刘忠华
性 别： 男 出生年月： 1972-10-01
职 称： 教授 工作单位： 生命科学学院
招生学科1： 发育生物学 招生学科2：
办公电话：E-mail： liu086@126.com

 开设研究生课程情况
课程编号 课程名称 课程级别 学时
生殖生物学 硕士课 72
发育生物学 博士课 54
发育生物学研究生班讨论 硕士课 36
 近五年主持科研项目概况
主持国家重大基础科学研究计划项目课题1项，作为骨干参加2项；
主持863子课题1项；
主持自然科学基金1项；
主持转基因育种重大专项子课题1项；


 近五年项目获奖概况
获得黑龙江省科技进步一等奖（自然科学类）一项

 近五年代表性著作、论文
1.    Cong Y, Ma J, Sun R, Wang J, Xue B, Wang J, Xie B, Wang J, Hu K, Liu Z. Derivation of putative porcine embryonic germ cells and analysis of their multi-lineage differentiation potential. J Genet Genomics. 2013 40(9):453-64.
2.    He Wenteng，Qingran Kong, Yongqian Shi, Bingteng Xie, Mingxia Jiao, Tianqing Huang, Shimeng Guo, Kui Hu, Zhonghua Liu. Generation and developmental characteristics of porcine tetraploid embryos and tetraploid/diploid chimeric embryos. Genomics Proteomics Bioinformatics. 2013 11:327-333
3.    Wang J, Gu Q, Hao J, Jia Y, Xue B, Jin H, Ma J, Wei R, Hai T, Kong Q, Bou G, Xia P, Zhou Q, Wang L, Liu Z. Tbx3 and Nr5α2 play important roles in pig pluripotent stem cells. Stem Cell Rev. 2013 9(5):700-8
4.    Zhi Yin, Qingran Kong, Zeping Zhao, MeiLing Wu, YanShuang Mu, Kui Hu and Zhonghua Liu. Position effect variegation and epigenetic modification of a transgene in a pig model. Genetics and Molecular Research 2012. 11 (1): 355-369
5.    Kui Hu, Qingran Kong, Zeping Zhao, Xinyu Lu, Biao Liu, Yutian Li, Hongbin Wang and Zhonghua Liu. Assessment of reproduction and growth performanceof offspring derived from somatic cell cloned pigs. Animal Science Journal 2012. 83(9):639-43. 2012.
6.    Yanchang Wei, Yanjun Huan, Yongqian Shi, Zhongfeng Liu, Gerelchimeg Bou, Yibo Luo, Li Zhang, Cairong Yang, Qingran Kong, Jiangtian Tian, Ping Xia, Qing-Yuan Sun, ZhongHua Liu.Unfaithful maintenance of methylation imprints due to loss of maternal nuclear Dnmt1 during somatic cell nuclear transfer  PLoS One. 2011,6(5):e20154
7.    Qingran Kong, Meiling Wu, Zhenkun Wang, Xinmiao Zhang, Yibo Luo, Xiangyu Liu, Yanshuang Mu, and Zhonghua Liu. Effect of Trichostatin A and 5-Aza-2'-deoxycytidine on transgene reactivation and epigenetic modification in transgenic pig fibroblast cells. Molecular and Cellular Biochemistry 2011, 355(1-2):157-65.
8.    Qingran Kong; Meiling Wu; Li Zhang; Feng Wang; Zhi Yin; Yanshuang Mu; zhonghua liu Transgene insertion affects transcription and epigenetic modification of flanking host sequence in transgenic pigs. Cellular and Molecular Biology. 2011, 57 Suppl:OL1505-12.
9.    Zhang Li，Luo Yibo ，Bou Gerelchimeg，Kong Qingran，Huan Yanjun，Zhu Jiang，Wang Jianyu，Li Hui，Wang Feng，Shi Yongqian，Wei Yanchang，Liu Zhonghua. Overexpression of nanog activate pluripotent genes in porcine fetal fibroblasts and nuclear transfer embryos. Anatomical Record 2011, 294( 11): 1809–1817
10.   Reizhen Sun, Lei Lei, Ling Cheng, Zhiyan Shan, Zhendong Wang, Jiaxin Zhang, Zhonghua Liu. Expression of GDF-9,BMP-15 and their receptors in mammalian ovary follicles.  J. Mol. His. 2010, 41:325-332
11.   Yanchang Wei, Jiang Zhu, Yanjun Huan, Zhongfeng Liu,Cairong Yang, Xinmiao Zhang, Yanshuang Mu, Ping Xia, Zhonghua Liu Aberrant expression and methylation status of putatively imprinted genes in placenta of cloned piglets. cellular Reprogrammming 2010, 12( 2):213-222
12.   Qingran Kong, Meiling Wu, Yanjun Huan, Li Zhang, Liu Hongtao, Gerelchimeg Bou, Yibo Luo, Yanshuang Mu, Zhonghua Liu. Transgene expression is associated with copy number and cytomegalovirus promoter methylation in transgenic pigs. PLoS One. 2009, 4(8):e6679.
13.   Qingran Kong, Meiling Wu, Jiang Zhu, Gerelchimeg B, Yanjun Huan, Zhi Yin,Yanshuang Mu, Zhonghua Liu Study on the copy number and integration site of transgenein transgenic pig  Progress in Biochemistry and Biophysics 2009, 36(12): 1617-25
14.   Gerelchimeg Bou, Liqing Liu, Zhong Zheng, Jiangtian Tian, Qingran Kong, Jun Song, Xuedong Wang, Zhonghua Liu. Effect of Chilling on Porcine Germinal Vesicle Stage Oocytes at the Subcellular Level 2009, Cryobiology 59(1):54-58

 近五年授权的专利等情况


 其他获奖及荣誉称号