基本信息
向文胜
性 别：男出生年月：1968-06-01
职 称：教授工作单位：生命科学学院
招生学科1：微生物学招生学科2：生物化学与分子生物学
办公电话：E-mail：xiangwensheng@neau.edu.cn

开设研究生课程情况
课程编号课程名称课程级别学时
11.503仪器分析硕士课88
9.591生物化工研究生班讨论硕士课36
近五年主持科研项目概况
(1) 国家杰出青年基金——微生物天然产物农药

(2) 973项目——勃利霉素化学成药性及作用机理研究

(3) 国家“十一五”支撑计划--新型抗寄生虫原料药的研制与应用

(4) 国家“十一五”支撑计划--驱虫类药物先导化合物及菌株的筛选技术研究

(5) 国家自然科学基金——S.avermitilis neau1069生物合成多拉菌素基因簇克隆和关键基因功能分析

(6) 国家自然科学基金——高选择性谷氨酸门控氯离子通道筛选体系研究与应用

(7) 国家自然科学基金——γ-氨基丁酸受体亲和筛选模型的构建和获得新配体方法的建立及应用

(8) 教育部“新世纪优秀人才”计划--冰城链霉菌全基因组测序及功能分析

(9) 黑龙江省首批“****后备人才”启动基金

(10) 黑龙江省杰出青年基金--冰城链霉菌生物合成米尔贝霉素基因簇及调控基因克隆与高产代谢工程菌的构建

近五年项目获奖概况
以第一完成人获省科技发明一等奖（2011年）、省自然科学二等奖（2007年）、省青年科技奖（2007年）各一项。

近五年代表性著作、论文
在Biotechnology Advances（IF 9.599）、Organic Letters（IF 6.142）等期刊发表SCI论文94篇，平均影响因子2.0，被美国布朗大学Cane院士等在PNAS、JACS（IF 9.9）、Nat Prod Rep（IF 9.79）、Chem Soc R（IF 28.76）、Microbiol Mol Biol R（IF 13.02）等他引。

代表性论文：

2014年，10篇，10篇通讯作者

1、 Ji Zhang, Ji-Dong Wang, Chong-Xi Liu, Jia-Hui Yuan, Xiang-Jing Wang & Wen-Sheng Xiang(*).A new prenylated indole derivative from endophytic actinobacteria Streptomyces sp. neau-D50, Nat Prod Res DOI10.1080/**.2013.871546 (SCI, IF1.031 in 2013)

2、 Tai Guo Liu, Xi Wang, Li Gao, Bo Liu, Wan Quan Chen, Wen Sheng Xiang(*). A FIASCO-based approach for detection and diagnosis of Puccinia graminis f.sp. tritici in China, Journal of Integrative Agriculture, in press

3、 Jiang L, Saavedra AN, Way G, Alanis J, Kung R, Li J, Xiang W(*), Liao J. Specific substrate recognition and thioester intermediate determinations in ubiquitin and SUMO conjugation cascades revealed by a high-sensitive FRET assay. Mol Biosyst. 2014 Jan 2 (SCI, IF3.35 in 2013)

4、 Zhang X, Zhang Y, Zhao J, Liu C, Wang S, Yang L, He H, Xiang W(*), Wang X. Nonomuraea fuscirosea sp. nov., a novel actinomycete isolated from the rhizosphere soil of rehmannia (Rehmannia glutinosa Libosch). Int J Syst Evol Microbiol. 2013 Dec 24. doi: 10.1099/ijs.0.057877-0 (SCI, IF2.112 in 2013)

5、 He H, Liu C, Zhao J, Li W, Pan T, Yang L, Wang X, Xiang W(*). Streptomyces zhaozhouensis sp. nov., a novel actinomycete isolated from candelabraaloe (Aloe arborescens Mill). Int J Syst Evol Microbiol. 2013 Dec 24. doi: 10.1099/ijs.0.056317-0 (SCI, IF2.112 in 2013)

6、 Xiang W, Yu C, Liu C, Zhao J, Yang L, Xie B, Li L, Hong K, Wang X. Micromonospora polyrhachis sp. nov., a novel actinomycete isolated from edible Chinese black ant (Polyrhachis vicina Roger). Int J Syst Evol Microbiol. 2013 doi: 10.1099/ijs.0.055863-0 (SCI, IF2.112 in 2013)

7、 Gao R, Liu C, Zhao J, Jia F, Yu C, Yang L, Wang X, Xiang W(*). Micromonospora jinlongensis sp. nov., isolated from muddy soil in China and emended description of the genus Micromonospora, Antonie Van Leeuwenhoek,2014,105(2):307-15 (SCI, IF 2.072 in 2013)

8、 Xinhui Zhang, Chongxi Liu, Yuejing Zhang, Haiyan Wang, Shurui Wang, Chuang Li, Xiangjing Wang, Wensheng Xiang(*). Streptosporangium shengliensis sp. nov., a novel actinomycete isolated a lake sediment. Anton Leeuw Int J G, 2014, 105(1):237-43, DOI: 10.1007/s10482-013-0070-7 (SCI, IF2.072 in 2013)

9、 Shurui Wang, Chongxi Liu, Yuejing Zhang, Junwei Zhao, Xinhui Zhang, Lingyu Yang, Xiangjing Wang, Wensheng Xiang(*). Nonomuraea guangzhouensis sp. nov., and Nonomuraea harbinensis sp. nov., two novel actinomycetes isolated from soil. Anton Leeuw Int J G, 2014,105(1):109-18, DOI: 10.1007/s10482-013-0058-3 (SCI, IF2.072 in 2013)

10、 Yuejing Zhang, Junwei Zhao, Chongxi Liu, Yue Shen, Feiyu Jia, Xiangjing Wang, Wensheng Xiang(*). Nonomuraea shaanxiensis sp. nov., a novel actinomycete isolated from a soil sample. Anton Leeuw Int J G, 2014, 105(1):57-64. DOI 10.1007/s10482-013-0052 (SCI, IF2.072 in 2013)
2013年，21篇，16篇通讯作者

11、 Xue CY, Li JS, Qi H, Xi FY, Xiang WS, Wang JD, Wang XJ(*). Two new pentanorlanostane metabolites from a soil fungus Curvularia borreriae strain HS-FG-237. J Antibiot (Tokyo). 2013, 66(12):735-7, doi: 10.1038/ja.2013.85 (SCI, IF2.191 in 2013)

12、 Wang XiangJing, Zang Bo, Yan YiJun, An Jing, Zhang Ji, Liu ChongXi, Li Ming and Xiang WenSheng(*). Characterization and analysis of industrial strain Streptomyces bingchenggensis by genome sequence and gene microarray. Genome, 2013,56(11):677-89(SCI, IF1.668 in 2013)

13、 Wan-Qian Guo, Shan-Shan Yang, Wen-Sheng Xiang, Xiang-Jing Wang, Nan-Qi Ren, Minimization of excess sludge production by in-situ activated sludge treatment processes-A comprehensive review, Biotechnology Advances, 2013, 31(8):1386-1396, doi: 10.1016/j.biotechadv.2013.06.003 (SCI, IF9.599 in 2013)

14、 Ji Zhang, Jing An, Ji-Jia Wang, Yi-Jun Yan, Hai-Rong He, Xiang-Jing Wang, Wen-Sheng Xiang(*). Genetic engineering of Streptomyces bingchenggensis to produce milbemycins A3/A4 as main components and eliminate the biosynthesis of nanchangmycin. Appl Microbiol Biotechnol. 2013 (97):10091-8, DOI 10.1007/s00253--013-5255-5 (SCI, IF3.689 in 2013)

15、 Yu C, Liu C, Wang X, Zhao J, Yang L, Gao R, Zhang Y，Xiang W(*). Streptomyces polyrhachii sp. nov., a novel actinomycete isolated from an edible Chinese black ant (Polyrhachis vicina Roger). Antonie Van Leeuwenhoek, 2013,104:1013-9 (SCI, IF 2.072 in 2013)

16、 Chongxi Liu, Xiangjing Wang, Junwei Zhao, Qianfeng Liu, Liang Wang, Xuejiao Guan, Hairong He, Wensheng Xiang (*). Streptomyces harbinensis sp. nov., a novel endophytic actinomycete that produces ikarugamycin isolated from soybean root (Glycine max (L.) Merr). Int J Syst Evol Microbiol 2013,63(10):3579-84, doi:10.1099/ijs.0.050088-0. (SCI, IF2.112 in 2013)

17、 Xiang-Jing Wang, Ji Zhang, Jidong Wang, Pingting Qian, Chongxi Liu, Wensheng Xiang(*). Novel cyclopentenone derivatives produced by a rare actinobacterial strain Actinoalloteichus nanshanensis sp. nov. NEAU 119, Natural Product Research, 2013, 27(20):1863-9DOI:10.1080/**.2013.771349 (SCI, IF1.031 in 2013)

18、 Ji Zhang, Xiangjing Wang, Jinnao Diao, Hairong He, Yuejing Zhang, Wensheng Xiang (*). Streptomycin resistance-aided genome shuffling to improve doramectin productivity of Streptomyces avermitilis NEAU1069. Journal Industrial Microbiology & Biotechnology, 2013, 63(7): 2418-2423, doi.10.1007/s10295-013-1280-8 (SCI, IF2.321 in 2013)

19、 Xiangjing Wang, Junwei Zhao, Chongxi Liu, Jidong Wang, Yue Shen, Feiyu Jia, Liang Wang, Ji Zhang, Chao Yu and Wensheng Xiang (*). Nonomuraea solani sp. nov., a novel actinomycete isolated from eggplant root (Solanum melongena L.), Int J Syst Evol Microbiol 2013, 63:2418-23, doi:10.1099/ijs.0.045617-0. (SCI, IF2.112 in 2013)

20、 Huanqing Wang, Fengshou Dong, Yuanbo Li, Xiu Cheng, Youpu Cheng, Wensheng Xiang, Yongquan Zheng, Enantioselective Determination of the Insecticide Indoxacarb in Cucumber and Tomato by Chiral Liquid Chromatography–Tandem Mass Spectrometry, Chirality, 2013,25(6):350-4 (SCI, IF1.718 in 2013)

21、 Pang YW, Zhang LJ, Fang JS, Liu QF, Zhang H, Xiang WS, Wang JD, Wang XJ(*). Two new antitumor constituents from a soil fungus Curvularia inaequalis (strain HS-FG-257). J Antibiot (Tokyo). 2013, 66(5):287-9. doi: 10.1038/ja.2012.128 (SCI, IF2.191 in 2013)

22、 Di Xi, Da Teng, Xiumin Wang, Ruoyu Mao, Yalin Yang, Wensheng Xiang, Jianhua Wang, Design, expression and characterization of the hybrid antimicrobial peptide LHP7, connected by a ?exible linker, against Staphylococcus and Streptococcus, Process Biochemistry, 2013, 48: 453-461. doi.org/10.1016/j.procbio.2013.01.008 (SCI, IF2.414 in 2013)

23、 Xiangjing Wang, Feiyu Jia, Chongxi Liu, Junwei Zhao, Liang Wang, Yue Shen, Jidong Wang, Ji Zhang, Chuang Li, Wensheng Xiang (*). Xiangella phaseoli gen. nov., sp. nov., a new member of the family Micromonosporaceae, Int J Syst Evol Microbiol, 2013, 63: 2138-2145, doi:10.1099/ijs.0.045732-0. (SCI, IF2.112 in 2013)

24、 Qian-Feng Liu, Ji-Dong Wang, Xiang-Jing Wang, Chong-Xi Liu, Ji Zhang, Yan-Wei Pang, Chao Yu & Wensheng Xiang(*). Two new piperidine alkaloids from Streptomyces sp. NEAU-Z4, Journal of Asian Natural Products Research, 2013,15(3):221-4 DOI:10.1080/**.2012.761209 (SCI, IF0.948 in 2013)

25、 Lou Xi-yu, Yang Xuan, Ding Yi-li, Wang Jian-jun, Yan Qing-yan, Huang Xian-gui, Guo Yang-hui, Wang Xiang-jing, Xiang Wen-sheng (*), Synthesis of olaparib derivatives and their anti-tumor activities, Chem. Res. Chin. Univ., 2013, 29(2):231-235 (SCI, IF0.735 in 2013)

26、 Ling Jiang, Yan Liu, Yang Song, Amanda N. Saaredra, Songqin Pan, Wensheng Xiang(*), Jiayu Liao, Internal Calibration F?rster Resonance Energy Transfer Assay: A Real-Time Approach for Determining Protease Kinetics, Sensors, 2013, 13, 4553-4570; doi:10.3390/s**(SCI, IF1.953 in 2013)

27、 Huifeng Zhang, Haibin Wang, Mei Liu, Tao Zhang, Ji Zhang, Xiangjing Wang, Wensheng Xiang (*). Rational development of a serum-free medium and fed-batch process for a GS-CHO cell line expressing recombinant antibody, Cytotechnology, 2013:65:363-8, DOI 10.1007/s10616-012-9488-4 (SCI, IF1.315 in 2013)

28、 Liu C, Wang X, Yan Y, Wang J, Zhang B, Zhang J, Xiang W (*). Streptomyces heilongjiangensis sp. nov., a novel actinomycete that produces borrelidin isolated from the root surface of soybean (Glycine max (L.) Merr), Int J Syst Evol Microbiol, 2013, 63(3):1030-6, doi:10.1099/ijs.0.041483-0. Jun 15 (SCI, IF2.112 in 2013)

29、 Yue Shen, Chongxi Liu, Xiangjing Wang, Junwei Zhao, Feiyu Jia, Yuqin Zhang, Liang Wang, Deguang Yang & Wensheng Xiang (*). Actinoplanes hulinensis sp. nov., a novel actinomycete isolated from soybean root (Glycine max (L.) Merr), Antonie van Leeuwenhoek 2013, 103(2):293-8, doi: 10.1007/s10482-012-9809-9, (SCI, IF2.072 in 2013)

30、 Feiyu Jia, Chongxi Liu, Xiangjing Wang, Junwei Zhao, Qianfeng Liu, Ji Zhang, Ruixia Gao, Wensheng Xiang(*). Wangella harbinensis gen. nov., sp. nov., a new member of the family Micromonosporaceae, Antonie van Leeuwenhoek, 2013, 103(2):399-408, DOI 10.1007/s10482-012-9820-1(SCI, IF2.072 in 2013)
2012年，8篇，7篇通讯作者

31、 Ya-Mei Gao, Xiang-Jing Wang, Ji Zhang, Ming Li, Chong-Xi Liu, Jing An, Ling Jiang, Wen-Sheng Xiang(*). Borrelidin, a potent antifungal agent: insight into the antifungal mechanism against Phytophthora sojae, Journal of Agricultural and Food Chemistry, 2012, 60(39):9874-81, (SCI, IF 2.906 in 2013)

32、 Tao Zhang, Yongliang Yan, Sheng He, Shuzhen Ping, Khandakar Mohiul Alam, Yunlei Han, Xiaodong Liu, Wei Lu, Wei Zhang, Ming Chen, Wensheng Xiang, Xiangjing Wang (*), Min Lin. Involvement of the ammonium transporter AmtB in nitrogenase regulation and ammonium excretion in Pseudomonas stutzeri A1501, Research in Microbiology, 2012,63: 332-9 (SCI, IF2.889 in 2013)

33、 Liang He, Xiang Jing Wang, Ji Zhang, Wen Sheng Xiang (*). Practical synthesis of methyl (E)-2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate, a key intermediate of Montelukast, Chinese Chemical Letters, 2012, 23(5): 518-20(SCI, IF1.21 in 2013)

34、 Qijun Zhang, Peng Sun, Guojun Zheng, Wensheng Xiang (*). Design and synthesis of 3-(2-ethyl-4-(2-(2-(4-fluorophenyl)-5-methyloxazol-4-yl)ethoxy) phenyl)propanoic acid: a novel triple-acting PPAR α, γ and δ agonist, Chemistry Letters, 2012, 41(4): 406-8(SCI, IF1.594 in 2013)

35、 Yang MJ, Wang XJ, Yang ZY, An J, Xiang WS (*). Bioconversion of ethyl (R)-4-cyano-3-hydroxybutyate into (R)-ethyl-3-hydroxyglutarate via an indirect pathway by Rhodococcus boritolerans, Biotechnology Letter, 2012, 34(5): 901-5, (SCI, IF1.853 in 2013)

36、 Sheng-Xiong Huang, Xiang-Jing Wang, Yijun Yan, Ji-Dong Wang, Ji Zhang, Cong-Xi Liu, Wen-Sheng Xiang(*), Ben Shen. Neaumycin: a New Macrolide from Streptomyces sp. NEAU-x211, Organic Letters, 2012, 14(5): 1254-7, (SCI, IF6.142in 2013)

37、 Ping Wang, Guo-jun Zheng, Ya-ping Wang, Xiang-jing Wang, He-geng Wei, Wen-sheng Xiang (*). Highly practical and cost-efficient synthesis of telmisartan: an antihypertensive drug, Tetrahedron, 2012(68):2509-2512 (SCI, IF 2.803 in 2013)

38、 Liu Chongxi, Zhang Ji, Wang Xiangjing, Qian Pingting, Wang Jidong, Gao Yamei, Yan Yijun, Zhang Shuzhen, Xu Pengfei, Li Wenbin, Xiang Wensheng (*). Antifungal activity of borrelidin produced by a Streptomyces strain isolated from soybean, Journal of Agricultural and Food Chemistry, 2012, 60:1251-1257, (SCI, IF 2.906 in 2013; IF3.288, 5-Year Impact Factor)
2011年，14篇，13篇第一和通讯作者

39、 Zhang BX, Zhang H, Wang XJ, Wang JD, Liu CX, Xiang WS (*), New milbemycins from mutant Streptomyces bingchenggensis X-4, Journal of Antibiotics. 2011,64(11):753-756 (SCI, IF2.191 in 2013)

40、 Zhang Baoxin, Wang Xiangjing and Wen-Sheng Xiang (*),Optimization of fermentation medium for enhanced production of milbemycin by a mutant of Streptomyces bingchenggensis BC-X-1 using response surface methodology, African Journal of Biotechnology,10(37):7225-7235

41、 Xiang-Jing Wang, Ji Zhang, Ji-Dong Wang, Chong-Xi Liu, and Wen-Sheng Xiang (*), Four New Doramectin Congeners with Acaricidal and Insecticidal Activity from Streptomyces avermitilis NEAU1069, Chemistry & Biodiversity, 2011,8(11):2117-2125, (SCI, IF1.808 in 2013)

42、 Jian Gao, Yang Hui Guo, Ya Ping Wang, Xiang Jing Wang, Wen Sheng Xiang (*), A novel and efficient route for the preparation of atorvastatin, Chinese Chemical Letters, 2011,22 (10):1159-1162(SCI, IF1.21 in 2013)

43、 Wang JD, Jiang N, Zhang H, Ying LP, Wang CX, Xiang WS, Wu B, Wang HB, Bai H. New epothilone congeners from Sorangium cellulosum strain So0157-2, Nat Prod Res., 2011, 25(18):1707-12(SCI, IF1.031 in 2013)

44、 Xiang-Jing Wang, Ji-Jia Wang, Ji-Dong Wang, Ji Zhang, Mei-Dong Xu and Wen-Sheng Xiang (*), Two new doramectin analogs from Streptomyces avermitilis NEAU1069: Fermentation, Isolation and Structure Elucidation, Journal of Antibiotics. 2011,64(8):591-4 (SCI, IF2.191 in 2013)

45、 Wang XJ, Zhang J, Liu CX, Gong DL, Zhang H, Wang JD, Yan YJ, Xiang WS (*), A novel macrocyclic lactone with insecticidal bioactivity from Streptomyces microflavus neau3. Bioorg Med Chem Lett. 2011;21(18):5145-8(SCI, IF2.338 in 2013)

46、 Zhang J, Wang X, Yan Y, Xiang W (*). Comparative studies on the interaction of genistein, 8-chlorogenistein and 3',8-dichlorogenistein with bovine serum albumin, J Agric Food Chem. 2011, 59(13):7506-7513(SCI, IF 2.906 in 2013; IF3.288, 5-Year Impact Factor)

47、 Dian-Liang Gong, Xiang-Jing Wang, Zhi-Dan Xiang, Ji-Dong Wang, Hui Zhang, Chong-Xi Liu, Ji Zhang, Wen-Sheng Xiang (*). Diphenyl etheric metabolites from Streptomyces sp. neau50. Journal of Antibiotics. 2011.64:465-467 (SCI, IF2.191 in 2013)

48、 Xiang-Jing Wang, Zhi-Dan Xiang, Dian-Liang Gong, Ji-Dong Wang, Chong-Xi Liu, Zhao-Xiang Zhu, Yi-Jun Yan, Wen-Sheng Xiang (*). A new okicenone analog from Streptomyces sp. NEAU-W13. Journal of Antibiotics, 2011, 64:459-460 (SCI, IF2.191 in 2013)

49、 Aili Gao, Hongsheng Ling, Xiangjing Wang, Xiangtong Zhang, Meng Jing, Ji Zhang, Yijun Yan and Wensheng Xiang (*). Reversal effects of two new milbemycin compounds on multidrug resistance in MCF-7/adr cells in vitro, European Journal of Pharmacology, 2011, 659:108-113 (SCI, IF2.592 in 2013)

50、 Wensheng Xiang, Chongxi Liu, Xiangjing Wang, Jing Du, Ying Huang, Lijun Xi. Actinoalloteichus nanshanensis sp. nov., a novel actinomycete isolated from the rhizosphere of a fig tree (Ficus religiosa), International Journal of Systematic and Evolutionary Microbiology, 2011,61:1165-1169 (SCI, IF 2.112 in 2013; IF2.347, 5-Year Impact Factor)

51、 Xiang-Jing Wang, Dian-Liang Gong, Ji-Dong Wang, Ji Zhang, Chong-Xi Liu, Wen-Sheng Xiang (*), A new quinoline derivative with antitumor activity from Streptomyces sp. neau50, Bioorganic & Medicinal Chemistry Letters, 2011(21):2313-2315, (SCI, IF2.338 in 2013)

52、 Wu Ying Qiu, Zheng Guo Jun, Wang Ya Ping, Wang Xing Jing, Xiang Wen Sheng (*), Novel Method for Synthesis of Diarylpyrazole Derivatives as Cannabinoid CB1 Receptor Antagonists. Chemical Research in Chinese Universites, 2011,27(1):66-69 (SCI, IF0.735 in 2013)
2010年，11篇，9篇第一和通讯作者

53、 Qianqian Xu, Wensheng Xiang, Jichang Li, Yong Liu, Xiaolei Yu, Yaoteng Zhang, Mingli Qu. Development and validation of an HPLC-FLD method for milbemectin quantification in dog plasma. Journal of Chromatography B, 2010, 878 (22): 2013-2017（IF2.487 in 2013)

54、 Wan-Qian Guo, Nan-Qi Ren, Xiang-Jing Wang, Wen-Sheng Xiang，Accelerated startup of biological hydrogen production process by addition of Ethanoligenens harbinense B49 in a bio?lm-based column reactor, Int J Hydrogen Energy, 2010, 35: 13407-13412 (SCI, IF3.548 in 2013)

55、 Xiang-Jing Wang, Yi-Jun Yan, Bo Zhang, Jing An, Ji-Jia Wang, Jun Tian, Ling Jiang, Yi-Hua Chen, Sheng-Xiong Huang, Min Yin, Ji Zhang, Ai-Li Gao, Chong-Xi Liu, Zhao-Xiang Zhu, and Wen-Sheng Xiang (*), Genome Sequence of the Milbemycins-producing Bacterium Streptomyces bingchenggensis, Journal of Bacteriology, 2010 192(17):4526-7 (SCI, IF3.194 in 2013; IF3.593, 5-Year Impact Factor)

56、 Wensheng Xiang, Aili Gao, Hongsheng Liang, Changyu Li, Jiguo Gao, Qing Wang, Bao Shuang, Xiangjing Wang, Reversal of P-glycoprotein-mediated multidrug resistance in vitro by milbemycin compounds in adriamycin-resistant human breast carcinoma (MCF-7/adr) cells, Toxicology in Vitro, 2010, 24:1474-1481 (SCI, IF2.65 in 2013)

57、 Ji Zhang, Xiang-Jing Wang, Yi-Jun Yan, Ling Jiang, Ji-Dong Wang, Bao-Ju Li, Wen-Sheng Xiang (*), Isolation and identification of 5-hydroxyl-5-methyl-2-hexenoic acid from Actinoplanes sp. HBDN08 with antifungal activity, Bioresource Technology, 2010,(101):8383-8388 (SCI, IF 4.75 in 2013; IF5.172, 5-Year Impact Factor)

58、 Xiang-Jing Wang, Cheng-Qin Wang, Xiao-Lin Sun, Wen-Sheng Xiang (*). 5-Ketoreductase from Streptomyces bingchengensis: overexpression and preliminary characterization. Biotechnology Letter, 2010, 32: 1497-1502 (SCI, IF1.853 in 2013)

59、 Ping Wang, Guo-jun Zheng, Ya-ping Wang, Xiang-jing Wang, Wen-sheng Xiang (*), A novel and practical synthesis of substituted 2-ethoxy benzimidazole: candesartan cilexetil，Tetrahedron, 2010 (66 ): 5402-5406 (SCI, IF2.803 in 2013)

60、 Wen-Sheng Xiang, Ji-Dong Wang, Ming Wang, Xiang-Jing Wang，New nemadectin congener from Streptomyces microflavus neau3: fermentation, isolation, structure elucidation and biological activities, J. Antibiotics, 2010 63(4):171-175 (SCI, IF2.191 in 2013)

61、 Aili Gao, Xiangjing Wang, Wensheng Xiang (*), Reversal of P-glycoprotein mediated multidrug resistance in vitro by doramectin and nemadectin, J. of Pharmacy and Pharmacology, 2010, 62 (3):393-399 (SCI, IF2.033 in 2013)

62、 Xiang-Jing Wang, Ming Wang, Ji-Dong Wang, Wen-Sheng Xiang (*), Isolation and Identification of Novel Macrocyclic Lactones from S. Avermitilis NEAU1069 with Acaricidal and Nematocidal Activity, J. of Agricultural & Food Chemistry, 2010,58:2710-2714 (SCI, IF2.906 in 2013, IF3.288, 5-Year Impact Factor)

63、 Wen-Seng Xiang, Ji Zhang, Ji-Dong Wang, Zhi-Dan Xiang, Xiang-Jing Wang，Isolation and Identification of Chlorinated Genistein from Actinoplanes sp. HBDN08 with Antioxidant and Antitumor Activities, J. of Agricultural & Food Chemistry, 2010,58(3):1933-1938 (SCI, IF2.906 in 2013)
2009年，9篇，8篇第一和通讯作者

64、 Lu Shi-Xiang, Guo Yang-Hui, Wang Xiang-Jing, Xiang Wen-Sheng (*). A novel synthesis of (R)-4-cyano-3-hydroxybutyric acid ethyl ester, Chinese Journal of Organic Chemistry, 2009,29(12):1997-1999 (SCI, IF0.741 in 2013)

65、 Wen-Sheng Xiang, Ji-Dong Wang, Xiang-Jing Wang, Ji Zhang, Bingchamides A and B, two novel cyclic pentapeptides from the Streptomyces bingchenggensis: fermentation, isolation, structure elucidation and biological properties, J. Antibiotics, 2009, 62(9):501-505 (SCI, IF2.191 in 2013)

66、 Ming Wang, Xiao-Hu Yang, Ji-Dong Wang, Xiang-Jing Wang, Zheng-Jie Chen, Wen-Sheng Xiang (*). New β-Class Milbemycin Compound from Streptomyces avermitilis NEAU1069: Fermentation, Isolation and Structure Elucidation, J. Antibiotics, 2009, 62(10):587-591 (SCI, IF2.191 in 2013)

67、 Xiang-Jing Wang, Suo-Lian Guo, Wan-Qian Guo, Wen-Sheng Xiang (*), Role of nsdA in Negative Regulation of Antibiotic Production and Morphological Differentiation in Streptomyces bingchengensis, J. Antibiotics, 2009, 62(6):309-13 (SCI, IF2.191 in 2013)

68、 Xiang-Jing Wang, Xiao-Chong Wang, Wen-Sheng Xiang(*). Improvement of milbemycin-producing Streptomyces bingchenggensis by rational screening of ultraviolet- and chemically induced mutants, World Journal of Microbiology and Biotechnology, 2009, 25:1051-1056 (SCI, IF1.262 in 2013)

69、 Xiang-Jing Wang, Ji-Dong Wang, Wen-Sheng Xiang (*). Three new milbemycin derivatives from Streptomyces bingchenggensis, Journal of Asian Natural Products Research, 2009, 11(7), 597-603 (SCI, IF0.948 in 2013)

70、 Wen-Sheng Xiang, Ji-Dong Wang, Xiang-Jing Wang, A novel macrolide compound from the Streptomyces bingchenggensis, Fermentation, Isolation, Structure Elucidation and Biological Properties, J. Antibiotics, 2009, 62(4):229-31 (SCI, IF2.191 in 2013)

71、 Hai Bo Sun, Guo Jun Zheng, Ya Ping Wang, Xiang Jing Wang, Wen Sheng Xiang(*), Novel synthesis of 2-butyl-5-chloro-3H-imidazole-4-carbaldehyde: A key intermediate of Losartan, Chinese Chemical Letters, 2009, 20: 269-270 (SCI, IF1.21 in 2013)

72、 Wan-Qian Guo, Nan-Qi Ren, Xiang-Jing Wang, Wen-Sheng Xiang, Optimization of culture conditions for hydrogen production by Ethanoligenens harbinense B49 using response surface methodology. Bioresource Technology, 2009, 100(3): 1192-6 (SCI, IF4.75 in 2013)

近五年授权的专利等情况
以第一发明人获授权发明专利10项，其中国际发明专利1项。

其他获奖及荣誉称号
获国家杰出青年基金、省杰出青年基金，入选国家“****”、科技部中青年科技创新领军人才，龙江学者特聘教授、教育部新世纪优秀人才、省****后备人才。

国家自然科学基金委员会第十二届、第十三届专家评审组成员；

中国植物保护学会理事会园林病虫害防治专业委员会第十届副主任委员；

“十一五”、“十二五”黑龙江省生物农药副首席科学家；

黑龙江省第六届、第七届（2010-2012）分析化学学会常务理事；

黑龙江省科学院微生物所博士后工作站主任。