张雪梅
发布时间：2015-09-21 12:46:28 阅读次数：
个人简历

姓名：张雪梅
性别：女
电子信箱：zhangxuemei@ncst.edu.cn
工作单位及职称：华北理工大学生命科学学院 教授
联系电话: **91
教育背景


1990.9－1995.7，山西医科大学公共卫生专业，本科
1996.9－1999.7，山西医科大学环境卫生与劳动卫生专业，硕士研究生
2003.8－2006.7，中国医学科学院&中国协和医科大学肿瘤学专业，博士研究生
研究工作经历
1999.07－2003.08, 华北煤炭医学院生物系，讲师
2006.07－2007.03，华北煤炭医学院生物系，讲师/副教授
2007.03－2011.01, 美国阿肯色大学医学院，博士后
2011.01－至今，河北联合大学生命科学学院，副教授/教授

社会兼职
1. 中国抗癌协会肿瘤病因学专业委员会委员：自2011年3月
2. 美国癌症研究协会（AACR）高级会员：自2009年
3. 美国科学促进会（AAAS）会员：自2010年
4. “Molecular Carcinogenesis” 审稿人
5. “BMC Cancer” 审稿人
6. “Tumor Biology”审稿人
7. “Plos One”审稿人
8. “Tumori”审稿人

获得荣誉与奖励
1. 2015年，获“河北省优秀科技工作者”称号
2. 2014年，获“河北省优秀留学回国人员”称号
3. 2014年，获“河北省唐山市劳动模范”称号
4. 2013年，获“河北省科技进步奖”三等奖
（项目名称：消化系统肿瘤与遗传变异；证书编号2013JB3031-1）
5. 2013年，获“河北省冶金青年科技奖”
6. 2013年，获唐山市“市直教育系统优秀共产党员”
7. 2013年，获“唐山市科学技术奖”一等奖
（项目名称：消化系统肿瘤与遗传变异关系研究；证书编号：2013JB1005-1）
8. 2012年，获“北京市科学技术奖”二等奖
（项目名称：评价肿瘤风险与治疗反应的遗传标记物研究及其应用；证书编号：2012医－2－005－07）
9. 2012年，获“中华医学科技奖”三等奖
（项目名称：评价肿瘤风险与治疗反应的遗传标记物研究及其应用；证书编号：**P0807）
10. 2012年，河北省杰出青年科学基金获得者
11. 2012年，获“唐山市科学技术奖”二等奖（项目名称：基因遗传变异和消化系统肿瘤遗传易感性 2012JB2-70-02）
12. 2012年度河北联合大学“先进工作者”
13. 2011年，入选教育部“新世纪优秀人才支持计划”
14. 2011年，入选河北省“三三三人才工程”第二层次人才
15. 2011年度河北联合大学“先进工作者”
16. 2008年，获“国家科学技术进步奖”二等奖（第六）
(项目名称：88－1项目；证书编号2008－J-24400－2－06－R06)
17. 2008年，“环氧化酶-2功能性遗传变异与食管癌及胃癌易感性相关”获“全国百篇优秀博士学位论文”(证书编号：**)
18. 2008年，获“Aspen Cancer Conference Fellow Award”
19. 2006年，获中国医学科学院肿瘤医院“天衡杯”2006年度影响因子最高论文奖、二等奖和三等奖各一项
20. 2006年，获“谈家桢九源生命科学奖学金”二等奖
21. 2005年，获“北京市科学技术奖”一等奖
（项目名称：单核苷酸多态与肿瘤的研究；项目编号：2005医-1-005-11）
22. 2005年，获“中国协和医科大学优秀研究生”
23. 2002年，获“河北省医学教育优秀教师”
在研项目
唐山市科技创新团队培养计划（2015.1-2017.12）项目编号：**B
项目名称：补体通路关键基因对肺癌发病及预后的影响及其机制研究
资助金额：20万
河北省普通高等学校高层次人才科学研究计划（2014.1-2016.12）(项目负责人)项目编号：GCC**
项目名称：ERCC1和XPF影响非小细胞肺癌化疗敏感性的机制研究
资助金额：10万
河北省高层次人才资助项目（2015.1-2017.12）(项目负责人)项目编号：A**
项目名称：TNFSF15与肺癌发病风险及预后关系研究
资助金额：1万
河北省高等学校创新团队领军人才培育计划（2014.1-2016.12）（项目负责人）项目编号：LJRC001
项目名称：补体通路关键基因影响肺癌发生的生物学机制研究及临床应用
资助金额：60万
国家自然科学基金（2013.1-2016.12）（项目负责人）项目名称: 转录偶联修复基因在非小细胞肺癌异常表达的分子机制研究
项目编号: **
资助金额：75万元
结题项目
教育部“全国博士学位论文作者专项基金资助项目”（2012.1-2013.12）（项目负责人）项目名称：转录偶联修复关键基因遗传变异与非小细胞肺癌
项目编号：201274
资助金额：30万元
国家自然科学基金（2012.1-2014.12)（项目负责人）项目名称: 补体通路调节基因遗传变异与肺癌发病风险关系研究
项目编号: **
资助金额：22万元
国家自然科学基金（2011.1-2013.12）（第二名）项目名称: 肾脏特异表达基因TMEM174的功能和作用机制研究
项目编号: **
资助金额：32万元
国家重点实验室开放课题（2012.1-2013.12）（项目负责人）项目名称：补体通路关键基因单核苷酸多态与肺癌遗传易感性相关关系研究
项目编号：SKL-KF-2011-05
资助金额：10万元
教育部“新世纪优秀人才支持计划”（2012.1-2014.12）（项目负责人）项目名称：胃癌分子流行病学－补体通路
项目编号：NCET-11-0933
资助金额：50万元
河北省“杰出青年科学基金”（2012.1-2014.12）（项目负责人）项目名称：转录偶联修复关键基因遗传变异与肺癌相关关系研究
项目编号：H**
资助金额：30万元
发表科研论文(SCI收录)
1. Zhao L, Zhang Z, Lin J, Cao L, He B, Han S, Zhang X*. Complement receptor 1 genetic variants contribute to the susceptibility to gastric cancer in Chinese population. Journal of Cancer, 2015; 6(6): 525-530. (*通讯作者)
2. Liu Y, Bi Y, Lin J, Cao L, He B, Zhang Z, Cui Y, Zhang X*. Tag SNPs of CFI contributed to the susceptibility for non-small cell lung cancer in Chinese population. Tumor Biology, 2015; 36(3): 1955-1962. (*通讯作者)
3. Song Q，Zhang Z, Liu Y, Han S, Zhang X*. The tag SNP rs** in decay-accelerating factor is associated with the susceptibility to gastric cancer. Molecular Immunology, 2015; 63(2):473-478. (*通讯作者)
4. Lin J, He B, Cao L, Zhang Z, Liu H, Rao J, Liu Y, Shao S, Wang G, Zhang X*. CYP1A1 Ile462Val polymorphism and the risk of non-small cell lung cancer in a Chinese population. Tumori, 2014; 100(5):547-552. (*通讯作者)
5. Zhang Z, Yu D, Lu J, Zhai K, Cao L, Rao J, Liu Y, Zhang X*, Guo Y*. Functional genetic variants of TNFSF15 and their association with gastric adenocarcinoma: A case-control study. Plos One , 2014; 9(9): e108321. (*通讯作者)
6. Liu Y, Cao L, Chang J, Lin J, He B, Rao J, Zhang Z, Zhang X*. XPF -673C>T polymorphism effect on the susceptibility to esophageal cancer in Chinese population. Plos One, 2014; 9(4): e94136. (*通讯作者)
7. Yang HP, Liu JF, Rao J, Zhang XM,Qian HL, Niu XQ, Zhao ZL. Insulin-like growth factor binding protein-3 (IGFBP-3) genetic variant and the risk of esophageal squamous cell carcinoma in a Chinese insulation. Genetics and Molecular Research. 2014; 13(2): 4146-53.
8. Yu X, Rao J, Lin J, Zhang Z, Cao L, Zhang X*. Tag SNPs in complement receptor-1 contribute to the susceptibility to non-small cell lung cancer.Molecular Cancer, 2014; 13(1): 56. (*通讯作者)2014 Mar 12
9. Cao L, Lin J, He B, Wang H, Rao J, Liu Y, Zhang X*. A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma. Tumor Biology. 2014; 35(1): 455-462. (*通讯作者)2013 Aug 11.
10. Zhang X, Huang M, Wu X, Kadlubar S, Lin J, Yu X, Fan C, Ning B, Kadlubar FF.GSTM1 copy number and promoter haplotype as predictors for risk of recurrenceand/or second primary tumor in patients with head and neck cancer. PharmgenomicsPers Med. 2013;6:9-17.
11. Lin Z, Lin Y, Zhang X, Kadlubar S, Tuo J, Green B, Deng H, Ning B. Differential promoter activities of functional haplotypes in the 5’-flanking region of human sulfotransferase 1A1.J BiochemMolToxicol. 2012; 26(10): 422-428.
12. Zhang X, Lin J, Wu X, Lin Z, Ning B, Kadlubar S, Kadlubar F. Association between GSTM1 copy number, promoter variants and susceptibility to urinary bladder cancer.Int J MolEpidemiol Genet. 2012; 3(3): 228-236.
13. Zhang Z, Yu X, Guo Y, Song W, Yu D, Zhang X*.Genetic variant in CASP3 affects promoter activity and risk of esophageal squamous cell carcinoma.Cancer Science. 2012; 103(3): 555-60.(*通讯作者)
14. Zhang Z, Yu D, Yuan J, Guo Y, Wang H, Zhang X*. Cigarette smoking strongly modifies the association of CFH variant and the risk of lung cancer.Cancer Epidemiology.2012; 36 (2): e111-5.(*通讯作者)
15. Yu X, Zhang X, Dhakal I, Beggs M, Kadlubar S, Luo D. Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells. BMC Cancer 2012; 12(1): 29
16. Zhang J, Zhang X, Dhakal IB, Gross MD, Kadlubar FF, Anderson KE. Sequence variants in antioxidant defense and DNA repair genes, dietary antioxidants, and pancreatic cancer risk.Int J Mol Epidemiol Genet. 2011 Aug 30;2(3):236-44.
17. Zhang X*, Zhong R, Liu L, Wang Y, Yuan J, Wang P, Sun C, Zhang Z, Song W, Miao X*. Smoking and COX-2 functional polymorphisms interact to increase the risk of gastric cardia adenocarcinoma in Chinese population.Plos one 2011: 6(7): e21894. (*通讯作者)
18. Zhang X, Zhong R, Zhang Z, Yuan J, Liu L, Wang Y, Kadlubar S, Feng F, Miao X. Interaction of Cyclooxygenase-2 Promoter Polymorphisms With Helicobacter pylori Infection and Risk of Gastric Cancer. Molecular Carcinogenesis. 2011; 50 (11): 876-883.
19. Liu L, Wu C, Wang Y, Zhong R, Wang F, Zhang X, Duan S, Lou J, Yu D, Tan W, Yuan J, Wu T, Nie S, Miao X, Lin D. Association of candidate genetic variations with gastric cardia adenocarcinoma in Chinese population: a multiple-interaction analysis.Carcinogenesis 2011:32:336-342. PMID: **
20. Knappskog S, Bj?rnslett M, Myklebust LM, Huijts PE, Vreeswijk MP, Edvardsen H, Guo Y, Zhang X, Yang M, Ylisaukko-Oja SK, Alhopuro P, Arola J, Tollenaar RA, van Asperen CJ, Seynaeve C, Staalesen V, Chrisanthar R, L?kkevik E, Salvesen HB, Evans DG, Newman WG, Lin D, Aaltonen LA, B?rresen-Dale AL, Tell GS, Stoltenberg C, Romundstad P, Hveem K, Lillehaug JR, Vatten L, Devilee P, D?rum A, L?nning PE. The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians.Cancer Cell. 2011;19 (2):273-82. PMID: **
21. Liu L, Yuan P, Wu C, Zhang X, Wang F, Guo H, Zhong R, Xu Y, Wu J, Yu D, Wu T, Zhang X, Nie S, Miao X, Lin D. Assessment of XPD Lys751Gln and XRCC1 T-77C polymorphisms in advanced non-small-cell lung cancer patients treated with platinum-based chemotherapy.Lung Cancer. 2011;73: 110-115. PMID: **
22. Yu X, Dhakal I, Beggs M, Edavana V, Williams S, Zhang X, Mercer K, Ning B, Lang N, Kadlubar F, Kadlubar S. Functional genetic variants in the 3’-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity.Toxicological Sciences 2010:118(2); 391-403. PMID: **
23. Guo Y, Zhang X*, Yang M, Miao X, Shi Y, Yao J, Tan W, Sun T, Zhao D, Yu D, Liu J, Lin D. Functional evaluation of missense variations in the human MAD1L1 and MAD2L1 genes and their impact on susceptibility to lung cancer.Journal of Medical Genetics 2010: 47(9); 616-622 (*并列第一作者). PMID: **
24. Zhao D, Zhang X*, Guo Y, Tan W, Lin D. Cyclooxygenase-2 Gly587Arg variant is associated with differential enzymatic activity and risk of esophageal squamous-cell carcinoma. Molecular Carcinogenesis 2009; 48(10): 934-941(*并列第一作者). PMID: **
25. Zhao D, Xu D, Zhang X, Wang L, Tan W, Guo Y, Yu D, Li H, Zhao P, Lin D. Interaction of Cyclooxygenase-2 variants and smoking in pancreatic cancer: a possible role of nucleophosmin.Gastroenterology 2009; 136(5): 1659-1668. PMID: **
26. Yu D, Zhang X*, Liu J, Yuan P, Tan W, Guo Y, Sun T, Zhao D, Ming Y, Liu J, Xu B, Lin D. Characterization of Functional Excision Repair Cross-Complementation Group 1 Variants and Their Association with Lung Cancer Risk and Prognosis. Clinical Cancer Research2008;14(9):2878–2886 (*并列第一作者). PMID: **
27. Lin Z, Zhang X*, Tu J, Guo Y, Green B, Chan C, Tan W, Huang Y, Ling W, Kadlubar FF,Lin D, Ning BT. A variant of Cokyne Syndrome B gene ERCC6 confers risk of lung cancer.Human Mutation2008;29(1):113–122 (*并列第一作者). PMID: **
28. Yang M, Sun T, Wang L, Yu D, Zhang X, Miao X, Liu J,Zhao D, Li H, Tan W, Lin D. Functional variants in cell death pathway genes and risk of pancreatic cancer.Clinical Cancer Research2008;14(10):3230–3236. PMID: **
29. Zhao D, Sun T, Zhang X*, Guo Y, Yu D, Yang M, Tan W, Wang G, Lin D. Role of CD14 Promoter Polymorphisms in Helicobacter pylori Infection-Related Gastric Carcinoma. Clinical Cancer Research 2007;13(8):2362–2368. (*并列第一作者). PMID: **
30. Guo Y, Zhang X*, Tan W, Miao X, Sun T, Zhao D,Lin D. Platelet 12-lipoxygenase Arg261Gln polymorphism: Functional characterization and association with risk of esophageal squamous cell carcinoma in combination with COX-2 polymorphisms. Pharmacogenetics and Genomics 2007;17(3):197–205. (*并列第一作者) PMID: **
31. Yang M, GuoY, Zhang X, Miao X, Tan W, Sun T, Zhao D, Liu J, Lin D. Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer.Carcinogenesis2007;28(9):1996–2001. PMID: **
32. Tan W, Wu J, Zhang X*, Guo YL, Liu J, Sun T, Zhang B, Zhao D, Yang M, Yu D, Lin D. Associations of functional polymorphisms in cyclooxygenase-2 and platelet 12-lipoxygenase with risk of occurrence and advanced disease status of colorectal cancer.Carcinogenesis2007;28(6):1197–1201(*并列第一作者). PMID: **
33. Zheng L, Dai H, Zhou M, Li M, Singh P, Qiu J, Tsark W, Huang Q, Kernstine K, Zhang X, Lin D, Shen B. Fen1 mutations result in autoimmunity, chronic inflammation and cancers. Nature Medicine 2007;13(7):812–819. PMID: **
34. Sun T, Gao Y, Tan W, Ma S, Shi Y, Yao J, Guo Y, Yang M, Zhang X, Zhang Q, Zeng C, Lin DX. A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers.Nature Genetic 2007;39(5):605–613. PMID: **
35. Zhang B, Sun T, Xue L, Han X, Zhang B, Lu N, Shi YK, Tan W, Zhou YF, Zhao D, Zhang X, Guo Y, Lin D. Functional polymorphisms in FAS and FASL contribute to increased apoptosis of tumor infiltration lymphocytes and risk of breast cancer.Carcinogenesis 2007;28(5):1067–1073. PMID: **
36. Miao X, Zhang X*, Zhang L, Guo Y, Hao B, Tan W, He F, Lin D. Adenosine DiphosphateRibosylTransferase and X-Ray Repair Cross-Complementing 1 polymorphisms in Gastric Cardia Cancer.Gastroenterology 2006;131(2):420–427. (*并列第一作者). PMID: **
37. Zhang X, Miao X,Guo Y,Tan T,Zhou Y, Sun T, Wang Y, Lin D. Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. Human Mutation 2006;27(1):110–117. PMID: **
38. Sun T, Gao Y, Tan W, Ma S, Zhang X, Wang Y, Zhang Q, Guo Y, Zhao D, Zeng C, Lin D. Haplotypes in MatrixMetalloproteinase Gene Cluster on Chromosome11q22 Contribute to the Risk of Lung Cancer Development and Progression. Clinical Cancer Research 2006;12(23):7009–7017. PMID: **
39. Li Y, Zhang X, Huang G, Miao X, Guo L, Lin D, Lu S. Identification of a novel polymorphism Arg290Gln of esophageal cancer related gene 1 (ECRG1) and it related risk to esophageal squamous cell carcinoma.Carcinogenesis 2006;27(4):798–802. PMID: **
40. Liu F, Pan K, Zhang X, Zhang Y, Zhang L, Ma J, Lin D, You W. Genetic polymorphisms of cyclooxygenase-2, expression and risk of gastric cancer and its precursors in a Chinese population. Gastroenterology, 2006;130(7):1975–1984. PMID: **
41. Hao B, Miao X, Li Y, Zhang X, Sun T, Liang G, Zhao Y, Zhou Y, Wang H, Chen X, Zhang L, Tan W, Wei Q, Lin D, He F. A novel T-77C polymorphism in DNA repair gene XRCC1 contributes to diminished promoter activity and increased risk of non-small cell lung cancer.Oncogene 2006;25(25):3613–3620. PMID: **
42. Zhang X, Miao X, Tan W, NingB, Liu Z, Hong Y, Song W, Guo Y, Zhang X, Shen Y, Qiang B, Kadlubar FF, LinD. Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer. Gastroenterology 2005;129(2):565–576. PMID: **
43. Zhang X, Miao X, Sun T,Tan W, Qu S, Xiong P, Zhou Y, LinD. Functional polymorphisms in cell death pathway genes FAS and FASL contribute to risk of lung cancer. Journal of Medical Genetics 2005;42(6):479–484. PMCID: PMC**
44. Zhang X, Miao X, Liang G, Hao B, Wang Y, Tan W, Li Y, Guo Y, He F, Wei G, Lin D. Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer. Cancer Research 2005;65(3):722–726. PMID: **
45. Sun T, Zhou Y, Li H, Han X, Shi Y, Wang L, Miao X, Tan W, Zhao D, Zhang X, GuoY,Lin DX. FASL -844C polymorphism is associated with increased activation-induced T cell death and risk of cervical cancer.Journal of Experimental Medicine 2005;202(7):967–974. PMID: **
46. Tan W, Miao X, Wang L, Yu C, Xiong P, Liang G, Sun T, Zhou Y, Zhang X, Li H, Lin DX. Significantincrease in risk of gastroesophageal cancer is associated with interaction between promoter polymorphisms in thymidylate synthase and serum folate status. Carcinogenesis 2005;26(8):1430–1435. PMID: **
47. Zhou Y, Yu C, MiaoX, WangY, TanW, SunT, Zhang X, Xiong P, Lin D.Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility.Carcinogenesis 2005;26(6):1117–1121. PMID: **
48. Hong Y, Miao X,Zhang X,GuoY, Tan W, Liu Z, Lin D. The role of P53 and MDM2 polymorphisms in risk of esophageal squamous cell carcinoma. Cancer Research 2005;65(20):9582–9587. PMID: **
49. Sun T, Miao X, Zhang X, Tan W, Xiong P, Lin D. Polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma. Journal of National Cancer Institute 2004;96(13):1030–1036. PMID: **
50. Miao X, Sun T, Wang Y, Zhang X, Tan W, Lin D. Functional STK15 Phe31Ile polymorphism is associated with the occurrence and advanced disease status of esophageal squamous cell carcinoma. Cancer Research 2004;64(8):2680–2683. PMID: **
发表科研论文（中文）
51. 刘睿，宋琴琴，张志，杨照环，刘英文，张雪梅*. 肿瘤坏死因子-b遗传变异与非小细胞肺癌发病风险遗传易感性的关系. 中华预防医学杂志，2015; 49(1):41-44. (*通讯作者)
52. 刘英文，林佳，何冰，曹蕾，张志，张雪梅*. 着色性干皮病基因F -673C>T遗传变异对食管鳞状细胞癌预后的影响. 中华消化杂志，2014,34(10):693-695. (*通讯作者)
53. 饶娟，姚林，张艳淑，刘睿，王宏戈，张雪梅*. ERCC1基因多态与胃癌易感性相关. 中国公共卫生; 2014, 30(7): 928-930. (*通讯作者)
54. 郭炜妍，戴亮，浦践一，张雪梅*，张国志，徐卫国. 脂氧酶12编码区遗传变异与肝癌发病风险的关系. 中华医学杂志. 2013; 93(46): 3685-3687. (*通讯作者)
55. 曹蕾，何冰，林佳，王宏戈，饶娟，刘英文，张雪梅*. 细胞色素P450 2E1基因多态性与小细胞肺癌相关性分析. 中华流行病学杂志. 2013; 34 (10): 1048-1049 (*通讯作者)
56. 张志，刘睿，杨照环，王光霞，邵莎莎，宋琴琴，张雪梅*. 环氧化酶2遗传变异与吸烟交互作用影响肺癌易感性. 中华预防医学杂志. 2013; 47 (8): 736-739. (*通讯作者)
57. 许东奎，张雪梅，赵平，蔡建春，赵丹，谭文，郭永丽，林东昕. －1195G>A多态对胰腺癌细胞COX2基因转录活性的影响. 中华肝胆外科杂志 2009; 15 (3): 209-212.
58. 许东奎，张雪梅，赵平，蔡建春，赵丹，谭文，郭永丽，林东昕. COX2基因启动子区单核苷酸多态与肝癌遗传易感性的关系. 中华肝胆外科杂志 2008; 14 (12): 840-843.
59. 许东奎，张雪梅，赵平，蔡建春，赵丹，谭文，郭永丽，林东昕.COX2基因启动子区单核苷酸多态与胰腺癌遗传易感性的关系. 中华医学杂志 2008; 88(28):1961-1965.
60. 刘俊鸟，张雪梅，郭永丽，孙瞳，林东昕，谭文. 鼠双微体同源基因2遗传多态与结直肠癌患病风险的相关性. 中华肿瘤杂志2008; 30(5): 335-338
61. 温树信，张雪梅，唐平章，赵丹，郭永丽，谭文，林东昕.XRCC3遗传变异与喉癌和下咽癌发病风险相关研究. 中华耳鼻喉头颈外科杂志 2007; 42(11): 856-859.
62. 张雪梅，缪小平，谭文，孙瞳，郭永丽，赵丹, 林东昕. 环氧化酶2启动子区遗传变异及其与胃癌发病风险的关系. 中国医学科学院院报 2006; 28(2): 119-123.
63. 刘炬，张雪梅，张湘茹，袁芃，徐兵河，林东昕. ERCC6 C6530G单核苷酸多态与局限期小细胞肺癌患者生存相关，中国癌症杂志 2006: 16(11): 943-947
64. 温树信，唐平章，张雪梅，赵丹，郭永丽，谭文，林东昕. 着色性干皮病G组基因多态性与喉癌和喉咽癌风险的相关性. 中国医学科学院学报 2006; 28(5): 703-706.
65. 张志, 缪小平, 谭文, 郭永丽, 张雪梅, 林东昕. DNA修复基因ADPRT和XRCC1遗传变异与胃癌风险. 癌症 2006; 25(1): 7-10.
66. 张雯杰, 缪小平, 孙瞳, 张雪梅, 曲世宁, 谭文, 熊萍, 郑容, 林东昕. STK15基因单核苷酸多态与大肠癌风险. 中华肿瘤杂志 2006; 28(1): 43-46.
67. 袁芃, 缪小平, 张雪梅, 王中华, 谭文, 孙燕, 张湘茹, 徐兵河, 林东昕. DNA损伤修复基因XRCC1和XPD遗传多态与晚期非小细胞肺癌对铂类药物的敏感性. 中华肿瘤杂志 2006; 28(3): 196-199.
68. 袁芃, 缪小平, 张雪梅, 王中华, 谭文, 张湘茹, 孙燕, 徐兵河, 林东昕. 晚期非小细胞肺癌对铂类药物的化疗敏感性与P53和P73基因多态的关系. 中华肿瘤杂志 2006; 28: 107-110.
69. 缪小平, 杨燊, 谭文, 张雪梅, 叶颖江, 林东昕, 王杉. 亚甲基四氢叶酸还原酶基因单核苷酸多态与大肠癌风险. 中华预防医学杂志 2005; 39(6): 409-411.
70. 杨燊, 缪小平, 张雪梅, 孙瞳, 曲世宁, 熊萍, 叶颖江, 郭永丽, 谭文, 王杉, 林东昕. 凋亡相关基因FAS及其配体FASL基因单核苷酸多态与大肠癌风险. 中华医学杂志 2005; 85(30): 2132-2135.
71. 袁芃, 缪小平, 张雪梅, 王中华, 孙燕, 徐兵河,林东昕. XPC和XPD遗传多态与晚期非小细胞肺癌对铂类药的敏感性. 中华医学杂志 2005; 85(14): 972–975.
72. 袁芃，缪小平，张雪梅，王中华，谭文，张湘茹，孙燕，徐兵河，林东昕. 核苷酸切除修复系统基因遗传多态与晚期非小细胞肺癌患者铂类药物敏感性关系. 癌症 2005; 24(12): 1510-1513
73. 张雪梅，缪小平，谭文，曲世宁，孙瞳，周翊峰，林东昕.亚甲基四氢叶酸还原酶基因遗传变异与肺癌. 中国医学科学院学报2005; 27(6): 700-703.
74. 张雪梅，缪小平，熊平，于春媛，谭文，曲世宁，孙瞳，周翊峰，林东昕. 基质金属蛋白酶(MM P)-2和－9功能性单核苷酸多态与胃癌. 癌症2004; 23: 1233-1237.
75. 张志, 张雪梅, 杨文敏, 付占昭. 肺癌患者肺组织DNA加合物的检测及其影响因素. 中国肺癌杂志2003; 6(1): 185-187.
76. 张雪梅，张志，张雪怡，杨文敏. 大气颗粒有机提取物的染色体损伤作用研究. 环境与健康杂志 2002; 19(3): 200-201.
77. 张雪梅，杨文敏，张志. 大气颗粒有机提取物所致小鼠DNA加合物与微核的相关关系研究. 中国公共卫生 2001; 17(1): 11.
参加国际学术会议
1. Cao L, Lin J, He B, Hongge Wang, Juan Rao, Yingwen Liu, Zhang X. A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma. AACR Meeting Abstract, Apr 5-9; 2014:3252
2. Zhang X, Huang M, Wu X, Kadlubar S, Yu X, Caldwell D, Lin J, Ning B, Kadlubar FF. GSTM1 CNV and promoter SNPs are associated with REC/SPT and survival after retinoid acid treatment for head and neck cancer. AACR Meeting Abstract, Apr 2010; 2010: 885.
3. Zhang X, Lin J, Wu X, Kadlubar S, Lin Z, Ning B, and Kadlubar F. Genetic variants of GSTM1 and the risk of bladder cancer in Caucasians. AACR Meeting Abstracts, Apr 2009; 2009: 3056.
4. Zhang J, Dhakal I, Zhang X, Gross M, Lang N, Kadlubar F, and Anderson K. Sequence variance in genes involved in oxidative stress and risk of pancreatic cancer: Effects modified by alcohol intake. AACR Meeting Abstracts, Apr 2009; 2009: 2113.
5. Yu X, Mercer K, Edavana V, Zhang X, Falany C, Kadlubar F, and Kadlubar S. Raloxifene sulfated metabolites induce apoptosis in breast cancer cell lines. AACR Meeting Abstracts, Apr 2009; 2009: 3652.
6. Zhang X, Stone A, Wei Q, Wang L, Millikan R, Ning B, Kadlubar S, and Kadlubar F. Genetic variants of GSTM5, SULT1C2 and CYP39A1 and the risk of breast cancer in Caucasians and African-Americans. AACR Meeting Abstracts, Apr 2008; 2008: 1907.
7. Zhang X,Guo Y, Tuo J, Green B, Wise C, Kadlubar S, Kadlubar F, Lin D, and Ning B. The SNP rs380390 of complement factor H gene is associated with the risk of lung cancer and interacts with ERCC6 SNP rs**. AACR Meeting Abstracts, Apr 2008; 2008: 3125.
8. Ning B, Lin Z, Zhang X, Tuo J, Guo Y, Green B, Chan C, Tan W, Ling W, Kadlubar F, and Lin D. Variant of the Cockayne syndrome B gene ERCC6 confers risk of lung cancer, AACR Meeting Abstracts, Apr 2007; 2007: 818.
9. Sun T, Miao X, Zhang X, Tan W, Xiong P, and Lin D. Functional polymorphisms in the Fas and FasL gene promoters and risk of development and progression of esophageal squamous cell carcinoma. AACR Meeting Abstracts, Mar 2004; 2004: 1045