韩颖超 基本情况:

出生年月:1977.4

学位:博士

职称:副研究员

工作院系:新材料研究所/生物材料与工程研究中心

教育经历(从大学开始)

1996年9月～2000年7月,武汉理工大学,获工学学士学位;

2000年9月～2002年7月,武汉理工大学,获工学硕士学位;

2005年3月～2007年12月,武汉理工大学,获工学博士学位;

工作经历

2002年7月～2004年10月,武汉理工大学生物材料与工程研究中心,研究实习员;

2004年11月～2009年10月,武汉理工大学生物材料与工程研究中心,助理研究员;

2010年6月～2012年6月,美国内布拉斯加大学医学中心博士后。

2009年11月～至今, 武汉理工大学生物材料与工程研究中心,副研究员;

研究领域(不多于3个)

纳米生物材料,药物可控释放,纳米医学

科研项目(不多于5项)

国家自然科学基金:稀土掺杂羟基磷灰石纳米粒子荧光探针的制备及应用研究

中央高校基本科研业务费专项资金:稀土元素共掺杂羟基磷灰石纳米粒子及荧光增强效应研究

国家重点实验室开放基金：稀土掺杂羟基磷灰石纳米粒子的可控制备与体内分布代谢规律

代表性论文及著作(不多于10项)

[1]A. Schulz, S. Jaksch, R. Schubel, E. Wegener, Z.Y. Di, Y.C. Han, A. Meister, J. Kressler, A.V. Kabanov, R. Luxenhofer, C.M. Papadakis, R. Jordan. Drug-Induced Morphology Switch in Drug Delivery Systems Based on Poly(2-oxazoline)s . ACS NANO, 2014, 8(3): 2686-2696.

[2]Y.C. Han, X.Y. Wang, H.L. Dai, S.P. Li. Synthesis and luminescence of Eu3+ doped hydroxyapatite nanocrystallines: Effects of calcinations and Eu3+ content. Journal of Luminescence, 2013, 135:281-287

[3]Y.C. Han, X.Y. Wang, H.L. Dai, S.P. Li. Nanosize and Surface Charge Effects of Hydroxyapatite Nanoparticles on Red Blood Cell Suspensions. ACS Appl. Mater. Interfaces, 2012, 4 (9):4616–4622.

[4]Y.C. Han, Z.J. He, A. Schulz, T.K. Bronich, R. Jordan, R. Luxenhofer, A.V. Kabanov. Synergistic Combinations of Multiple Chemotherapeutic Agents in High Capacity Poly(2-oxazoline) Micelles. Mol. Pharmaceutics, 2012, 9 (8): 2302–2313.

[5]R. Luxenhofer, Y.C. Han, A. Schulz, J. Tong, Z.J. He, A.V. Kabanov, R. Jordan. Poly(2-oxazoline)s as polymer therapeutics. Macromol Rapid Commun. 2012, 33(19):1613-1631.

[6]Y.C. Han, X.Y. Wang, S.P. Li. Biocompatible Europium doped Hydroxyapatite Nanoparticles as a Biological Fluorescent Probe. Current Nanoscience, 2010, 6(2): 178-183.

[7]Y.C. Han, X.Y. Wang, S.P. Li. A simple route to prepare stable hydroxyapatite nanoparticles suspension. Journal of Nanoparticle Research, 2009, 11(5): 1235-1240.

[8]I. Bauer, S.P. Li, Y.C. Han, L. Yuan, M.Z. Yin. Internalization of hydroxyapatite nanoparticles in liver cancer cells. Journal of Materials Science: Materials in Medicine, 2008, 19(3): 1091-1095.

[9]美国发明专利: US** B2. RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/β-tricalcium phosphate composite material and preparation method thereof. Li Shipu, Han Yingchao, Yan Yuhua, Wan Tao, Wang Xinyu, Yuan Lin, Dai Honglian, Yan Qiongjiao. 2011.8授权

[10]欧洲发明专利: EP** B1. RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/β-tricalcium phosphate composite material and preparation method thereof. Li Shipu, Han Yingchao, Yan Yuhua, Wan Tao, Wang Xinyu, Yuan Lin, Dai Honglian, Yan Qiongjiao. 2012. 9授权

联系方式:

电话:**, **

E-mail:hanyingchao@whut.edu.cn

工作地址(实验室):武汉理工大学西院逸夫楼7楼
Name: Yingchao Han

Personal information

Date of birth:April, 1977

Education:Doctor Degree of Engineering, Wuhan University of Technology

Major:Biomedical materials

Position:Associate Researcher

Work place:Institute of New Materials/Biomedical Materials and Engineering Center

Education

1996.9-2000.7, Bachelor Degree in Materials Science, Wuhan University of Technology, China

2000-2002, Master Degree in Materials Science, Wuhan University of Technology, China

2005-2007, Doctor Degree in Biomedical Materials, Wuhan University of Technology, China

Positions and Employment

2002.7-2004.10 Researcher Assistant, Wuhan University of Technology, P.R. China

2004.11-2009.10 Assistant Researcher, Wuhan University of Technology, P.R. China

2010.6-2012.6 Postdoctoral Research Fellow, University of Nebraska Medical Center

2009.11-present Associate Researcher, Wuhan University of Technology, P.R. China

Research Area and Interests:

1. Bioceramic and biomedical inorganic nanomaterials

1.1 Synthesis of hydroxyapatite (HAP) powders and fabrication of HAP bioceramics;

1.2 Adsorption properties of HAP nanoparticles to some biomolecules (such as serum albumin, heparin and salic acid) and the interaction of HAP nanoparticles cancer cells;

1.3 Preparation and application of rare earth doped HAP nanoparticles with fluorescent property in cell labelling.

1.4 Applications of HAP nanoparticles as drug or gene carriers

2. Drug delivery nano-carrier system and drug formulation

2.1 Preparation technology of anti-cancer drug loading amphiphilic block micelles formulation;

2.2 Synergistic effects study between multiple anti-cancer drugs

Project:

National Natural Science Foundation of China: Preparation and application of rare earth doped hydroxyapatite nanoparticles fluorescence probe

Fundamental Research Funds for the Central Universities: Study on rare earth elements co-doped hydroxyapatite nanoparticles and fluorescence enhancing effect

Opening fund of State Key Laboratory: Controlled preparation of rare earth doped hydroxyapatite nanoparticle and in vivo biodistribution and metabolism

Selected paper and patent (no more than 10)

[1] A. Schulz, S. Jaksch, R. Schubel, E. Wegener, Z.Y. Di, Y.C. Han, A. Meister, J. Kressler, A.V. Kabanov, R. Luxenhofer, C.M. Papadakis, R. Jordan. Drug-Induced Morphology Switch in Drug Delivery Systems Based on Poly(2-oxazoline)s . ACS NANO, 2014, 8(3): 2686-2696.

[2] Y.C. Han, X.Y. Wang, H.L. Dai, S.P. Li. Synthesis and luminescence of Eu3+ doped hydroxyapatite nanocrystallines: Effects of calcinations and Eu3+ content. Journal of Luminescence, 2013, 135:281-287

[3] Y.C. Han, X.Y. Wang, H.L. Dai, S.P. Li. Nanosize and Surface Charge Effects of Hydroxyapatite Nanoparticles on Red Blood Cell Suspensions. ACS Appl. Mater. Interfaces, 2012, 4 (9):4616–4622.

[4] Y.C. Han, Z.J. He, A. Schulz, T.K. Bronich, R. Jordan, R. Luxenhofer, A.V. Kabanov. Synergistic Combinations of Multiple Chemotherapeutic Agents in High Capacity Poly(2-oxazoline) Micelles. Mol. Pharmaceutics, 2012, 9 (8): 2302–2313.

[5] R. Luxenhofer, Y.C. Han, A. Schulz, J. Tong, Z.J. He, A.V. Kabanov, R. Jordan. Poly(2-oxazoline)s as polymer therapeutics. Macromol Rapid Commun. 2012, 33(19):1613-1631.

[6] Y.C. Han, X.Y. Wang, S.P. Li. Biocompatible Europium doped Hydroxyapatite Nanoparticles as a Biological Fluorescent Probe. Current Nanoscience, 2010, 6(2): 178-183.

[7] Y.C. Han, X.Y. Wang, S.P. Li. A simple route to prepare stable hydroxyapatite nanoparticles suspension. Journal of Nanoparticle Research, 2009, 11(5): 1235-1240.

[8] I. Bauer, S.P. Li, Y.C. Han, L. Yuan, M.Z. Yin. Internalization of hydroxyapatite nanoparticles in liver cancer cells. Journal of Materials Science: Materials in Medicine, 2008, 19(3): 1091-1095.

[9] United States Patent: US** B2. RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/β-tricalcium phosphate composite material and preparation method thereof. Li Shipu, Han Yingchao, Yan Yuhua, Wan Tao, Wang Xinyu, Yuan Lin, Dai Honglian, Yan Qiongjiao. 2011.8 issued.

[10] European Patent: EP** B1. RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/β-tricalcium phosphate composite material and preparation method thereof. Li Shipu, Han Yingchao, Yan Yuhua, Wan Tao, Wang Xinyu, Yuan Lin, Dai Honglian, Yan Qiongjiao. 2012. 9 issued.

Contact information:

Tel:**, **

E-mail:hanyingchao@whut.edu.cn

Address (Lab): 7th floor, YIFU Building, Wuhan University of Technology
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