武汉大学第二临床学院研究生导师介绍
汪付兵
专业技术职称
教授/二级主任技师
院内行政职务
医学检验科副主任、学科与平台办公室副主任
国外访学经历
美国Stanford、UCSD、UCLA
所在二级学科名称
实验诊断学
所在三级
学科名称
临床检验诊断学
导师主要研究方向
1、循环源标志物与肿瘤精准诊疗
2、肿瘤液体活检新技术
3、检验医学分子与数据科学
主要学术兼职
(职务及聘任时间)
1、中国抗癌协会肿瘤标志专业委员会委员,委员;
2、中国研究型医院学会检验医学专业委员会,委员;
3、湖北省医学会检验医学分会,第九届委员;
4、中国医疗保健国际交流促进会循证医学分会,委员;
5、湖北省肝胆疾病学会第一届委员会,委员
主要社会兼职
(职务及聘任时间)
1、湖北省专利奖评审专家组成员
联系方式
办公室电话
027-67813298 18971509896
Email
wfb20042002@sina.com
近五年科研情况
近五年发表SCI及统计源以上期刊论文共 60余 篇(本人为第一作者或通讯作者)
(其中SCI收录 40余 篇,单篇论文最高SCI影响因子 11 分,累计影响因子 160余 分)
目前承担的项目共 10余 项(国家级 4 项)
有代表性的论文、专著和获奖项等
序
号
成果(论文、专著、获奖项目)名称
成果鉴定、颁奖部门及奖励类别、等级或发表刊物与出版单位、时间
备注如:是否SCI(影响因子)
1
湖北省医学青年拔尖人才,第一层次
湖北省卫健委,2019年
2
湖北省杰出青年人才项目
湖北省科技厅,2015年
3
国家发明专利6项
国家专利局
4
Co-administration of sulforaphane and doxorubicin attenuates breast cancer growth by preventing the accumulation of myeloid-derived suppressor cells.
Cancer Letter,2020年
7.36
5
ΔNp63 drives epithelial differentiation in glioma.
Clin. Transl. Med,2020年
7.9
6
Circulating tumor cells in hepatocellular carcinoma single-cell based analysis, preclinical models, and clinical applications
Theranostics,2020年
8.5
7
Beehive-Inspired Macroporous SERS Probe for Cancer Detection through Capturing and Analyzing Exosomes in Plasma
Acs Applied Materiala & Interfaces,2020年
8.6
8
Molecular profiling of pooled circulating tumor cells from prostate cancer patients using dual-antibody-functionalized microfluidic device
Analytical Chemistry,2018年
6.3
9
Ultrasensitive SERS substrate integrated with Uniform Subnanometer Scale “Hot spots” Created by a Graphene Spacer for the Detection of mercury ions
Small,2017年
11.5
10
Recognition and capture of metastatic hepatocellular carcinoma cells using aptamer conjugated quantum dots and magnetic particles.
Biomaterial,2013年
10.3
武汉大学第二临床学院研究生导师网页介绍
刘松梅
专业技术职称
教授
主任技师
院内行政职务
无
国外访学经历
美国芝加哥大学,2016/8-2017/8
所在二级学科名称
临床检验诊断学
所在三级
学科名称
导师主要研究方向
1、肿瘤与代谢性疾病的表观遗传学
2、线粒体与代谢性疾病
主要学术兼职(职务及聘任时间)
中国中西医结合学会检验医学专业委员会内分泌及代谢病检验诊断学术委员会(2015)
中国医师协会检验医师年会线粒体病诊断专家委员会(2015)
中国生物技术协会生物样本库分会(2018)
中国医疗保健国际交流促进会基层检验技术标准化分会“代谢病组学”(2017)
湖北省肝胆疾病学会第一届肝胆诊疗专业委员会(2017)
联系方式
办公室电话
13971452926
Email
smliu@whu.edu.cn
近五年科研情况
近五年发表SCI及统计源以上期刊论文共36篇(本人为第一作者或通讯作者)
(其中SCI收录30篇,单篇论文最高SCI影响因子17.728分,累计影响因子136.649分)
目前承担的项目共 7项(国家级3项,省级3项)
授权发明专利1项
近五年有代表性的论文、专著和获奖项等
序
号
成果(论文、专著、获奖项目)名称
成果鉴定、颁奖部门及奖励类别、等级或发表刊物与出版单位、时间
备注如:是否SCI(影响因子)
1
Maternal Folic Acid Supplementation Mediates Offspring Health via DNA Methylation
Reprod Sci,2020
2.559
2
5-Hydroxymethylcytosines in Circulating Cell-Free DNA Reveal Vascular Complications of Type 2 Diabetes
Clin Chem,2019
6.891
3
Plasma mtDNA copy numbers are associated with GSTK1 expression and inflammation in type 2 diabetes
Diabet Med,2019
3.239
4
Evaluation of serum free fatty acids in chronic renal failure: evidence from a rare case with undetectable serum free fatty acids and population data
Lipids Health Dis,2019
2.651
5
Glucose Is Involved in the Dynamic Regulation of m6A in Patients With Type 2 Diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM,2019
5.605
6
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.
Nature cell biology,2018
17.728
7
Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs.
CLINICAL EPIGENETICS, 2019
5.496
8
Link Between m6A Modification and Cancers.
Frontiers in Bioengineering and Biotechnology, 2018
5.122
9
Insulin/IGF-1R, SIRT1, and FOXOs Pathways-An Intriguing Interaction Platform for Bone and Osteosarcoma.
Frontiers in Endocrinology, 2019
3.634
10
Clinical significance of exosomal miRNAs and proteins in three human cancers with high mortality in China
ONCOLOGY LETTERS, 2019
1.871
11
A Highly Sensitive and Robust Method for Hepatitis B Virus Covalently Closed Circular DNA Detection in Single Cells and Serum
J Mol Diagn,2018
4.88
12
B-RCA revealed circulating miR-33a/b associates with serum cholesterol in type 2 diabetes patients at high risk of ASCVD
Diabetes Res Clin Prac,2018
2.548
13
A sensitive and convenient method for clinical detection of non-syndromic hearing loss-associated common mutations
Gene,2017
2.498
14
Programmable DNA-responsive microchip for the capture and release of circulating tumor cells by nucleic acid hybridization
NANO RESEARCH,2018
7.994
15
Stable isotope labeling - dispersive solid phase extraction - liquid chromatography - tandem mass spectrometry for quantitative analysis of transsulfuration pathway thiols in human serum
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,2018
2.441
16
Increased N(6)-methyladenosine in Human Sperm RNA as a Risk Factor for Asthenozoospermia.
Sci Rep., 2016.
5.228
17
Next-Generation Digital PCR Measurement of Hepatitis B Virus Copy Number in Formalin-Fixed Paraffin-Embedded Hepatocellular Carcinoma Tissue.
2015 Jan;61(1):290-6.
7.911
18
Decreased N6-methyladenosine in peripheral blood RNA from Diabetic Patients Is Associated with FTO Expression Rather than ALKBH5.
2015 Jan;100(1):E148-54.
6.209
19
Transcriptomic and Functional Pathway Analysis of Human Cervical Carcinoma Cancer Cells Response to Microtubule Inhibitor.
J?Cancer.? ,2016
3.609
20
Determination of DNA adenine methylation in genomes of mammals and plants by liquid chromatography/mass spectrometry.
RSC Adv.,2016
3.289
21
Polymorphisms in FADS1 and FADS2 alter plasma fatty acids and desaturase levels in type 2 diabetic patients with coronary artery disease.
J Transl Med,2016
3.694
22
In-hospital free fatty acids levels predict the severity of myocardial ischemia of acute coronary syndrome.
BMC Cardiovasc Disord,2016
1.916
23
Systematic Review and Meta-Analysis: Circulating miRNAs for Diagnosis of Hepatocellular Carcinoma.
J Cell Physiol,2016
4.155
24
Highly Selective Detection of 5-Methylcytosine in Genomic DNA Based on Asymmetric PCR and Specific DNA Damaging Reagents.
Anal Chem.?,2016
5.886
25
Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation.
J Am Soc Nephrol.,2016
8.491
26
Circulating long noncoding RNA GAS5 as a potential biomarker in breast cancer for assessing the surgical effects.
Tumour Biol.?,2016
27
Spatial Analysis and Meta-Analysis of 62 Case-Control Studies from Different Regions
Genes (Basel).?2017
3.600
28
Obtaining More Accurate Signals: Spatiotemporal Imaging of Cancer Sites Enabled by a Photoactivatable Aptamer-Based Strategy
ACS Appl. Mater. Interfaces,2016
7.504
29
Clinically relevant circulating microRNA profiling studies in pancreatic cancer using meta-analysis
Oncotarget,2017
30
Transcriptomic and functional pathways analysis of ascorbate-induced cytotoxicity and resistance of Burkitt lymphoma
Oncotarget.? 2016
31
耐药型HBV感染者临床特征分析
实用医院临床杂志,2019
32
N6-甲基腺嘌呤修饰在临床恶性肿瘤中的研究进展
生命科学,2019
33
HBV感染者检测外周血EBV病毒载量的临床意义
临床肝胆病杂志,2019
34
2型糖尿病患者代谢清除率与血清游离脂肪酸的相关性
现代生物医学进展,2018
35
脂肪酸去饱和酶基因单倍型对2型糖尿病患者血浆脂质和脂肪酸影响的研究
中国糖尿病杂志,2017
36
2型糖尿病患者线粒体呼吸链复合体Ⅰ活性的临床观察
中国糖尿病杂志,2016
37
2016年度医学突出贡献奖
武汉大学医学部,2017
科研突出贡献奖
38
临床生物化学检验实验指导(第4版),编委
中国医药科技出版社,2020
39
检验医学高级教程(第2版),编委
科学出版社,2017
武汉大学第二临床学院研究生导师网页介绍
郑芳
专业技术职称
教授
院内行政职务
检验系(科)副主任/法医司法所副所长
国外访学经历
美国约翰·霍普金斯大学访问学者
所在二级学科名称
临床医学
所在三级
学科名称
临床检验诊断学
导师主要研究方向
心血管疾病的遗传易感性研究与遗传病的分子诊断
主要学术兼职
(职务及聘任时间)
2018中国老年医学会检验分会常委, 2016中国生物化学与分子生物学脂质与脂蛋白专业委员会副委员长,2020中国医学装备协会临床检验装备技术专业委员会常委,2018中国生物物理学会临床分子诊断分会委员、2019中华医学会检验分会教育学组委员
主要社会兼职
(职务及聘任时间)
2017年珞珈特聘教授
联系方式
办公室电话
02767813233
Email
zhengfang@whu.edu.cn
近五年科研情况
近五年发表SCI及统计源以上期刊论文共 28 篇(本人为第一作者或通讯作者)
(其中SCI收录 24 篇,单篇论文最高SCI影响因子 9.986 分,累计影响因子 99.178 分)
目前承担的项目共 6 项(国家级 2 项)
近五年有代表性的论文、专著和获奖项等
序
号
成果(论文、专著、获奖项目)名称
成果鉴定、颁奖部门及奖励类别、等级或发表刊物与出版单位、时间
备注如:是否SCI(影响因子)
1
Liang B, Xiang Y, Zhang X, Wang C, Jin B, Zhao Y, Zheng F*. Systematic pharmacology and GEO database mining revealed the therapeutic mechanism of Xuefu Zhuyu decoration for atherosclerosis cardiovascular disease.
Front Cardiovasc Med. doi: 10.3389/fcvm.2020.552201
SCI, IF: 3.915
2
Qiu X, Xiang Y, Sun J, Wang X, Chen G , Xu X , Liao S, Yang N , Li S , Yang G, Tang Y, Fan J, Xie W, Hu H, Li Y, Zheng F*. Dynamic changes of throat swabs RNA and serum antibodies for SARS-CoV-2 and their diagnostic performances in patients with COVID-19.
Emerg Microbes Infect. 2020 Aug 12; 1-33. doi: 10.1080/22221751.2020.1810133.
SCI, IF:5.776
3
Gong J, Ou J, Qiu X, Jie Y, Chen Y, Yuan L,Cao J, Tan M, Xu W, Zheng F*, Shi Y* and Hu B*. A tool to early predict severe corona virus disease 2019 (COVID-19) : a multicenter study using the risk nomogram in Wuhan and Guangdong, China.
Clinical infectious disease. 2020. doi: 10.1093/cid/ciaa443.
SCI, IF:8.313
4
Rong J, Xu X, Xiang Y, Yang G, Ming X, He S, Liang B, Zhang X, Zheng F*. Thioredoxin-interacting protein promotes activation and inflammation of monocytes with DNA demethylation in coronary artery disease.
J Cell Mol Med. 2020 Feb 10. doi: 10.1111/jcmm.15045.
SCI, IF=4.122
5
Luo J, Zhang X, He S, Lou Q, Zhai G, Shi C, Yin Z*, Zheng F**. Deletion of narfl leads to increased oxidative stress mediated abnormal angiogenesis and digestive organ defects in zebrafish.
Redox Biol. 2020 Jan;28:101355. doi: 10.1016/j.redox.2019.101355.
SCI, IF: 9.986
6
Deng, Qianyun(#); Huang, Wei(#); Peng, Chunyan(#); Gao, Jiajia; Li, Zuhua; Qiu, Xueping; Yang, Na; Yuan, Bifeng(*); Zheng, Fang(*). Genomic 5-mC contents in peripheral blood leukocytes were independent protective factors for coronary artery disease with a specific profile in different leukocyte subtypes.
Clinical Epigenetics, 2018.1.12, 10(1): 9~14.
SCI, IF=5.489
7
Zhang S, Wang XB, Han YD, Xiong CL, Zhou Y, Wang C, Liu ZJ, Yang N, Zheng F*. Polymorphism in ERCC1 confers susceptibility of coronary artery disease and severity of coronary artery atherosclerosis in a Chinese Han population.
Sci Rep. 2017 Jul 25; 7(1): 6407. doi: 10.1038/s41598-017-06732-9. WOS:000425906700001
SCI, IF=4.122
8
临床分子诊断学
人民卫生出版社.2018
郑芳, 王晓春主编
武汉大学第二临床学院研究生导师介绍
李一荣
专业技术职称
专业技术四级
院内行政职务
检验科主任
国外访学经历
2005/03-2006/08,University of Alabama at Birmingham, 博士后
所在二级学科名称
临床检验诊断学
所在三级
学科名称
微生物检验
导师主要研究方向
重要病原体致病机制的研究;炎症与肿瘤
主要学术兼职
(职务及聘任时间)
主要社会兼职
(职务及聘任时间)
2018.01,中国医促会基层检验标准化分会任副主任委员
2017.12,湖北省医学会检验分会副主任委员
2018.03,《中华检验医学杂志》编委
联系方18602718052
办公室电话
Email
liyirong838@163.com
近五年科研情况
近五年发表SCI及统计源以上期刊论文共 41 篇(本人为第一作者或通讯作者)
(其中SCI收录 26 篇,单篇论文最高SCI影响因子47.677分,累计影响因子 157.419 分)
目前承担的项目共 8 项(国家级 4 项)
有代表性的论文、专著和获奖项等
序
号
成果(论文、专著、获奖项目)名称
成果鉴定、颁奖部门及奖励类别、等级或发表刊物与出版单位、时间
备注如:是否SCI(影响因子)
1
Relationship Between serum SARS-CoV-2 nucleic acid(RNAemia) and Organ Damage in COVID-19 Patients: A Cohort Study
Clinical infectious diseases
SCI(8.736)
2
Positive RT-PCR Test Results in Patients Recovered From COVID-19
JAMA
SCI(47.677)
3
?Seroprevalence of SARS-CoV-2 immunoglobulin antibodies in Wuhan, China: part of the city-wide massive testing campaign
?Clinical microbiology and infection
SCI(7.117)
4
?Can routine laboratory tests discriminate SARS-CoV-2-infected pneumonia from other causes of community-acquired pneumonia?
Clinical and translational medicine
SCI(7.919)
5
RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak.
Emerging Microbes & Infections
SCI(6.197)
6
Molecular Characteristics, Virulence Gene and Wall Teichoic Acid Glycosyltransferase Profiles ofStaphylococcus aureus: A Multicenter Study in China
FRONTIERS IN MICROBIOLOGY
SCI(4.236)
7
Molecular characteristics and virulence gene profiles of Staphylococcus aureus isolates in Hainan, China
BMC infectious diseases
SCI(2.96)
8
全国创新争先奖
中华人民共和国科学技术部
9
湖北省科技进步二等奖
湖北省人民政府
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