武汉大学口腔医学院导师教师师资介绍简介-王家伟

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王家伟，医学博士、武汉大学口腔医学院修复科教授、主任医师，博士研究生导师，兼任中华口腔医学会口腔修复学专业委员会常务委员、湖北省口腔医学会口腔修复学专委会副主任委员。主要从事口腔修复和口腔种植的临床、科研、教学工作，熟悉各类传统义齿和种植义齿修复，擅长瓷贴面、全瓷冠桥的美学修复，重度磨耗牙、牙列缺损伴垂直距离丧失的精密固定修复，复杂缺牙和全口缺牙的种植义齿修复，在前牙美学种植、咬合重建、咬合调整等方面有独到经验。2001至2004年在荷兰莱顿大学从事博士后研究，以第一作者或通讯作者身份在国内、外专业学术期刊上发表论文50余篇，主译论著《可摘局部义齿》，参编研究生教材《全口义齿》，先后主持和参与国家、省、市级科研项目10余项，主要学术研究领域为：软骨内成骨、骨组织工程、生物材料骨界面、种植体表面改性等，指导研究生40余名。

[1] 1997.9-2000.6
（原）湖北医科大学|博士
[2] 1994.9-1997.6
（原）湖北医科大学|硕士
[3] 1989.9-1994.6
（原）湖北医科大学|学士

[1] 2010.12-至今
武汉大学口腔医院
[2] 2009.12-2010.11
武汉大学口腔医院
[3] 2004.12-2009.11
武汉大学口腔医院
[4] 2004.10-2004.11
武汉大学口腔医院
[5] 2001.11-2004.9
荷兰莱顿大学
[6] 2000.7-2001.10
武汉大学口腔医院

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[1] 临床基础研究
[2] 骨组织工程支架
[3] 成骨生物学研究

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中文主页 > 科学研究
研究领域

软骨内成骨
骨组织工程
生物材料骨界面研究
种植体表面改性

论文成果
MORE+
Preparation and characterization of electrodeposition calcium phosphate/chitosan coating on Ti6Al4V plates. J Dent Res. 2004. Wang J*, de Boer J, de Groot K.
Biomimetic and electrolytic calcium phosphate coatings on titanium alloy: physicochemical characteristics and cell attachment.. Biomaterials. 2004. Wang J*, Layrolle P, Stigter M, de Groot K.
Electrolytic deposition of calcium phosphate/chitosan coating on titanium alloy: Growth kinetics and influence of current density, acetic acid, and chitosan. J Biomed Mater Res. 2006. Wang J*, van Apeldoorn A, de Groot K.
In vitro degradation of electrodeposited calcium phosphate coatings by osteoclast-like cells. Biomedical Materials. 2012. Long T, Hong F, Shen S, Wang L, Wang Y, Wang J*.
Fabrication of positively charged poly(ethylene glycol)-diacrylate hydrogel as a bone tissue engineering scaffold. Biomedical Materials. 2012. Tan F, Xu X, Deng T, Yin M, Zhang X, Wang J*.

专利
MORE+
一种大孔三维有序取向性丝素蛋白纳米纤维支架. 2014/07/01. ZL 4.4.
一种光照-镁离子双交联海藻酸盐水凝胶及其制备方法. 2016/03/01. ZL 3.8.
大孔三维有序取向性丝素蛋白纳米纤维支架及其制备方法. 2016/04/01. ZL 5.8.
一种简易静电纺丝支架. 2016/11/01.
一种即刻交联技术用于制备大孔三维纳米纤维支架. 2017/02/01. ZL 9.X.

著作成果

可摘局部义齿 .2006/01/01.

科研项目

一种新型“位点保存”材料的应用基础研究. 2015/01/01至2016/01/01.
YAP1在间充质干细胞软骨内成骨中的作用及机制研究. 2016/01/01至2019/01/01.
国家自然科学基金项目. DDIT3对软骨内成骨的调控作用及相关机制研究. 2019/01/01至2022/01/01.

教师博客

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中文主页 > 科学研究 > 研究领域
软骨内成骨
骨组织工程
生物材料骨界面研究
种植体表面改性

教师博客

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中文主页 > 科学研究 > 论文成果
[1]. Preparation and characterization of electrodeposition calcium phosphate/chitosan coating on Ti6Al4V plates. J Dent Res. 2004. Wang J*, de Boer J, de Groot K.
[2]. Biomimetic and electrolytic calcium phosphate coatings on titanium alloy: physicochemical characteristics and cell attachment.. Biomaterials. 2004. Wang J*, Layrolle P, Stigter M, de Groot K.
[3]. Electrolytic deposition of calcium phosphate/chitosan coating on titanium alloy: Growth kinetics and influence of current density, acetic acid, and chitosan. J Biomed Mater Res. 2006. Wang J*, van Apeldoorn A, de Groot K.
[4]. In vitro degradation of electrodeposited calcium phosphate coatings by osteoclast-like cells. Biomedical Materials. 2012. Long T, Hong F, Shen S, Wang L, Wang Y, Wang J*.
[5]. Fabrication of positively charged poly(ethylene glycol)-diacrylate hydrogel as a bone tissue engineering scaffold. Biomedical Materials. 2012. Tan F, Xu X, Deng T, Yin M, Zhang X, Wang J*.
[6]. The design and features of apatite-coated chitosan microspheres as injectable scaffold for bone tissue engineering. Biomedical Materials. 2013. Shen S, Fu D, Xu F, Long T, Hong F, Wang J*.
[7]. Evaluation of apatite-coated chitosan microspheres for bone regeneration. Journal of Wuhan University of Technology-Materials Science Edition. 2014. Xu F, Yin M, Ding H, Song F, Fu D, Zhang J, Wang J*.
[8]. DDIT3 overexpression increases odontoblastic potential of human dental pulp cells. Cell Proliferation. 2014. Wu Y, Sun H, Song F, Fu D, Wang J*.
[9]. Effects of drying methods on the preparation of dexamethasone-loaded chitosan microspheres. Biomedical Materials. Biomedical Materials. 2014. Xu F, Yin M, Wu Y, Ding H, Song F, Wang J*.
[10]. Effects of preparation methods on the bone formation potential of apatite-coated chitosan microspheres.. Journal of Biomaterials Science-Polymer Edition. 2014. Xu F, Ding H, Song F, Wang J*.
[11]. Deletion of Alox5 gene decreases osteogenic differentiation but increases adipogenic differentiation of mouse induced pluripotent stem cells. Cell and Tissue Research. 2014. Wu Y, Sun H, Song F, Huang C, Wang J*.
[12]. Theoretical role of adjunctive implant positional support in stress distribution of distal-extension mandibular removable partial dentures. International Journal of Prosthodontics. 2014. Xiao W, Li Z, Shen S, Chen S, Wang Y, Wang J*.
[13]. Incorporation of magnesium ions into photo-crosslinked alginate hydrogel enhanced cell adhesion ability. Journal of Tissue Engineering and Regenerative Medicine. 2015. Yin M, Xu F, Ding H, Tan F, Song F, Wang J*.
[14]. Influence of connection type on the biomechanical behavior of distal extension mandibular removable partial dentures supported by implants and natural teeth. Computer Methods in Biomechanics and Biomedical Engineering. 2016. Xiao W, Li Z, Shen S, Chen S, Chen S, Wang J*.
[15]. Establishment of 3D culture and induction of osteogenic differentiation of pre-osteoblasts using wet-collected aligned scaffolds. Materials Science & Engineering C-Materials for Biological Applications. 2017. Ding H, Zhong J, Xu F, Song F, Yin M, Wu Y, Hu Q, Wang J*.
[16]. Role of span length in the adaptation of implant-supported cobalt chromium frameworks fabricated by three techniques.. Journal of Advanced Prosthodontics. 2017. Zhou Y, Li Y, Ma X, Huang Y, Wang J*.
[17]. YAP1 negatively regulates chondrocyte differentiation partly by activating the β-catenin signaling pathway. International Journal of Biochemistry. 2017. Yang B, Sun H, Song F, Yu M, Wu Y*, Wang J*.
[18]. Charge density is more important than charge polarity in enhancing osteoblast-like cell attachment on poly(ethylene glycol)-diacrylate hydrogel. Materials Science & Engineering C-Materials for Biological Applications. 2017. Tan F, Liu J, Liu M, Wang J*.
[19]. Influences of microgap and micromotion of implant–abutment interface on marginal bone loss around implant neck. Archives of Oral Biology. 2017. Liu Y, Wang J*.
[20]. Effect of surface charge on osteoblastic proliferation and differentiation on a poly(ethylene glycol)-diacrylate hydrogel. Journal of Materials Science. 2018. Tan F, Liu J, Song K, Liu M, Wang J*.
[21]. Yes-associated protein 1 promotes the differentiation and mineralization of cementoblast. Journal of Cellular Physiology. 2018. Yang B, Sun H, Song F, Wu Y*, Wang J*.
[22]. 5-Lipoxygenase knockout aggravated apical periodontitis in a murine model. Journal of Dental Research. 2018. Wu Y, Sun H, Yang B, Liu X, Wang J*.
[23]. A technique to record the gingival configuration of an interim implant-supported fixed partial denture. Journal of Prosthetic Dentistry. 2018. Huang Y, Han Y, Wang J*.
[24]. Fabrication of three-dimensional nanofibrous gelatin scaffolds using one-step crosslink technique. Journal of Biomaterials Science-Polymer Edition. 2018. Teng F, Ding H, Huang Y, Wang J*.
[25]. Alternative method to evaluate the adaptation of implant-supported multi-unit prosthetic frameworks. Journal of Prosthodontics-Implant Esthetic and Reconstructive Dentistry. 2019. Zhou Y, Li Y, Ma X, Huang Y, Wang J*.
[26]. Proliferation and differentiation of osteoblast-like MC3T3-E1 cells on biomimetically and electrolytically deposited calcium phosphate coatings. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A. 90A (3). 2009.
[27]. In vitro degradation of electrodeposited calcium phosphate coatings by osteoclast-like cells. BIOMEDICAL MATERIALS. 7 (4). 2012.
[28]. Electrolytic deposition of lithium into calcium phosphate coatings. DENTAL MATERIALS. 25 (3). 2009.
[29]. Early bone apposition and 1-year performance of the electrodeposited calcium phosphate coatings: an experimental study in rabbit femora. CLINICAL ORAL IMPLANTS RESEARCH. 21 (9). 2010.
[30]. Animal experiment or cp titanium with thin hydroxyapatite layers.. JOURNAL OF DENTAL RESEARCH. 80 (4). 2001.
[31]. Esthetic Restoration of Multiple Congenitally Missing Anterior Teeth with Oral Implants: A Clinical Case Report. INTERNATIONAL JOURNAL OF PROSTHODONTICS. 29 (6). 2016.
[32]. Ddit3 suppresses the differentiation of mouse chondroprogenitor cells. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 81. 2016.
[33]. 电化学沉积钙磷涂层及钙磷/壳聚糖涂层的体外降解. 中华口腔医学杂志. 2008.
[34]. 微球细胞支架在骨组织工程中的应用. 中国组织工程研究与临床康复. 2009.
[35]. 等离子喷涂HA涂层种植体的长期稳定性. 中国口腔种植学杂志. 2009.
[36]. 电化学沉积钙磷涂层在兔股骨内的早期骨结合. 中国组织工程研究与临床康复. 2009.
[37]. 电化学沉积钙磷涂层和钙磷-壳聚糖涂层在兔股骨内的长期效应研究. 口腔医学研究. 2010.
[38]. 种植体类型对下颌游离端义齿应力分布的影响. 实用口腔医学杂志. 2011.
[39]. TiUnite表面种植体的临床研究进展. 国际口腔医学杂志. 2010.
[40]. 正电荷修饰对光交联海藻酸盐水凝胶支架细胞粘附性能的影响. 口腔医学研究. 2014.
[41]. 种植体上部不同结构对下颌游离端义齿应力分布的影响. 实用口腔医学杂志. 2012.
[42]. 不翻瓣口腔种植的研究现状. 国际口腔医学杂志. 2014.
[43]. 乙醇浴“一步交联”法制备明胶三维大孔纳米纤维支架. 口腔医学研究. 2015.
[44]. 长链非编码RNAs与细胞分化. 口腔医学研究. 32 (4). 2017.
[45]. 电化学沉积含锂离子的钙磷涂层. 中国组织工程研究与临床康复. 13 (1673-8225). 2009.
[46]. Procera~冠临床前教学培训的效果评价. 中国现代医生. (1673-9701). 2010.
[47]. 种植体骨界面的生物学研究进展. 中国口腔种植学杂志. (1007-3957). 2001.
[48]. 纯钛阳极氧化及表面薄层羟基磷灰石形成技术的研究 Ⅰ.氧化膜的制备及羟基磷灰石涂层的形成. 中国口腔种植学杂志. (1007-3957). 2001.
[49]. 热压铸入型玻璃陶瓷材料的初步研制Ⅱ.材料的生物安全性评估. 口腔医学纵横. (1000-4661). 2001.

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中文主页 > 科学研究 > 专利
[1]. 一种大孔三维有序取向性丝素蛋白纳米纤维支架. 2014-07-01. ZL 4.4.
[2]. 一种光照-镁离子双交联海藻酸盐水凝胶及其制备方法. 2016-03-01. ZL 3.8.
[3]. 大孔三维有序取向性丝素蛋白纳米纤维支架及其制备方法. 2016-04-01. ZL 5.8.
[4]. 一种简易静电纺丝支架. 2016-11-01.
[5]. 一种即刻交联技术用于制备大孔三维纳米纤维支架. 2017-02-01. ZL 9.X.
[6]. 一种口腔修复体支架制作精度的检测方法. 2018-05-01. ZL 8.5.
[7]. 一种全口义齿颌位记录板. 2018-12-01. ZL 7.3.

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中文主页 > 科学研究 > 著作成果
[1]. 可摘局部义齿.

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中文主页 > 科学研究 > 科研项目
[1]. 一种新型“位点保存”材料的应用基础研究.
[2]. YAP1在间充质干细胞软骨内成骨中的作用及机制研究.
[3]. 国家自然科学基金项目. DDIT3对软骨内成骨的调控作用及相关机制研究.

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