Application of ACO algorithm in protein structure prediction
TANG Hao-xuan, Qu Yi
School of Computer Science and Technology, Harbin Institute of Technology,Harbin 150001,China
Abstract:
The hydrophobic-polar (HP) lattice model is an important simplified model for studying protein folding. In this paper, we present an improved ACO algorithm for the protein structure prediction. In the algorithm, the "lone"ethod is applied to deal with the infeasible structures, and the "oint mutation and reconstruction"ethod is applied in local search phase. The empirical results show that the presented method is feasible and effective to solve the problem of protein structure prediction, and notable improvements in CPU time are obtained.
Key words: protein structure prediction HP lattice model ACO algorithm
DOI：10.11916/j.issn.1005-9113.2009.01.023
Clc Number:TP301.6
Fund:
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Application of ACO algorithm in protein structure prediction
本站小编 哈尔滨工业大学/2019-10-23
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