武汉大学第二临床学院研究生导师网页介绍
章军建
专业技术职称
主任医师
二级教授
院内行政职务
副院长、 神经精神病学教研室主任
国外访学经历
法国洛林大学、Lundbeck institute
所在二级学科名称
神经病学
所在三级
学科名称
神经心理学\认知神经疾病
导师主要研究方向
1、痴呆与血管性认知损害
2、神经心理学
主要学术兼职
（职务及聘任时间）
湖北省医学领军人才 2013
武汉大学珞珈杰出学者 2015
《中国临床神经科学》杂志 副主编2016
主要社会兼职
（职务及聘任时间）
中国医师协会神经内科分会常委、认知障碍专委副主任委员2016
中华医学会神经病学分会“痴呆与认知障碍学组”副组长 2015
中国阿尔茨海默病协会（ADC）副主任委员2017
湖北省痴呆与认知障碍医学临床研究中心 主任2015
湖北省认知神经科学专业委员会 主任委员2018
武汉医学会神经病学会主任委员 2018
联系方式
办公室电话
027-67812885
Email
xsssm@sina.cn
近五年科研情况
近五年发表SCI及统计源以上期刊论文共56篇（本人为第一作者或通讯作者）
（其中SCI收录45篇，累计影响因子123分）

目前承担的项目共 8项（国家级4项，省级5项）

2017湖北省科技进步奖一等奖
近五年有代表性的论文、专著和获奖项等

序
号
成果（论文、专著、获奖项目）名称
成果鉴定、颁奖部门及奖励类别、等级或发表刊物与出版单位、时间
备注如：是否SCI（影响因子）

1
Resveratrol prevents cognitive deficits induced by chronic unpredictable mild stress: Sirt1/miR-134 signalling pathway regulates CREB/BDNF expression in hippocampus in vivo and in vitro.
Behav Brain Res.2018


2
Postoperative intermittent fasting prevents hippocampal oxidative stress and memory deficits in a rat model of chronic cerebral hypoperfusion.
Eur J Nutr.2018


3
Frequency-Dependent Changes of the Resting BOLD Signals Predicts Cognitive Deficits in Asymptomatic Carotid Artery Stenosis.
Front Neurosci.2018


4
Intermittent?Fasting?Pretreatment?Prevents?Cognitive Impairment in a?Rat?Model?of?ChronicCerebral?Hypoperfusion.
J Nutr,2017


5
Structural network connectivity impairment and depressive symptoms in?cerebral?small vessel disease.
J Affect Disord,2017


6
The Impact of Carotid Artery Stenting on?Cerebral?Perfusion, Functional Connectivity, and Cognition in Severe Asymptomatic Carotid Stenosis Patients.
Front Neurol.2017


7
Intermittent Fasting Pretreatment Prevents Cognitive Impairment in a Rat Model of Chronic Cerebral Hypoperfusion.
J Nutr.2017


8
Impairments in Brain Perfusion, Metabolites, Functional Connectivity, and Cognition in Severe Asymptomatic Carotid Stenosis Patients: An Integrated MRI Study
Neural Plast?，2017


9
Hypoxia Inducible Factor 1 Promotes Endogenous Adaptive Response in Rat Model of Chronic Cerebral Hypoperfusion
Int.J.Mol.Sci.2017


10
Association of plasma homocysteine, vitamin B12 and folate levels with cognitive function in Parkinson’s disease: A meta-analysis
NEUROSCIENCE LETTERS，2017


11
The Antidepressant Effect of Angelica sinensis Extracts on Chronic Unpredictable Mild Stress-Induced Depression Is Mediated via the Upregulation of the BDNF Signaling Pathway in Rats.
Evid Based Complement Alternat Med.2016


12
Liu X, Zhang J, Sun D, Fan Y, Zhou H, Fu B. Effects of fluoxetine on brain-derived neurotrophic factor serum concentration and cognition in patients with vascular dementia.
Clin Interv Aging, 2014


13
Sun D, Zhang J, Fan Y, Liu X, Gao Y, Wu G, Yan Y, Zeng J. Abnormal levels of brain metabolites may mediate cognitive impairment in stroke-free patients with cerebrovascular risk factors.
Age Ageing, 2014


14
Yang Y, Zhang J, Liu H, Wang J, Xin J, Deng M. Changes in levels of hypoxia-induced mediators in rat hippocampus during chronic cerebral hypoperfusion.
Neurochem Res, 2013


15
Xin J, Zhang J, Yang Y, Deng M, Xie X. Radix Angelica Sinensis that contains the component Z-ligustilide promotes adult neurogenesis to mediate recovery from cognitive impairment.
Curr Neurovasc Res, 2013


16
Xu M, Yang Y, Zhang J. Levels of neuroglobin in serum and neurocognitive impairments in Chinese patients with obstructive sleep apnea.
Sleep Breath, 2013


17
An enriched environment elevates corticosteroid receptor levels in the hippocampus and restores cognitive function in a rat model of chronic cerebral hypoperfusion
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2013


18
Cognitive Improvement Induced byEnvironment Enrichment in Chronic Cerebral Hypoperfusion Rats a Result ofUpregulated Endogenous Neuroprotection
J Mol Neurosci,2015


19
Downregulation of serum brain specific microRNA is associated with
Inflammation and infract volume in acute ischemic stroke
J CLIN NEUROSCI,2015


20
Efficacy of RHO kinase inhibitor on cognitive impairment induced by chronic cerebral hypoperfusion in rats
International journal of clinical and experimental medicine,2015


21
Triptolide attenuates cerebral ischemia and reperfusion injury in rats through the inhibition the nuclear factor kappa signaling pathway
Neuropsychiatric disease and treatment,2015


22
2 NBDG as a marker for detecting glucose uptake in reactive astrocytes exposed to oxygen glucose deprivation in vitro
J Mol Neurosci,2015


23
Abnormal levels of brain metabolites may mediate cognitive impairment in stroke-free patients with cerebrovascular risk factors
Age and Aging,2014


24
Cognitive Changes following Bilateral Deep Brain Stimulation of Subthalamic Nucleus in Parkinson's Disease: A Meta-Analysis.
BIOMED RESEARCH INTERNATIONAL，2016


25
Atherosclerotic?carotid?stenosis?and?cognitive?function
CLINICAL NEUROLOGY AND NEUROSURGERY，2016


26
Vascular risk factors aggravate cognitive impairment in first-ever young ischaemic stroke patients.
EUROPEAN JOURNAL OF NEUROLOGY，2016


27
Meta-analysis?of?BACE1?gene?rs638405?polymorphism?and?the
?risk?of Alzheimer's?disease?inCaucasion?and?Asian?population
NEUROSCIENCE LETTERS，2016


28
Post-occlusion?administration?of?sodium?butyrate?attenuates?cognitive
?impairment?in?a?rat?modelof?chronic?cerebral?hypoperfusion
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR，2015


29
Comparative?analysis?of?general?characteristics?of?ischemic?
stroke?of?BAD?and?non-BAD?CISSsubtypes
JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES，2015


30
http://f.g.wanfangdata.com.cn/download/Periodical_zhyx201115001.aspxhttp://d.g.wanfangdata.com.cn/Periodical_zhyx201115001.aspx基于慢性脑低灌注性脑损伤机制的血管性认知功能损害的防治新策略，

中华医学杂志（专家论坛），2011年15期


31
http://f.g.wanfangdata.com.cn/download/Periodical_zhyx201241001.aspxhttp://d.g.wanfangdata.com.cn/Periodical_zhyx201241001.aspx慢性脑缺血:一个独立的疾病实体?

中华医学杂志（专家论坛），2012年41期


32
混合性认知损害--一个临床新概念。

中华医学杂志（专家论坛），2016年45期http://social.wanfangdata.com.cn/Locate.ashx?ArticleId=zhyx201645005&Name=%e7%ab%a0%e5%86%9b%e5%bb%ba，章军建 ；王涛



33
中国医师协会神经内科分会认知障碍专业委员。
2019年血管性认知障碍诊治指南。（章军建执笔）。
中华医学杂志。2019; 35期。