女

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党员

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硕、博导师

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汉族

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博士毕业

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博士

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河北医科大学第二医院

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专业学位

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现工作单位：河北医科大学第二医院

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所在科室：河北医科大学第二医院妇产科

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职务：产科主任 产前诊断中心主任

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E-mail：xh_hbyd@163.com

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个人简介：主持或参加科研项目及人才计划项目情况：1.河北省卫生厅跟踪项目，荧光定量PCR检测B族链球菌感染与早产及胎膜早破相关性研究，2014-2016，4万元，在研，主持。2.河北省卫生厅医学重点项目，**，膜联蛋白V在子痫前期发生机制中的研究，2011-2013，1万元，结题，主持。3.河北省卫生厅跟踪项目，GL2010-17，子痫前期患者中抗磷脂抗体的临床检测，2010-2012，4万元，结题，主持。4.河北省卫生厅医学重点项目，**，应用荧光原位杂交技术诊断胎儿非整倍体异常，2009-2010，1万元，结题，主持。5.卫生厅医学适用技术跟踪项目计划，GL200721，应用QF-PCR对胎儿非整倍体进行产前诊断，2008-2010，4万元，结题，主持。1.国家卫生计生委医药科技发展中心，维生素 A、E水平与孕期子痫前期相关性研究，2.河北省卫生厅医学适用技术跟踪项目，荧光定量PCR 检测 B 族链球菌感染与早产及胎膜早破相关性研究，3.河北省科技厅计划项目，TFPI-2在子痫前期高凝状态中的作用机制，4.河北省卫生厅医学适用技术跟踪项目， 子痫前期患者中抗磷脂抗体的临床检测，5.河北省卫生厅医学重点项目，应用荧光原位杂交技术诊断胎儿非整倍体异常，6.河北省卫生厅课题，利用 QF-PCR 对胎儿非整倍体进行产前诊断论著：1.Zhang Y, Xin H, et al. Elevated levels of hypoxia-inducible microRNA-210 in pre-eclampsia: new insights into molecular mechanisms for the disease[J]. J CellMolMed, 2012, 16(2): 249-59.（影响因子4.0） 2.Xin H, Zhang Y, Wang H, et al. Alterations of profibrinolytic receptor annexinA2 in pre-eclampsia:A possible role in placental thrombinformation[J]. ThrombRes, 2011, 128(5):563-567.（影响因子3.0）3.Wu Y, Liu S, Xin H,etal.Up-regulation of microRNA-145 promotes differentiation by repressing OCT4 in human endometrial adenocarcinoma cells[J]. Cancer, 2011,117 (17): 3989-98.（影响因子4.0）1.Evaluation of the Association of Zoonotic Ljungan Virus with Perinatal Deaths and Fetal Malformation.Lili Zheng,Fang Wang, Jing Huang, and Hong Xin.Birth Defects Research (Part C). 105:81–85, 2015, IF 3.4512.The termination of gestational weeks and methods of delivery of severe pneumonia in pregnancy.Jing Huang, FangWang, Lili Zheng and Hong Xin.Women’s Health & Gynecology.2016.2(3):025.3.Long noncoding RNA colon cancer associated transcript-1 promotes the proliferation, migration and invasion ofcervical cancer. Ligang Jia, Yuan Zhang, Fei Tian, Zhaoping Chu, Hong Xin. Molecular Medicine Reports,2017,16, 5587-5591. https://doi.org/10.3892/mmr.2017.7302 IF 1.6924. Maternal and neonatal outcomes of placenta increta and percreta from a multicenter study in China, HuijingZhang, Ruochong Dou, Huixia Yang, Xianlan Zhao, Dunjin Chen, Yilin Ding, Hongjuan Ding.Shihong Cui, WeisheZhang, Hong Xin, Weirong Gu, Yali Hu, Guifeng Ding, Hongbo Qi, Ling Fan, Yuyan Ma, Junli Lu, Ye Yang, Li Lin,Xiucui Luo, Xiaohong Zhang & Shangrong Fan .The Journal of Maternal-Fetal & NeonatalMedicine, 2018.10.1080/**.2018.**. IF 1.826（ multi-center cooperation ,Published online）5.Continuous Hyperemesis Gravidarum May be Gastric Cancer during Pregnancy. Fang Wang, Hongfang Kong,Yuan Su, Lili Zheng, Hong Xin. SciFed Obstetrics & Women Healthcare Journal. （accepted）6 Hong Xin, Yi Zhang, Huilan Wang, Shuhan Sun, Alterations of profibrinolytic receptor annexin A2 in pre-eclampsia: A possible role in placental thrombin formation, Thrombosis Research, 2012, 129(5):563-567. 2012; (11): 1273-1275.7 Wu Y, Liu S, Xin H, et al. Up-regulation of microRNA-145 promotes differentiation by著作：主编和参编《妇产科学专升本教材（卫生部和教育部）》、《妊娠合并症及并发症》、《边缘血液病学》、《助产》、《难产》、《孕产妇必读》和《现代精神病学》等多部学术著作。招生要求：全日制本科毕业生及长学制在读生。

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科研及文章列表：编号科研或文章类型科研或文章名称作者排序发表时间
3126 SCI期刊论文 Long noncoding RNA colon cancer associated transcript1 promotes the proliferation, migration and invasion of cervical cancer 通讯作者 201710
3134 SCI期刊论文 Effect of Menopausal Hormone Therapy on Bone Mineral Density in Chinese Women: A 2-Year, Prospective, Open-Label, Randomized-Controlled Trial 通讯作者 201907
3136 SCI期刊论文 Vitexin ameliorates preeclampsia phenotypes by inhibiting TFPI-2 and HIF-1α/VEGF in a l-NAME induced rat model. 通讯作者 201912
3139 SCI期刊论文 CircTRNC18 inhibits trophoblast cell migration and epithelial-mesenchymal transition by regulating miR-762/Grhl2 pathway in pre-eclampsia 通讯作者 201911
3141 SCI期刊论文 The involvement of FBP1 in prostate cancer cell epithelial mesenchymal transition, invasion and metastasis by regulating the MAPK signaling pathway 通讯作者 201910
3144 SCI期刊论文 Down-regulated RBM5 inhibits bladder cancer cell apoptosis by initiating an miR-432-5p/b-catenin feedback loop 通讯作者 201907