杨凌 简介

杨凌，男，汉族，博士，教授，1967年11月出生，河北永年人。1991年7月毕业于河北农业大学畜牧兽医系畜牧专业，2005年12月获河北农业大学动物营养与饲料科学专业农学硕士学位，2010年1月中国农业大学动物遗传育种与繁殖专业博士研究生毕业。2013年7月-8月到澳大利亚新南威尔士大学进修一个月。河北省畜牧兽医学会养牛分会副会长，河北省畜牧兽医学会动物繁殖分会副会长。河北省畜牧业协会羊业分会常务理事。河北省自然科学基金会评专家，国际期刊Theriogenology、 Animals、Livestock Science审稿专家。畜牧学一级学科带头人、负责人。国家级科技特派员，河北科技110专家服务团专家。
一、 主要招生专业及研究方向
主要招生专业：畜牧学、农业硕士—畜牧领域
主要研究方向：动物繁殖生物技术
二、主要成果
1. 提高山羊妊娠产羔率的研究，邯郸市山区创业三等奖（市级），第一，2014年；
2．邯郸县奶业产业化技术集成与示范，河北省科技厅（省级），第二，2011年；
3．獭兔优秀杂交组合筛选及提高养殖效益技术，河北省山区创业三等奖（省级），第三，2012年
4．山区奶牛良种繁育关键技术研究与示范，河北省科技厅（省级），第一，2016年；
5．绵羊妊娠早期胸腺和骨髓表达ISG15和PIBF的研究，河北省自然科学基金面上项目，2016年，第一；
6. 绵羊附植前胚胎形态变化的分子调控机制（**），国家自然科学基金面上项目，2010，参与。
三、承担的课题
1. 2018-2019，山区奶牛繁殖标准化生产技术研究与示范，河北科技厅科技计划项目，30万，主持；
2. 2016-2018，绵羊妊娠早期脾脏表达Th2细胞因子的研究，河北省高等学校科学技术研究重点项目，5万，主持。
四、代表性论文：
1. Bai Jiachen, Zhang Leying, Zhao Zimo, Li Ning, Wang Bin, Yang Ling*. Expression of melatonin receptors and CD4 in the ovine thymus, lymph node, spleen and liver during early pregnancy. Immunology. 2020, 160: 52-63.
2. Yang Ling, Wang Qingkai, Cui Maosheng*, Li Qianjun, Mu Shuqin, Zhao Zimo. Effect of Melatonin on the In Vitro Maturation of Porcine Oocytes, Development of Parthenogenetically Activated Embryos, and Expression of Genes Related to the Oocyte Developmental Capability. Animals, 2020, 10: 209.
3. Yang Ling*, Li Ning, Zhang Leying, Bai Jiachen, Zhao Zimo, Wang Yujiao. Effects of early pregnancy on expression of interferon-stimulated gene 15, STAT1, OAS1, MX1 and IP-10 in ovine liver. Animal Science Journal, 2020, 91:e13378.
4. Zhang Leying, Cao Lidong, Yang Fei, Han Xu, Wang Yujiao, Cao Nan, Yang Ling*. Relative abundance of interferon-stimulated genes STAT1, OAS1, CXCL10 and MX1 in ovine lymph nodes during early pregnancy. Animal Reproduction Science, 2020, 214: 106285.
5. Yang Ling*, Han Xu, Zhang Leying, Li Ning, Zhao Zimo, Bai Jiachen. Changes in expression of prostaglandin synthase in ovine liver during early pregnancy. Canadian Journal of Animal Science, 2020, online, https://doi.org/10.1139/CJAS-2019-0171.
6. Yang Ling, Yao Xiaolei, Chen Xiaoyong*, Zang Shengqin, Sun Hongxin, Liu Yue, Dun Weitao*. Expression of Follicle-stimulating Hormone, Luteotropic Hormone, Estrogen and Progesterone Receptors in Ovary, Oviduct and Endometrium After Estrus Induction in Ewe. Kafkas Univ Vet Fak Derg, 2020, 26 (1): 65-70.
7. Zhang Leying, Zhao Zimo, Mi Hao, Liu Baoliang, Wang Bin, Yang Ling*. Modulation of Helper T Cytokines in Thymus during Early Pregnancy in Ewes. Animals, 2019, 9:245.
8. Yang Ling*, Lv Wan, Liu Yong, Chen Kai, Xue Jie, Wang Qingkai, Wang Bin, Zhang Leying. Effect of early pregnancy on the expression of prostaglandin synthases in the ovine thymus. Theriogenology, 2019, 136: 166-171.
9. WangYujiao, Han Xu, Zhang Leying, Cao Nan, Cao Lidong, Yang Ling*. Early Pregnancy Induces Expression of STAT1, OAS1 and CXCL10 in Ovine Spleens. Animals, 2019, 9: 882.
10. Zhang Leying, Zhuang Chen, Zhao Zimo, Li Ning, Bai Jiachen, Yang Ling*. Effect of early pregnancy on the expression of progesterone receptor and progesterone-induced blocking factor 1 in ovine liver. Czech Journal of Animal Science, 2019, 64 (7): 317-323.
11. Yang Ling*, Wang Qingkai, Liu Yong, Zhang Leying, Lv Wan, Liu Baoliang. Expression profiles of interferon-stimulated gene 15 and prostaglandin synthases in the ovine lymph nodes during early pregnancy. Molecular Reproduction and Development, 2019, 86: 100-108.
12. Yang Ling*, Pengda Wang, Mi Hao, Lv Wan, Liu Baoliang, Du Jinsong, Zhang Leying. Comparison of Th1 and Th2 cytokines production in ovine lymph nodes during early pregnancy. Theriogenology, 2019, 123: 177-184.
13. Yang Ling*, Bai Jiachen, Zhao Zimo, Li Ning, Wang Yujiao, Zhang Leying. Differential expression of T helper cytokines in the liver during early pregnancy in sheep. Animal Reproduction, 2019, 16: 332-339.
14. Yang Ling, He Kaili, Li Jianbin*, Ma Yabin, Li Rongling, Hou Minghai, Gao Yundong, Zhong Jifeng. Correlation of Antibody Levels with Peripheral Lymphocyte Subsets and Routine Hematological Parameters after Vaccination with FMD Vaccine in Young Sires. Pakistan Veterinary Journal, 2019, 39(2): 251-255.
15. Li Ning, Zhao Zimo, Bai Jiachen, Liu Baoliang, Mi Hao, Zhang Leying, Li Guiping, Yang Ling*. Characterization of the Th cytokines profile in ovine spleen during early pregnancy. Journal of Applied Animal Research, 2019, 47: 386-393.
16. Yang Ling, Guo Ruiqing, Ju Zhihua, Wang Xiuge, Jiang Qiang, Liu Yong, Zhao Han, He Kaili, Li Jianbin, Huang Jinming*. Production of an aberrant splice variant of CCL5 is not caused by genetic mutation in the mammary glands of mastitis-infected Holstein cows. Molecular Medicine Reports, 2019, 19: 4159-4166.
17. Zhang Leying, Xue Jie, Wang Qingkai, Lv Wan, Mi Hao, Liu Yong, Yang Ling*. Changes in expression of ISG15, progesterone receptor and progesterone-induced blocking factor in ovine thymus during early pregnancy. Theriogenology, 2018, 121: 153-159.
18. Yang Ling*, Wang Yongxiang, Li Shujing, Zhu Meixia, He Kaili, Yao Xiaolei, Zhang Leying. Differential expression of interferon-gamma, IL-4 and IL-10 in peripheral blood mononuclear cells during early pregnancy of the bovine. Reproductive Biology, 2018, 18:312-315.
19. Yang Ling*, Guo Runqing, Yao Xiaolei, Yan Jinkun, Bai Ying, Zhang Leying. Expression of progesterone receptor and progesterone-induced blocking factor in the spleens during early pregnancy in ewes. Livestock Science, 2018, 209:14-19.
20. Yang Ling, Liu Zhichao, Li Jianbin*, He Kaili, Kong Lingna, Guo Runqing, Liu Wenjiao, Gao Yundong, Zhong Jifeng. Association of expression of Th cytokines with peripheral CD4 and CD8 lymphocyte subsets after vaccinated with FMD vaccine in Holstein young sires. Research in Veterinary Science, 2018, 119: 79-84.
21. Yang Ling*, Liu Yong, Lv Wan, Wang Pengda, Wang Bin, Xue Jie, Zhang Leying. Expression of interferon‐stimulated gene 15-kDa protein, cyclooxygenase (COX) 1, COX-2, aldo-keto reductase family 1, member B1, and prostaglandin E synthase in the spleen during early pregnancy in sheep. Animal Science Journal, 2018, 89:1540-1548.
22. Yang Ling*, Zang Shengqin, Bai Ying, Yao Xiaolei, Zhang Leying. Effect of early pregnancy on the expression of progesterone receptor and progesterone-induced blocking factor in ovine lymph node. Theriogenology, 2017, 93:78-83.
23. Yang Ling*, Liu Baoling, Yan Xianxi, Zhang Leying, Gao, Feng Liu Zhichao. Expression of ISG15 in Bone Marrow During Early Pregnancy in Ewes. Kafkas Univ Vet Fak Derg, 2017, 23 (5): 767-772.
24. Zhang Leying, Mi Hao, Yan Jinkun, Yan Xianxi, Yang Ling*. Pregnancy-associated changes in expression of progesterone receptor and progesterone-induced blocking factor genes in bone marrow of ewes. Animal Reproduction Science, 2017, 186:77-84.
25. Yang Ling*, Yao XiaoLei, Li ShuJing, Chen Kai, Wang YongXiang, Chen Long, Zhang LeYing. Expression of genes associated with luteolysis in PBMCs during early pregnancy in cattle. Molecular Reproduction and Development, 2016, 83(6):509-515.
26. Yang Ling, Wang Yongxiang, Ma Xingshu, Wang Songping, Zhang Leying*. Changes in expression of Th1 and Th2 cytokines in bovine peripheral blood mononuclear cells during early pregnancy, Indian Journal of Animal Research, 2016, 50 (4): 466-470.
27. Zhang L, Xia Y, Tang F, Li SJ, Yang L*. Wang B*. The regulation of intrauterine immune chemokines during early pregnancy in the bovine. Large Animal Reviews, 2015, 21: 23-31.
29. Yang Ling, Tang Fang, Liu Lan, Zhao Weimin, Tang Yiting, Cheng Ying, Wei Jingliang, Yang Shulin, Mu Yulian*, Feng Shutang, Li Kui. Effect of knockdown TAGLN on the migration capacity of Wuzhishan pig’s bone marrow mesenchymal stem cells. Kafkas Univ Vet Fak Derg, 2014, 20 (5): 809-815.
30. Yang Ling, Xia Ying, Tao Xiaoli, He Wei, Wu Tianwen, Huang Lei, Ruan Jinxue, Yang Shulin, Mu Yulian*, Li Kui, Feng Shutang. Knockdown Fascin impairs bone marrow mesenchymal stem cells migration capacity of Wuzhishan Miniature pig. Indian Journal of Animal Sciences, 2014, 84 (10): 1055-1060.
31. Yang Ling, Zhang Leying, Wang Chengming, Wang Bin, Wang Xuemin, Zeng Shenming*. Differential expression pattern of ISG15 in different tissue explants and cells induced by various interferon. Microbiology and Immunology, 2012, 56(3):163-170.
32. Yang Ling*, Wang Bin, Shi Yuxiang, Zhang Leying. Lack of internucleosomal DNA fragmentation induced by cloprostenol in bovine luteal explants in vitro. Indian Journal of Animal Sciences, 2012, 82 (1): 55-57.
33. Yang L, Wang XL, Wan PC, Zhang LY, Wu Y, Tang DW, Zeng SM. Up-regulation of expression of interferon-stimulated gene 15 in the bovine corpus luteum during early pregnancy. Journal of Dairy Science, 2010, 93:1000-1011.
34. Yang Ling*, Li Jianguo, Wang Bin, Zhang Leying. Expression of interferon-stimulated gene 15 in endometrial explants from early pregnant cows in vitro for 60 days. Journal of Animal and Veterinary Advances, 2010, 9(24): 3016-3020.
五、联系方式：
地址：河北省邯郸市经开区太极路19号河北工程大学生命学院，邮编：056038
E-mail: yangling@hebeu.edu.cn