姓 名
陈宬
性 别
男
民 族
汉
出生年月
1984.09
职 称
副研究员
职 务
副研究员
联系电话
**
单位名称
武汉理工大学材料复合新技术国家重点实验室
chengchen@whut.edu.cn
实验室网址
研究方向
主要致力于金属有机化学与材料化学，均相与非均相催化及其在生物活性分子中的应用，有机合成与药物化学。
教育背景
(1) 2008.08 - 2012.10：新加坡南洋理工大学化学专业博士；
(2) 2006.09 - 2008.06：武汉大学分析化学专业硕士；
(3) 2002.09 - 2006.06：武汉大学应用化学专业学士。
工作经历
(1) 2016年11月至今：
武汉理工大学材料复合新技术国家重点实验室、副研究员；
(2) 2016年01月- 2016年10月：
武汉理工大学材料复合新技术国家重点实验室、助理研究员；
(3) 2013年12月- 2015年12月：
华中师范大学、博士后；
(4) 2012年12月-2013年11月：
法国巴黎综合理工大学（部分研究在法国巴黎高师完成）、博士后。
项目情况
(1) 武汉理工大学ESI前1%学科水平提升计划项目(化学学科)，项目负责人，15万，2019.01-2019.12。
(2) 武汉理工大学自主创新基金（WUT: 2017IVA091），新型金属有机骨架材料的制备及其在酰胺键合成中的应用，项目负责人，5万，2017.01-2.017.12；
(3) 武汉理工大学海外优秀博士科研启动基金（）：均相与非均相钌催化剂的制备及应用，项目负责人，35万，2016.01-2018.12；
(4) 国家自然基金青年基金项目（**），结构多样性酰胺类化合物库的构建与新型SDH抑制剂的发现，项目负责人，21万直接费用，2016.01-2018.12；
(5) 第50批教育部“留学回国人员科研启动基金”[教外司留(2015) 1098 号]，高效、高原子经济性合成具有潜在生物活性的噻唑酰胺类化合物，项目负责人，3万，2015.06-2017.12。
(6) 中国博士后第56批面上项目（2014M562044），伯醇与腈为反应原料的新型酰胺合成法及其应用，项目负责人，5万，2013.12- 2015.12；
(7) 湖北省自然科学基金面上项目青年基金（2014CFB280），新型高原子经济性的酰胺键合成法及其在农药合成中的应用，项目负责人，3万，2014.1- 2015.12。
代表性学术
成果
1) Hua Cheng, Maoqian Xiong, Ni Zhang, Huajing Wang, Yang Miao, Wei Su, Ye Yuan, Cheng Chen*, and Francis Verpoort*, Efficient N-heterocyclic carbene/ruthenium catalytic systems for the alcohol amidation with amines: Involvement of poly-carbene complexes? ChemCatChem, 2018, DOI: 10.1002/cctc..
2) Hua Cheng, Wei Song, Ren Nie, Yuxia Wang, Huilian Li, Xiangsheng Jiang, Junjun Wu, Cheng Chen*, Qiongyou Wu*. Synthesis of new 4-aryloxy-N-arylanilines and their inhibitory activities against succinate-cytochrome c reductase. Bioorg. Med. Chem. Lett. 2018, 28, 1330.
3) Hua Cheng, Maoqian Xiong, Chuanxiang Cheng, Huajing Wang, Qiang Lu, Hongfu Liu, Fubin Yao, Cheng Chen*, Francis Verpoort*. In situ generated ruthenium catalytic systems bearing diverse N-heterocyclic carbene precursors for the atom-economic amide synthesis from alcohols and amines. Chem. Asian J., 2018, 13, 440–448.
4) Ye Yuan, Yu Xie, Cheng Zeng, Dandan Song, Somboon Chaemchuen, Cheng Chen*, Francis Verpoort*, A Recyclable AgI/OAc- Catalytic System for the Efficient Synthesis of α-Alkylidene Cyclic Carbonates: Carbon Dioxide Conversion at Atmospheric Pressure, Green Chem. 2017, 19, 2936-2940.
5) Wei Su, Hussein A. Younus, Kui Zhou, Zafar A. K. Khattak, Somboon Chaemcheun, Cheng Chen*, and F. Verpoort*, Chemical and Photochemical Water Oxidation Catalyzed by Novel Ruthenium Complexes Comprising a Negatively Charged NCNHCO Ligand, Catal. Sci. Technol. 2017, 7, 387-395.
6) Ye Yuan, Yu Xie, Cheng Zeng, Dandan Song, Somboon Chaemchuen, Cheng Chen*, Francis Verpoort*, A simple and robust AgI/KOAc catalytic system for the carboxylative assembly of propargyl alcohols and carbon dioxide at atmospheric pressure. Catal. Sci. Technol. 2017, 7, 2935-2939.
7) Hua Cheng, Ren Nie, Wanqiang Wang, Lin Huang, Ke Liu, Cheng Chen*, Wu, Qiongyou*. Research Progress in Structural Modification of Antimycin A. Chin. J. Org. Chem. 2017, 37, 1368.
8) Cheng Chen, Pullaiah Kattanguru, Olesya A. Tomashenko, Rafa? Karpowicz, Gabriela Siemiaszko, Ahanjit Bhattacharya, Vinícius Calasansa and Yvan Six. Synthesis of functionalised azepanes and piperidines from bicyclic halogenated aminocyclopropane derivatives. Org. Biomol. Chem., 2017, 15, 5364.
9) Cheng Chen, Qiong-You Wu,* Lian-Ying Shan, Bei Zhang, Francis Verpoort, Guang-Fu Yang*. Discovery of cytochrome bc1 complex inhibitors inspired by the natural product karrikinolide. RSC Adv. 2016, 6, 97580.
10) Cheng Chen, Francis Verpoort*, Qiongyou Wu*. Atom-Economic Dehydrogenative Amide Synthesis via Ruthenium Catalysis. RSC Adv. 2016, 6, 55599.
11) Cheng Chen, Rui Zhang, Long Lin, Guang-Fu Yang*, Qiong-You Wu*. Br?nsted Acid Promoted One-Pot Synthesis of 4-Aryl-3,4-Dihydrocoumarins. Tetrahedron 2016, 72, 3917.
12) Cheng Chen, Min Ha Kim, Soon Hyeok Hong*. N-Heterocyclic Carbene-Based Ruthenium-Catalyzed Direct Amidation of Aldehydes with Amines. Org. Chem. Front. 2015, 2, 241.
13) Cheng Chen, Soon Hyeok Hong*. Selective Catalytic sp3 C-O Bond Cleavage with C-N Bond Formation in 3-Alkoxy-1-propanols. Org. Lett.2012, 14, 2992.
14) Cheng Chen, Yao Zhang, and Soon Hyeok Hong*. N-Heterocyclic Carbene Based Ruthenium-Catalyzed Direct Amide Synthesis from Alcohols and Secondary Amines - Involvement of Esters. J. Org. Chem.2011, 76, 10005.
15) Cheng Chen, Soon Hyeok Hong*. Oxidative Amide Synthesis Directly from Alcohols with Amines.” Org. Biomol. Chem. 2011, 9, 20.
16) Cheng Chen, Shu-Lin Liu, Ran Cui, Bi-Hai Huang, Zhi-Quan Tian, Peng Jiang, Dai-Wen Pang, Zhi-Lin Zhang*. Diffusion Behaviors of Water-Soluble CdSe/ZnS Core/Shell Quantum Dots Investigated by Single-Particle Tracking. J. Phys. Chem. C. 2008, 112, 18904.
17) 杨光富，陈宬，沈艳青，熊茂钱，一种噻唑双酰胺类化合物及其制备方法和应用"，中国发明专利，申请号，4.9，申请日：2015年6月24日（导师为第一完成人）。
Assoc. Prof. Dr. Cheng Chen
Address: 122 Luoshi Road, Wuhan, Hubei 430070 PR China
Email：chengchen@whut.edu.cn Tel: **
EDUCATION
Year
Institution
Major / Degree
2008.08 - 2012.10
School of Physical and Mathematic Sciences, Nanyang Technological University, Singapore
Chemistry;
Ph. D.
2006.09 - 2008.06
College of Chemistry and Molecular Sciences, Wuhan University, P. R. China
Analytical Chemistry;
Master of Science
2002.09 - 2006.06
College of Chemistry and Molecular Sciences, Wuhan University, P. R. China
Applied Chemistry;
Bachelor of Science
WORK EXPERIENCE
Year
Institution
Title
2016.11 - present
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing,
Associate Professor
2016.01 - 2016.10
Assitant Professor
2013.12 - 2015.12
Department of Chemistry,
Central China Normal University
Postdoc
2012.12 - 2013.11
Département de Chimie et Synthèse Organique, école Polytechnique, France (collaborated with école Normale Supérieure, France) Postdoc
RESEARCH PROJECT
? Wuhan University of Technology ESI improving project，Project leader, 2019.01-2019.12, 150000 RMB;
? The fundamental research funds for the central universities (WUT: 2017IVA091), Project leader, 2017.01-2.017.12, 50000 RMB;
? Wuhan University of Technology research funds for overseas young scholars（）, Project leader, 2016.01-2018.12, 350000 RMB;
? National Natural Science Foundation of China (Project No.: **), 2016.1.1-2018.12.31, Project leader, 210000 RMB;
? China Postdoctoral Science Foundation (Project No.: 2014M562044), 2013.12-2015.12, Project leader, 50000 RMB;
? Natural Science Foundation of Hubei Province funded by Science and Technology Department of Hubei Province (Project No.: 2014CFB280), 2014.1-2015.12, Project leader, 30000 RMB;
? The 50th Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry (authorized date: June 1st, 2015), Project leader, 30000 RMB.
SELECTED PUBLICATION
1) Hua Cheng, Maoqian Xiong, Ni Zhang, Huajing Wang, Yang Miao, Wei Su, Ye Yuan, Cheng Chen*, and Francis Verpoort*, Efficient N-heterocyclic carbene/ruthenium catalytic systems for the alcohol amidation with amines: Involvement of poly-carbene complexes? ChemCatChem, 2018, DOI: 10.1002/cctc..
2) Hua Cheng, Wei Song, Ren Nie, Yuxia Wang, Huilian Li, Xiangsheng Jiang, Junjun Wu, Cheng Chen*, Qiongyou Wu*. Synthesis of new 4-aryloxy-N-arylanilines and their inhibitory activities against succinate-cytochrome c reductase. Bioorg. Med. Chem. Lett. 2018, 28, 1330.
3) Hua Cheng, Maoqian Xiong, Chuanxiang Cheng, Huajing Wang, Qiang Lu, Hongfu Liu, Fubin Yao, Cheng Chen*, Francis Verpoort*. In situ generated ruthenium catalytic systems bearing diverse N-heterocyclic carbene precursors for the atom-economic amide synthesis from alcohols and amines. Chem. Asian J., 2018, 13, 440–448.
4) Ye Yuan, Yu Xie, Cheng Zeng, Dandan Song, Somboon Chaemchuen, Cheng Chen*, Francis Verpoort*, A Recyclable AgI/OAc- Catalytic System for the Efficient Synthesis of α-Alkylidene Cyclic Carbonates: Carbon Dioxide Conversion at Atmospheric Pressure, Green Chem. 2017, 19, 2936-2940.
5) Wei Su, Hussein A. Younus, Kui Zhou, Zafar A. K. Khattak, Somboon Chaemcheun, Cheng Chen*, and F. Verpoort*, Chemical and Photochemical Water Oxidation Catalyzed by Novel Ruthenium Complexes Comprising a Negatively Charged NCNHCO Ligand, Catal. Sci. Technol. 2017, 7, 387-395.
6) Ye Yuan, Yu Xie, Cheng Zeng, Dandan Song, Somboon Chaemchuen, Cheng Chen*, Francis Verpoort*, A simple and robust AgI/KOAc catalytic system for the carboxylative assembly of propargyl alcohols and carbon dioxide at atmospheric pressure. Catal. Sci. Technol. 2017, 7, 2935-2939.
7) Hua Cheng, Ren Nie, Wanqiang Wang, Lin Huang, Ke Liu, Cheng Chen*, Wu, Qiongyou*. Research Progress in Structural Modification of Antimycin A. Chin. J. Org. Chem. 2017, 37, 1368.
8) Cheng Chen, Pullaiah Kattanguru, Olesya A. Tomashenko, Rafa? Karpowicz, Gabriela Siemiaszko, Ahanjit Bhattacharya, Vinícius Calasansa and Yvan Six. Synthesis of functionalised azepanes and piperidines from bicyclic halogenated aminocyclopropane derivatives. Org. Biomol. Chem., 2017, 15, 5364.
9) Cheng Chen, Qiong-You Wu,* Lian-Ying Shan, Bei Zhang, Francis Verpoort, Guang-Fu Yang*. Discovery of cytochrome bc1 complex inhibitors inspired by the natural product karrikinolide. RSC Adv. 2016, 6, 97580.
10) Cheng Chen, Francis Verpoort*, Qiongyou Wu*. Atom-Economic Dehydrogenative Amide Synthesis via Ruthenium Catalysis. RSC Adv. 2016, 6, 55599.
11) Cheng Chen, Rui Zhang, Long Lin, Guang-Fu Yang*, Qiong-You Wu*. Br?nsted Acid Promoted One-Pot Synthesis of 4-Aryl-3,4-Dihydrocoumarins. Tetrahedron 2016, 72, 3917.
12) Cheng Chen, Min Ha Kim, Soon Hyeok Hong*. N-Heterocyclic Carbene-Based Ruthenium-Catalyzed Direct Amidation of Aldehydes with Amines. Org. Chem. Front. 2015, 2, 241.
13) Cheng Chen, Soon Hyeok Hong*. Selective Catalytic sp3 C-O Bond Cleavage with C-N Bond Formation in 3-Alkoxy-1-propanols. Org. Lett.2012, 14, 2992.
14) Cheng Chen, Yao Zhang, and Soon Hyeok Hong*. N-Heterocyclic Carbene Based Ruthenium-Catalyzed Direct Amide Synthesis from Alcohols and Secondary Amines - Involvement of Esters. J. Org. Chem.2011, 76, 10005.
15) Cheng Chen, Soon Hyeok Hong*. Oxidative Amide Synthesis Directly from Alcohols with Amines.” Org. Biomol. Chem. 2011, 9, 20.
16) Cheng Chen, Shu-Lin Liu, Ran Cui, Bi-Hai Huang, Zhi-Quan Tian, Peng Jiang, Dai-Wen Pang, Zhi-Lin Zhang*. Diffusion Behaviors of Water-Soluble CdSe/ZnS Core/Shell Quantum Dots Investigated by Single-Particle Tracking. J. Phys. Chem. C. 2008, 112, 18904.
PATENT
1) 杨光富，陈宬，沈艳青，熊茂钱，一种噻唑双酰胺类化合物及其制备方法和应用"，中国发明专利，申请号，4.9，申请日：2015年6月24日（导师为第一完成人）。
INTERNATIONAL CONFERENCE
1) “Discovery of Novel Cytochrome bc1 Inhibitors by Structure-based Optimization of Natural Products”. 12th national conference of organic chemistry, Guilin, China, October, 2015 (invited presentation on behalf of Prof. Guang-Fu Yang).
2) “Synthesis and Biological Activities of Thiazole Derivatives”. 11th national conference of organic chemistry, Shanghai, China, October, 2014 (poster presentation).
3) “Synthesis and application of new bicyclic aminocyclopropane scaffolds”, JCO 2013, France, September, 2013 (poster presentation).
4) “Ruthenium Catalyzed Direct Amide Synthesis from Alcohols and Secondary Amines - Involvement of Esters”, 1st NTU-TITech Joint Student Workshop, Japan, June, 2011 (oral presentation and poster presentation, awarded “Best Poster Award”).
5) Cheng Chen, Yao Zhang and Soon Hyeok Hong*, “N-Heterocyclic Carbene Based Ruthenium Catalyzed Direct Amide Synthesis from Alcohols and Secondary Amines – Involvement of Esters”, 3rd Asian-Oceanic Conference on Green and Sustainable Chemistry, Australia, December, 2011 (poster presentation, awarded “Student Poster Award – Second Prize”).
6) Ruthenium Catalyzed Direct Amide Synthesis from Alcohols and Secondary Amines - Involvement of Esters”, Chemistry – People & Opportunities in Singapore, Singapore, July, 2011 (oral presentation).
7) “Ruthenium Catalyzed Direct Amide Synthesis from Alcohols and Secondary Amines”, 6th Asian-European Symposium on Metal Mediated Efficient Reactions, Singapore, June, 2010 (poster presentation).
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