Zi geese(Anser cygnoides L.) and Rhin geese(Anser anser L.) using massage reaction and semen quality. Animal Production Science, 2014, 54, 569–573.(李辉为通讯作者)
271. Hui-Zhang, Zhi-Qiang Du, Jia-Qiang Dong, Hai-Xia Wang, Hong-Yan Shi, Ning Wang, Shou-Zhi Wang and Hui Li. Detection of genome-wide copy number variations in two chicken lines divergently selected for abdominal fat content. BMC Genomics, 2014, 15(1):1-12.(李辉为通讯作者)
272. Zhi-Wei Zhang, Chun-Yan Wu, Hui Li and Ning Wang. Expression and functional analyses of Krüppel-like factor 3 in chicken adipose tissue. Bioscience, Biotechnology, and Biochemistry, 2014, 78(4): 614–623.(王宁、李辉为通讯作者)
273. Z. W. Zhang, E. G. Rong, M. X. Shi, C. Y. Wu, B. Sun, Y. X. Wang,
274. Zhipeng Wang, Hui Zhang, Hua Yang, Shouzhi Wang, Enguang Rong, Wenyu Pei, Hui Li, Ning Wang. Genome-Wide Association Study for Wool Production Traits in a Chinese Merino Sheep Population. PLoS ONE, 2014, 9(9): e107101. (王宁、李辉为通讯作者)
275. Q. He, S.Z. Wang, L. Leng, W. Na, Q.G. Wang, and H. Li. Differentially expressed genes in the liver of lean and fat chickens. Genetics and Molecular Research, 2014, 13 (4): 10823-10828.(李辉、王启贵为通讯作者)
299. Gao GL, Na W, Wang YX, Zhang HF, Li H, Wang QG. Role of a liver fatty acid-binding protein gene in lipid metabolism in chicken hepatocytes. Genet Mol Res., 2015, 14(2): 4847-4857.
300. Wang QG, Zhang HF, Wang SZ, Gao GL, Leng L, Na W, Li H. Microarray analysis of differentially expressed genes in the liver between Bai'er layers and broilers. Genet Mol Res., 2015, 14(1): 2885-2889.
301. Wang W, Du ZQ, Cheng B, Wang Y, Yao J, Li Y, Cao Z, Luan P, Wang N, Li H. Expression profiling of preadipocyte microRNAs by deep sequencing on chicken lines divergently selected for abdominal fatness. PLoS One, 2015, 10(2): e**.
302. Dong J-Q, Zhang Hui, Jiang X-F, Wang S-Z, Leng L, Cao Z-P, Li Y-M, Luan P, Li H. Comparison of serum biochemical parameters between two broiler chicken lines divergently selected for abdominal fat content. J. Anim. Sci., 2015, 93(7):3278-86.
303. Gao Y, Sun Y, Duan K, Shi H, Wang S, Li H, Wang N. CpG site DNA methylation of the CCAAT/enhancer-binding protein, alpha promoter in chicken lines divergently selected for fatness. Anim Genet. 2015 Aug;46(4):410-7.
304. Liang MJ, Wang ZP, Xu L, Leng L, Wang SZ, Luan P, Cao ZP, Li YM, Li H. Estimates of genetic parameters for liver fat traits in broiler lines divergently selected for abdominal fat. Genet Mol Res., 2015, 14(3):9646-54.
305. Jing PC,Wu X, Xu S, Zhang H, Li Y, Cao Z, Li H, Wang S. Differential expression of six genes and correlation with fatness traits in a unique broiler population. Saudi Journal of Biological Sciences, doi:10.1016/j.sjbs.2015.04.014.
307. Duan K, Sun Y, Zhang X, Zhang T, Zhang W, Zhang J, Wang G, Wang S, Leng L, Li H, Wang N. Identification and characterization of transcript variants of chicken peroxisome proliferator-activated receptor gamma. Poult Sci., 2015, 94(10):2516-27.
309. Xianwen Wu, Qi Zhang, Songsong Xu, Pengcheng Jin, Peng Luan, Yumao Li, Zhiping Cao, Li Leng, Yuxiang Wang, Shouzhi Wang. Differential expression of six chicken genes associated with fatness traits in a divergently selected broiler population. Mol Cell Probes, 2016, 30(1):1-5.
310. B.H. Cheng, L. Leng, M.Q. Wu, Q. Zhang, X.Y. Zhang, S.S. Xu, Z.P. Cao, Y.M. Li, P. Luan, H. Li. Expression analysis of bone morphogenetic protein 4 between fat and lean birds in adipose tissue and serum. Domestic Animal Endocrinology, 2016, 56:13–19.
近五年授权的专利等情况
李辉,田建伟;专利名称:一种用ACCα基因预示和鉴定鸡腹脂量的分子标记方法;专利申请日:2009年3月18日;专利权人:东北农业大学;发明专利申请号:2.8,2009;证书号:第875823号;专利号:ZL 2009 1 **.8;授权公告日:2011年12月7日。
其他获奖及荣誉称号
1.2008年被评为黑龙江省优秀中青年专家。
2.2008年被评为黑龙江省优秀共产党员。
3.2009年被评为黑龙江省教育系统教书育人、管理育人、服务育人先进工作者。
4.2010年被评为黑龙江省研究生优秀导师。
5.2011年度在以东北农业大学党委命名表彰的“先优”活动中,被评为科研先锋岗。
6.2011年被评为中国畜牧兽医学会先进工作者。
7.2012年被评为黑龙江省畜牧兽医行业领军人物。